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The Effect of Body Composition and Energy Expenditure on Permethrin Biomarker Concentrations among US Army National Guard Members
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March 2020
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Source: J Occup Environ Med. 62(3):210-216
Details:
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Alternative Title:J Occup Environ Med
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Personal Author:
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Description:Objective:
To examine relationships between percent body fat (%BF) and total energy expenditure (TEE) on permethrin exposure among Army National Guard (ARNG) Soldiers wearing permethrin-treated uniforms.
Methods:
ARNG members (n=47) participated in a nine-day study. Repeated body composition (height, weight, %BF) measurements and daily urine samples, analyzed for permethrin and N,N-diethyl-meta-toluamide (DEET) metabolites, were collected. TEE was determined via doubly labeled water protocol. Linear mixed and regression models were used for analyses.
Results:
Neither %BF nor TEE were significantly associated with permethrin or DEET biomarkers. However, a significant interaction effect (F=10.76; p=0.0027) between laundering history and %BF was observed; 10% higher %BF was significantly associated with 25% higher permethrin biomarker concentrations among those wearing uniforms washed ≤25 (compared to >25) times.
Conclusions:
Uniform laundering history significantly affects the association between %BF and permethrin-treated uniform exposure.
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Source:
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Pubmed ID:31895734
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Pubmed Central ID:PMC7953413
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Funding:
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Volume:62
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Issue:3
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