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SARS-CoV-2 Variants in Immunocompromised Patient Given Antibody Monotherapy
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10 2021
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Source: Emerg Infect Dis. 27(10):2725-2728
[PDF-2.45 MB]
Details:
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Alternative Title:Emerg Infect Dis
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Personal Author:
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Description:A 72-year-old immunocompromised man infected with severe acute respiratory syndrome coronavirus 2 received bamlanivimab monotherapy. Viral evolution was monitored in nasopharyngeal and blood samples by melting curve analysis of single-nucleotide polymorphisms and whole-genome sequencing. Rapid emergence of spike receptor binding domain mutations was found, associated with a compartmentalization of viral populations.
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Pubmed ID:34352197
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Pubmed Central ID:PMC8462331
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Document Type:
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Volume:27
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Issue:10
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