Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nonaka, Carolina K. V. ; Franco, Marília Miranda ; Gräf, Tiago ; de Lorenzo Barcia, Camila Araújo ; de Ávila Mendonça, Renata Naves ; de Sousa, Karoline Almeida Felix ; Neiva, Leila M. C. ; Fosenca, Vagner ; Mendes, Ana V. A. ; de Aguiar, Renato Santana ; Giovanetti, Marta ; de Freitas Souza, Bruno Solano
• Description:
  Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies.
• Subjects:
  Antibodies, Neutralizing Coronavirus Infections Covid-19 Genomics Humans Mutation Reinfection Sars-Cov-2 Spike Glycoprotein, Coronavirus
• Source:
  Emerg Infect Dis. 27(5):1522-1524
• Pubmed ID:
  33605869
• Pubmed Central ID:
  PMC8084516
• Document Type:
  Journal Article
• Genre:
  Letter
• Place as Subject:
  Brazil
• Volume:
  27
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:aa35e975cfd56b93cc92ef7532d2e8702a64c7a6e01ad2f60610bdf4eea5c7d2
• Download URL:
  https://stacks.cdc.gov/view/cdc/106042/cdc_106042_DS1.pdf
• File Type:
  [PDF - 1.29 MB ]