Sleep duration and cancer risk in women

Details

• Alternative Title:
  Cancer Causes Control
• Personal Author:
  Hurley, Susan ; Goldberg, Debbie ; Bernstein, Leslie ; Reynolds, Peggy
• Description:
  The objective was to conduct an analysis of sleep duration and risk of selected site-specific and groups of cancer among a large prospective cohort of California women.|The study population was comprised of 101,609 adult females participating in the California Teachers Study. All sites of invasive cancer prospectively diagnosed from baseline (1995-1996) through 2011 were identified through linkage to the California Cancer Registry (n = 12,322). Site-specific analyses focused on the following cancers: breast (n = 5,053), colorectal (n = 983), lung (n = 820), melanoma (n = 749), and endometrial (n = 957). Additionally, we evaluated a group of estrogen-mediated cancers consisting of breast, endometrial, and ovarian cancer (n = 6,458). Sleep duration was based on self-report of average time sleeping in the year prior to baseline. Cox proportional hazard models were used to calculate adjusted hazard ratios and 95 % confidence intervals (HRs, 95 % CI).|Point estimates for all sites and site-specific cancers generally were near or below one for short sleepers (<6 h/night) and above one for long sleepers (10+ h/night); confidence intervals, however, were wide and included unity. Compared to average sleepers (7-9 h/night), long sleepers had an increased risk of the group of estrogen-mediated cancers (HR 1.22, 95 % CI 0.97-1.54, p (trend) = 0.04).|These analyses suggest that longer sleep may be associated with increased risks of estrogen-mediated cancers. Further studies with more refined measures of sleep duration and quality are warranted.
• Keywords:
  Adult Aged Aged, 80 And Over California Female Humans Middle Aged Neoplasms Proportional Hazards Models Prospective Studies Risk Factors Self Report Sleep Young Adult

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• Source:
  Cancer Causes Control. 26(7):1037-1045
• Pubmed ID:
  25924583
• Pubmed Central ID:
  PMC4466005
• Document Type:
  Journal Article
• Funding:
  HHSN261201000035C/CA/NCI NIH HHSUnited States/ ; HHSN261201000036C/CA/NCI NIH HHSUnited States/ ; U58 DP000807/DP/NCCDPHP CDC HHSUnited States/ ; K05 CA136967/CA/NCI NIH HHSUnited States/ ; HHSN261201000035I/CA/NCI NIH HHSUnited States/ ; R01 CA077398/CA/NCI NIH HHSUnited States/ ; R01 CA77398/CA/NCI NIH HHSUnited States/ ; HHSN261201000034C/CA/NCI NIH HHSUnited States/
• Volume:
  26
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:47e31b14b6c5f10be1b3176aedf68f4977c22ce5dc932f1fc70d88d879501624
• Download URL:
  https://stacks.cdc.gov/view/cdc/42050/cdc_42050_DS1.pdf
• File Type:
  [PDF - 257.99 KB ]