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Showing 47061 - 47080 of 82803 results
  • Job Stages of Entry Mastery and Disengagement Among Nurses
    Job Stages of Entry, Mastery, and Disengagement Among Nurses
    McNeese-Smith DK
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Objectives: To examine the phenomenon of job stages, particularly entry, mastery, and disengagement; to identify predictors of each stage; and to determine when disengagement occurs among nurses. Summary Background Data: Job or career stages have been conceptualized as an aspect of growth and development and also career growth and change. Graham id ...
  • Characterization and Variability of Endotoxin and 3Hydroxy Fatty Acids in an Office Building During a Particle Intervention Study
    Characterization and Variability of Endotoxin and 3-Hydroxy Fatty Acids in an Office Building During a Particle Intervention Study
    Fisk WJ ;
    Hines CJ
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Air and dust samples were collected on two floors of an office building during a double-blind particle intervention study to examine spatial and temporal variability of airborne endotoxin over a period of weeks, and to characterize endotoxin activity and lipopolysaccharide (LPS) content in carpet and chair dust. Air samples were collected on multip ...
    Public Domain
  • Mist Control at a Machining Center Part 1 Mist Characterization
    Mist Control at a Machining Center, Part 1: Mist Characterization
    Deye GJ ;
    Heitbrink, William A.
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    At a machining center used to produce transmission parts, aerosol instrumentation was used to quantitatively study mist generation and to evaluate the performance of an air cleaner for controlling the mist. This machining center drilled and tapped holes at rotational speeds of 1000 to 3000 rpm. During most machining operations, the metalworking flu ...
    Public Domain
  • Vitamin E Deficiency Increases Susceptibility of the BALBC Mouse to MDMAInduced Dopaminergic Neurotoxicity
    Vitamin E Deficiency Increases Susceptibility of the BALB/C Mouse to MDMA-Induced Dopaminergic Neurotoxicity
    Johnson, Elizabeth A. ;
    Kisin E
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    The mechanism of 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity has been hypothesized to involve the formation of toxic free radical species. Since Vitamin E is a potent radical scavenger, we tested whether Vitamin E deficiency affects susceptibility to MDMA-induced dopaminergic neurotoxicity. Male BALB/c mice (3-4 weeks old) were k ...
    Public Domain
  • Ovalbumin Aeroallergen ExposureResponse in Brown Norway Rats
    Ovalbumin Aeroallergen Exposure-Response in Brown Norway Rats
    Al-Humadi NH ;
    Fedan, Jeffery S.
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    A major route of exposure to allergens is through the respiratory tract. Comparatively few animal studies have used aerosolized high-molecular-weight allergens for sensitization, and in these studies, proper characterization of the aeroallergen exposure was usually missing. The purpose of this study was to profile the exposure-response relationship ...
    Public Domain
  • Complications in Interpretation of Diagnostic Tests for Latex Allergy
    Complications in Interpretation of Diagnostic Tests for Latex Allergy
    Biagini, Raymond E.
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    The diagnosis of natural rubber latex allergy begins with a clinical history and often involves a confirmatory test. While the puncture skin test (PST) has been regarded as a primary confirmatory test for the assessment of patients for IgE-mediated disease, the absence of an FDA-licensed Hevea brasiliensis latex extract in the USA has restricted it ...
    Public Domain
  • Health Hazard Evaluation Report HETA 9801732782 Colorado Department of Public Health and Environment Colorado
    Health Hazard Evaluation Report: HETA 98-0173-2782: Colorado Department of Public Health and Environment, Colorado
    McCammon, Jane B. ;
    McKenzie, Lyle E.
    2000/03/01 | Health Hazard Evaluation Reports (HHE)
    On March 30, 1998, the Colorado Department of Public Health and Environment (CDPHE) requested assistance in a project to be conducted in cooperation with the US Department of Agriculture Forest Service (USFS) and the Department of Interior Bureau of Land Management (BLM) personnel. The goal of the CDPHE project was to field-test implementation of a ...
    Public Domain
  • A New VideoSynchronized Multichannel Biomedical Data Acquisition System
    A New Video-Synchronized Multichannel Biomedical Data Acquisition System
    Hsiao H ;
    Powers JR
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    This data acquisition system records video frames onto a video tape, and simultaneously acquires biomedical data along with video time codes onto a computer hard disk to achieve a 30-min video-synchronized data recording with a summed data rate of 2.16 Mbit/s. A time-code-bridge-file created during acquisition matches each video frame-start with th ...
  • Exposure to Silica Activates Macrophages and Increases the Pulmonary Clearance of Listeria monocytogenes in Rats
    Exposure to Silica Activates Macrophages and Increases the Pulmonary Clearance of Listeria monocytogenes in Rats
    Antonini JM ;
    Barger MW
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Alveolar macrophages (AM) play a crucial role in protecting the lungs from infectious agents. In this study, we evaluated the effect of silica on macrophage function using a rat Listeria monocytogenes (LM) infection model. Male Sprague-Dawley rats were instilled intratracheally with saline or silica (20 mg/rat). Thirty-five days later, the rats wer ...
    Public Domain
  • Postexposure Prophylaxis for HIV Exposed Health Care Workers
    Postexposure Prophylaxis for HIV Exposed Health Care Workers
    Lusk SL ;
    Robbins WA
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    A significant number of workers (more than 8 million) are employed in hospitals and other health care settings. The National Institute for Occupational Safety and Health (NIOSH) (1999) estimates 600,000 to 800,000 needlestick injuries occur each year in the United States. Approximately half of these are unreported. Data from a University of Virgini ...
  • Uranium Mining and Lung Cancer Among Navajo Men in New Mexico and Arizona 1969 to 1993
    Uranium Mining and Lung Cancer Among Navajo Men in New Mexico and Arizona, 1969 to 1993
    Gilliland FD ;
    Hunt WC
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Navajo men who were underground miners have excess risk of lung cancer. To further characterize the long-term consequences of uranium mining in this high-risk population, we examined lung cancer incidence among Navajo men residing in New Mexico and Arizona from 1969 to 1993 and conducted a population-based case-control study to estimate the risk of ...
  • Comparison of Pulmonary Response to Inhaled and Intratracheally Instilled Diesel Exhaust Particulate
    Comparison of Pulmonary Response to Inhaled and Intratracheally Instilled Diesel Exhaust Particulate
    Al-Humadi NH ;
    Siegel, Paul D.
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Diesel exhaust particulate (DEP) is a complex mixture of polyaromatic hydrocarbons, ash, transition metals, and carbon core. Exposure levels of DEP up to 2 mwm3 has been documented in underground mines, railroad, construction, and auto repair industries. Such exposures have been associated with pulmonary inflammation, fibrosis, lung cancer, increas ...
    Public Domain
  • Mechanism of Methylene Diphenyl Diisocyanate Glutathione Conjugate Micronuclei Induction Distinguishable from That of Methylenedinaline
    Mechanism of Methylene Diphenyl Diisocyanate Glutathione Conjugate Micronuclei Induction Distinguishable from That of Methylenedinaline
    Siegel, Paul D. ;
    Zhong BZ
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Methlyene di-phenyl diisocyanate (MDI) is widely used in the production of polyurethane products, such as wood binders and foams. Diisocyanates are very reactive compounds that can undergo nonenzymatic hydrolysis to form methylenedianiline (MDA), or react under physiological conditions with primary amines to form ureas and/or with thiols to form la ...
    Public Domain
  • Respiratory Protective Equipment
    Respiratory Protective Equipment
    Myers WR
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    The respirator is historically one of the oldest types of equipment used for personal protection in the occupational setting. It is uncertain when the use of primitive forms of respiratory protection began. However, Pliny the Elder recorded the first known use of such a device early in the 1st century ad. Although respirators have been used for alm ...
  • The Role of Airway Neurons in O3Induced Airway HyperResponsiveness AHR in Ferret Trachea
    The Role of Airway Neurons in O3-Induced Airway Hyper-Responsiveness (AHR) in Ferret Trachea
    Dey RD ;
    Fedan, Jeffery S.
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Exposure to O3 is frequently associated with AHR. Release of substance P (SP) from sensory C-fibers may contribute to AHR, but SP levels are increased in intrinsic airway ganglia after O3 exposure. The aim of this study is to examine the role of intrinsic neurons in AHR. Ferrets were exposed to 2ppm O3 or air for 1 h. Tracheas were removed and main ...
    Public Domain
  • Creep Along Weak Planes in Roof and How It Affects Stability
    Creep Along Weak Planes in Roof and How It Affects Stability
    03/01/2000 | NIOSH
    A NIOSH study of the time-dependent response of rock stressed along weakness planes with the objective to improve mine safety by reducing the number of roof falls that cause injuries and fatalities to miners.
    Public Domain
  • InDepth Survey Report Field Evaluation of Roadtec Engineering Controls Designed to Reduce Occupational Exposures During Asphalt Paving Operations Manufacturer Roadtec Paving Products Paving Contractor CW Matthews Contracting Company Paving Location Calhoun Georgia
    In-Depth Survey Report: Field Evaluation of Roadtec Engineering Controls Designed to Reduce Occupational Exposures During Asphalt Paving Operations: Manufacturer Roadtec Paving Products: Paving Contractor C.W. Matthews Contracting Company: Paving Location Calhoun, Georgia
    Mead, Kenneth R. ;
    Mickelsen, Ronald L.
    2000/03/01 | Engineering and Physical Hazards Survey Reports
    On November 4-7, 1996, researchers from the National Institute for Occupational Safety and Health (NIOSH) evaluated a first-generation engineering control designed to capture and remove fugitive asphalt emissions during asphalt paving. The Roadtec engineering control evaluation was completed as part of a Department of Transportation (DOT) project t ...
    Public Domain
  • Application of a Human Skin Tissue Culture Model in Dermal Absorption Studies of 33 44TetrachlorobiphenylTCB
    Application of a Human Skin Tissue Culture Model in Dermal Absorption Studies of 3,3′, 4,4′-Tetrachlorobiphenyl-(TCB)
    Qiao GL ;
    Riviere JE
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    TCB, one of the dioxin-like PCBs. demands much research and regulatory attention. To evaluate an in vitro generated human skin tissue culture model, cutaneous disposition of TCB under different exposure scenarios was investigated. Occlusive or non-occlusive doses of 14C- TCB were applied at 4 or 40 ug/cm2 in different vehicles including acetone, me ...
    Public Domain
  • The Influence of CoPollutants on the Toxicity of Airborne Particulate Matter
    The Influence of Co-Pollutants on the Toxicity of Airborne Particulate Matter
    Madden NC ;
    Pinkerton KE
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Recent epidemiological reports have shown an association between ambient air particulate matter (PM) concentrations and human mortality and morbidity, such as increased hospitalizations. PM coexists in the ambient air with many other pollutants, and therefore complicates the assessment of the contribution of PM to the affected health endpoints. In ...
  • Skin Penetration by the Natural Rubber Latex Proteins Hevein and Rubber Elongation Factor
    Skin Penetration by the Natural Rubber Latex Proteins, Hevein, and Rubber Elongation Factor
    Alenius H ;
    Hayes BB
    2000/03/01 | National Institute for Occupational Safety and Health (NIOSH)
    Differences in IgE antibody patterns have been demonstrated in latex allergic individuals who have undergone multiple surgeries and those with limited surgical exposure to natural rubber latex (NRL). Adult health care workers show a higher prevalence of antibody towards hevein (Hev b 6.02) whereas children requiring multiple surgeries have shown a ...
    Public Domain
47061 - 47080 / 82803