Risk Factors for Pediatric Invasive Group A Streptococcal Disease

Factor, Stephanie H.; Levine, Orin S.; Harrison, Lee H.; Farley, Monica M.; McGeer, Allison; Skoff, Tami; Wright, Carolyn; Schwartz, Benjamin; Schuchat, Anne

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Risk Factors for Pediatric Invasive Group A Streptococcal Disease

Jul 2005
By Factor, Stephanie H. ; Levine, Orin S. ; Harrison, Lee H. ; ...
Source: Emerg Infect Dis. 11(7):1062-1066.

[PDF-80.02 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Factor, Stephanie H. ; Levine, Orin S. ; Harrison, Lee H. ; Farley, Monica M. ; McGeer, Allison ; ... More +

Factor, Stephanie H. ; Levine, Orin S. ; Harrison, Lee H. ; Farley, Monica M. ; McGeer, Allison ; Skoff, Tami ; Wright, Carolyn ; Schwartz, Benjamin ; Schuchat, Anne Less -
Description:

Invasive group A Streptococcus (GAS) infections can be fatal and can occur in healthy children. A case-control study identified factors associated with pediatric disease. Case-patients were identified when Streptococcus pyogenes was isolated from a normally sterile site, and matched controls (>or=2) were identified by using sequential-digit dialing. All participants were noninstitutionalized surveillance-area residents <18 years of age. Conditional regression identified factors associated with invasive disease: other children living in the home (odds ratio [OR]=16.85, p=0.0002) and new use of nonsteroidal anti-inflammatory drugs (OR=10.64, p=0.005) were associated with increased risk. More rooms in the home (OR=0.67, p=0.03) and household member(s) with runny nose (OR=0.09, p=0.002) were associated with decreased risk. Among children, household-level characteristics that influence exposure to GAS most affect development of invasive disease.
Subjects:

[+]

Adolescent Case-Control Studies Child Child, Preschool Female Humans Infant Infant, Newborn Male Odds Ratio Research Risk Factors Socioeconomic Factors Streptococcal Infections
Source:

Emerg Infect Dis. 11(7):1062-1066.
Pubmed ID:

16022781
Pubmed Central ID:

PMC3371775
Document Type:

Journal Article
Volume:

11
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:42f7c9f33895c3abc888bf4fa03b8a5c7adb038c0272e827d5d8fc49ee44f49c
Download URL:

https://stacks.cdc.gov/view/cdc/10797/cdc_10797_DS1.pdf
File Type:

04-0900.nxml

bin

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