Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Fridkin, Scott K. ; Lawton, Rachel ; Edwards, Jonathan R. ; Tenover, Fred C. ; McGowan, John E. ; ... More +
Fridkin, Scott K. ; Lawton, Rachel ; Edwards, Jonathan R. ; Tenover, Fred C. ; McGowan, John E. ; Gaynes, Robert P. ; Less -
Corporate Authors:
Intensive Care Antimicrobial Resistance Epidemiology (ICARE) Project, and the National Nosocomial Infections Surveillance (NNIS) System Hospitals ;
Description:
To determine if local monitoring data on vancomycin use directed quality improvement and decreased vancomycin use or vancomycin-resistant enterococci (VRE), we analyzed data from 50 intensive-care units (ICUs) at 20 U.S. hospitals reporting data on antimicrobial-resistant organisms and antimicrobial agent use. We compared local data with national benchmark data (aggregated from all study hospitals). After data were adjusted for changes in prevalence of methicillin-resistant Staphylococcus aureus, changes in specific prescriber practice at ICUs were associated with significant decreases in vancomycin use (mean decrease -48 defined daily doses per 1,000 patient days, p<0.001). These ICUs also reported significant decreases in VRE prevalence compared with those not using unit-specific changes in practice (mean decrease of 7.5% compared with mean increase of 5.7%, p<0.001). In this study, practice changes focused towards specific ICUs were associated with decreases in ICU vancomycin use and VRE prevalence.
Subject:
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Anti-Bacterial Agents
Benchmarking
Cross Infection
Drug Resistance, Multiple, Bacterial
Enterococcus
Gram-Positive Bacterial Infections
Humans
Infection Control
Intensive Care Units
Methicillin
Quality Assurance, Health Care
Research
Risk Factors
Vancomycin
Vancomycin Resistance

Source:
Emerg Infect Dis. 8(7):702-707. ;
Document Type:
Journal Article ;
Place as Subject:
United States ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:0459bb4d250d565f76bc180b76d76cd466a9a7964fb7aad1705b9d9738613d3c
File Type:

Supporting Files

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