Decline of Tuberculosis Burden in Vietnam Measured by Consecutive National Surveys, 2007–2017

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nguyen, Hai Viet ; Nguyen, Hoa Binh ; Nguyen, Nhung Viet ; Cobelens, Frank ; Finlay, Alyssa ; Dao, Cu Huy ; Mirtskhulava, Veriko ; Glaziou, Philippe ; Pham, Huyen T.T. ; de Haas, Petra ; Tiemersma, Edine
• Description:
  Vietnam, a high tuberculosis (TB) burden country, conducted national TB prevalence surveys in 2007 and 2017. In both surveys participants were screened by using a questionnaire and chest radiograph; sputum samples were then collected to test for Mycobacterium tuberculosis by smear microscopy and Löwenstein-Jensen culture. Culture-positive, smear-positive, and smear-negative TB cases were defined by laboratory results, and the prevalence of tuberculosis was compared between the 2 surveys. The results showed prevalence of culture-positive TB decreased by 37% (95% CI 11.5%-55.4%), from 199 (95% CI 160-248) cases/100,000 adults in 2007 to 125 (95% CI 98-159) cases/100,000 adults in 2017. Prevalence of smear-positive TB dropped by 53% (95% CI 27.0%-69.7%), from 99 (95% CI 78-125) cases/100,000 adults to 46 (95% CI 32-68) cases/100,000 adults; smear-negative TB showed no substantial decrease. Replacing microscopy with molecular methods for primary diagnostics might enhance diagnosis of pulmonary TB cases and further lower TB burden.
• Subjects:
  Adult Diagnostic Tests, Routine Humans Mycobacterium Tuberculosis Sensitivity And Specificity Sputum Tuberculosis Tuberculosis, Pulmonary
• Source:
  Emerg Infect Dis. 27(3):872-879
• Pubmed ID:
  33622491
• Pubmed Central ID:
  PMC7920672
• Document Type:
  Journal Article
• Place as Subject:
  Vietnam
• Volume:
  27
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:eeb0c3efb8fef0b7208ee74699b9b73fcc4a1bb853b1a3a0491cecffa0790e1e
• Download URL:
  https://stacks.cdc.gov/view/cdc/104052/cdc_104052_DS1.pdf
• File Type:
  [PDF - 2.17 MB ]