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- :Konermann, Silvana ;Brigham, Mark D.Dec 10 2014 | Nature. 517(7536):583-588.:Systematic interrogation of gene function requires the ability to perturb gene expression in a robust and generalizable manner. Here we describe struc...
- :Ray, M. E. ;Guan, X. Y.Jul 1994 | Br J Cancer. 70(1):85-90.:Images
- :Shalem, Ophir ;Sanjana, Neville E.Dec 12 2013 | Science. 343(6166):84-87.:The simplicity of programming the CRISPR (clustered regularly interspaced short palindromic repeats)-associated nuclease Cas9 to modify specific genom...
- :Zheng, Guanqun ;Qin, Yidan9 2015 | Nat Methods. 12(9):835-837:Despite its biological importance, tRNA has not been adequately sequenced by standard methods because of its abundant post-transcriptional modificatio...
- :Shalem, Ophir ;Sanjana, Neville E.5 2015 | Nat Rev Genet. 2015; 16(5):299-311:Forward genetic screens are powerful tools for the discovery and functional annotation of genetic elements. Recently, the RNA-guided CRISPR (clustered...
- :Marine, Rachel L. ;Magaña, Laura C.6 2020 | J Virol Methods. 280:113865:Next-generation sequencing is a powerful tool for virological surveillance. While Illumina® and Ion Torrent® sequencing platforms are used extensive...
- :Balasubramaniam, Vinod R. M. T. ;Hong Wai, ThamSep 20 2013 | PLoS One. 2013; 8(9).:We constructed a novel chicken (Gallus gallus) lung cDNA library fused inside yeast acting domain vector (pGADT7). Using yeast two-hybrid screening wi...
- :Beliveau, Brian J. ;Boettiger, Alistair N.05 12 2015 | Nat Commun. 6:7147:Fluorescence in situ hybridization (FISH) is a powerful single-cell technique for studying nuclear structure and organization. Here we report two adva...
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