COVID-19 Incidence and Death Rates Among Unvaccinated and Fully Vaccinated Adults with and Without Booster Doses During Periods of Delta and Omicron Variants Emergence — 25 U.S. Jurisdictions, April 4–December 25, 2021

Details

• Personal Author:
  Johnson, Amelia G. ; Amin, Avnika B. ; Ali, Akilah R. ; Hoots, Brooke ; Cadwell, Betsy L. ; Arora, Shivani ; Avoundjian, Tigran ; Awofeso, Abiola O. ; Barnes, Jason ; Bayoumi, Nagla S. ; Busen, Katherine ; Chang, Carolyn ; Cima, Mike ; Crockett, Molly ; Cronquist, Alicia ; Davidson, Sherri ; Davis, Elizabeth ; Delgadill0, Janelle ; Dorabawila, Vajeera ; Drenzek, Cherie ; Eisenstein, Leah ; Fast, Hannah E. ; Gent, Ashley ; Hand, Julie ; Hoefer, Dina ; Holtzman, Corinne ; Jara, Amanda ; Jones, Amanda ; Kamal-Ahmed, Ishrat ; Kangas, Sarah ; Kanishka, FNU ; Kaur, Ramandeep ; Khan, Saadiah ; King, Justice ; Kirkendall, Samantha ; Klioueva, Anna ; Kocharian, Anna ; Kwon, Frances Y. ; Logan, Jacqueline ; Lyons, B. Casey ; Lyons, Shelby ; May, Andrea ; McCormick, Donald ; Mendoza, Erica ; Milroy, Lauren ; O’Donnell, Allison ; Pike, Melissa ; Pogosjans, Sargis ; Saupe, Amy ; Sell, Jessica ; Smith, Elizabeth ; Sosin, Daniel M. ; Stanislawski, Emma ; Steele, Molly K. ; Stephenson, Meagan ; Stout, Allen ; Strand, Kyle ; Tilakaratne, Buddhi P. ; Turner, Kathryn ; Vest, Hailey ; Warner, Sydni ; Wiedeman, Caleb ; Zaldivar, Allison ; Silk, Benjamin J. ; Scobie, Heather M.
• Corporate Authors:
  CDC COVID-19 Emergency Response Team Epidemiology Task Force ; Rhode Island Dept. of Health ; Seattle & King County Dept. of Public Health ; District of Columbia Dept. of Health ; Utah Dept. of Health ; New Jersey Dept. of Health ; Michigan. Dept. of Health and Human Services ; New York, NY Dept. of Health and Mental Hygiene ; Arkansas Dept. of Health ; MassachU.S.etts Dept. of Public Health ; Colorado Dept. of Public Health and Environment ; Alabama Dept. of Public Health ; New Mexico Dept. of Health ; New York State Dept. of Health ; Georgia Dept. of Public Health ; Florida Dept. of Health ; COVID-19 Response Team Vaccine Task Force ; Louisiana Dept. of Health ; Minnesota Dept. of Health ; Center for Surveillance, Epidemiology, and Laboratory Services (U.S.) ; Nebraska Dept. of Health and Human Services ; Wisconsin Dept. of Health Services ; Idaho Dept. of Health and Welfare ; Texas Dept. of State Health Services ; Tennessee Dept. of Health ; CDC COVID-19 Emergency Response Team Data Analytics and Visualization Task Force ; Kansas Dept. of Health and Environment ; Indiana Dept. of Health
• Description:
  What is already known about this topic? Although COVID-19 vaccine effectiveness decreased with emergence of the Delta Variants and waning of vaccine-induced immunity, protection against hospitalization and death has remained high.
  
  What is added by this report? In 25 U.S. jurisdictions, decreases in case incidence rate ratios for unvaccinated versus fully vaccinated persons with and without booster vaccine doses were observed when the Omicron Variants emerged in December 2021. Protection against infection and death during the Delta-predominant period against infection during Omicron emergence were higher among booster vaccine dose recipients, and especially among persons aged 50–64 and ≥65 years.
  
  What are the implications for public health practice? COVID-19 vaccination protected against SARS-CoV-2 infection, even as the Omicron Variants became predominant. All eligible persons should stay up to date with COVID-19 vaccination.
  
  Suggested citation for this article: Johnson AG, Amin AB, Ali AR, et al. COVID-19 Incidence and Death Rates Among Unvaccinated and Fully Vaccinated Adults with and Without Booster Doses During Periods of Delta and Omicron Variant Emergence — 25 U.S. Jurisdictions, April 4–December 25, 2021. MMWR Morb Mortal Wkly Rep.
  
  mm7104e2.htm?s_cid=mm7104e2_w
  
  mm7104e2-H.pdf
  
  
• Subjects:
  Adolescent Adult Aged CoronaVirus Infections COVID-19 Vaccines COVID-19/Diagnosis Hospitalization Humans Incidence Middle Aged SARS-CoV-2 Vaccination Vaccination Coverage

  More +
• Source:
  MMWR: Morbidity and Mortality Weekly Report 2022; v. 71 Early Release
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  7 pdf pages
• Volume:
  71
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:ca336213122947a4a7403fed0b3541fc06906ce37968af335ff5d9b41923e0417db3867341b1375f8c1480445e12806a9c6a83a16de3dd1025061562546a551d
• Download URL:
  https://stacks.cdc.gov/view/cdc/113717/cdc_113717_DS1.pdf
• File Type:
  [PDF - 493.78 KB ]