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Ocular Infectivity and Replication of a Clade 2.3.4.4b A(H5N1) Influenza Virus Associated With Human Conjunctivitis in a Dairy Farm Worker in the USA: an In-vitro and Ferret Study.

Belser, Jessica A ;

Pulit-Penaloza, Joanna A

July 2025 | The Lancet. Microbe, 2025, v. 6, no. 7

The human eye represents a potential site of influenza A virus (IAV) replication, and an entry point for the virus to reach the respiratory tract. The frequent detection of conjunctivitis among farm workers with confirmed infection with clade 2.3.4.4b A(H5N1) IAV from this ongoing outbreak represents an atypical disease presentation for this virus ...

10/09/2026

Supporting Files

Title : Ocular Infectivity and Replication of a Clade 2.3.4.4b A(H5N1) Influenza Virus Associated With Human Conjunctivitis in a Dairy Farm Worker in the USA: an In-vitro and Ferret Study. Personal Author(s) : Belser, Jessica A;Pulit-Penaloza, Joanna A;Brock, Nicole;Sun, Xiangjie;Kieran, Troy J;Pappas, Claudia;Zeng, Hui;Vu, Michelle N;Lakdawala, Seema S;Tumpey, Terrence M;Maines, Taronna R; Published Date : July 2025 Pages in Document : 101070 (22 pdf pages) Source : The Lancet. Microbe, 2025, v. 6, no. 7 DOI : https://doi.org/10.1016/j.lanmic.2024.101070 Journal Title : The Lancet. Microbe
Belser, J. A., Pulit-Penaloza, J. A., Brock, N., Sun, X., Kieran, T. J., Pappas, C., Zeng, H., Vu, M. N., Lakdawala, S. S., Tumpey, T. M., & Maines, T. R. (2025). Ocular Infectivity and Replication of a Clade 2.3.4.4b A(H5N1) Influenza Virus Associated With Human Conjunctivitis in a Dairy Farm Worker in the USA: an In-vitro and Ferret Study. The Lancet. Microbe, 6(7). https://doi.org/10.1016/j.lanmic.2024.101070

Belser, Jessica A, Joanna A Pulit-Penaloza, Nicole Brock, Xiangjie Sun, Troy J Kieran, Claudia Pappas, and Hui Zeng, et al.. "Ocular Infectivity and Replication of a Clade 2.3.4.4b A(H5N1) Influenza Virus Associated With Human Conjunctivitis in a Dairy Farm Worker in the USA: an In-vitro and Ferret Study." The Lancet. Microbe 6, no. 7 (2025). https://doi.org/10.1016/j.lanmic.2024.101070.

Belser, Jessica A, et al. "Ocular Infectivity and Replication of a Clade 2.3.4.4b A(H5N1) Influenza Virus Associated With Human Conjunctivitis in a Dairy Farm Worker in the USA: an In-vitro and Ferret Study." The Lancet. Microbe, vol. 6, no. 7, 2025. Stacks. https://doi.org/10.1016/j.lanmic.2024.101070.
Export RIS Citation Information. TY - Journal Article AU - Belser, Jessica A AU - Pulit-Penaloza, Joanna A AU - Brock, Nicole AU - Sun, Xiangjie AU - Kieran, Troy J AU - Pappas, Claudia AU - Zeng, Hui AU - Vu, Michelle N AU - Lakdawala, Seema S AU - Tumpey, Terrence M AU - Maines, Taronna R AB - The human eye represents a potential site of influenza A virus (IAV) replication, and an entry point for the virus to reach the respiratory tract. The frequent detection of conjunctivitis among farm workers with confirmed infection with clade 2.3.4.4b A(H5N1) IAV from this ongoing outbreak represents an atypical disease presentation for this virus subtype. We aimed to investigate whether the occurrence of ocular complications reported following clade 2.3.4.4b A(H5N1) virus infection was associated with an enhanced capacity of this virus to replicate in mammalian ocular tissue and cause infection following ocular exposure. AB - Primary human nasal and corneal tissue constructs were infected with A(H5N1) A/Texas/37/2024 (Texas/37), A(H1N1)pdm09 A/Nebraska/14/2019 (Neb/14), and A(H7N7) A/Netherlands/219/2003 (NL/219) viruses (multiplicity of infection [MOI] of 0·01-0·02, 33°C). Corneal tissue constructs were also infected with an expanded panel of IAVs (Texas/37, A[H5N1] A/Michigan/90/2024 [MI/90], A[H5N1] A/Chile/25945/2023 [Chile/25945], NL/219, A/Netherlands/230/2003 [NL/230], and Neb/14; MOI of 0·01, 37°C). In-vitro infections of tissue constructs were used to assess replication kinetics by infectious virus titration. Induction of innate host antiviral responses in infected corneal tissue constructs was assessed by PCR array (MOI of 2·00, 37°C). Ferrets (serologically naive or pre-immune to A[H1N1]pdm09 virus) were inoculated by the ocular route with Texas/37 A(H5N1) virus-using a liquid inoculum (10⁶ plaque forming units [PFU]), aerosol inhalation (15-16 PFU), or ocular-only aerosol exposure (18-132 PFU)-to assess pathogenicity and tropism of the virus following different exposure routes. Transmissibility was assessed by placing serologically naive or pre-immune ferrets inoculated by ocular-only aerosol exposure in direct contact with serologically naive ferrets, monitoring pathogenicity in contact animals, and measuring viral titres in nasal washes of both inoculated and contact ferrets. AB - Nasal and corneal tissue constructs supported replication of all IAVs tested. In corneal tissue constructs, A(H7N7) and A(H1N1)pdm09 viruses reached 10-fold higher overall titres than A(H5N1) isolates. Relatively few genes (n=13) related to antiviral responses were significantly differentially expressed in corneal tissue constructs infected with IAV, with no consistent differential expression among clade 2.3.4.4b A(H5N1) viruses associated with either conjunctivitis or severe respiratory disease, although strain-specific differences were observed. Serologically naive ferrets inoculated by liquid ocular, aerosol inhalation, or aerosol-only ocular routes with Texas/37 virus exhibited a systemic and fatal infection in all animals, transmitting the virus to naive cagemates. By contrast, reduced disease severity following ocular-only aerosol inoculation was observed in animals with pre-existing heterosubtypic immunity. No serologically naive ferrets placed in direct contact with pre-immune ferrets inoculated with Texas/37 virus by the ocular-only aerosol route became infected. AB - A clade 2.3.4.4b A(H5N1) virus from the dairy cattle outbreak in the USA that was first detected in March, 2024, does not appear to possess features indicative of an ocular tropism. However, this virus can maintain a virulent and transmissible phenotype in ferrets following ocular exposure, highlighting the importance of ocular protection. AB - US Centers for Disease Control and Prevention. AB - Author manuscript AN - cdc:261583 C4 - PMC12395545 DO - https://doi.org/10.1016/j.lanmic.2024.101070 IS - 7 J2 - The Lancet. Microbe KW - Female KW - Virus Replication KW - Orthomyxoviridae Infections KW - Farmers KW - Conjunctivitis, Viral KW - Animals KW - Cornea KW - Ferrets KW - Conjunctivitis KW - Farms KW - Humans KW - Influenza A Virus, H5N1 Subtype KW - Eye KW - Influenza, Human KW - Animals KW - Virus Replication KW - Humans KW - Influenza, Human KW - Influenza A Virus, H5N1 Subtype KW - Ferrets KW - Farmers KW - Conjunctivitis KW - Orthomyxoviridae Infections KW - Female KW - Farms KW - Cornea KW - Eye KW - Conjunctivitis, Viral LA - eng PY - 2025 T2 - The Lancet. Microbe T2 - The Lancet. Microbe, 2025, v. 6, no. 7 TI - Ocular Infectivity and Replication of a Clade 2.3.4.4b A(H5N1) Influenza Virus Associated With Human Conjunctivitis in a Dairy Farm Worker in the USA: an In-vitro and Ferret Study. VL - 6 UR - https://stacks.cdc.gov/view/cdc/261583 ER -
Heat Risks in Agriculture: Microclimate Variability and Worker Safety in Sweet Corn and Tobacco.

Edwards, Ryan ;

Lanier, Noel

June 2025 | Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 6

Agricultural work is one of the highest-risk U.S. occupations for heat-related illness (HRIs). Some tall-growing crops can block the cooling effects of wind or contribute to environmental humidity creating warm and humid microclimates (environments directly surrounding workers). The purpose of this study was to assess the differences in environment ...

10/09/2026

Supporting Files

Title : Heat Risks in Agriculture: Microclimate Variability and Worker Safety in Sweet Corn and Tobacco. Personal Author(s) : Edwards, Ryan;Lanier, Noel;Balanay, Jo Anne;Mizelle, Elizabeth; Published Date : June 2025 Pages in Document : 474-481 (16 pdf pages) Source : Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 6 DOI : https://doi.org/10.1080/15459624.2025.2473469 Journal Title : Journal of Occupational and Environmental Hygiene
Edwards, R., Lanier, N., Balanay, J. A., & Mizelle, E. (2025). Heat Risks in Agriculture: Microclimate Variability and Worker Safety in Sweet Corn and Tobacco. Journal of Occupational and Environmental Hygiene, 22(6). https://doi.org/10.1080/15459624.2025.2473469

Edwards, Ryan, Noel Lanier, Jo Anne Balanay, and Elizabeth Mizelle. "Heat Risks in Agriculture: Microclimate Variability and Worker Safety in Sweet Corn and Tobacco." Journal of Occupational and Environmental Hygiene 22, no. 6 (2025). https://doi.org/10.1080/15459624.2025.2473469.

Edwards, Ryan, et al. "Heat Risks in Agriculture: Microclimate Variability and Worker Safety in Sweet Corn and Tobacco." Journal of Occupational and Environmental Hygiene, vol. 22, no. 6, 2025. Stacks. https://doi.org/10.1080/15459624.2025.2473469.
Export RIS Citation Information. TY - Journal Article AU - Edwards, Ryan AU - Lanier, Noel AU - Balanay, Jo Anne AU - Mizelle, Elizabeth AB - Agricultural work is one of the highest-risk U.S. occupations for heat-related illness (HRIs). Some tall-growing crops can block the cooling effects of wind or contribute to environmental humidity creating warm and humid microclimates (environments directly surrounding workers). The purpose of this study was to assess the differences in environmental heat stress within the center of tall-growing crop fields compared to the field perimeter. In the summer of 2023, two heat stress monitors collected daily measurements of wet bulb globe temperature (WBGT) in sweet corn and tobacco fields; results support that WBGT was higher at the field center of sweet corn and significantly higher at the field center of tobacco: 6.7% more hours in sweet corn and 13.6% more hours in tobacco were considered unsafe heat stress risk levels at the field center when compared to unsafe hours at the field perimeter. Unsafe heat stress risk levels were more likely to occur in the afternoons in the corn field while a high majority of all recorded hours in tobacco were considered unsafe, including the morning hours. The risk of laboring inside tall crop rows and heat-related illness should be considered in worker education and heat stress plans. AB - Author manuscript AN - cdc:261582 C4 - PMC12140877 DO - https://doi.org/10.1080/15459624.2025.2473469 IS - 6 J2 - Journal of Occupational and Environmental Hygiene KW - Occupational Exposure KW - Hot Temperature KW - Zea mays KW - Agriculture KW - Heat Stress Disorders KW - Humans KW - Agricultural Workers' Diseases KW - Microclimate KW - Nicotiana KW - Agricultural Workers KW - Evapotranspiration KW - Heat exposure KW - Heat-Related Illnesses KW - Wet-bulb globe temperature KW - Zea mays KW - Microclimate KW - Humans KW - Occupational Exposure KW - Hot Temperature KW - Agriculture KW - Heat Stress Disorders KW - Nicotiana KW - Agricultural Workers' Diseases LA - eng PY - 2025 T2 - Journal of Occupational and Environmental Hygiene T2 - Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 6 TI - Heat Risks in Agriculture: Microclimate Variability and Worker Safety in Sweet Corn and Tobacco. VL - 22 UR - https://stacks.cdc.gov/view/cdc/261582 ER -
Concordance Between Parent-reported and Documented COVID-19 Vaccination Status Among Hospitalized Children and Adolescents: Implications For Vaccine Effectiveness Estimates, May 2021-October 2023.

Hamid, Sarah ;

Simeone, Regina M.

April 2025 | Vaccine, 2025, v. 54

During the U.S. COVID-19 Public Health Emergency (PHE), healthcare providers were required to report all administered COVID-19 vaccines in Immunization Information Systems (IIS), a key data source for vaccine effectiveness (VE) evaluations. Expiration of the PHE and commercialization of COVID-19 vaccines raised concerns about IIS data completeness. ...

10/09/2026

Supporting Files

Title : Concordance Between Parent-reported and Documented COVID-19 Vaccination Status Among Hospitalized Children and Adolescents: Implications For Vaccine Effectiveness Estimates, May 2021-October 2023. Personal Author(s) : Hamid, Sarah;Simeone, Regina M.;Newhams, Margaret M.;Halasa, Natasha;Fleming-Dutra, Katherine E.;Orzel-Lockwood, Amber O.;Wu, Michael J.;Randolph, Adrienne G.;Campbell, Angela P.;Zambrano, Laura D.; Corporate Authors(s) : Overcoming COVID-19 Investigators Published Date : April 2025 Pages in Document : 126891 (27 pdf pages) Source : Vaccine, 2025, v. 54 DOI : https://doi.org/10.1016/j.vaccine.2025.126891 Journal Title : Vaccine
Hamid, S., Simeone, R. M., Newhams, M. M., Halasa, N., Fleming-Dutra, K. E., Orzel-Lockwood, A. O., Wu, M. J., Randolph, A. G., Campbell, A. P., & Zambrano, L. D. (2025). Concordance Between Parent-reported and Documented COVID-19 Vaccination Status Among Hospitalized Children and Adolescents: Implications For Vaccine Effectiveness Estimates, May 2021-October 2023. Vaccine, 54. https://doi.org/10.1016/j.vaccine.2025.126891

Hamid, Sarah, Regina M. Simeone, Margaret M. Newhams, Natasha Halasa, Katherine E. Fleming-Dutra, Amber O. Orzel-Lockwood, Michael J. Wu, Adrienne G. Randolph, Angela P. Campbell, and Laura D. Zambrano. "Concordance Between Parent-reported and Documented COVID-19 Vaccination Status Among Hospitalized Children and Adolescents: Implications For Vaccine Effectiveness Estimates, May 2021-October 2023." Vaccine 54 (2025). https://doi.org/10.1016/j.vaccine.2025.126891.

Hamid, Sarah, et al. "Concordance Between Parent-reported and Documented COVID-19 Vaccination Status Among Hospitalized Children and Adolescents: Implications For Vaccine Effectiveness Estimates, May 2021-October 2023." Vaccine, vol. 54, 2025. Stacks. https://doi.org/10.1016/j.vaccine.2025.126891.
Export RIS Citation Information. TY - Journal Article AU - Hamid, Sarah AU - Simeone, Regina M. AU - Newhams, Margaret M. AU - Halasa, Natasha AU - Fleming-Dutra, Katherine E. AU - Orzel-Lockwood, Amber O. AU - Wu, Michael J. AU - Randolph, Adrienne G. AU - Campbell, Angela P. AU - Zambrano, Laura D. A2 - Overcoming COVID-19 Investigators AB - During the U.S. COVID-19 Public Health Emergency (PHE), healthcare providers were required to report all administered COVID-19 vaccines in Immunization Information Systems (IIS), a key data source for vaccine effectiveness (VE) evaluations. Expiration of the PHE and commercialization of COVID-19 vaccines raised concerns about IIS data completeness. Parental report is an alternative source of vaccination data but might be inaccurate. AB - Using VE surveillance network data during May 2021-October 2023, we compared parent-reported and documented COVID-19 vaccine doses for patients aged 5-18 years admitted to 35 hospitals in 25 states, overall and by case/control status. We calculated percent agreement, kappa, sensitivity, specificity, and positive and negative predictive value (NPV) of parental report. We compared proportions of patients with discordant vaccination history by demographics and incident SARS-CoV-2 infection status. We estimated VE separately using parental report and independently documented sources. AB - Among 3262 patients, agreement between parent-reported and documented COVID-19 vaccination doses was 88 % (kappa = 0.77). Most discordant pairs (346/390) were because of parental over-reporting of doses. Among patients documented as unvaccinated, most (specificity = 90 %) were reported as such by parents; nearly all reported as unvaccinated by parents had no documented vaccination (NPV = 99 %). Discordance decreased with shorter admission-to-interview intervals and varied regionally from 8 % in the Midwest to 16 % in the West. Proportions of discordant reports were similar between patients with and without SARS-CoV-2 infection (11 % vs 13 %). Median days from last vaccine dose to hospital admission was 167 (IQR: 86-288). VE of two doses (99 % original formula) against COVID-19-related hospitalization was 58 % using documented sources and 60 % using parental report. AB - Parental report of COVID-19 vaccination agreed strongly with documented sources, especially among unvaccinated patients. Despite discrepancies from parental overreporting, VE estimates from both sources were similar. As reliance on parental report increases, reducing admission-to-interview time is important for accurate vaccination history. AB - Author manuscript AN - cdc:261581 C4 - PMC12159865 DO - https://doi.org/10.1016/j.vaccine.2025.126891 J2 - Vaccine KW - Adolescent KW - Female KW - Child, Hospitalized KW - Vaccination KW - SARS-CoV-2 KW - Parents KW - COVID-19 KW - Child KW - COVID-19 Vaccines KW - Vaccine Efficacy KW - Hospitalization KW - Male KW - Humans KW - Child, Preschool KW - Concordance KW - COVID-19 vaccination KW - Registry KW - Parental report KW - Vaccine effectiveness KW - Bias KW - Humans KW - Child KW - Adolescent KW - COVID-19 KW - COVID-19 Vaccines KW - Parents KW - Child, Preschool KW - Male KW - Female KW - Vaccine Efficacy KW - Vaccination KW - SARS-CoV-2 KW - Hospitalization KW - Child, Hospitalized LA - eng PY - 2025 T2 - Vaccine T2 - Vaccine, 2025, v. 54 TI - Concordance Between Parent-reported and Documented COVID-19 Vaccination Status Among Hospitalized Children and Adolescents: Implications For Vaccine Effectiveness Estimates, May 2021-October 2023. VL - 54 UR - https://stacks.cdc.gov/view/cdc/261581 ER -
Prenatal Substance Exposure and Multilevel Predictors of Child Protection System Reporting.

Reddy, Julia ;

Halpern, Carolyn T.

July 2025 | The Journal of Pediatrics, 2025, v. 282

To describe child protection system (CPS) reports after delivery and examine associations between individual- and hospital-level predictors and CPS reporting in a cohort of infants with prenatal substance exposure.This state-level, retrospective cohort study used administrative data to analyze births to Black, White, and US-born Hispanic mothers wi ...

10/09/2026

Supporting Files

Title : Prenatal Substance Exposure and Multilevel Predictors of Child Protection System Reporting. Personal Author(s) : Reddy, Julia;Halpern, Carolyn T.;Schiff, Davida M.;Jones, Hendree;Austin, Anna;Faherty, Laura;Rebbe, Rebecca;Vines, Anissa;Putnam-Hornstein, Emily; Published Date : July 2025 Pages in Document : 114546 (17 pdf pages) Source : The Journal of Pediatrics, 2025, v. 282 DOI : https://doi.org/10.1016/j.jpeds.2025.114546 Journal Title : The Journal of Pediatrics
Reddy, J., Halpern, C. T., Schiff, D. M., Jones, H., Austin, A., Faherty, L., Rebbe, R., Vines, A., & Putnam-Hornstein, E. (2025). Prenatal Substance Exposure and Multilevel Predictors of Child Protection System Reporting. The Journal of Pediatrics, 282. https://doi.org/10.1016/j.jpeds.2025.114546

Reddy, Julia, Carolyn T. Halpern, Davida M. Schiff, Hendree Jones, Anna Austin, Laura Faherty, Rebecca Rebbe, Anissa Vines, and Emily Putnam-Hornstein. "Prenatal Substance Exposure and Multilevel Predictors of Child Protection System Reporting." The Journal of Pediatrics 282 (2025). https://doi.org/10.1016/j.jpeds.2025.114546.

Reddy, Julia, et al. "Prenatal Substance Exposure and Multilevel Predictors of Child Protection System Reporting." The Journal of Pediatrics, vol. 282, 2025. Stacks. https://doi.org/10.1016/j.jpeds.2025.114546.
Export RIS Citation Information. TY - Journal Article AU - Reddy, Julia AU - Halpern, Carolyn T. AU - Schiff, Davida M. AU - Jones, Hendree AU - Austin, Anna AU - Faherty, Laura AU - Rebbe, Rebecca AU - Vines, Anissa AU - Putnam-Hornstein, Emily AB - To describe child protection system (CPS) reports after delivery and examine associations between individual- and hospital-level predictors and CPS reporting in a cohort of infants with prenatal substance exposure. AB - This state-level, retrospective cohort study used administrative data to analyze births to Black, White, and US-born Hispanic mothers with documented prenatal substance exposure. We used a random intercept mixed-model with individual- and hospital-level predictors to capture any association between birth hospital and CPS reporting. Interaction terms allowed for different effects dependent on characteristics of the delivering parent and the dominant demographics of the hospital setting. AB - Among 260 525 births during 2018 in California, 2.6% had documented substance exposure, with observed racial differences in substance use and type. Nearly 4% of births to Black mothers had documented cannabis exposure compared with roughly 1% among White and Hispanic mothers. The delivery hospital explained 24% of variance in CPS reporting. Hierarchical models revealed race and insurance-type differences in the likelihood a CPS report followed a substance exposed birth. Namely, publicly-insured births in hospitals where majority births were covered by private insurance had nearly twice the probability of being reported compared with those with private insurance. AB - We found variation in CPS reporting of births with diagnosed substance exposure at the hospital level, and interactions between hospital- and individual-level characteristics in their association with the likelihood of CPS reporting. Associations offer insight into potential areas of bias and inconsistency in policy implementation that might be diminished through improved decision-making tools and provider training. AB - Author manuscript AN - cdc:261580 C4 - PMC13234835 DO - https://doi.org/10.1016/j.jpeds.2025.114546 J2 - The Journal of Pediatrics KW - Pregnancy KW - Retrospective Studies KW - Female KW - Infant KW - Child Protective Services KW - Prenatal Exposure Delayed Effects KW - Male KW - Humans KW - Infant, Newborn KW - Substance-Related Disorders KW - Adult KW - Humans KW - Female KW - Pregnancy KW - Retrospective Studies KW - Child Protective Services KW - Substance-Related Disorders KW - Prenatal Exposure Delayed Effects KW - Infant, Newborn KW - Adult KW - Male KW - Infant LA - eng PY - 2025 T2 - The Journal of Pediatrics T2 - The Journal of Pediatrics, 2025, v. 282 TI - Prenatal Substance Exposure and Multilevel Predictors of Child Protection System Reporting. VL - 282 UR - https://stacks.cdc.gov/view/cdc/261580 ER -
New Resources to Identify Characterized DNA Reference Materials For Pharmacogenetic (PGx) and Human Leukocyte Antigen (HLA) Testing: the Genetic Testing Reference Material (GeT-RM) Program PGx Search Tool and GeT-RM Consolidated PGx and HLA Table.

Scheinfeldt, Laura ;

Kusic, Dara

June 2025 | The Journal of Molecular Diagnostics : JMD, 2025, v. 27, no. 6

Regulations, accreditation standards, and professional guidance require laboratories to use reference materials for assay development, validation, quality control, and proficiency testing of clinical genetic tests. There are, however, few publicly available reference materials for most genetic tests. To address this issue, the CDC's Genetic Testing ...

10/09/2026

Supporting Files

Title : New Resources to Identify Characterized DNA Reference Materials For Pharmacogenetic (PGx) and Human Leukocyte Antigen (HLA) Testing: the Genetic Testing Reference Material (GeT-RM) Program PGx Search Tool and GeT-RM Consolidated PGx and HLA Table. Personal Author(s) : Scheinfeldt, Laura;Kusic, Dara;Gaedigk, Andrea;Turner, Amy J.;Moyer, Ann M.;Pratt, Victoria M.;Kalman, Lisa V.; Published Date : June 2025 Pages in Document : 457-464 (15 pdf pages) Source : The Journal of Molecular Diagnostics : JMD, 2025, v. 27, no. 6 DOI : https://doi.org/10.1016/j.jmoldx.2025.02.008 Journal Title : The Journal of Molecular Diagnostics : JMD
Scheinfeldt, L., Kusic, D., Gaedigk, A., Turner, A. J., Moyer, A. M., Pratt, V. M., & Kalman, L. V. (2025). New Resources to Identify Characterized DNA Reference Materials For Pharmacogenetic (PGx) and Human Leukocyte Antigen (HLA) Testing: the Genetic Testing Reference Material (GeT-RM) Program PGx Search Tool and GeT-RM Consolidated PGx and HLA Table. The Journal of Molecular Diagnostics : JMD, 27(6). https://doi.org/10.1016/j.jmoldx.2025.02.008

Scheinfeldt, Laura, Dara Kusic, Andrea Gaedigk, Amy J. Turner, Ann M. Moyer, Victoria M. Pratt, and Lisa V. Kalman. "New Resources to Identify Characterized DNA Reference Materials For Pharmacogenetic (PGx) and Human Leukocyte Antigen (HLA) Testing: the Genetic Testing Reference Material (GeT-RM) Program PGx Search Tool and GeT-RM Consolidated PGx and HLA Table." The Journal of Molecular Diagnostics : JMD 27, no. 6 (2025). https://doi.org/10.1016/j.jmoldx.2025.02.008.

Scheinfeldt, Laura, et al. "New Resources to Identify Characterized DNA Reference Materials For Pharmacogenetic (PGx) and Human Leukocyte Antigen (HLA) Testing: the Genetic Testing Reference Material (GeT-RM) Program PGx Search Tool and GeT-RM Consolidated PGx and HLA Table." The Journal of Molecular Diagnostics : JMD, vol. 27, no. 6, 2025. Stacks. https://doi.org/10.1016/j.jmoldx.2025.02.008.
Export RIS Citation Information. TY - Journal Article AU - Scheinfeldt, Laura AU - Kusic, Dara AU - Gaedigk, Andrea AU - Turner, Amy J. AU - Moyer, Ann M. AU - Pratt, Victoria M. AU - Kalman, Lisa V. AB - Regulations, accreditation standards, and professional guidance require laboratories to use reference materials for assay development, validation, quality control, and proficiency testing of clinical genetic tests. There are, however, few publicly available reference materials for most genetic tests. To address this issue, the CDC's Genetic Testing Reference Material Program (GeT-RM), the Coriell Institute for Medical Research, and the genetic testing community have conducted 19 studies, including nine for pharmacogenetic (PGx) and human leukocyte antigen (HLA) testing, to generate characterized, renewable, and publicly available DNA samples for use as reference materials. Because new PGx alleles are frequently identified, and allele designations change over time, many samples were reanalyzed for the same gene(s) in subsequent GeT-RM studies. These studies used more comprehensive and sensitive methods and panels that examined additional single-nucleotide variants and/or star alleles to expand and update the consensus genotypes. Up-to-date information is available in two newly established resources: the GeT-RM Consolidated PGx and HLA Table and the GeT-RM PGx Search Tool. These resources contain all available PGx and HLA genotypes for 363 publicly available samples characterized during nine GeT-RM PGx or HLA studies for 34 genes/loci in a consolidated and searchable format. AB - Author manuscript AN - cdc:261579 C4 - PMC12103986 DO - https://doi.org/10.1016/j.jmoldx.2025.02.008 IS - 6 J2 - The Journal of Molecular Diagnostics : JMD KW - Genetic Testing KW - Pharmacogenetics KW - Alleles KW - Humans KW - Pharmacogenomic Testing KW - Reference Standards KW - Histocompatibility Testing KW - HLA Antigens KW - DNA KW - Humans KW - HLA Antigens KW - Pharmacogenomic Testing KW - Alleles KW - Reference Standards KW - Pharmacogenetics KW - Genetic Testing KW - Histocompatibility Testing KW - DNA LA - eng PY - 2025 T2 - The Journal of Molecular Diagnostics : JMD T2 - The Journal of Molecular Diagnostics : JMD, 2025, v. 27, no. 6 TI - New Resources to Identify Characterized DNA Reference Materials For Pharmacogenetic (PGx) and Human Leukocyte Antigen (HLA) Testing: the Genetic Testing Reference Material (GeT-RM) Program PGx Search Tool and GeT-RM Consolidated PGx and HLA Table. VL - 27 UR - https://stacks.cdc.gov/view/cdc/261579 ER -
Viviparity and Obligate Blood Feeding: Tsetse Flies as a Unique Research System to Study Climate Change.

Benoit, Joshua B. ;

Weaving, Hester

June 2025 | Current Opinion in Insect Science, 2025, v. 69

Tsetse flies (Glossina species) are unique organisms that combine several remarkable traits: they are obligate blood feeders, serve as critical vectors for African trypanosomes, and reproduce through adenotrophic viviparity - a process in which offspring are nourished with milk-like secretions before being born live. Here, we explore how climate ch ...

10/09/2026

Supporting Files

Title : Viviparity and Obligate Blood Feeding: Tsetse Flies as a Unique Research System to Study Climate Change. Personal Author(s) : Benoit, Joshua B.;Weaving, Hester;McLellan, Callum;Terblanche, John S.;Attardo, Geoffrey M.;English, Sinead; Published Date : June 2025 Pages in Document : 101369 (13 pdf pages) Source : Current Opinion in Insect Science, 2025, v. 69 DOI : https://doi.org/10.1016/j.cois.2025.101369 Journal Title : Current Opinion in Insect Science
Benoit, J. B., Weaving, H., McLellan, C., Terblanche, J. S., Attardo, G. M., & English, S. (2025). Viviparity and Obligate Blood Feeding: Tsetse Flies as a Unique Research System to Study Climate Change. Current Opinion in Insect Science, 69. https://doi.org/10.1016/j.cois.2025.101369

Benoit, Joshua B., Hester Weaving, Callum McLellan, John S. Terblanche, Geoffrey M. Attardo, and Sinead English. "Viviparity and Obligate Blood Feeding: Tsetse Flies as a Unique Research System to Study Climate Change." Current Opinion in Insect Science 69 (2025). https://doi.org/10.1016/j.cois.2025.101369.

Benoit, Joshua B., et al. "Viviparity and Obligate Blood Feeding: Tsetse Flies as a Unique Research System to Study Climate Change." Current Opinion in Insect Science, vol. 69, 2025. Stacks. https://doi.org/10.1016/j.cois.2025.101369.
Export RIS Citation Information. TY - Journal Article AU - Benoit, Joshua B. AU - Weaving, Hester AU - McLellan, Callum AU - Terblanche, John S. AU - Attardo, Geoffrey M. AU - English, Sinead AB - Tsetse flies (Glossina species) are unique organisms that combine several remarkable traits: they are obligate blood feeders, serve as critical vectors for African trypanosomes, and reproduce through adenotrophic viviparity - a process in which offspring are nourished with milk-like secretions before being born live. Here, we explore how climate change will impact the physiological processes associated with live birth in tsetse. This includes considerations of how blood feeding, host-pathogen interactions, and host-symbiont dynamics are likely to be impacted by thermal shifts. The highly specialized biology of tsetse flies suggests that this system is likely to have a distinctive response to climate change. Thus, detailed empirical research into these unique features is paramount for predicting tsetse population dynamics under climate change, with caution required when generalizing from other well-studied vectors with contrasting ecology and life histories such as mosquitoes and ticks. At the same time, the reproductive biology of tsetse, as well as microbiome and feeding dynamics, allow for a powerful model to investigate climate change through the lens of pregnancy and associated physiological adaptations in an extensively researched invertebrate. AB - Author manuscript AN - cdc:261578 C4 - PMC12741855 DO - https://doi.org/10.1016/j.cois.2025.101369 J2 - Current Opinion in Insect Science KW - Climate Change KW - Host-Pathogen Interactions KW - Viviparity, Nonmammalian KW - Animals KW - Tsetse Flies KW - Insect Vectors KW - Feeding Behavior KW - viviparity KW - heat stress KW - trypanosome KW - metabolism KW - climate change KW - Animals KW - Tsetse Flies KW - Climate Change KW - Viviparity, Nonmammalian KW - Feeding Behavior KW - Insect Vectors KW - Host-Pathogen Interactions LA - eng PY - 2025 T2 - Current Opinion in Insect Science T2 - Current Opinion in Insect Science, 2025, v. 69 TI - Viviparity and Obligate Blood Feeding: Tsetse Flies as a Unique Research System to Study Climate Change. VL - 69 UR - https://stacks.cdc.gov/view/cdc/261578 ER -
A Lightweight Powered Hip Exoskeleton With Parallel Actuation For Frontal and Sagittal Plane Assistance.

Archangeli, Dante ;

Ortolano, Brendon

February 2025 | IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society, 2025, v. 41

Wearable robots and powered exoskeletons may improve ambulation for millions of individuals with poor mobility. Powered exoskeletons primarily assist in the sagittal plane to improve walking efficiency and speed. However, individuals with poor mobility often have limited mediolateral balance, which requires torque generation in the frontal plane. E ...

10/09/2026

Supporting Files

Title : A Lightweight Powered Hip Exoskeleton With Parallel Actuation For Frontal and Sagittal Plane Assistance. Personal Author(s) : Archangeli, Dante;Ortolano, Brendon;Murray, Rosemarie;Gabert, Lukas;Lenzi, Tommaso; Published Date : February 2025 Pages in Document : 1-17 (42 pdf pages) Source : IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society, 2025, v. 41 DOI : https://doi.org/10.1109/tro.2025.3539172 Journal Title : IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society
Archangeli, D., Ortolano, B., Murray, R., Gabert, L., & Lenzi, T. (2025). A Lightweight Powered Hip Exoskeleton With Parallel Actuation For Frontal and Sagittal Plane Assistance. IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society, 41. https://doi.org/10.1109/tro.2025.3539172

Archangeli, Dante, Brendon Ortolano, Rosemarie Murray, Lukas Gabert, and Tommaso Lenzi. "A Lightweight Powered Hip Exoskeleton With Parallel Actuation For Frontal and Sagittal Plane Assistance." IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society 41 (2025). https://doi.org/10.1109/tro.2025.3539172.

Archangeli, Dante, et al. "A Lightweight Powered Hip Exoskeleton With Parallel Actuation For Frontal and Sagittal Plane Assistance." IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society, vol. 41, 2025. Stacks. https://doi.org/10.1109/tro.2025.3539172.
Export RIS Citation Information. TY - Journal Article AU - Archangeli, Dante AU - Ortolano, Brendon AU - Murray, Rosemarie AU - Gabert, Lukas AU - Lenzi, Tommaso AB - Wearable robots and powered exoskeletons may improve ambulation for millions of individuals with poor mobility. Powered exoskeletons primarily assist in the sagittal plane to improve walking efficiency and speed. However, individuals with poor mobility often have limited mediolateral balance, which requires torque generation in the frontal plane. Existing hip exoskeletons that assist in both the sagittal and frontal planes are too heavy and bulky for use in the real world. Here we present the kinematic model, mechatronic design, and benchtop and human testing of a powered hip exoskeleton with a unique parallel kinematic actuator. The exoskeleton is lightweight (5.3 kg), has a slim profile, and can generate 30 N·m and 20 N·m of torque during gait in the sagittal and frontal planes. The exoskeleton torque density is 5.7 N·m/kg-53% higher than previously possible with series kinematic design. Testing with five healthy subjects indicate that frontal plane torques applied during stance or swing can alter step width, while sagittal plane torque can assist with hip flexion and extension. A device with these characteristics may improve both gait economy and balance in the real world. AB - Author manuscript AN - cdc:261577 C4 - PMC11926883 DO - https://doi.org/10.1109/tro.2025.3539172 J2 - IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society KW - Gait KW - Wearable Electronic Devices KW - Walking KW - Exoskeleton Device KW - Healthy Volunteers KW - Torque KW - Biomechanical Phenomena KW - Parallel robots KW - physically assistive devices KW - prosthetics and exoskeletons KW - wearable robots KW - Biomechanical Phenomena KW - Exoskeleton Device KW - Healthy Volunteers KW - Torque KW - Wearable Electronic Devices KW - Walking KW - Gait LA - eng PY - 2025 T2 - IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society T2 - IEEE Transactions on Robotics : A Publication of the IEEE Robotics and Automation Society, 2025, v. 41 TI - A Lightweight Powered Hip Exoskeleton With Parallel Actuation For Frontal and Sagittal Plane Assistance. VL - 41 UR - https://stacks.cdc.gov/view/cdc/261577 ER -
Tendências na Prevenção da Transmissão Vertical do HIV nas Unidades Sanitárias-Ajuda do PEPFAR em Moçambique, 2017-2023

Langa, Judite ;

de Deus, Maria Inês

March 21, 2025 | Revista Mocambicana de Ciencias de Saude, 2025, v. 10, no. 2

Mozambique implements the prevention of mother-to-child transmission (PMTCT) of HIV as part of the national program since 2022. Despite the gains, vertical transmission rates continue high, estimated at 9% in 2023. We describe the progress of PMTCT in health facilities (HF) with PEPFAR support.We analyzed routine data of 656 HF with PEPFAR support, ...

10/09/2026

Supporting Files

Title : Tendências na Prevenção da Transmissão Vertical do HIV nas Unidades Sanitárias-Ajuda do PEPFAR em Moçambique, 2017-2023 Personal Author(s) : Langa, Judite;de Deus, Maria Inês;Arciniegas, Sarah;Wate, Argentina;Bila, Erica;Alfândega, Arla;Mate, Nelice;Rungo, Irene;Azambuja, Gizela;Tibana, Kwalila;Eliseu, Námita; Published Date : March 21, 2025 Pages in Document : 32-38 (12 pdf pages) Source : Revista Mocambicana de Ciencias de Saude, 2025, v. 10, no. 2 DOI : https://doi.org/10.1001/jama.283.9.1175 Journal Title : Revista Mocambicana de Ciencias de Saude
Langa, J., de Deus, M. I., Arciniegas, S., Wate, A., Bila, E., Alfândega, A., Mate, N., Rungo, I., Azambuja, G., Tibana, K., & Eliseu, N. (2025). Tendências na Prevenção da Transmissão Vertical do HIV nas Unidades Sanitárias-Ajuda do PEPFAR em Moçambique, 2017-2023. Revista Mocambicana de Ciencias de Saude, 10(2). https://doi.org/10.1001/jama.283.9.1175

Langa, Judite, Maria Inês de Deus, Sarah Arciniegas, Argentina Wate, Erica Bila, Arla Alfândega, and Nelice Mate, et al.. "Tendências na Prevenção da Transmissão Vertical do HIV nas Unidades Sanitárias-Ajuda do PEPFAR em Moçambique, 2017-2023." Revista Mocambicana de Ciencias de Saude 10, no. 2 (2025). https://doi.org/10.1001/jama.283.9.1175.

Langa, Judite, et al. "Tendências na Prevenção da Transmissão Vertical do HIV nas Unidades Sanitárias-Ajuda do PEPFAR em Moçambique, 2017-2023." Revista Mocambicana de Ciencias de Saude, vol. 10, no. 2, 2025. Stacks. https://doi.org/10.1001/jama.283.9.1175.
Export RIS Citation Information. TY - Journal Article AU - Langa, Judite AU - de Deus, Maria Inês AU - Arciniegas, Sarah AU - Wate, Argentina AU - Bila, Erica AU - Alfândega, Arla AU - Mate, Nelice AU - Rungo, Irene AU - Azambuja, Gizela AU - Tibana, Kwalila AU - Eliseu, Námita AB - Mozambique implements the prevention of mother-to-child transmission (PMTCT) of HIV as part of the national program since 2022. Despite the gains, vertical transmission rates continue high, estimated at 9% in 2023. We describe the progress of PMTCT in health facilities (HF) with PEPFAR support. AB - We analyzed routine data of 656 HF with PEPFAR support, during the 2017 - 2023 fiscal years (October-September). We calculated the following proportions: pregnant women (PW) at first antenatal care consultation (ANC1) that knew their HIV status; HIV positive PW at ANC; PW on antiretroviral treatment (ART); PW on ART with a documented viral load (VL); PW with suppressed VL (VLS, defined as <1.000 copies/ml); HIV exposed children (HEI) tested up to 12 months, with a HIV positive result; HEI positive in ART. Data were analyzed by fiscal year (October - September). AB - During 2017-2023, the proportion of PW knowing their HIV status at ANC1 increased from 90,4% (863.181/954.933) to 99,9% (1.047.870/1.049.225); the proportion of PW on ART remained above 99%; the proportion of PW with VL test increased from 24,5% (9.862/40.293) to 74,9% (46.292/61.818); and the VLS increased from 51,4% (5.073/9.862) to 88,5% (40.950/46.292). During 2017-2023, HEI testing increased from 76,5% (64.322/84.038) to 96,0% (82.689/86.132), and testing positivity decreased from 8,5% (5.487/64.322) to 2,5% (2.075/82.689); during 2018-2023, the proportion of HIV positive HEI on ART increased from 82,7% (3.521/4.256) to 93,3% (1.936/2.075). AB - Health facilities with PEPFAR support achieved progress in PMTCT. Continued implementation of sound interventions to improve ART initiation and retention, VLS and ART linkage of HEI testing HIV positive can lead to additional reduction of vertical transmission and its elimination as a public health problem in the country. AB - Author manuscript AN - cdc:261576 C4 - PMC11926990 DO - https://doi.org/10.1001/jama.283.9.1175 IS - 2 J2 - Revista Mocambicana de Ciencias de Saude KW - HIV KW - Infectious Disease Transmission, Vertical KW - Breast Feeding KW - Pregnant People KW - Mulheres grávidas e lactantes KW - Crianças expostas ao HIV KW - Transmissão vertical KW - Prevenção da transmissão vertical KW - Pregnant and breastfeeding women KW - HIV exposed children KW - Vertical transmission KW - HIV KW - Pregnant People KW - Breast Feeding KW - HIV KW - Infectious Disease Transmission, Vertical LA - por PY - 2025 T2 - Revista Mocambicana de Ciencias de Saude T2 - Revista Mocambicana de Ciencias de Saude, 2025, v. 10, no. 2 TI - Tendências na Prevenção da Transmissão Vertical do HIV nas Unidades Sanitárias-Ajuda do PEPFAR em Moçambique, 2017-2023 VL - 10 UR - https://stacks.cdc.gov/view/cdc/261576 ER -
Alinhamento de Dados Entre os Sistemas de Reporte de HIV em Moçambique, 2017-2023.

Tiberi, Orrin ;

Templin, Lindsay

March 21, 2025 | Revista Mocambicana de Ciencias de Saude, 2025, v. 10, no. 2

Data quality improvements have aimed to align national reporting systems for Ministry of Health (MISAU) and PEPFAR. For example, in 2019 the patient Master Card improved systematic data collection process and sites were selected for intensified support including data quality activities (AJUDA). This study aims to compare reported data between MISAU ...

10/09/2026

Supporting Files

Title : Alinhamento de Dados Entre os Sistemas de Reporte de HIV em Moçambique, 2017-2023. Personal Author(s) : Tiberi, Orrin;Templin, Lindsay;Ferreira, Ferreira;Nhaguiombe, Herminio;Couto, Aleny;Lara, Joe;Keating, Ryan;Mizela, Jose;Matsimbe, Lucio;Magaia, Helio;da Cunha, Morais; Published Date : March 21, 2025 Pages in Document : 23-26 (8 pdf pages) Source : Revista Mocambicana de Ciencias de Saude, 2025, v. 10, no. 2 DOI : https://doi.org/10.1186/s12911-016-0354-8 Journal Title : Revista Mocambicana de Ciencias de Saude
Tiberi, O., Templin, L., Ferreira, F., Nhaguiombe, H., Couto, A., Lara, J., Keating, R., Mizela, J., Matsimbe, L., Magaia, H., & da Cunha, M. (2025). Alinhamento de Dados Entre os Sistemas de Reporte de HIV em Moçambique, 2017-2023. Revista Mocambicana de Ciencias de Saude, 10(2). https://doi.org/10.1186/s12911-016-0354-8

Tiberi, Orrin, Lindsay Templin, Ferreira Ferreira, Herminio Nhaguiombe, Aleny Couto, Joe Lara, and Ryan Keating, et al.. "Alinhamento de Dados Entre os Sistemas de Reporte de HIV em Moçambique, 2017-2023." Revista Mocambicana de Ciencias de Saude 10, no. 2 (2025). https://doi.org/10.1186/s12911-016-0354-8.

Tiberi, Orrin, et al. "Alinhamento de Dados Entre os Sistemas de Reporte de HIV em Moçambique, 2017-2023." Revista Mocambicana de Ciencias de Saude, vol. 10, no. 2, 2025. Stacks. https://doi.org/10.1186/s12911-016-0354-8.
Export RIS Citation Information. TY - Journal Article AU - Tiberi, Orrin AU - Templin, Lindsay AU - Ferreira, Ferreira AU - Nhaguiombe, Herminio AU - Couto, Aleny AU - Lara, Joe AU - Keating, Ryan AU - Mizela, Jose AU - Matsimbe, Lucio AU - Magaia, Helio AU - da Cunha, Morais AB - Data quality improvements have aimed to align national reporting systems for Ministry of Health (MISAU) and PEPFAR. For example, in 2019 the patient Master Card improved systematic data collection process and sites were selected for intensified support including data quality activities (AJUDA). This study aims to compare reported data between MISAU and PEPFAR to understand data alignment trends. AB - The annual number of PLHIV on ART, newly initiating ART and HIV status in first ANC visit as reported by MISAU and PEPFAR were compared for 2017-2023. The absolute difference was calculated as MISAU-reported number minus PEPFAR-reported number; proportional absolute difference as the absolute difference over the MISAU-reported number and assessed the slope of the difference over time. AB - During 2017-2023, median absolute difference for PLHIV on ART was 104. 940 (range = 154. 901 [2018] to 1. 598 [2020]), and median proportional difference was 5, 0% (range = 0, 1% [2020] to 12,8% [2018]), with a trend towards improved concordance. A similar trend was found in positive HIV status at first ANC (10,4% [2017] to 0,0% [2023]), as well as with newly initiated on ART (2,7% [2017] to 0.3% [2023]). AB - In the three indicators analyzed, there were improvements in data alignment between the years of 2017 and 2023, with increased alignment in different years and for different reasons. Continued improvements will support programming and increase certainty for tracking progress toward the UNAIDS 95-95-95 goals to end HIV. AB - Author manuscript AN - cdc:261575 C4 - PMC11926987 DO - https://doi.org/10.1186/s12911-016-0354-8 IS - 2 J2 - Revista Mocambicana de Ciencias de Saude KW - HIV KW - Data Accuracy KW - HIV KW - Qualidade de Dados KW - Alinhamento de Dados KW - PEPFAR KW - TARV KW - HIV KW - Data Accuracy LA - por PY - 2025 T2 - Revista Mocambicana de Ciencias de Saude T2 - Revista Mocambicana de Ciencias de Saude, 2025, v. 10, no. 2 TI - Alinhamento de Dados Entre os Sistemas de Reporte de HIV em Moçambique, 2017-2023. VL - 10 UR - https://stacks.cdc.gov/view/cdc/261575 ER -
Voice of the Patient: People With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) Share in Their Own Words.

Brimmer, Dana J. ;

Lin, Jin-Mann S.

March 21, 2025 | Fatigue : Biomedicine, Health & Behavior, 2025, v. 13, no. 2

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, debilitating illness affecting millions of people worldwide. Patients with ME/CFS often feel misunderstood and report facing barriers to healthcare utilization.We report on a Voice of the Patient (VOP) series that used tenets from photovoice and hermeneutic phenomenology meth ...

10/09/2026

Supporting Files

Title : Voice of the Patient: People With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) Share in Their Own Words. Personal Author(s) : Brimmer, Dana J.;Lin, Jin-Mann S.;Unger, Elizabeth R.; Published Date : March 21, 2025 Pages in Document : 1-11 (12 pdf pages) Source : Fatigue : Biomedicine, Health & Behavior, 2025, v. 13, no. 2 DOI : https://doi.org/10.1080/21641846.2024.2444826 Journal Title : Fatigue : Biomedicine, Health & Behavior
Brimmer, D. J., Lin, J. M. S., & Unger, E. R. (2025). Voice of the Patient: People With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) Share in Their Own Words. Fatigue : Biomedicine, Health & Behavior, 13(2). https://doi.org/10.1080/21641846.2024.2444826

Brimmer, Dana J., Jin-Mann S. Lin, and Elizabeth R. Unger. "Voice of the Patient: People With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) Share in Their Own Words." Fatigue : Biomedicine, Health & Behavior 13, no. 2 (2025). https://doi.org/10.1080/21641846.2024.2444826.

Brimmer, Dana J., et al. "Voice of the Patient: People With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) Share in Their Own Words." Fatigue : Biomedicine, Health & Behavior, vol. 13, no. 2, 2025. Stacks. https://doi.org/10.1080/21641846.2024.2444826.
Export RIS Citation Information. TY - Journal Article AU - Brimmer, Dana J. AU - Lin, Jin-Mann S. AU - Unger, Elizabeth R. AB - Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, debilitating illness affecting millions of people worldwide. Patients with ME/CFS often feel misunderstood and report facing barriers to healthcare utilization. AB - We report on a Voice of the Patient (VOP) series that used tenets from photovoice and hermeneutic phenomenology methods. The approach prioritized respecting and engaging patients as they share individual experiences of living with ME/CFS. AB - We developed a 5-step process that could be replicated for interviewing patients in their own words. The process prioritized respecting patients while developing, documenting, and sharing individual accounts of living with ME/CFS. The standardized process for gathering each VOP story enabled individuals to share and participate on their own terms. AB - Over four years, eight VOP stories were completed and posted on CDC's ME/CFS website. The stories received over 196,000 page views. Each story was completed in approximately six months. Participants expressed gratitude for the opportunity to share experiences and were appreciative of the process that involved them in the development of stories. AB - Qualitative methods guided the process for participants taking a central role in sharing stories, which in turn may help educate about patient experiences with ME/CFS. Standardization of steps enabled consistency and transparency. Building flexibility into the process allowed interviewing a range of people with ME/CFS (i.e. bed bound to working) and enabled patients to give narratives in their voice. This process may help to share experiences of people with other chronic diseases or infection associated chronic conditions. AB - Author manuscript AN - cdc:261574 C4 - PMC11926923 DO - https://doi.org/10.1080/21641846.2024.2444826 IS - 2 J2 - Fatigue : Biomedicine, Health & Behavior KW - Fatigue Syndrome, Chronic KW - Myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) KW - Voice of the Patient (VOP) KW - Qualitative methods KW - Fatigue Syndrome, Chronic LA - eng PY - 2025 T2 - Fatigue : Biomedicine, Health & Behavior T2 - Fatigue : Biomedicine, Health & Behavior, 2025, v. 13, no. 2 TI - Voice of the Patient: People With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) Share in Their Own Words. VL - 13 UR - https://stacks.cdc.gov/view/cdc/261574 ER -
Call to Action: Contribute to the Development of the Third Edition of the Physical Activity Guidelines For Americans.

Piercy, Katrina L. ;

Vaux-Bjerke, Alison

March 21, 2025 | Translational Journal of the American College of Sports Medicine, 2025, v. 10, no. 1

Every 10 yr, the US Department of Health and Human Services (HHS) reviews the body of evidence for physical activity and health outcomes and provides updated guidance on the amounts and types of physical activity necessary to get and stay healthy (1). Developing the Physical Activity Guidelines for Americans (Guidelines) is a multiyear process, beg ...

10/09/2026

Supporting Files

Title : Call to Action: Contribute to the Development of the Third Edition of the Physical Activity Guidelines For Americans. Personal Author(s) : Piercy, Katrina L.;Vaux-Bjerke, Alison;Polster, Malorie;Fulton, Janet E.;George, Stephanie;Rose, Kenneth M.;Whitfield, Geoffrey P.;Wolff-Hughes, Dana L.;Barnett, Elizabeth Y.; Published Date : March 21, 2025 Pages in Document : 7 pdf pages Source : Translational Journal of the American College of Sports Medicine, 2025, v. 10, no. 1 DOI : https://doi.org/10.1249/tjx.0000000000000275 Journal Title : Translational Journal of the American College of Sports Medicine
Piercy, K. L., Vaux-Bjerke, A., Polster, M., Fulton, J. E., George, S., Rose, K. M., Whitfield, G. P., Wolff-Hughes, D. L., & Barnett, E. Y. (2025). Call to Action: Contribute to the Development of the Third Edition of the Physical Activity Guidelines For Americans. Translational Journal of the American College of Sports Medicine, 10(1). https://doi.org/10.1249/tjx.0000000000000275

Piercy, Katrina L., Alison Vaux-Bjerke, Malorie Polster, Janet E. Fulton, Stephanie George, Kenneth M. Rose, Geoffrey P. Whitfield, Dana L. Wolff-Hughes, and Elizabeth Y. Barnett. "Call to Action: Contribute to the Development of the Third Edition of the Physical Activity Guidelines For Americans." Translational Journal of the American College of Sports Medicine 10, no. 1 (2025). https://doi.org/10.1249/tjx.0000000000000275.

Piercy, Katrina L., et al. "Call to Action: Contribute to the Development of the Third Edition of the Physical Activity Guidelines For Americans." Translational Journal of the American College of Sports Medicine, vol. 10, no. 1, 2025. Stacks. https://doi.org/10.1249/tjx.0000000000000275.
Export RIS Citation Information. TY - Journal Article AU - Piercy, Katrina L. AU - Vaux-Bjerke, Alison AU - Polster, Malorie AU - Fulton, Janet E. AU - George, Stephanie AU - Rose, Kenneth M. AU - Whitfield, Geoffrey P. AU - Wolff-Hughes, Dana L. AU - Barnett, Elizabeth Y. AB - Every 10 yr, the US Department of Health and Human Services (HHS) reviews the body of evidence for physical activity and health outcomes and provides updated guidance on the amounts and types of physical activity necessary to get and stay healthy (1). Developing the Physical Activity Guidelines for Americans (Guidelines) is a multiyear process, beginning with the identification of key topics, and then the solicitation and appointment of a group of academic experts to serve on the Advisory Committee. The Physical Activity Guidelines Advisory Committee conducts a series of systematic literature reviews on physical-activity-related topics and summarizes the findings in a scientific report, which is then used by the Federal Government to develop the Guidelines. AB - Planning is underway for the third edition of the Guidelines, anticipated for release in 2028. A federal planning group led by HHS's Office of Disease Prevention and Health Promotion (ODPHP), the National Institutes of Health (NIH), and the Centers for Disease Control and Prevention (CDC) organized a listening session in May 2024 and invited those with expertise in selected topics to participate. Experts from the World Health Organization and the Canadian Physical Activity Guidelines were also invited as key international collaborators. The goals of the listening session were to assess the body of knowledge on selected emerging topics that can inform the next edition of the Guidelines, identify research gaps that can be shared with the research community, and begin engaging physical activity researchers and health professionals in the planning for the next edition. AB - Author manuscript AN - cdc:261573 C4 - PMC11926852 DO - https://doi.org/10.1249/tjx.0000000000000275 IS - 1 J2 - Translational Journal of the American College of Sports Medicine KW - Outcome Assessment, Health Care KW - Exercise KW - Advisory Committees KW - Health Promotion KW - Evidence Gaps KW - Advisory Committees KW - Evidence Gaps KW - Health Promotion KW - Exercise KW - Outcome Assessment, Health Care LA - eng PY - 2025 T2 - Translational Journal of the American College of Sports Medicine T2 - Translational Journal of the American College of Sports Medicine, 2025, v. 10, no. 1 TI - Call to Action: Contribute to the Development of the Third Edition of the Physical Activity Guidelines For Americans. VL - 10 UR - https://stacks.cdc.gov/view/cdc/261573 ER -
Contribution of Individual Support Components to Roof Stability in a Longwall Gateroad.

Khademian, Zoheir ;

Sears, Morgan

March 21, 2025 | Mining, Metallurgy & Exploration, 2025, v. 41, no. 2

According to the 2010-2019 Mine Safety and Health Administration (MSHA) accident report database, 91% of reported ground control accidents in US longwall mines were caused by roof instability. Gateroads are subjected to significant changes in loading conditions from the development to the longwall abutment loading phases. When combined with thinly ...

10/09/2026

Supporting Files

Title : Contribution of Individual Support Components to Roof Stability in a Longwall Gateroad. Personal Author(s) : Khademian, Zoheir;Sears, Morgan; Published Date : March 21, 2025 Pages in Document : 695-705 (22 pdf pages) Source : Mining, Metallurgy & Exploration, 2025, v. 41, no. 2 DOI : https://doi.org/10.1007/s42461-024-00925-3 Journal Title : Mining, Metallurgy & Exploration
Khademian, Z., & Sears, M. (2025). Contribution of Individual Support Components to Roof Stability in a Longwall Gateroad. Mining, Metallurgy & Exploration, 41(2). https://doi.org/10.1007/s42461-024-00925-3

Khademian, Zoheir and Morgan Sears. "Contribution of Individual Support Components to Roof Stability in a Longwall Gateroad." Mining, Metallurgy & Exploration 41, no. 2 (2025). https://doi.org/10.1007/s42461-024-00925-3.

Khademian, Zoheir, and Morgan Sears "Contribution of Individual Support Components to Roof Stability in a Longwall Gateroad." Mining, Metallurgy & Exploration, vol. 41, no. 2, 2025. Stacks. https://doi.org/10.1007/s42461-024-00925-3.
Export RIS Citation Information. TY - Journal Article AU - Khademian, Zoheir AU - Sears, Morgan AB - According to the 2010-2019 Mine Safety and Health Administration (MSHA) accident report database, 91% of reported ground control accidents in US longwall mines were caused by roof instability. Gateroads are subjected to significant changes in loading conditions from the development to the longwall abutment loading phases. When combined with thinly bedded shale roof, found in many US longwall coal mines, the design of efficient roof support becomes challenging. In previous work, the bonded block modeling (BBM) of roof by UDEC was validated against field extensometer measurements in a longwall entry roof at a 180-m depth of cover. The BBM was shown capable of capturing delamination and buckling of shale roof, one of the main roof instability mechanisms in longwall mines. This paper presents the recent findings on the roof-support interaction using BBM models of the same longwall entry. The effects of cable bolts, roof bolt density, and strap support on potential roof instability are studied. Results demonstrate the potential for BBM numerical models to help understand the complex roof and support system interactions and to assist with optimizing gateroad support systems. AB - Author manuscript AN - cdc:261572 C4 - PMC11926887 DO - https://doi.org/10.1007/s42461-024-00925-3 IS - 2 J2 - Mining, Metallurgy & Exploration KW - Coal KW - Accidents KW - Entry roof stability KW - Roof-support interaction KW - Bonded block models KW - Trigons KW - Longwall mine KW - Accidents KW - Coal LA - eng PY - 2025 T2 - Mining, Metallurgy & Exploration T2 - Mining, Metallurgy & Exploration, 2025, v. 41, no. 2 TI - Contribution of Individual Support Components to Roof Stability in a Longwall Gateroad. VL - 41 UR - https://stacks.cdc.gov/view/cdc/261572 ER -
Airborne Bacteria in Institutional and Commercial Buildings in Korea: Characterization With 16S RRNA Gene Sequencing and Association With Environmental Conditions.

Kim, Yea Joon ;

Lee, Bong Gu

March 21, 2025 | Aerosol Science and Technology : the Journal of the American Association for Aerosol Research, 2025, v. 58, no. 11

Information on microorganisms in indoor air of various institutional and commercial buildings has significant value in a public health management perspective. However, there is a lack of prior research comparing indoor airborne microbiota across different categories of those buildings. We characterized indoor airborne bacteria in 10 buildings (two ...

10/09/2026

Supporting Files

Title : Airborne Bacteria in Institutional and Commercial Buildings in Korea: Characterization With 16S RRNA Gene Sequencing and Association With Environmental Conditions. Personal Author(s) : Kim, Yea Joon;Lee, Bong Gu;Shim, Joo Eun;Lee, Hyesoo;Park, Ju-Hyeong;Yeo, Min-Kyeong; Published Date : March 21, 2025 Pages in Document : 1281-1292 (23 pdf pages) Source : Aerosol Science and Technology : the Journal of the American Association for Aerosol Research, 2025, v. 58, no. 11 DOI : https://doi.org/10.1080/02786826.2024.2387135 Journal Title : Aerosol Science and Technology : the Journal of the American Association for Aerosol Research
Kim, Y. J., Lee, B. G., Shim, J. E., Lee, H., Park, J. H., & Yeo, M. K. (2025). Airborne Bacteria in Institutional and Commercial Buildings in Korea: Characterization With 16S RRNA Gene Sequencing and Association With Environmental Conditions. Aerosol Science and Technology : the Journal of the American Association for Aerosol Research, 58(11). https://doi.org/10.1080/02786826.2024.2387135

Kim, Yea Joon, Bong Gu Lee, Joo Eun Shim, Hyesoo Lee, Ju-Hyeong Park, and Min-Kyeong Yeo. "Airborne Bacteria in Institutional and Commercial Buildings in Korea: Characterization With 16S RRNA Gene Sequencing and Association With Environmental Conditions." Aerosol Science and Technology : the Journal of the American Association for Aerosol Research 58, no. 11 (2025). https://doi.org/10.1080/02786826.2024.2387135.

Kim, Yea Joon, et al. "Airborne Bacteria in Institutional and Commercial Buildings in Korea: Characterization With 16S RRNA Gene Sequencing and Association With Environmental Conditions." Aerosol Science and Technology : the Journal of the American Association for Aerosol Research, vol. 58, no. 11, 2025. Stacks. https://doi.org/10.1080/02786826.2024.2387135.
Export RIS Citation Information. TY - Journal Article AU - Kim, Yea Joon AU - Lee, Bong Gu AU - Shim, Joo Eun AU - Lee, Hyesoo AU - Park, Ju-Hyeong AU - Yeo, Min-Kyeong AB - Information on microorganisms in indoor air of various institutional and commercial buildings has significant value in a public health management perspective. However, there is a lack of prior research comparing indoor airborne microbiota across different categories of those buildings. We characterized indoor airborne bacteria in 10 buildings (two for each of five categories: train station, parking garage, mart, public library, and daycare center) during summer and winter. The 16S rRNA gene in the bacterial gDNA extracted from samples was quantified using quantitative real-time polymerase chain reaction and sequenced with the Illumina MiSeq AB - platform for characterizing community composition. We collected information on temperature, relative humidity, CO concentration, and particulate matter (PM) concentrations by particle size (<1μm, 1-2.5μm, 2.5-10μm) indoors. We performed a multivariate regression analysis to identify factors influencing bacterial quantity and Permutational Multivariate Analysis of Variance (PERMANOVA) to determine factors affecting cluster dissimilarity. We found that bacterial concentration was significantly (-values < 0.05) associated with season and CO concentration. The PERMANOVA analyses showed the significant (-values < 0.05) associations of bacterial cluster dissimilarity with season, building category, and CO. Our study indicated that the season, and CO concentrations may be important factors associated with the indoor airborne bacterial concentration and composition. Building category and usage appeared to significantly influence the bacterial community composition but not the concentration. Our study may provide basic data on bacterial community composition and their concentration that are needed for properly managing microbial exposures in occupants or customers of the studied institutional and commercial buildings. AB - Author manuscript AN - cdc:261571 C4 - PMC11926998 DO - https://doi.org/10.1080/02786826.2024.2387135 IS - 11 J2 - Aerosol Science and Technology : the Journal of the American Association for Aerosol Research KW - Humidity KW - Real-Time Polymerase Chain Reaction KW - Multivariate Analysis KW - Microbiota KW - Particle Size KW - Bacteria KW - Regression Analysis KW - Particulate Matter KW - RNA, Ribosomal, 16S KW - Air Pollution, Indoor KW - Temperature KW - Public Health KW - Genes, rRNA KW - Seasons KW - Indoor air KW - Bacteria KW - 16S rRNA KW - Building indoor air KW - DNA sequencing KW - Public-Use Facility KW - Air Pollution, Indoor KW - Genes, rRNA KW - Humidity KW - Particle Size KW - Public Health KW - RNA, Ribosomal, 16S KW - Real-Time Polymerase Chain Reaction KW - Seasons KW - Temperature KW - Multivariate Analysis KW - Regression Analysis KW - Particulate Matter KW - Microbiota KW - Bacteria LA - eng PY - 2025 T2 - Aerosol Science and Technology : the Journal of the American Association for Aerosol Research T2 - Aerosol Science and Technology : the Journal of the American Association for Aerosol Research, 2025, v. 58, no. 11 TI - Airborne Bacteria in Institutional and Commercial Buildings in Korea: Characterization With 16S RRNA Gene Sequencing and Association With Environmental Conditions. VL - 58 UR - https://stacks.cdc.gov/view/cdc/261571 ER -
Capturing and Converting co Using Amino Acids as Various Commercially Valuable Nano-carbonates.

Li, Qingyang ;

Qian, Yong

July 2025 | Separation and Purification Technology, 2025, v. 361, no. 1

Carbon dioxide (CO2) is the most significant greenhouse gas and one of the strategies to reduce CO2 emission is to convert CO2 into commercially valuable products. Currently, methods that can effectively capture and convert CO2 into carbonate nanomaterials, which have unique applications in various fields, have rarely been reported, and there are n ...

10/09/2026

Supporting Files

Title : Capturing and Converting co Using Amino Acids as Various Commercially Valuable Nano-carbonates. Personal Author(s) : Li, Qingyang;Qian, Yong;Xing, Malcolm;Li, Bingyun; Published Date : July 2025 Pages in Document : 131207(25 pdf pages) Source : Separation and Purification Technology, 2025, v. 361, no. 1 DOI : https://doi.org/10.1016/j.seppur.2024.131207 Journal Title : Separation and Purification Technology
Li, Q., Qian, Y., Xing, M., & Li, B. (2025). Capturing and Converting co Using Amino Acids as Various Commercially Valuable Nano-carbonates. Separation and Purification Technology, 361(1). https://doi.org/10.1016/j.seppur.2024.131207

Li, Qingyang, Yong Qian, Malcolm Xing, and Bingyun Li. "Capturing and Converting co Using Amino Acids as Various Commercially Valuable Nano-carbonates." Separation and Purification Technology 361, no. 1 (2025). https://doi.org/10.1016/j.seppur.2024.131207.

Li, Qingyang, et al. "Capturing and Converting co Using Amino Acids as Various Commercially Valuable Nano-carbonates." Separation and Purification Technology, vol. 361, no. 1, 2025. Stacks. https://doi.org/10.1016/j.seppur.2024.131207.
Export RIS Citation Information. TY - Journal Article AU - Li, Qingyang AU - Qian, Yong AU - Xing, Malcolm AU - Li, Bingyun AB - Carbon dioxide (CO2) is the most significant greenhouse gas and one of the strategies to reduce CO2 emission is to convert CO2 into commercially valuable products. Currently, methods that can effectively capture and convert CO2 into carbonate nanomaterials, which have unique applications in various fields, have rarely been reported, and there are no universal methods that can capture and convert CO2 into different nano-carbonates. In this study, an innovative two-step strategy based on amino acids was developed to produce multiple different carbonate nanoparticles, including CaCO3, BaCO3, and Ag2CO3 nanoparticles with diameters of 70 nm, 50 nm, and 7 nm, respectively. Fundamentally important, the nuclear magnetic resonance data clearly demonstrated that it was the amino acids (e.g., glycine) that dictated the formation of carbonate nanoparticles. In the presence of amino acids, a competition in forming nanoparticles and microparticles was observed, and the formation of nanoparticles was proportional to the carbamate formed from CO2 reacting with amino acids. In the absence of amino acids, carbonate microparticles (~ 2 μm) were formed. AB - Author manuscript AN - cdc:261570 C4 - PMC11926997 DO - https://doi.org/10.1016/j.seppur.2024.131207 IS - 1 J2 - Separation and Purification Technology KW - Carbonates KW - Calcium Carbonate KW - Magnetic Resonance Spectroscopy KW - Nanostructures KW - Greenhouse Gases KW - Nanoparticles KW - Amino Acids KW - Glycine KW - Carbon Dioxide KW - Carbamates KW - Carbon dioxide KW - Amino acid KW - Nano-carbonate KW - Nanoparticle KW - Carbon Dioxide KW - Greenhouse Gases KW - Magnetic Resonance Spectroscopy KW - Nanostructures KW - Nanoparticles KW - Amino Acids KW - Carbamates KW - Carbonates KW - Glycine KW - Calcium Carbonate LA - eng PY - 2025 T2 - Separation and Purification Technology T2 - Separation and Purification Technology, 2025, v. 361, no. 1 TI - Capturing and Converting co Using Amino Acids as Various Commercially Valuable Nano-carbonates. VL - 361 UR - https://stacks.cdc.gov/view/cdc/261570 ER -
Geosocial-networking App Use Among Men Who Have Sex With Men in High HIV Community Viral Load Areas of Baltimore City.

Fields, Errol L. ;

Evans, Kimberly N.

July 2025 | AIDS and Behavior, 2025, v. 29, no. 7

Geosocial networking applications (GSN apps) are important tools for HIV/sexually transmitted infection prevention among men who have sex with men (MSM). Strategies for identifying high transmission and acquisition among GSN app users are needed to prioritize public health response. Community viral load (CVL) is associated with HIV transmission and ...

10/09/2026

Supporting Files

Title : Geosocial-networking App Use Among Men Who Have Sex With Men in High HIV Community Viral Load Areas of Baltimore City. Personal Author(s) : Fields, Errol L.;Evans, Kimberly N.;Liu, Yang;Thornton, Nicole;Long, Amanda;Uzzi, Mudia;Gaul, Zaneta;Buchacz, Kate;King, Hope;Jennings, Jacky M.; Published Date : July 2025 Pages in Document : 2125-2134 (18 pdf pages) Source : AIDS and Behavior, 2025, v. 29, no. 7 DOI : https://doi.org/10.1007/s10461-025-04676-0 Journal Title : AIDS and Behavior
Fields, E. L., Evans, K. N., Liu, Y., Thornton, N., Long, A., Uzzi, M., Gaul, Z., Buchacz, K., King, H., & Jennings, J. M. (2025). Geosocial-networking App Use Among Men Who Have Sex With Men in High HIV Community Viral Load Areas of Baltimore City. AIDS and Behavior, 29(7). https://doi.org/10.1007/s10461-025-04676-0

Fields, Errol L., Kimberly N. Evans, Yang Liu, Nicole Thornton, Amanda Long, Mudia Uzzi, Zaneta Gaul, Kate Buchacz, Hope King, and Jacky M. Jennings. "Geosocial-networking App Use Among Men Who Have Sex With Men in High HIV Community Viral Load Areas of Baltimore City." AIDS and Behavior 29, no. 7 (2025). https://doi.org/10.1007/s10461-025-04676-0.

Fields, Errol L., et al. "Geosocial-networking App Use Among Men Who Have Sex With Men in High HIV Community Viral Load Areas of Baltimore City." AIDS and Behavior, vol. 29, no. 7, 2025. Stacks. https://doi.org/10.1007/s10461-025-04676-0.
Export RIS Citation Information. TY - Journal Article AU - Fields, Errol L. AU - Evans, Kimberly N. AU - Liu, Yang AU - Thornton, Nicole AU - Long, Amanda AU - Uzzi, Mudia AU - Gaul, Zaneta AU - Buchacz, Kate AU - King, Hope AU - Jennings, Jacky M. AB - Geosocial networking applications (GSN apps) are important tools for HIV/sexually transmitted infection prevention among men who have sex with men (MSM). Strategies for identifying high transmission and acquisition among GSN app users are needed to prioritize public health response. Community viral load (CVL) is associated with HIV transmission and can be used to identify populations with behaviors/environment associated with HIV/STI risk. We sought to determine user profile characteristics and utilization patterns associated with GSN app use in high CVL census tracts (CT). We used routine HIV surveillance data from in-care individuals and their viral loads at the point of diagnosis to estimate CVL in 200 CTs across Baltimore City. CTs were ordered based on CVL and categorized into quantiles from high to low. Among GSN user profiles, multiple imputation methods were used to complete missing profile characteristics. We then used imputed datasets to explore the association between profile characteristics, app utilization times, and app use in high CVL CTs using a Poisson regression model with robust error variances. Data on 606 profiles were collected originally and imputed 50 times to create a complete data set for analysis. GSN app users were aged 18-65 years [mean = 33.9, 95% confidence interval (CI): 33.1-34.7], with 52.2% Black (95% CI: 47.9- 56.5%), 6.8% living with HIV (95% CI: 4.4- 9.2%), 39.1% in high CVL CTs (95% CI: 35.2- 43.0%), 50.6% use at nighttime (95% CI: 46.7- 54.6%) and 51.6% use during the weekend (95% CI: 47.6- 55.6%). Black MSM users [Relative risk (RR) = 1.12, 95% CI: 1.04-1.20] were associated with GSN app use in high CVL CTs. MSM with profiles listing versatile sex position preference (RR = 1.12, 95% CI: 1.02-1.23) and profiles listing top sex position preference (RR = 1.13, 95% CI: 1.03-1.23) were associated with GSN app use in high and medium CVL CTs. GSN app user profiles of people in high and medium CVL CTs, especially Black MSM and those who report top and versatile sexual positions, may benefit from online prevention messages and real-time notification of health resources presently available in their communities to reduce HIV transmission. AB - Author manuscript AN - cdc:261569 C4 - PMC12229753 DO - https://doi.org/10.1007/s10461-025-04676-0 IS - 7 J2 - AIDS and Behavior KW - Adolescent KW - Mobile Applications KW - Social Networking KW - Young Adult KW - Homosexuality, Male KW - Risk-Taking KW - Male KW - Humans KW - Middle Aged KW - Adult KW - HIV Infections KW - Sexual Behavior KW - Viral Load KW - HIV KW - Community viral load KW - Geo-social networking apps KW - Mobile app KW - Dating apps KW - Men who have sex with men KW - African american KW - Humans KW - Male KW - HIV Infections KW - Adult KW - Homosexuality, Male KW - Mobile Applications KW - Viral Load KW - Middle Aged KW - Young Adult KW - Adolescent KW - Social Networking KW - Sexual Behavior KW - Risk-Taking LA - eng PY - 2025 T2 - AIDS and Behavior T2 - AIDS and Behavior, 2025, v. 29, no. 7 TI - Geosocial-networking App Use Among Men Who Have Sex With Men in High HIV Community Viral Load Areas of Baltimore City. VL - 29 UR - https://stacks.cdc.gov/view/cdc/261569 ER -
Strengths and Limitations of Non-survey-based Data Sources For Assessing Adult Vaccination Coverage in the United States.

Daley, Matthew F. ;

Homdayjanakul, Kamonthip J.

December 2025 | Expert Review of Vaccines, 2025, v. 24, no. 1

Non-survey-based data sources (e.g. electronic health records, administrative claims) have been used to estimate vaccination coverage among US adults. However, these data sources were not collected for research or surveillance purposes and may have substantial limitations. The objectives of this narrative review were to: 1) identify published studi ...

10/09/2026

Supporting Files

Title : Strengths and Limitations of Non-survey-based Data Sources For Assessing Adult Vaccination Coverage in the United States. Personal Author(s) : Daley, Matthew F.;Homdayjanakul, Kamonthip J.;Hurley, Laura P.;Lu, Peng-Jun;Tsai, Yuping;Black, Carla L.;Patel, Suchita;Singleton, James A.;Crane, Lori A.; Published Date : December 2025 Pages in Document : 230-241 (23 pdf pages) Source : Expert Review of Vaccines, 2025, v. 24, no. 1 DOI : https://doi.org/10.1080/14760584.2025.2483719 Journal Title : Expert Review of Vaccines
Daley, M. F., Homdayjanakul, K. J., Hurley, L. P., Lu, P. J., Tsai, Y., Black, C. L., Patel, S., Singleton, J. A., & Crane, L. A. (2025). Strengths and Limitations of Non-survey-based Data Sources For Assessing Adult Vaccination Coverage in the United States. Expert Review of Vaccines, 24(1). https://doi.org/10.1080/14760584.2025.2483719

Daley, Matthew F., Kamonthip J. Homdayjanakul, Laura P. Hurley, Peng-Jun Lu, Yuping Tsai, Carla L. Black, Suchita Patel, James A. Singleton, and Lori A. Crane. "Strengths and Limitations of Non-survey-based Data Sources For Assessing Adult Vaccination Coverage in the United States." Expert Review of Vaccines 24, no. 1 (2025). https://doi.org/10.1080/14760584.2025.2483719.

Daley, Matthew F., et al. "Strengths and Limitations of Non-survey-based Data Sources For Assessing Adult Vaccination Coverage in the United States." Expert Review of Vaccines, vol. 24, no. 1, 2025. Stacks. https://doi.org/10.1080/14760584.2025.2483719.
Export RIS Citation Information. TY - Journal Article AU - Daley, Matthew F. AU - Homdayjanakul, Kamonthip J. AU - Hurley, Laura P. AU - Lu, Peng-Jun AU - Tsai, Yuping AU - Black, Carla L. AU - Patel, Suchita AU - Singleton, James A. AU - Crane, Lori A. AB - Non-survey-based data sources (e.g. electronic health records, administrative claims) have been used to estimate vaccination coverage among US adults. However, these data sources were not collected for research or surveillance purposes and may have substantial limitations. The objectives of this narrative review were to: 1) identify published studies that used non-survey-based data sources to estimate adult vaccination coverage for one or more routinely recommended vaccines; and 2) summarize the strengths and limitations of these data sources for coverage assessments. AB - Thirty-four publications derived from 9 data sources were reviewed: 16 publications were in a general population (i.e. defined by age), 12 were among pregnant women, and 6 were among individuals with chronic health conditions. While several data sources used continuous health insurance enrollment to define the study population, doing so limited generalizability to stably insured populations. Methods for obtaining race and ethnicity data were complex and potentially subject to bias. None of the reviewed studies presented any formal assessment of vaccine data validity. AB - While multiple non-survey-based data sources have been used to assess adult vaccination coverage in the United States, important limitations exist, including related to generalizability, data validity, and risk of bias. AB - Author manuscript AN - cdc:261568 C4 - PMC12083505 DO - https://doi.org/10.1080/14760584.2025.2483719 IS - 1 J2 - Expert Review of Vaccines KW - Pregnancy KW - Female KW - Vaccination KW - Vaccines KW - Information Sources KW - Electronic Health Records KW - Humans KW - Vaccination Coverage KW - Adult KW - Adult vaccination KW - immunization KW - vaccine KW - surveillance KW - coverage KW - Humans KW - Vaccination Coverage KW - Adult KW - Vaccines KW - Female KW - Vaccination KW - Pregnancy KW - Electronic Health Records KW - Information Sources LA - eng PY - 2025 T2 - Expert Review of Vaccines T2 - Expert Review of Vaccines, 2025, v. 24, no. 1 TI - Strengths and Limitations of Non-survey-based Data Sources For Assessing Adult Vaccination Coverage in the United States. VL - 24 UR - https://stacks.cdc.gov/view/cdc/261568 ER -
COVID-19 and Completion of Select Routine Childhood Vaccinations.

DeSilva, Malini B. ;

Haapala, Jacob

April 2025 | Pediatrics, 2025, v. 155, no. 4

To evaluate rotavirus (RV), diphtheria, tetanus, and acellular pertussis (DTaP), and pneumococcal conjugate vaccine (PCV) vaccine coverage and factors associated with vaccine uptake from 2018 through 2023.We included infants born between January 1, 2018 and May 31, 2023, with a minimum of 9 months of enrollment in the first 12 months of life and at ...

10/09/2026

Supporting Files

Title : COVID-19 and Completion of Select Routine Childhood Vaccinations. Personal Author(s) : DeSilva, Malini B.;Haapala, Jacob;Vazquez-Benitez, Gabriela;Daley, Matthew F.;Lewin, Bruno;Klein, Nicola P.;Liles, Elizabeth G.;Jackson, Lisa A.;Williams, Joshua T.B.;Donahue, James G.;Yih, W. Katherine;Kharbanda, Elyse O.; Published Date : April 2025 Pages in Document : e2024068244(17 pdf pages) Source : Pediatrics, 2025, v. 155, no. 4 DOI : https://doi.org/10.1542/peds.2024-068244 Journal Title : Pediatrics
DeSilva, M. B., Haapala, J., Vazquez-Benitez, G., Daley, M. F., Lewin, B., Klein, N. P., Liles, E. G., Jackson, L. A., Williams, J. T., Donahue, J. G., Yih, W. K., & Kharbanda, E. O. (2025). COVID-19 and Completion of Select Routine Childhood Vaccinations. Pediatrics, 155(4). https://doi.org/10.1542/peds.2024-068244

DeSilva, Malini B., Jacob Haapala, Gabriela Vazquez-Benitez, Matthew F. Daley, Bruno Lewin, Nicola P. Klein, and Elizabeth G. Liles, et al.. "COVID-19 and Completion of Select Routine Childhood Vaccinations." Pediatrics 155, no. 4 (2025). https://doi.org/10.1542/peds.2024-068244.

DeSilva, Malini B., et al. "COVID-19 and Completion of Select Routine Childhood Vaccinations." Pediatrics, vol. 155, no. 4, 2025. Stacks. https://doi.org/10.1542/peds.2024-068244.
Export RIS Citation Information. TY - Journal Article AU - DeSilva, Malini B. AU - Haapala, Jacob AU - Vazquez-Benitez, Gabriela AU - Daley, Matthew F. AU - Lewin, Bruno AU - Klein, Nicola P. AU - Liles, Elizabeth G. AU - Jackson, Lisa A. AU - Williams, Joshua T.B. AU - Donahue, James G. AU - Yih, W. Katherine AU - Kharbanda, Elyse O. AB - To evaluate rotavirus (RV), diphtheria, tetanus, and acellular pertussis (DTaP), and pneumococcal conjugate vaccine (PCV) vaccine coverage and factors associated with vaccine uptake from 2018 through 2023. AB - We included infants born between January 1, 2018 and May 31, 2023, with a minimum of 9 months of enrollment in the first 12 months of life and at least 1 medical visit between 9 and 12 months at 1 of 8 Vaccine Safety Datalink health systems. We evaluated coverage with 2 doses of RV, DTaP, and PCV vaccines at 5 months and completion of recommended doses by 12 months. We evaluated associations of patient race, ethnicity, caregiver's primary language, Medicaid, and time period with vaccine uptake. AB - We included 395 143 infants: 48.4% female; 14.7% non-Hispanic Asian; 5.8% non-Hispanic Black; 34.2% Hispanic; and 20.6% with Medicaid. Coverage for 2 doses of all 3 vaccines at 5 months was 87.8% (95% CI 86.9-88.7) in February 2020 vs 80.8% (95% CI 79.8-81.8) in October 2023. Vaccine series completion at 12 months was highest in January 2020 with 92.3% (95% CI 91.6-92.9) vs 89.6% (95% CI 88.8-90.3) in October 2023. Factors associated with lower vaccine uptake included having a caregiver whose primary language was not English or Spanish, non-Hispanic Black race, and Medicaid. AB - Over 3 years after the COVID-19 pandemic started, coverage for selected routine childhood immunizations remained below prepandemic levels. Demographic factors, which may reflect structural barriers to accessing care, likely affected coverage. Focused interventions are needed to improve vaccine coverage in all populations. AB - Author manuscript AN - cdc:261567 C4 - PMC13186266 DO - https://doi.org/10.1542/peds.2024-068244 IS - 4 J2 - Pediatrics KW - Rotavirus Vaccines KW - Female KW - Vaccination KW - Infant KW - Diphtheria-Tetanus-acellular Pertussis Vaccines KW - Male KW - Humans KW - Infant, Newborn KW - COVID-19 KW - Vaccination Coverage KW - Medicaid KW - Pneumococcal Vaccines KW - Humans KW - Female KW - Male KW - Infant KW - COVID-19 KW - Vaccination Coverage KW - Rotavirus Vaccines KW - Pneumococcal Vaccines KW - Diphtheria-Tetanus-acellular Pertussis Vaccines KW - Vaccination KW - Medicaid KW - Infant, Newborn LA - eng PY - 2025 T2 - Pediatrics T2 - Pediatrics, 2025, v. 155, no. 4 TI - COVID-19 and Completion of Select Routine Childhood Vaccinations. VL - 155 UR - https://stacks.cdc.gov/view/cdc/261567 ER -
An Examination of Facilitators and Barriers to Care Receipt Among Specific Groups of LGBTQ+ and Cisgender Heterosexual Veterans.

Upham, Michelle ;

Beaver, Kristine

January 1, 2026 | Psychology of Sexual Orientation and Gender Diversity, January 2026

The present study examined rates and factors associated with past-year Veterans Health Administration (VHA) overall healthcare utilization and VA mental health treatment among LGBTQ+ and cisgender heterosexual veterans. Baseline data from a national longitudinal study of LGBTQ+ and cisgender heterosexual veteran VHA users and non-users (N = 1,062) ...

10/09/2026

Supporting Files

Title : An Examination of Facilitators and Barriers to Care Receipt Among Specific Groups of LGBTQ+ and Cisgender Heterosexual Veterans. Personal Author(s) : Upham, Michelle;Beaver, Kristine;Chang, Cindy J.;Cascalheira, Cory J.;Rhew, Isaac C.;DeFiori, Kim;Dashtestani, Krista S.;Kauth, Michael R.;Shipherd, Jillian C.;Kaysen, Debra;Simpson, Tracy L.; Published Date : January 1, 2026 Pages in Document : 34 pdf pages Source : Psychology of Sexual Orientation and Gender Diversity, January 2026 DOI : https://doi.org/10.1037/sgd0000820 Journal Title : Psychology of Sexual Orientation and Gender Diversity
Upham, M., Beaver, K., Chang, C. J., Cascalheira, C. J., Rhew, I. C., DeFiori, K., Dashtestani, K. S., Kauth, M. R., Shipherd, J. C., Kaysen, D., & Simpson, T. L. (2026). An Examination of Facilitators and Barriers to Care Receipt Among Specific Groups of LGBTQ+ and Cisgender Heterosexual Veterans. Psychology of Sexual Orientation and Gender Diversity. https://doi.org/10.1037/sgd0000820

Upham, Michelle, Kristine Beaver, Cindy J. Chang, Cory J. Cascalheira, Isaac C. Rhew, Kim DeFiori, and Krista S. Dashtestani, et al.. "An Examination of Facilitators and Barriers to Care Receipt Among Specific Groups of LGBTQ+ and Cisgender Heterosexual Veterans." Psychology of Sexual Orientation and Gender Diversity (2026). https://doi.org/10.1037/sgd0000820.

Upham, Michelle, et al. "An Examination of Facilitators and Barriers to Care Receipt Among Specific Groups of LGBTQ+ and Cisgender Heterosexual Veterans." Psychology of Sexual Orientation and Gender Diversity, 2026. Stacks. https://doi.org/10.1037/sgd0000820.
Export RIS Citation Information. TY - Journal Article AU - Upham, Michelle AU - Beaver, Kristine AU - Chang, Cindy J. AU - Cascalheira, Cory J. AU - Rhew, Isaac C. AU - DeFiori, Kim AU - Dashtestani, Krista S. AU - Kauth, Michael R. AU - Shipherd, Jillian C. AU - Kaysen, Debra AU - Simpson, Tracy L. AB - The present study examined rates and factors associated with past-year Veterans Health Administration (VHA) overall healthcare utilization and VA mental health treatment among LGBTQ+ and cisgender heterosexual veterans. Baseline data from a national longitudinal study of LGBTQ+ and cisgender heterosexual veteran VHA users and non-users (N = 1,062) were used in generalized linear models to estimate the predicted prevalence of VHA healthcare utilization for each LGBTQ+ and cisgender subgroup, stratified by gender. Additional multivariable regressions were guided by the Andersen health services utilization model. There were no significant differences in healthcare utilization among women subgroups. Among men subgroups, cisgender gay men had lower predicted prevalence of VHA utilization than cisgender heterosexual and transgender men. In both the women's and men's models, VHA eligibility indicators and perceived lack of service availability were associated with increased odds for any past-year utilization; higher income, difficulty understanding eligibility/benefits, and logistical barriers were associated with decreased odds. Lifetime harassment at VHA was positively associated with past-year overall VHA utilization in women's models. LGBTQ+ specific factors explained significant variance in some models while transgender/gender diverse specific needs did not. These findings suggest that veterans generally need assistance navigating VHA eligibility issues and that LGBTQ+ veterans would benefit from systemic attention to provider sensitivity and availability of services focused on their needs. The high rates of harassment reported across women subgroups (19% to 25%) and by transgender men (38%) warrant institution-wide action. AB - Author manuscript AN - cdc:261566 C4 - PMC11931685 DO - https://doi.org/10.1037/sgd0000820 J2 - Psychology of Sexual Orientation and Gender Diversity KW - Veterans KW - Linear Models KW - Longitudinal Studies KW - Veterans Health KW - Heterosexuality KW - Prevalence KW - Facilities and Services Utilization KW - Transgender Persons KW - Mental Health KW - Patient Acceptance of Health Care KW - healthcare utilization KW - military KW - sexual minority KW - gender minority KW - veterans KW - Facilities and Services Utilization KW - Heterosexuality KW - Linear Models KW - Longitudinal Studies KW - Mental Health KW - Prevalence KW - Transgender Persons KW - Veterans KW - Veterans Health KW - Patient Acceptance of Health Care LA - eng PY - 2026 T2 - Psychology of Sexual Orientation and Gender Diversity T2 - Psychology of Sexual Orientation and Gender Diversity, January 2026 TI - An Examination of Facilitators and Barriers to Care Receipt Among Specific Groups of LGBTQ+ and Cisgender Heterosexual Veterans. UR - https://stacks.cdc.gov/view/cdc/261566 ER -
New Insights on Transmission of Sporothrix Brasiliensis.

Cognialli, Regielly C. R. ;

Queiroz-Telles, Flávio

March 2025 | Mycoses, 2025, v. 68, no. 3

Sporotrichosis is the most prevalent saprozoonotic implantation mycosis worldwide.A prospective experimental study was performed to evaluate persistence on surfaces such as stainless steel medium-density fiberboard (MDF) wood, tile, and polyester fabric.The different surfaces were homogeneously contaminated using the yeast phase of Sporothrix brasi ...

10/09/2026

Supporting Files

Title : New Insights on Transmission of Sporothrix Brasiliensis. Personal Author(s) : Cognialli, Regielly C. R.;Queiroz-Telles, Flávio;Cavanaugh, Alyson M.;Rediguieri, Bruno C.;Santos, Giovanna C. D.;Matias, Felipe Moreira;Filho, Luciano Moreira;Monteiro Neto, Elias N.;Surek, Mônica;Vicente, Vânia A.;Santos-Weiss, Izabella C. R.; Published Date : March 2025 Pages in Document : e70047 (12 pdf pages) Source : Mycoses, 2025, v. 68, no. 3 DOI : https://doi.org/10.1111/myc.70047 Journal Title : Mycoses
Cognialli, R. C. R., Queiroz-Telles, F., Cavanaugh, A. M., Rediguieri, B. C., Santos, G. C. D., Matias, F. M., Filho, L. M., Monteiro Neto, E. N., Surek, M., Vicente, V. A., & Santos-Weiss, I. C. R. (2025). New Insights on Transmission of Sporothrix Brasiliensis. Mycoses, 68(3). https://doi.org/10.1111/myc.70047

Cognialli, Regielly C. R., Flávio Queiroz-Telles, Alyson M. Cavanaugh, Bruno C. Rediguieri, Giovanna C. D. Santos, Felipe Moreira Matias, and Luciano Moreira Filho, et al.. "New Insights on Transmission of Sporothrix Brasiliensis." Mycoses 68, no. 3 (2025). https://doi.org/10.1111/myc.70047.

Cognialli, Regielly C. R., et al. "New Insights on Transmission of Sporothrix Brasiliensis." Mycoses, vol. 68, no. 3, 2025. Stacks. https://doi.org/10.1111/myc.70047.
Export RIS Citation Information. TY - Journal Article AU - Cognialli, Regielly C. R. AU - Queiroz-Telles, Flávio AU - Cavanaugh, Alyson M. AU - Rediguieri, Bruno C. AU - Santos, Giovanna C. D. AU - Matias, Felipe Moreira AU - Filho, Luciano Moreira AU - Monteiro Neto, Elias N. AU - Surek, Mônica AU - Vicente, Vânia A. AU - Santos-Weiss, Izabella C. R. AB - Sporotrichosis is the most prevalent saprozoonotic implantation mycosis worldwide. AB - A prospective experimental study was performed to evaluate persistence on surfaces such as stainless steel medium-density fiberboard (MDF) wood, tile, and polyester fabric. AB - The different surfaces were homogeneously contaminated using the yeast phase of Sporothrix brasiliensis. Fungal culture was carried out in triplicate on Mycosel agar, at time 0 and then every 24 h, until 792 h (33 days). AB - Sporothrix brasiliensis persists on MDF wood for up to 240 h (10 days), tile for 288 h (12 days), polyester fabric for 384 h (16 days), and stainless steel for up to 600 h (25 days). AB - Based on these findings, in concordance with published clinical reports suggesting fomite transmission, we propose an updated schematic of S. brasiliensis transmission. This is the first in vitro study about the persistence of S. brasiliensis on different surfaces, which is essential to understand transmission routes for a One Health Approach. AB - Author manuscript AN - cdc:261565 C4 - PMC12432969 DO - https://doi.org/10.1111/myc.70047 IS - 3 J2 - Mycoses KW - Wood KW - Textiles KW - Sporotrichosis KW - Stainless Steel KW - Animals KW - Polyesters KW - Mycoses KW - Sporothrix KW - Humans KW - Fomites KW - Time Factors KW - non-zoonotic fomites KW - persistence KW - sapronotic KW - sporotrichosis KW - transmission KW - zoonotic KW - Fomites KW - Mycoses KW - Polyesters KW - Sporothrix KW - Sporotrichosis KW - Stainless Steel KW - Textiles KW - Time Factors KW - Wood KW - Humans KW - Animals LA - eng PY - 2025 T2 - Mycoses T2 - Mycoses, 2025, v. 68, no. 3 TI - New Insights on Transmission of Sporothrix Brasiliensis. VL - 68 UR - https://stacks.cdc.gov/view/cdc/261565 ER -
Behavioral Fluctuation in Disorders of Consciousness: a Retrospective Analysis.

Barra, Alice ;

Bodien, Yelena G

October 2025 | Archives of Physical Medicine and Rehabilitation, 2025, v. 106, no. 10

To assess the frequency of behavioral fluctuations in patients with prolonged disorders of consciousness (DoC), characterize the stability of consciousness ratings, and characterize the stability of behavioral signs of consciousness.Prospective observational analysis.Specialized DoC program in an inpatient rehabilitation facility and a long-term ac ...

10/09/2026

Supporting Files

Title : Behavioral Fluctuation in Disorders of Consciousness: a Retrospective Analysis. Personal Author(s) : Barra, Alice;Bodien, Yelena G;Tan, Can Ozan;Martens, Geraldine;Malone, Christopher;Giacino, Joseph T; Published Date : October 2025 Pages in Document : 1505-1513 (21 pdf pages) Source : Archives of Physical Medicine and Rehabilitation, 2025, v. 106, no. 10 DOI : https://doi.org/10.1016/j.apmr.2025.03.038 Journal Title : Archives of Physical Medicine and Rehabilitation
Barra, A., Bodien, Y. G., Tan, C. O., Martens, G., Malone, C., & Giacino, J. T. (2025). Behavioral Fluctuation in Disorders of Consciousness: a Retrospective Analysis. Archives of Physical Medicine and Rehabilitation, 106(10). https://doi.org/10.1016/j.apmr.2025.03.038

Barra, Alice, Yelena G Bodien, Can Ozan Tan, Geraldine Martens, Christopher Malone, and Joseph T Giacino. "Behavioral Fluctuation in Disorders of Consciousness: a Retrospective Analysis." Archives of Physical Medicine and Rehabilitation 106, no. 10 (2025). https://doi.org/10.1016/j.apmr.2025.03.038.

Barra, Alice, et al. "Behavioral Fluctuation in Disorders of Consciousness: a Retrospective Analysis." Archives of Physical Medicine and Rehabilitation, vol. 106, no. 10, 2025. Stacks. https://doi.org/10.1016/j.apmr.2025.03.038.
Export RIS Citation Information. TY - Journal Article AU - Barra, Alice AU - Bodien, Yelena G AU - Tan, Can Ozan AU - Martens, Geraldine AU - Malone, Christopher AU - Giacino, Joseph T AB - To assess the frequency of behavioral fluctuations in patients with prolonged disorders of consciousness (DoC), characterize the stability of consciousness ratings, and characterize the stability of behavioral signs of consciousness. AB - Prospective observational analysis. AB - Specialized DoC program in an inpatient rehabilitation facility and a long-term acute care hospital. AB - Patients in a vegetative state/unresponsive wakefulness state, minimally conscious state, and emerging from a minimally conscious state followed weekly by the Coma Recovery Scale-Revised (CRS-R) between 28 and 90days postinjury (N=241). AB - Change in CRS-R subscale scores and consciousness ratings. AB - Behavioral fluctuation was observed in >80% of patients and was most common in the CRS-R motor subscale and least common in the communication subscale (83% and 54% of patients experienced ≥1 fluctuation over the 3wk study period, respectively, with a 1-point change observed most frequently). Among patients who were conscious at baseline assessment, 25% were subsequently rated as unconscious at least once. Localization to pain and object manipulation were the most stable signs of consciousness, recurring at least 3 times after the first occurrence in ≥97% of the sample. Reproducible command-following and intelligible verbalization were the least stable, recurring at least 3 times after the first occurrence in ≤27% of the sample. AB - Patients with prolonged DoC who undergo serial assessment demonstrate a high rate of fluctuation in behavioral signs of consciousness. These findings highlight that repeated assessments are essential in this population, both to capture the highest level of consciousness and to help distinguish spontaneous fluctuation from response to treatment in interventional studies. AB - Author manuscript AN - cdc:261564 C4 - PMC12353754 DO - https://doi.org/10.1016/j.apmr.2025.03.038 IS - 10 J2 - Archives of Physical Medicine and Rehabilitation KW - Retrospective Studies KW - Persistent Vegetative State KW - Consciousness Disorders KW - Female KW - Male KW - Prospective Studies KW - Aged KW - Humans KW - Middle Aged KW - Adult KW - Disorders of consciousness KW - assessment scale KW - traumatic brain injury KW - rehabilitation KW - minimally conscious state KW - vegetative state KW - unresponsive wakefulness syndrome KW - Humans KW - Male KW - Female KW - Middle Aged KW - Consciousness Disorders KW - Adult KW - Prospective Studies KW - Retrospective Studies KW - Aged KW - Persistent Vegetative State LA - eng PY - 2025 T2 - Archives of Physical Medicine and Rehabilitation T2 - Archives of Physical Medicine and Rehabilitation, 2025, v. 106, no. 10 TI - Behavioral Fluctuation in Disorders of Consciousness: a Retrospective Analysis. VL - 106 UR - https://stacks.cdc.gov/view/cdc/261564 ER -

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