i
AIDS : the early years and CDC's response
-
October 7, 2011
-
Source: MMWR Suppl. 2011 Oct 7;60(4):64-9.
Details:
-
Personal Author:
-
Corporate Authors:
-
Description:The MMWR description of five cases of Pneumocystis carinii pneumonia (PCP) among homosexual men in Los Angeles was the first published report about an illness that would become known as acquired immunodeficiency syndrome (AIDS) (1). Appearing 4 months before the first peer-reviewed article (2), the timeliness of the report can be credited to the astute clinical skills and public health sensitivity of Dr. Michael Gottlieb and his colleagues at the University of California, Los Angeles, School of Medicine and Cedars-Sinai Hospital, who worked closely with Dr. Wayne Shandera, the CDC Epidemic Intelligence Service (EIS) officer assigned to the Los Angeles County Department of Health Services.
The Parasitic Diseases Division of CDC's Center for Infectious Diseases already had become concerned about other reports of unusual cases of PCP. The Division housed the Parasitic Disease Drug Service, which administered the distribution of pentamidine isethionate for PCP treatment. Because PCP was rare and pentamidine was not yet licensed in the United States, it was available only from CDC. A review of requests for pentamidine had documented that PCP in the United States was almost exclusively limited to patients with cancer or other conditions or treatments known to be associated with severe immunosuppression (3). Recent requests for this drug from physicians in New York and California to treat PCP in patients with no known cause of immunodeficiency had sparked the attention of Division staff.
su6004a11.htm?s_cid=su6004a11_w
-
Subjects:
-
Source:
-
Series:
-
Document Type:
-
Name as Subject:
-
Genre:
-
Place as Subject:
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: