Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Ott, Isabel M. ; Strine, Madison S. ; Watkins, Anne E. ; Boot, Maikel ; Kalinich, Chaney C. ; Harden, Christina A. ; Vogels, Chantal B.F. ; Casanovas-Massana, Arnau ; Moore, Adam J. ; Muenker, M. Catherine ; Nakahata, Maura ; Tokuyama, Maria ; Nelson, Allison ; Fournier, John ; Bermejo, Santos ; Campbell, Melissa ; Datta, Rupak ; Dela Cruz, Charles S. ; Farhadian, Shelli F. ; Ko, Albert I. ; Iwasaki, Akiko ; Grubaugh, Nathan D. ; Wilen, Craig B. ; Wyllie, Anne L.
• Corporate Authors:
  Yale IMPACT Research team
• Description:
  The expense of saliva collection devices designed to stabilize severe acute respiratory syndrome coronavirus 2 RNA is prohibitive to mass testing. However, virus RNA in nonsupplemented saliva is stable for extended periods and at elevated temperatures. Simple plastic tubes for saliva collection will make large-scale testing and continued surveillance easier.
• Subjects:
  Capacity Building Coronavirus Infections Covid-19 Nucleic Acid Testing Humans Reproducibility Of Results Resource Allocation Rna, Viral Rna Stability Saliva Sars-Cov-2 Specimen Handling

  More +
• Source:
  Emerg Infect Dis. 27(4):1146-1150
• Pubmed ID:
  33754989
• Pubmed Central ID:
  PMC8007305
• Document Type:
  Journal Article
• Volume:
  27
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:3181b82303f641676e11fff485000883fc58f7375a926a3f2a360fe17cf41a69
• Download URL:
  https://stacks.cdc.gov/view/cdc/104872/cdc_104872_DS1.pdf
• File Type:
  [PDF - 1.35 MB ]