The Effect of Body Composition and Energy Expenditure on Permethrin Biomarker Concentrations among US Army National Guard Members

Details

• Alternative Title:
  J Occup Environ Med
• Personal Author:
  Scarpaci, Matthew M. ; Haven, Caitlin C. ; Maule, Alexis L. ; Heaton, Kristin J. ; Taylor, Kathryn M. ; Rood, Jennifer ; Ospina, Maria ; Calafat, Antonia M ; Proctor, Susan P.
• Description:
  Objective:
  
  To examine relationships between percent body fat (%BF) and total energy expenditure (TEE) on permethrin exposure among Army National Guard (ARNG) Soldiers wearing permethrin-treated uniforms.
  
  Methods:
  
  ARNG members (n=47) participated in a nine-day study. Repeated body composition (height, weight, %BF) measurements and daily urine samples, analyzed for permethrin and N,N-diethyl-meta-toluamide (DEET) metabolites, were collected. TEE was determined via doubly labeled water protocol. Linear mixed and regression models were used for analyses.
  
  Results:
  
  Neither %BF nor TEE were significantly associated with permethrin or DEET biomarkers. However, a significant interaction effect (F=10.76; p=0.0027) between laundering history and %BF was observed; 10% higher %BF was significantly associated with 25% higher permethrin biomarker concentrations among those wearing uniforms washed ≤25 (compared to >25) times.
  
  Conclusions:
  
  Uniform laundering history significantly affects the association between %BF and permethrin-treated uniform exposure.
  
  
• Subjects:
  Article Biomarkers Body Composition Energy Expenditure Military Occupational Permethrin
• Source:
  J Occup Environ Med. 62(3):210-216
• Pubmed ID:
  31895734
• Pubmed Central ID:
  PMC7953413
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  62
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:bf28c4a6b69917b4bb79171d164fa188a1e8ba87958b039c6d84fd35fec5e152
• Download URL:
  https://stacks.cdc.gov/view/cdc/104105/cdc_104105_DS1.pdf
• File Type:
  [PDF - 617.81 KB ]