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Showing 4181 - 4200 of 82972 results
  • Lung Toxicity and Gene Expression Changes in Response to Multiwalled Carbon Nanotubes Exposure in Rats
    Lung Toxicity and Gene Expression Changes in Response to Multiwalled Carbon Nanotubes Exposure in Rats
    Boots T ;
    Joseph P
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Carbon-based nanomaterials have many applications and, therefore, human exposure to them potentially resulting in adverse health effects should be anticipated. Determination of the molecular mechanisms underlying the toxicity induced by carbon nanotubes has merit in the prevention of the adverse health effects potentially resulting from their expos ...
    Public Domain
  • Effect of welding fume exposure on silicainduced pulmonary toxicity in rats
    Effect of welding fume exposure on silica-induced pulmonary toxicity in rats.
    Joseph P ;
    McKinney W
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Mixed exposures to silica and welding fume are common in certain occupations. It is currently undetermined what health burden workers exposed to both silica and welding fume experience. The objective of this study was to determine the effect of welding fume on the lung response to silica exposure. Male Fischer 344 rats were exposed to air or silica ...
    Public Domain
  • Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice
    Effect of inhalation exposure to cellulose nanocrystals on reproductive outcomes of male mice.
    Guppi S ;
    Gutkin D
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Crystalline nanocelluloses (CNC) have good electrical, optical, and mechanical properties which make them desirable for industrial applications. We investigated adverse reproductive outcomes due to inhalation exposure to CNC aerosol, generated from a bulk supply of wood pulp derived cellulose nanocrystals. C57BL6/J male mice were exposed to precise ...
    Public Domain
  • Model predictions of occupational exposures to diacetyl and 23pentanedione emitted from roasted whole bean and ground coffee influence of roast level and physical form on specific emission rates
    Model predictions of occupational exposures to diacetyl and 2,3-pentanedione emitted from roasted whole bean and ground coffee: influence of roast level and physical form on specific emission rates.
    Burns, Dru A. ;
    Fernandez E
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Roasted coffee emits hazardous volatile organic compounds including diacetyl and 2,3-pentanedione. Workers in non-flavored coffee roasting and packaging facilities might inhale diacetyl and 2,3-pentanedione from roasted coffee above occupational exposure limits depending on their work activities and proximity to the source of emissions. Objectives ...
    Public Domain
  • Toxicity of fluorinated and fluorinefree foams potential implications on firefighter renal health
    Toxicity of fluorinated and fluorine-free foams: potential implications on firefighter renal health.
    Beitel S ;
    Burgess J
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Military Specification aqueous film forming foams (AFFF)-typically comprised of complex mixtures of per- and polyfluorinated alkyl substances (PFAS), solvents, stabilizers, and wetting agents-are used to extinguish liquid fuel fires. Health concerns from use of AFFF have emerged because of studies documenting elevated PFAS serum levels in some fire ...
    Public Domain
  • Literature Review and Experimental Studies to Evaluate the Bioaccessibility and Dermal Penetration of Inorganic Pb Compounds for Occupational Risk Assessment
    Literature Review and Experimental Studies to Evaluate the Bioaccessibility and Dermal Penetration of Inorganic Pb Compounds for Occupational Risk Assessment
    Maier A ;
    Niemeier, R. Todd
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Evaluations were conducted to better understand the potential for dermal penetration of Pb compounds in workplace settings. This included 1) a rapid review of published data for estimation of key percutaneous absorption parameters (Kp, diffusion rates), 2) a dermal bioaccessibility study of 4 Pb compounds (Pb acetate (PbA), Pb Nitrate (PbN), Pb oxi ...
    Public Domain
  • CNCexposed paternal reproductive toxicity affects the placenta
    CNC-exposed paternal reproductive toxicity affects the placenta.
    Campagnolo L ;
    Kagan VE
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Exposure of mice to nanocellulose crystals (CNC) is known to affect male reproductivity caused by alterations in sperm properties such as concentration, motility, morphology and DNA integrity. Mechanisms driving these malfunctioning reproductive responses to CNC exposure are unclear. Published results support the idea that epigenetic changes contri ...
    Public Domain
  • Neoplastic Transformation and Changes in Transcriptome Induced by RiebeckiteTremolite Asbestiform and Nonasbestiform Elongate Mineral Particles in Human Mesothelial Cells
    Neoplastic Transformation and Changes in Transcriptome Induced by Riebeckite/Tremolite Asbestiform and Nonasbestiform Elongate Mineral Particles in Human Mesothelial Cells
    Guppi S ;
    Kagan VE
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Inhalation of respirable amphibole asbestiform elongate mineral particles (EMPs) can cause asbestosis, lung cancer as well as pleural and peritoneal mesothelioma. Amphiboles can also occur in a non-asbestiform habit that can be mechanically broken into so-called cleavage fragments (CF) which can meet the mineralogical/ regulatory criteria for fiber ...
    Public Domain
  • Keratinocytes and melanocytes have distinct and shared responses to metalbased nanocatalysts and UVB
    Keratinocytes and melanocytes have distinct and shared responses to metal-based nanocatalysts and UVB.
    Guppi S ;
    Kagan VE
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Metal-based nanocatalysts (NCT) have an irreplaceable role in energy conversion, chemical production, and automotive exhaust purification. Common metal NCT include transition metals (Me) and alloys, which provide active sites for catalytic reactions. However, the same properties that make these NCT very attractive can pose potential health risks. I ...
    Public Domain
  • Characterization of different consumable wires in a novel thermal spray coating aerosol generator and inhalation exposure system
    Characterization of different consumable wires in a novel thermal spray coating aerosol generator and inhalation exposure system.
    Afshari A ;
    Allen C
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Thermal spray coating (TSC) involves spraying a metal coating product that is melted by extremely high temperatures and then applied under air pressure onto a surface. Large amounts of a complex metal aerosol comprised of Fe, Cr, Ni, and Zn are formed during the process, presenting a potentially serious risk to the operator. Information about the h ...
    Public Domain
  • Inhalation of 3dimensional3Dprinting fumes affect the expression of markers associated with neural injury
    Inhalation of 3-dimensional-(3D)-printing fumes affect the expression of markers associated with neural injury.
    Farcas M ;
    Jackson M
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Inhalation of fumes and particulate generated by 3D-printing with plastics has been shown to induce mild systemic inflammation and oxidative stress. One plastic used for printing is polycarbonate (PC). PC contains organic solvents, bisphenols, and other chemicals that are known neurotoxicants. These neurotoxicants can be released as respirable fume ...
    Public Domain
  • A hydrophilic organosilanebased coating blocked acute and subchronic silicainduced lung toxicity in an animal model
    A hydrophilic organosilane-based coating blocked acute and subchronic silica-induced lung toxicity in an animal model.
    Antonini JM ;
    Boyce G
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Fracking is a process in which natural gas-laden rock is fractured to improve removal of underground reserves of gas. Sand is present in the fracking fluid pumped in the well to stabilize the fissures. The handling and use of sand at well sites generate respirable dust by which workers in the oil and gas industry are exposed. Respirable crystalline ...
    Public Domain
  • Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an airliquid interface model of primary normal humanderived bronchial epithelial cells
    Evaluation of pulmonary effects of 3D printer emissions from acrylonitrile butadiene styrene using an air-liquid interface model of primary normal human-derived bronchial epithelial cells.
    Battelli L ;
    Bowers L
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    This study investigated the inhalation toxicity of the emissions from 3-D printing with acrylonitrile butadiene styrene (ABS) filament using an air-liquid interface (ALI) in vitro model. Primary normal human-derived bronchial epithelial cells (NHBEs) were exposed to ABS filament emission particles in an ALI for 4 h. The mean and mode diameters of A ...
    Public Domain
  • Macrophageendothelial cell cross talk in ozoneoxidized carbon black nanoparticle exposure
    Macrophage-endothelial cell cross talk in ozone-oxidized carbon black nanoparticle exposure.
    Bitounis D ;
    Demokritous P
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Apart from natural oxidation of particulate components of air pollution by the reactive gases like ozone (O3), oxidation of carbon black (CB) nanoparticle (NP) is also performed intentionally for industrial applications. Health impacts of these O3-oxidized CB (CBox) NPs are unknown. We hypothesized that macrophage uptake of CBox NPs and secretion o ...
    Public Domain
  • Firefighter dermal exposure assessment with silicone samplers
    Firefighter dermal exposure assessment with silicone samplers.
    Anderson KA ;
    Bonner EM
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Epidemiology studies have demonstrated elevated cancer rates for structural firefighters and a high percentage of cardiovascular events during or following firefighting activity. Polycyclic aromatic hydrocarbons (PAHs) are generated during combustion and are recognized as carcinogens and are implicated in cardiovascular disease progression and even ...
    Public Domain
  • Acute Exposures to Methyl Ethyl Ketone Health Effects and Safety Guidance for Occupational Settings
    Acute Exposures to Methyl Ethyl Ketone, Health Effects, and Safety Guidance for Occupational Settings
    Chittiboyina S
    2022/03/23 | National Institute for Occupational Safety and Health (NIOSH)
    Methyl ethyl ketone (MEK), also known as 2- butanone, is a colorless industrial solvent with a sharp odor that is used in surface coating, synthetic resins, artificial leathers, and glues. MEK is often used in mixtures with acetone, toluene, or alcohols. Acute exposure to MEK in humans has been reported to cause irritation to eyes, nose, and throat ...
    Public Domain
  • CFD Modeling and Laboratory Studies of Dust Cleaning Efficacy of an Efficient Four Stage NonClogging Impingement Filter for FloodedBed Dust Scrubbers
    CFD Modeling and Laboratory Studies of Dust Cleaning Efficacy of an Efficient Four Stage Non-Clogging Impingement Filter for Flooded-Bed Dust Scrubbers
    Gupta, Kailash ;
    Kumar AR
    2022/03/22 | National Institute for Occupational Safety and Health (NIOSH)
    Fibrous-type filters are used to capture dust particles in mining and other occupations where personnel are exposed for prolonged periods. Dust cleansing devices including flooded-bed dust scrubbers use these mesh-type multi-layered filters. These filters trap dust particles efficiently on their surface and inside their mesh. However, their continu ...
  • Line of Duty Death Report Visual Extension Career Captain Drowns After Running Out of Air During Technical Rescue SCUBA Dive North Carolina
    Line of Duty Death Report Visual Extension: Career Captain Drowns After Running Out of Air During Technical Rescue SCUBA Dive – North Carolina
    National Institute for Occupational Safety and Health  ...
    2022/03/22 | Fire Fighter Fatality Investigation and Prevention Program (FFFIPP)
    Summary: A 28-year-old male, part-time, career fire captain died after running out of air and suffering a pulmonary embolism during a technical rescue deep dive. The victim was a member of a local fire department dive team that was trying to recover the body of a civilian who drowned the day before. The captain (Diver 4 and victim) ran low on air a ...
    Public Domain
  • Demographic and psychosocial characteristics associated with use of a prostate cancer survivorship website implications from a multisite randomized controlled trial
    Demographic and psychosocial characteristics associated with use of a prostate cancer survivorship website: implications from a multisite randomized controlled trial.
    Bator A ;
    Diefenbach MA
    2022/03/21 | National Institute for Occupational Safety and Health (NIOSH)
    Background: Many prostate cancer (PC) survivors experience disease and treatment-related symptomatology in both the physical and psychosocial domains. Although the benefits and barriers to using web-based resources for cancer patients are well-documented, less research has focused on the personal characteristics important for efficient tailoring an ...
  • Aerosol and Volatile Organic Compound Emissions During PolyGel Application and Removal
    Aerosol and Volatile Organic Compound Emissions During PolyGel® Application and Removal
    Gould JE
    2022/03/18 | National Institute for Occupational Safety and Health (NIOSH)
    Nail technicians utilize a wide variety of ever-changing nail products that contain or release hazardous chemicals. A new type of nail product created by Gelish is a nail enhancement technology called PolyGel®. This product was made to combine the best aspects of two popular nail services: gel polishing, and acrylic nail extensions. The PolyGel®'s ...
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