Genomic Evolution of SARS-CoV-2 Virus in Immunocompromised Patient, Ireland

Lynch, Maureen; Macori, Guerrino; Fanning, Séamus; O’Regan, Edel; Hunt, Eoin; O’Callaghan, Dermot; McCullagh, Brian; Jennings, Cormac; Fortune, Anne

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Genomic Evolution of SARS-CoV-2 Virus in Immunocompromised Patient, Ireland

Supporting Files Public Domain

Sep 2021
By Lynch, Maureen ; Macori, Guerrino ; Fanning, Séamus ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Lynch, Maureen ; Macori, Guerrino ; Fanning, Séamus ; O’Regan, Edel ; Hunt, Eoin ; O’Callaghan, Dermot ; McCullagh, Brian ; Jennings, Cormac ; Fortune, Anne
Description:

We examined virus genomic evolution in an immunocompromised patient with prolonged severe acute respiratory syndrome coronavirus 2 infection. Genomic sequencing revealed genetic variation during infection: 3 intrahost mutations and possible superinfection with a second strain of the virus. Prolonged infection in immunocompromised patients may lead to emergence of new virus variants.
Subjects:

Coronavirus Infections Covid-19 Evolution, Molecular Genomics Humans Immunocompromised Host Sars-Cov-2
Source:

Emerg Infect Dis. 27(9):2499-2501
Pubmed ID:

34161223
Pubmed Central ID:

PMC8386806
Document Type:

Journal Article
Place as Subject:

Ireland
Location:

Europe
Volume:

27
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:f471a981a46243c4d7ee45026fc5cab36f48c2b00b3d022d139c6cd559414b70
Download URL:

https://stacks.cdc.gov/view/cdc/109725/cdc_109725_DS1.pdf
File Type:

[PDF - 858.07 KB ]

File Language:

English

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