Permethrin exposure from wearing fabric-treated military uniforms in high heat conditions under varying wear-time scenarios

Details

• Alternative Title:
  J Expo Sci Environ Epidemiol
• Personal Author:
  Proctor, Susan P. ; Maule, Alexis L. ; Heaton, Kristin J. ; Cadarette, Bruce S. ; Guerriere, Katelyn I. ; Haven, Caitlin C. ; Taylor, Kathryn M. ; Scarpaci, Matthew M. ; Ospina, Maria ; Calafat, Antonia M.
• Description:
  This study examined the effect of high-temperature conditions and uniform wear time durations (expeditionary, 33 h continuous wear; garrison, 3 days, 8 h/day wear) on permethrin exposure, assessed by urinary permethrin biomarkers, from wearing post-tailored, factory-treated military uniforms. Four group study sessions took place over separate 11-day periods, involving 33 male Soldiers. Group 1 (n = 10) and Group 2 (n = 8) participants wore a study-issued permethrin-treated Army uniform under high heat environment (35 °C, 40% relative humidity (rh)) and expeditionary and garrison wear-time conditions, respectively. For comparison, Group 3 (n = 7) and Group 4 (n = 8) participants wore study-issued permethrin-treated uniforms in cooler ambient conditions under operational and garrison wear-time conditions, respectively. Urinary biomarkers of permethrin (3-phenoxybenzoic acid, and the sum of cis- and trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid) were significantly higher under high temperature compared to ambient conditions, regardless of wear-time situations (Group 1 vs. Group 3; Group 2 vs. Group 4; p < 0.001, for both). Under high-temperature conditions, expeditionary (continuous) compared to garrison wear-time resulted in significantly (p < 0.001) higher urinary biomarker concentrations (Group 1 vs. Group 2). Differences related to wear-time under the ambient conditions (Group 3 vs. Group 4) were not statistically significant. Findings suggest that wearing permethrin-treated clothing in heat conditions results in higher internal dose of permethrin above that observed under ambient conditions.
• Subjects:
  Adult Benzoates Biomarkers Clothing Hot Temperature Humans Insecticides Male Military Personnel Permethrin Time Factors

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• Keywords:
  Absorbed Dose Heat Military Pesticides Urinary Biomarkers
• Source:
  J Expo Sci Environ Epidemiol. 30(3):525-536
• Pubmed ID:
  30728486
• Pubmed Central ID:
  PMC7971189
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  30
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:2ef31c8c0eddddbe59f9037810087ab17554b7a23213811c449085ac1f424fe4
• Download URL:
  https://stacks.cdc.gov/view/cdc/104327/cdc_104327_DS1.pdf
• File Type:
  [PDF - 617.39 KB ]