SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hoffman, Seth A. ; Costales, Cristina ; Sahoo, Malaya K. ; Palanisamy, Srikanth ; Yamamoto, Fumiko ; Huang, ChunHong ; Verghese, Michelle ; Solis, Daniel A. ; Sibai, Mamdouh ; Subramanian, Aruna ; Tompkins, Lucy S. ; Grant, Philip ; Shafer, Robert W. ; Pinsky, Benjamin A.
• Description:
  We report persistent severe acute respiratory syndrome coronavirus 2 infection in a patient with HIV/AIDS; the virus developed spike N terminal domain and receptor binding domain neutralization resistance mutations. Our findings suggest that immunocompromised patients can harbor emerging variants of severe acute respiratory syndrome coronavirus 2.
• Subjects:
  Acquired Immunodeficiency Syndrome Coronavirus Infections Covid-19 Humans Mutation Protein Binding Sars-Cov-2 Spike Glycoprotein, Coronavirus
• Source:
  Emerg Infect Dis. 27(10):2720-2723
• Pubmed ID:
  34296992
• Pubmed Central ID:
  PMC8462335
• Document Type:
  Journal Article
• Place as Subject:
  California ; United States
• Location:
  North America
• Volume:
  27
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:59ac58c697f5d8a19290da1b870279df4d2d06d776e0d831c3e56ac2211fed20
• Download URL:
  https://stacks.cdc.gov/view/cdc/110450/cdc_110450_DS1.pdf
• File Type:
  [PDF - 834.69 KB ]