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Effectiveness of a Third Dose of MRNA Vaccines Against COVID-19–associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Adults During Periods of Delta and Omicron Variants Predominance — VISION Network, 10 States, August 2021–January 2022
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January 21, 2022
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Source: MMWR: Morbidity and Mortality Weekly Report 2022; v. 71 Early Release
[PDF-417.21 KB]
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Description:What is already known about this topic? COVID-19 mRNA vaccine effectiveness (VE) in preventing COVID-19 might decline because of waning of vaccine-induced immunity or Variants immune evasion.
What is added by this report? VE was significantly higher among patients who received their second mRNA COVID-19 vaccine dose <180 days before medical encounters compared with those vaccinated ≥180 days earlier. During both Delta- and Omicron-predominant periods, receipt of a third vaccine dose was highly effective at preventing COVID-19–associated emergency department and urgent care encounters (94% and 82%, respectively) and preventing COVID-19–associated hospitalizations (94% and 90%, respectively).
What are the implications for public health practice? All unvaccinated persons should start vaccination as soon as possible. All adults who have received mRNA vaccines during their primary COVID-19 vaccination series should receive a third dose when eligible, and eligible persons should stay up to date with COVID-19 vaccinations.
Suggested citation for this article: Thompson MG, Natarajan K, Irving SA, et al. Effectiveness of a Third Dose of mRNA Vaccines Against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Adults During Periods of Delta and Omicron Variant Predominance — VISION Network, 10 States, August 2021–January 2022. MMWR Morb Mortal Wkly Rep. ePub: 21 January 2022.
mm7104e3.htm?s_cid=mm7104e3_w
mm7104e3-H.pdf
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ISSN:0149-2195 (print);1545-861X (digital);
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Pages in Document:8 pdf pages
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Volume:71
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