Monitoring Antimicrobial Use and Resistance: Comparison with a National Benchmark on Reducing Vancomycin Use and Vancomycin-Resistant Enterococci

Fridkin, Scott K.; Lawton, Rachel; Edwards, Jonathan R.; Tenover, Fred C.; McGowan, John E.; Gaynes, Robert P.

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Monitoring Antimicrobial Use and Resistance: Comparison with a National Benchmark on Reducing Vancomycin Use and Vancomycin-Resistant Enterococci

Published Date:

Jul 2002

Source:

Emerg Infect Dis. 8(7):702-707.

[PDF-249.44 KB]

Details:

Personal Authors:

Fridkin, Scott K. ; Lawton, Rachel ; Edwards, Jonathan R. ; Tenover, Fred C. ; McGowan, John E. ; ... More ▼

Corporate Authors:

Intensive Care Antimicrobial Resistance Epidemiology (ICARE) Project, and the National Nosocomial Infections Surveillance (NNIS) System Hospitals

Keywords:

[+]

Description:

To determine if local monitoring data on vancomycin use directed quality improvement and decreased vancomycin use or vancomycin-resistant enterococci (VRE), we analyzed data from 50 intensive-care units (ICUs) at 20 U.S. hospitals reporting data on antimicrobial-resistant organisms and antimicrobial agent use. We compared local data with national benchmark data (aggregated from all study hospitals). After data were adjusted for changes in prevalence of methicillin-resistant Staphylococcus aureus, changes in specific prescriber practice at ICUs were associated with significant decreases in vancomycin use (mean decrease -48 defined daily doses per 1,000 patient days, p<0.001). These ICUs also reported significant decreases in VRE prevalence compared with those not using unit-specific changes in practice (mean decrease of 7.5% compared with mean increase of 5.7%, p<0.001). In this study, practice changes focused towards specific ICUs were associated with decreases in ICU vancomycin use and VRE prevalence.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases
CDC Public Access

Supporting Files:

	01-0465-F1.gif	image/gif
	01-0465-F1.jpg	image/jpeg
	01-0465-F2.gif	image/gif
	01-0465-F2.jpg	image/jpeg
	01-0465_FinalR.nxml	text/plain
	license.txt	text/plain

No Related Documents.

You May Also Like:

Vancomycin and Home Health Care

Personal Author:

Fraser, Thomas G.; Stosor, Valentina; Wang, Qiong; Allen, Anne; Zembower, Teresa R.;

Published:

Oct 2005

Source:

Emerg Infect Dis. 11(10):1558-1564.

Description:

The Hospital Infection Control Practices Advisory Committee published guidelines for prudent use of vancomycin to combat increasing resistance to antimicrobial drugs. Studies examining compliance with these guidelines primarily involve hospitalized p...

File Type:

[PDF - 152.14 KB]
Controlling antimicrobial resistance in hospitals: infection control and use of antibiotics.

Personal Author:

Weinstein, R. A.

Published:

2001 Mar-Apr

Source:

Emerg Infect Dis. 7(2):188-192.

Description:

Antimicrobial-drug resistance in hospitals is driven by failures of hospital hygiene, selective pressures created by overuse of antibiotics, and mobile genetic elements that can encode bacterial resistance mechanisms. Attention to hand hygiene is con...

File Type:

[PDF - 82.30 KB]
Recommendations for preventing the spread of vancomycin resistance; recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC)

Personal Author:

Favero, Martin S.; Gaynes, Robert P.; Jarvis, William R. (William Robert), 1948-; Shaw, J.; Tablan, Ofelia C.; Tenover, Fred C.;

Corporate Author:

Hospital Infection Control Practices Advisory Committee (U.S.). Centers for Disease Control and Prevention (CDC). National Center for Infectious Diseases (U.S.), Hospital Infections Program..

Published:

September 22, 1995

Series:

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 44, no. RR-12
HHS Publication ; no. (CDC) 95-8017

Description:

Since 1989, a rapid increase in the incidence of infection and colonization with vancomycin-resistant enterococci (VRE) has been reported by U.S. hospitals. This increase poses important problems, including a) the lack of available antimicrobial ther...

Status:

retired

File Type:

[PDF - 212.01 KB]
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections, March 5-9, 2000, Atlanta, Georgia

Corporate Author:

Association for Professionals in Infection Control and Epidemiology. Centers for Disease Control and Prevention (U.S.). National Foundation for Infectious Diseases (U.S.). Society for Healthcare Epidemiology of America.

Conference Author:

International Conference on Nosocomial and Healthcare-Associated Infections 2000 : Atlanta, GA); International Conference on Nosocomial Infections 1990 : Atlanta, GA);

Published:

March-April 2001

Series:

Emerging infectious diseases ; v. 7, no. 2

Description:

Conference organized and sponsored by the Centers for Disease Control and Prevention, the Association for Professionals in Infection Control, the Society for Healthcare Epidemiology of America, and the National Foundation for Infectious Diseases. : P...

File Type:

[PDF - 2.62 MB]
A Public health action plan to combat antimicrobial resistance; 2012 update

Corporate Author:

United States, Interagency Task Force on Antimicrobial Resistance.. Centers for Disease Control and Prevention (U.S.). National Institutes of Health (U.S.). United States, Food and Drug Administration..

Published:

2012

Description:

In 2001, the Task Force developed an initial Action Plan, outlining specific issues, goals, and actions important for addressing the problem of AR. This document, entitled A Public Health Action Plan to Combat Antimicrobial Resistance, Part I: Domest...

File Type:

[PDF - 2.45 MB]