Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Kanji, Jamil N. ; Pabbaraju, Kanti ; Croxen, Matthew ; Detmer, Susan ; Bastien, Nathalie ; Li, Yan ; Majer, Anna ; Keshwani, Hussein ; Zelyas, Nathan ; Achebe, Ifeoma ; Jones, Corinne ; Rutz, Maureen ; Jacobs, Angela ; Lehman, Keith ; Hinshaw, Deena ; Tipples, Graham
• Description:
  Influenza strains circulating among swine populations can cause outbreaks in humans. In October 2020, we detected a variant influenza A subtype H1N2 of swine origin in a person in Alberta, Canada. We initiated a public health, veterinary, and laboratory investigation to identify the source of the infection and determine whether it had spread. We identified the probable source as a local pig farm where a household contact of the index patient worked. Phylogenetic analysis revealed that the isolate closely resembled strains found at that farm in 2017. Retrospective and prospective surveillance using molecular testing did not identify any secondary cases among 1,532 persons tested in the surrounding area. Quick collaboration between human and veterinary public health practitioners in this case enabled a rapid response to a potential outbreak.
• Subjects:
  Animals Humans Influenza, Human Influenza A Virus, H1N1 Subtype Influenza A Virus, H1N2 Subtype Influenza A Virus, H3N2 Subtype Orthomyxoviridae Infections Phylogeny Prospective Studies Retrospective Studies Swine Swine Diseases

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• Source:
  Emerg Infect Dis. 2021; 27(12):3045-3051
• Pubmed ID:
  34808085
• Pubmed Central ID:
  PMC8632177
• Document Type:
  Journal Article
• Place as Subject:
  Alberta, Canada
• Location:
  North America
• Volume:
  27
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:2d5e430e62e9fdfbc3a8c7e16c485ee44f203d1f5d05f70e5b290e1977d43e03
• Download URL:
  https://stacks.cdc.gov/view/cdc/112603/cdc_112603_DS1.pdf
• File Type:
  [PDF - 1.13 MB ]