Recent Additions

This page includes the documents that were newly added to the repository within the last 30 days.

All these words:

This exact word or phrase:

Any of these words:

None of these words:

Language:

Publication Date Range:

Visit our Help Page for additional assistance

Select a Range:

Select a Format:

Custom Search Builder:

Custom Search Box

Visit our Help Page for additional assistance

Showing 261 - 280 of 797 results

Longitudinal Associations of Job Demand-Control Characteristics with Objective and Subjective Cognitive Outcomes in Older Workers: The Health and Retirement Study

Guardiano, Megan ;

Andel, Ross

2025/12/01 | Am J Ind Med 2025 Dec; 68(12):1115-1130 | National Institute for Occupational Safety and Health (NIOSH)

Background: The job demand-control (JDC) psychosocial work model has demonstrated effects on objective cognitive performance, but its association with subjective memory is still poorly understood. We examined longitudinal associations of JDC characteristics with objective (general cognitive function/episodic memory) and subjective (perceived memory ...

08/10/2026

Title : Longitudinal Associations of Job Demand-Control Characteristics with Objective and Subjective Cognitive Outcomes in Older Workers: The Health and Retirement Study Personal Author(s) : Guardiano, Megan;Andel, Ross;Trudel, Xavier;Li, Jian; Published Date : 2025/12/01 Pages in Document : 16 pdf pages Source : Am J Ind Med 2025 Dec; 68(12):1115-1130 URL : https://stacks.cdc.gov/view/cdc/258728 Journal Title : American Journal of Industrial Medicine
Guardiano, Megan et al. (2025). Longitudinal Associations of Job Demand-Control Characteristics with Objective and Subjective Cognitive Outcomes in Older Workers: The Health and Retirement Study. American Journal of Industrial Medicine. 68

Guardiano, Megan et al. "Longitudinal Associations of Job Demand-Control Characteristics with Objective and Subjective Cognitive Outcomes in Older Workers: The Health and Retirement Study" American Journal of Industrial Medicine 68 (2025)

Guardiano, Megan et al. "Longitudinal Associations of Job Demand-Control Characteristics with Objective and Subjective Cognitive Outcomes in Older Workers: The Health and Retirement Study" American Journal of Industrial Medicine, vol. 68, 2025
Export RIS Citation Information. TY - Journal Article AU - Guardiano, Megan AU - Andel, Ross AU - Trudel, Xavier AU - Li, Jian AB - Background: The job demand-control (JDC) psychosocial work model has demonstrated effects on objective cognitive performance, but its association with subjective memory is still poorly understood. We examined longitudinal associations of JDC characteristics with objective (general cognitive function/episodic memory) and subjective (perceived memory) cognition. Methods: Using the Health and Retirement Study (HRS) data, 3497 workers aged 50+ were followed from 2006-2008 to 2018. Self-reported job demand and job control were dichotomized and later combined into quadrants reflecting high/low job strain and active/passive jobs. Analyses used covariate-adjusted generalized estimating equations. Results: High job control was significantly positively associated with general cognitive function (regression coefficient: 0.409, p < 0.001), episodic memory (0.373, p < 0.001), and subjective memory (0.057, p = 0.034). "Low demand and high control" (low strain work) exhibited significant, positive associations with all cognitive outcomes. "High demand and high control" (active work) was significantly positively associated with objective cognitive outcomes. Conclusions: Opportunities for enhancing job control may promote objective cognition and subjective memory health in the US aging workforce. AN - cdc:258728 J2 - American Journal of Industrial Medicine KW - Aging KW - Surveys and Questionnaires KW - Safety KW - Cognition KW - Occupational Health KW - Longitudinal study; Aging workforce; Cognitive function; Job design; Population based studies; Questionnaires; KW - Author Keywords: cognition; job demand-control; older workers; psychosocial work; subjective memory KW - Aging KW - Cognition KW - Occupational Health KW - Safety KW - Surveys and Questionnaires PY - 2025/12/01 T2 - American Journal of Industrial Medicine T2 - Am J Ind Med 2025 Dec; 68(12):1115-1130 TI - Longitudinal Associations of Job Demand-Control Characteristics with Objective and Subjective Cognitive Outcomes in Older Workers: The Health and Retirement Study VL - 68 UR - https://stacks.cdc.gov/view/cdc/258728 ER -
Permeation of 2-Butoxyethanol Through Multiple Layers of a Disposable Nitrile Glove Material and a Single Layer of Microflex 93-260

Song Kuramoto, Eu Jin ;

Que Hee, Shane S.

2025/11/01 | Materials 2025 Nov; 18(21):5055 | National Institute for Occupational Safety and Health (NIOSH)

Double gloving of disposable gloves occurs in healthcare when extra protection is required against carcinogens, sensitizers, pathogens and sharps. Triple gloving is much rarer. The resistances of single, double and triple layers of disposable nitrile glove material against 2-butoxyethanol (2-BE) were compared with the resistance of a single layer o ...

08/10/2026

Title : Permeation of 2-Butoxyethanol Through Multiple Layers of a Disposable Nitrile Glove Material and a Single Layer of Microflex 93-260 Personal Author(s) : Song Kuramoto, Eu Jin;Que Hee, Shane S.; Published Date : 2025/11/01 Pages in Document : 11 pdf pages Source : Materials 2025 Nov; 18(21):5055 URL : https://stacks.cdc.gov/view/cdc/258727 Journal Title : Materials
Song Kuramoto, Eu Jin and Que Hee, Shane S. (2025). Permeation of 2-Butoxyethanol Through Multiple Layers of a Disposable Nitrile Glove Material and a Single Layer of Microflex 93-260. Materials. 18

Song Kuramoto, Eu Jin and Que Hee, Shane S. "Permeation of 2-Butoxyethanol Through Multiple Layers of a Disposable Nitrile Glove Material and a Single Layer of Microflex 93-260" Materials 18 (2025)

Song Kuramoto, Eu Jin and Que Hee, Shane S. "Permeation of 2-Butoxyethanol Through Multiple Layers of a Disposable Nitrile Glove Material and a Single Layer of Microflex 93-260" Materials, vol. 18, 2025
Export RIS Citation Information. TY - Journal Article AU - Song Kuramoto, Eu Jin AU - Que Hee, Shane S. AB - Double gloving of disposable gloves occurs in healthcare when extra protection is required against carcinogens, sensitizers, pathogens and sharps. Triple gloving is much rarer. The resistances of single, double and triple layers of disposable nitrile glove material against 2-butoxyethanol (2-BE) were compared with the resistance of a single layer of Microflex 93-260 (Microflex). Three 2.54 cm ASTM F739 permeation cells with closed-loop water collection without recirculation in a moving tray water bath at 35.0 +/- 0.5 degrees C facilitated the permeation relative to a blank cell. Capillary gas chromatography/mass spectrometry allowed the determination of the standardized breakthrough time (SBT), steady state permeation rate (SSPR) and cumulated permeated mass/area (CPM/A) by 30 min. Two nitrile layers (267 +/- 14 µm) were about the same thickness as the Microflex layer (249 +/- 6 µm). Statistical analysis showed equivalence at p ≤ 0.05 of the multiple layers and the Microflex layer relative to average SBT and CPM/A by 30 min, all such comparisons with the single nitrile layer also being statistically different. The triple layer had an average SSPR or post-breakthrough permeation rate 8 times lower than its single layer, while that for the Microflex layer was 1.5 times lower. Thus, the Microflex layer in terms of CPM/A by 30 min at 210 +/- 40 µg/cm2 appeared closer to two nitrile layers (520 +/- 560 µg/cm2) than three (93 +/- 93 µg/cm2). AN - cdc:258727 J2 - Materials KW - Safety KW - Occupational Health KW - Gloves KW - Nitriles KW - Materials testing; Gloves; 2-Butoxyethanol; Nitriles; Skin exposure; KW - Author Keywords: 2-butoxyethanol; disposable nitrile gloves; double and triple gloving; Microflex 93-260; permeation KW - Gloves KW - Nitriles KW - Occupational Health KW - Safety PY - 2025/11/01 T2 - Materials T2 - Materials 2025 Nov; 18(21):5055 TI - Permeation of 2-Butoxyethanol Through Multiple Layers of a Disposable Nitrile Glove Material and a Single Layer of Microflex 93-260 VL - 18 UR - https://stacks.cdc.gov/view/cdc/258727 ER -
A Cross-Sectional Legal Epidemiology Study of Associations Between State-Level Labor Laws (LLEI) and Workplace Sanitation and Training Indicators Among Hispanic US Crop Workers Using the National Agricultural Workers Survey (NAWS)

Santos, Chavez

;

Orenlas, India

2026/04/01 | J Occup Environ Med 2026 Apr; 68(4):e288-e294 | National Institute for Occupational Safety and Health (NIOSH)

Objective: Agricultural workers are at a disproportionate risk of work-related injuries and illnesses. We examined how labor laws are associated with agricultural workers' work environments. Methods: We conducted a cross-sectional study of Hispanic/Latine participants in the National Agricultural Workers Survey to assess the association between a L ...

08/10/2026

Title : A Cross-Sectional Legal Epidemiology Study of Associations Between State-Level Labor Laws (LLEI) and Workplace Sanitation and Training Indicators Among Hispanic US Crop Workers Using the National Agricultural Workers Survey (NAWS) Personal Author(s) : Santos, Chavez;Orenlas, India;Hill, Heather;Spector, June T.;Flunker, John C.;Baquero, Barbara; Published Date : 2026/04/01 Pages in Document : 7 pdf pages Source : J Occup Environ Med 2026 Apr; 68(4):e288-e294 URL : https://stacks.cdc.gov/view/cdc/258726 Journal Title : Journal of Occupational and Environmental Medicine
Santos, Chavez et al. (2026). A Cross-Sectional Legal Epidemiology Study of Associations Between State-Level Labor Laws (LLEI) and Workplace Sanitation and Training Indicators Among Hispanic US Crop Workers Using the National Agricultural Workers Survey (NAWS). Journal of Occupational and Environmental Medicine. 68(4).

Santos, Chavez et al. "A Cross-Sectional Legal Epidemiology Study of Associations Between State-Level Labor Laws (LLEI) and Workplace Sanitation and Training Indicators Among Hispanic US Crop Workers Using the National Agricultural Workers Survey (NAWS)" Journal of Occupational and Environmental Medicine 68, no. 4 (2026)

Santos, Chavez et al. "A Cross-Sectional Legal Epidemiology Study of Associations Between State-Level Labor Laws (LLEI) and Workplace Sanitation and Training Indicators Among Hispanic US Crop Workers Using the National Agricultural Workers Survey (NAWS)" Journal of Occupational and Environmental Medicine, vol. 68, no. 4, 2026
Export RIS Citation Information. TY - Journal Article AU - Santos, Chavez AU - Orenlas, India AU - Hill, Heather AU - Spector, June T. AU - Flunker, John C. AU - Baquero, Barbara AB - Objective: Agricultural workers are at a disproportionate risk of work-related injuries and illnesses. We examined how labor laws are associated with agricultural workers' work environments. Methods: We conducted a cross-sectional study of Hispanic/Latine participants in the National Agricultural Workers Survey to assess the association between a Labor Law Equity Index (LLEI), which summarizes agricultural worker inclusion or exclusion in workers' compensation, minimum wage, and overtime pay laws across US states, and workplace conditions. Results: Higher LLEI scores were associated with an increased odds of employer provision of water (adjusted odds ratio [aOR] = 1.18, 95% confidence interval [CI]: 1.05 to 1.33), toilet (aOR = 1.50, 95% CI: 1.34 to 1.67), hand-washing station (aOR = 1.40, 95% CI: 1.26 to 1.56), and pesticide training (aOR = 1.19, 95% CI: 1.10 to 1.29). Conclusion: Our results highlight policy-related opportunities to improve workplace water access, sanitation, and training implementation to better support agricultural worker health. AN - cdc:258726 IS - 4 J2 - Journal of Occupational and Environmental Medicine KW - Epidemiology KW - Agriculture KW - Safety KW - Occupational Health KW - Agricultural workers; Work environment; Cross sectional studies; Epidemiology; Regulations; Hand washing; Drinking water; Training; Policy; Worker health; KW - Author Keywords: labor laws; occupational health and safety; agricultural worker health KW - Agriculture KW - Epidemiology KW - Occupational Health KW - Safety PY - 2026/04/01 T2 - Journal of Occupational and Environmental Medicine T2 - J Occup Environ Med 2026 Apr; 68(4):e288-e294 TI - A Cross-Sectional Legal Epidemiology Study of Associations Between State-Level Labor Laws (LLEI) and Workplace Sanitation and Training Indicators Among Hispanic US Crop Workers Using the National Agricultural Workers Survey (NAWS) VL - 68 UR - https://stacks.cdc.gov/view/cdc/258726 ER -
Health Hazard Evaluation Report No. 2024-0053-3431: Evaluation of Exposure to Polychlorinated Biphenyls (PCBs) and Cancer Concerns Among University Employees

Rinsky, Jessica L. ;

Chiu, Sophia K.

2026/03/01 | Health Hazard Evaluation Reports (HHE)

Management from a university requested a health hazard evaluation concerning potential workplace exposure to polychlorinated biphenyls (PCBs) and the occurrence of cancer among employees working in a university building. During our evaluation we (1) reviewed available scientific literature about cancer types associated with PCB exposure, (2) review ...

08/10/2026

Title : Health Hazard Evaluation Report No. 2024-0053-3431: Evaluation of Exposure to Polychlorinated Biphenyls (PCBs) and Cancer Concerns Among University Employees Personal Author(s) : Rinsky, Jessica L.;Chiu, Sophia K.;Burton, Nancy C.;Neu, Dylan T.;Feldmann, Karl D.; Published Date : 2026/03/01 Pages in Document : 48 pdf pages Series : Health Hazard Evaluation Reports (HHE) Source : Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, HHE 2024-0053-3431, 2026 Mar; :1-47 DOI : 10.26616/NIOSHHHE202400533431 Journal Title : National Institute for Occupational Safety and Health
Rinsky, Jessica L. et al. (2026). Health Hazard Evaluation Report No. 2024-0053-3431: Evaluation of Exposure to Polychlorinated Biphenyls (PCBs) and Cancer Concerns Among University Employees. National Institute for Occupational Safety and Health. https://doi.org/10.26616/NIOSHHHE202400533431

Rinsky, Jessica L. et al. "Health Hazard Evaluation Report No. 2024-0053-3431: Evaluation of Exposure to Polychlorinated Biphenyls (PCBs) and Cancer Concerns Among University Employees" National Institute for Occupational Safety and Health (2026), https://doi.org/10.26616/NIOSHHHE202400533431

Rinsky, Jessica L. et al. "Health Hazard Evaluation Report No. 2024-0053-3431: Evaluation of Exposure to Polychlorinated Biphenyls (PCBs) and Cancer Concerns Among University Employees" National Institute for Occupational Safety and Health, , 2026, https://doi.org/10.26616/NIOSHHHE202400533431
Export RIS Citation Information. TY - Field Study AU - Rinsky, Jessica L. AU - Chiu, Sophia K. AU - Burton, Nancy C. AU - Neu, Dylan T. AU - Feldmann, Karl D. AB - Management from a university requested a health hazard evaluation concerning potential workplace exposure to polychlorinated biphenyls (PCBs) and the occurrence of cancer among employees working in a university building. During our evaluation we (1) reviewed available scientific literature about cancer types associated with PCB exposure, (2) reviewed reports describing environmental assessments and air, surface, and bulk building material sampling conducted by the university and a consultant, (3) worked with the state cancer registry to estimate the number of cases of melanoma, breast cancer, and non-Hodgkin lymphoma that occurred among university employees who worked in the building during 1995-2022, and (4) compared the occurrence of each cancer type among employees to the number of cases expected if employees experienced the same cancer rates as the general population of the state. Environmental assessments and sampling showed that PCBs were detected in air and on surfaces in workspaces, indicating it is possible employees could have been exposed. However, the available information did not show when the potential for PCB exposure began, how levels have changed over time, or if employees were exposed at levels known or suspected of causing cancer. Our evaluation suggests that the incidence of melanoma, and possibly breast cancer, was greater than expected based on statewide rates during the period evaluated, mainly among female employees assigned to the building. However, NIOSH cannot draw conclusions about the causes of these cancers among employees based on this information alone. The excesses of cancer observed here may be due to many different factors, including differences in access to cancer screening and medical care between employees and the general population. These results begin to address employee and university concerns about the potential for exposure to PCBs in the building and the occurrence of cancer among employees, indicate steps that affected individuals can take, and support the need to consider whether further investigation of the potential for PCB exposure over time and health effects among building occupants is possible and would substantially benefit the university community. AN - cdc:258725 DO - 10.26616/NIOSHHHE202400533431 J2 - National Institute for Occupational Safety and Health KW - Schools KW - Polychlorinated Biphenyls KW - Neoplasms KW - Safety KW - Occupational Health KW - Breast Neoplasms KW - Region 4; Education; Employee health; Cancer; Breast cancer; Polychlorinated biphenyls; PCBs; Indoor environments; Construction materials; KW - Author Keywords: Colleges, Universities, and Professional Schools; Cancer; Polychlorinated Biphenyls; PCBs KW - Breast Neoplasms KW - Neoplasms KW - Occupational Health KW - Polychlorinated Biphenyls KW - Safety KW - Schools PB - National Institute for Occupational Safety and Health PY - 2026/03/01 T2 - National Institute for Occupational Safety and Health T2 - Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, HHE 2024-0053-3431, 2026 Mar; :1-47 T3 - Health Hazard Evaluation Reports (HHE) TI - Health Hazard Evaluation Report No. 2024-0053-3431: Evaluation of Exposure to Polychlorinated Biphenyls (PCBs) and Cancer Concerns Among University Employees UR - https://stacks.cdc.gov/view/cdc/258725 ER -
Attitudes of Fire Service Personnel Toward Respiratory Protection in Wildland Firefighting

Dawit, Eden ;

Naeem, Shafaq

2026/03/01 | Ann Work Expo Health 2026 Mar; 70(2):1-12 | National Institute for Occupational Safety and Health (NIOSH)

Wildland and wildland-urban interface (W/WUI) fires are increasing in frequency and intensity, increasing concerns about firefighters' exposure to hazardous smoke and the need for respiratory protection. This qualitative study explored the perspectives of California fire service personnel on the use of respiratory protective devices (RPDs), particu ...

08/10/2026

Title : Attitudes of Fire Service Personnel Toward Respiratory Protection in Wildland Firefighting Personal Author(s) : Dawit, Eden;Naeem, Shafaq;Vinegar, Sophia;Styles, Laura;Jones, Rachel M.; Published Date : 2026/03/01 Pages in Document : 12 pdf pages Source : Ann Work Expo Health 2026 Mar; 70(2):1-12 URL : https://stacks.cdc.gov/view/cdc/258724 Journal Title : Annals of Work Exposures and Health
Dawit, Eden et al. (2026). Attitudes of Fire Service Personnel Toward Respiratory Protection in Wildland Firefighting. Annals of Work Exposures and Health. 70

Dawit, Eden et al. "Attitudes of Fire Service Personnel Toward Respiratory Protection in Wildland Firefighting" Annals of Work Exposures and Health 70 (2026)

Dawit, Eden et al. "Attitudes of Fire Service Personnel Toward Respiratory Protection in Wildland Firefighting" Annals of Work Exposures and Health, vol. 70, 2026
Export RIS Citation Information. TY - Journal Article AU - Dawit, Eden AU - Naeem, Shafaq AU - Vinegar, Sophia AU - Styles, Laura AU - Jones, Rachel M. AB - Wildland and wildland-urban interface (W/WUI) fires are increasing in frequency and intensity, increasing concerns about firefighters' exposure to hazardous smoke and the need for respiratory protection. This qualitative study explored the perspectives of California fire service personnel on the use of respiratory protective devices (RPDs), particularly powered air-purifying respirators, and a potential Cal/OSHA regulation mandating their use in W/WUI firefighting. Participants were experienced in W/WUI firefighting and had some role in their fire department related to respiratory protection or other aspect of firefighter safety. While all participants recognized the health risks associated with smoke exposure, including cancer and acute respiratory symptoms, and that RPDs would reduce their exposures, participants had concerns that RPDs would negatively affect fatigue, comfort, communication, mobility, and situational awareness. Some concerns specifically relate to the design of the RPDs. Most participants supported using RPDs in specific scenarios such as mop-up and prescribed burns, but fewer supported RPD use during high-exertion tasks like cutting line. Participants preferred flexibility or guidance rather than prescriptive regulation and advocated for engagement of firefighters in the development of any potential regulation to ensure practicality and feasibility. Some participants acknowledged resistance to change in the industry as a barrier for RPD adoption, but felt that evidence of RPD effectiveness and usability, including opportunities for training with devices and changes to device design, could assist with adoption. A programmatic regulation, coupled with education and engagement, can facilitate the incorporation of RPDs in W/WUI firefighting. AN - cdc:258724 J2 - Annals of Work Exposures and Health KW - Fires KW - Respiratory System KW - Respiratory Protective Devices KW - Firefighters KW - Safety KW - Occupational Health KW - Fire fighters; Wildland fires; Wildland fire smoke; Respiratory protection; Qualitative analysis; Respiratory protective equipment; Powered air purifying respirator; PAPR; Regulations; KW - Author Keywords: fire departments; occupational health; powered air-purifying respirator; qualitative research; regulation KW - Fires KW - Firefighters KW - Occupational Health KW - Respiratory System KW - Respiratory Protective Devices KW - Safety PY - 2026/03/01 T2 - Annals of Work Exposures and Health T2 - Ann Work Expo Health 2026 Mar; 70(2):1-12 TI - Attitudes of Fire Service Personnel Toward Respiratory Protection in Wildland Firefighting VL - 70 UR - https://stacks.cdc.gov/view/cdc/258724 ER -
Does Work-Family Conflict Predict Allostatic Load? A 4-Year Longitudinal Study

Saiki, Mayumi ;

Loerbroks, Adrian

2025/12/01 | Postgrad Med J 2025 Dec; 101(1202):1303-1310 | National Institute for Occupational Safety and Health (NIOSH)

Objective: A growing number of studies have reported that occupational psychosocial factors increase the risk of cardiovascular disease. Allostatic load (AL) is a main biological mechanism that explains the pathway from stress to disease. This study examined whether work-to-family conflict (WFC) and family-to-work conflict (FWC) at baseline would b ...

08/10/2026

Title : Does Work-Family Conflict Predict Allostatic Load? A 4-Year Longitudinal Study Personal Author(s) : Saiki, Mayumi;Loerbroks, Adrian;Li, Jian; Published Date : 2025/12/01 Pages in Document : 8 pdf pages Source : Postgrad Med J 2025 Dec; 101(1202):1303-1310 URL : https://stacks.cdc.gov/view/cdc/258723 Journal Title : Postgraduate Medical Journal
Saiki, Mayumi et al. (2025). Does Work-Family Conflict Predict Allostatic Load? A 4-Year Longitudinal Study. Postgraduate Medical Journal. 101(1202).

Saiki, Mayumi and Loerbroks, Adrian and Li, Jian "Does Work-Family Conflict Predict Allostatic Load? A 4-Year Longitudinal Study" Postgraduate Medical Journal 101, no. 1202 (2025)

Saiki, Mayumi et al. "Does Work-Family Conflict Predict Allostatic Load? A 4-Year Longitudinal Study" Postgraduate Medical Journal, vol. 101, no. 1202, 2025
Export RIS Citation Information. TY - Journal Article AU - Saiki, Mayumi AU - Loerbroks, Adrian AU - Li, Jian AB - Objective: A growing number of studies have reported that occupational psychosocial factors increase the risk of cardiovascular disease. Allostatic load (AL) is a main biological mechanism that explains the pathway from stress to disease. This study examined whether work-to-family conflict (WFC) and family-to-work conflict (FWC) at baseline would be associated with changes in the AL index (ALI) across four years. Methods: We used the Midlife in Japan survey, Wave I, and the biomarker projects, Waves I and II. This study included 152 participants with paid jobs and variables of interest at baseline and target biomarkers at baseline and follow-up. We examined the four-year longitudinal changes in the ALI using two methods: comparing ALI scores at baseline and follow-up, named "Two ALI approach," and creating one ALI score considering changes at baseline and follow-up, named "One ALI approach." Negative binomial regression analysis and generalized estimating equations were used for analyses. The results were reported by count ratios (CRs) and 95% confidence intervals (CIs). Results: In the final model, our results demonstrated that WFC at baseline was significantly associated with increased ALI using the "Two ALI approach" (CR 1.15, 95% CIs: 1.03, 1.28) and "One ALI approach" (CR 1.15, 95% CIs: 1.01, 1.32), whereas FWC did not show statistical significance in both methods. Conclusions: WFC was longitudinally associated with increased ALI. It is crucial to mitigate the effects of work-to-family conflict. AN - cdc:258723 IS - 1202 J2 - Postgraduate Medical Journal KW - Safety KW - Cardiovascular System KW - Stress, Psychological KW - Occupational Health KW - Longitudinal study; Work-family conflict; Cardiovascular disease; Stress; Biological effects; KW - Author Keywords: work-family conflict; allostatic load index; biological stress responses; longitudinal study KW - Cardiovascular System KW - Occupational Health KW - Safety KW - Stress, Psychological PY - 2025/12/01 T2 - Postgraduate Medical Journal T2 - Postgrad Med J 2025 Dec; 101(1202):1303-1310 TI - Does Work-Family Conflict Predict Allostatic Load? A 4-Year Longitudinal Study VL - 101 UR - https://stacks.cdc.gov/view/cdc/258723 ER -
Hypohydration Augments the Acute Increase in Urinary Biomarkers of Kidney Injury Following the 100-Mile Western States Endurance Run

Linder, Braxton A.

;

Jeong, Soolim

2025/11/01 | J Appl Physiol 2025 Nov; 139(5):1379-1391 | National Institute for Occupational Safety and Health (NIOSH)

Ultraendurance races may transiently increase acute kidney injury (AKI) risk, yet data on contributing factors are sparse. Therefore, we examined the acute effects of the Western States Endurance Run [WSER (100 miles; 161 km)] on urinary AKI biomarkers and kidney blood flow, while also assessing the influence of race pace and hydration status. Bloo ...

08/10/2026

Title : Hypohydration Augments the Acute Increase in Urinary Biomarkers of Kidney Injury Following the 100-Mile Western States Endurance Run Personal Author(s) : Linder, Braxton A.;Jeong, Soolim;Stute, Nina L.;El-Kurd, Omar B.;Vondrasek, Joseph D.;Pasternak, Andrew;Bagley, James R.;Watso, Joseph C.;Schlader, Zachary J.;Babcock, Matthew C.;Grosicki, Gregory J.;Robinson, Austin T.; Published Date : 2025/11/01 Pages in Document : 13 pdf pages Source : J Appl Physiol 2025 Nov; 139(5):1379-1391 URL : https://stacks.cdc.gov/view/cdc/258722 Journal Title : Journal of Applied Physiology
Linder, Braxton A. et al. (2025). Hypohydration Augments the Acute Increase in Urinary Biomarkers of Kidney Injury Following the 100-Mile Western States Endurance Run. Journal of Applied Physiology. 139

Linder, Braxton A. et al. "Hypohydration Augments the Acute Increase in Urinary Biomarkers of Kidney Injury Following the 100-Mile Western States Endurance Run" Journal of Applied Physiology 139 (2025)

Linder, Braxton A. et al. "Hypohydration Augments the Acute Increase in Urinary Biomarkers of Kidney Injury Following the 100-Mile Western States Endurance Run" Journal of Applied Physiology, vol. 139, 2025
Export RIS Citation Information. TY - Journal Article AU - Linder, Braxton A. AU - Jeong, Soolim AU - Stute, Nina L. AU - El-Kurd, Omar B. AU - Vondrasek, Joseph D. AU - Pasternak, Andrew AU - Bagley, James R. AU - Watso, Joseph C. AU - Schlader, Zachary J. AU - Babcock, Matthew C. AU - Grosicki, Gregory J. AU - Robinson, Austin T. AB - Ultraendurance races may transiently increase acute kidney injury (AKI) risk, yet data on contributing factors are sparse. Therefore, we examined the acute effects of the Western States Endurance Run [WSER (100 miles; 161 km)] on urinary AKI biomarkers and kidney blood flow, while also assessing the influence of race pace and hydration status. Blood and urine samples were collected to assess urine specific gravity (USG), creatinine, and AKI risk [nephrin, neutrophil gelatinase-associated lipocalin (NGAL), insulin-like growth factor binding protein 7 (IGFBP7), tissue inhibitor of metalloproteinase 2 (TIMP2), and IGFBP-7·TIMP-2]. Renal blood velocity and conductance were measured via Doppler ultrasonography. Pre and post measures were obtained from 36 runners (29 males/7 females, age: 44 +/- 9 yr, mean finish time: 25:45:55). Urinary AKI biomarkers increased postrace, with nephrin, IGFBP7, and IGFBP7·TIMP-2 remaining elevated after indexing to creatinine (Ps < 0.008). Hydration status declined, with only 8 of 35 runners remaining euhydrated postrace. Finishing euhydrated attenuated increases in urinary creatinine and creatinine-indexed IGFBP-7·TIMP-2 (Ps ≤ 0.006). Faster race pace correlated with increases in USG (rho = 0.338, P = 0.048) and urinary creatinine (rho = 0.443, P = 0.010), but not with creatinine-indexed AKI biomarkers (Ps ≥ 0.382). Kidney blood velocity and conductance were unchanged (Ps ≥ 0.186). Finishing hydrated appears to help mitigate the transient increase in kidney injury following an ultraendurance race. NEW & NOTEWORTHY Urinary concentrations of several acute kidney injury (AKI) biomarkers increased after completing the 2023 Western States Endurance Run; however, there were no changes in renal blood flow in a subset of runners. When normalized to creatinine, several AKI biomarkers, including IGFBP7·TIMP2 (an FDA-approved biomarker of AKI), remained elevated. Notably, finishing the race euhydrated appeared to have a protective effect, mitigating increases in IGFBP7·TIMP2. AN - cdc:258722 J2 - Journal of Applied Physiology KW - Biomarkers KW - Dehydration KW - Exercise KW - Safety KW - Kidney KW - Occupational Health KW - Kidney function; Physiology; Dehydration; Biomarkers; Kinesiology; Physical exercise; KW - Author Keywords: acute kidney injury; hydration; performance; renal blood flow; ultramarathon KW - Biomarkers KW - Dehydration KW - Exercise KW - Kidney KW - Occupational Health KW - Safety PY - 2025/11/01 T2 - Journal of Applied Physiology T2 - J Appl Physiol 2025 Nov; 139(5):1379-1391 TI - Hypohydration Augments the Acute Increase in Urinary Biomarkers of Kidney Injury Following the 100-Mile Western States Endurance Run VL - 139 UR - https://stacks.cdc.gov/view/cdc/258722 ER -
The Potential Efficacy of Continuous Plantar Foot Cooling During Relatively Mild Simulated Occupational Heat Stress - A Pilot Study

Keeler, Jason M. ;

Walker, Charlie

2025/11/18 | Eur J Appl Physiol 2025 Nov; :Epub ahead of print | National Institute for Occupational Safety and Health (NIOSH)

Purpose: To identify the effect size regarding glabrous skin foot cooling on core temperature, cognitive performance, and physical work capacity (PWC) during mild simulated occupational heat stress. Methods: A pilot sample of twelve healthy adults (5 women) completed experimental visits in a 38.7 +/- 0.7 degrees C, and 46 +/- 9% relative humidity e ...

08/10/2026

Title : The Potential Efficacy of Continuous Plantar Foot Cooling During Relatively Mild Simulated Occupational Heat Stress - A Pilot Study Personal Author(s) : Keeler, Jason M.;Walker, Charlie;Regester, Amanda;Heikkinen, Molly E.;Johnson, Blair D.;Ju, Y. Sungtaek;Jin, Lihua;Schlader, Zachary J.; Published Date : 2025/11/18 Pages in Document : 15 pdf pages Source : Eur J Appl Physiol 2025 Nov; :[Epub ahead of print] URL : https://stacks.cdc.gov/view/cdc/258721 Journal Title : European Journal of Applied Physiology
Keeler, Jason M. et al. (2025). The Potential Efficacy of Continuous Plantar Foot Cooling During Relatively Mild Simulated Occupational Heat Stress - A Pilot Study. European Journal of Applied Physiology.

Keeler, Jason M. et al. "The Potential Efficacy of Continuous Plantar Foot Cooling During Relatively Mild Simulated Occupational Heat Stress - A Pilot Study" European Journal of Applied Physiology (2025)

Keeler, Jason M. et al. "The Potential Efficacy of Continuous Plantar Foot Cooling During Relatively Mild Simulated Occupational Heat Stress - A Pilot Study" European Journal of Applied Physiology, , 2025
Export RIS Citation Information. TY - Journal Article AU - Keeler, Jason M. AU - Walker, Charlie AU - Regester, Amanda AU - Heikkinen, Molly E. AU - Johnson, Blair D. AU - Ju, Y. Sungtaek AU - Jin, Lihua AU - Schlader, Zachary J. AB - Purpose: To identify the effect size regarding glabrous skin foot cooling on core temperature, cognitive performance, and physical work capacity (PWC) during mild simulated occupational heat stress. Methods: A pilot sample of twelve healthy adults (5 women) completed experimental visits in a 38.7 +/- 0.7 degrees C, and 46 +/- 9% relative humidity environment that consisted of 60-minutes of steady-state upper body ergometry exercise followed by a 60-minute PWC test involving upper body ergometry while maintaining a rating of perceived exertion of 13 ("somewhat hard"). In one trial, participants stood with bare feet on cooled plates (17.7 +/- 0.5 degrees C,) and in the other they were on noncooled plates (36.5 +/- 0.1 degrees C,), with the order assigned in a block randomized manner. Results: Core temperature increased during steady-state exercise (from 37.5 +/- 0.3 to 37.6 +/- 0.3 degrees C,, p < 0.003) and the PWC test (from 37.6 +/- 0.3 to 37.9 +/- 0.3 degrees C, p < 0.001), but there was no difference between conditions (mean difference 0.03+/-0.18 degrees C,, p = 0.592, dz=0.112). During the PWC test, there was no difference between conditions for mean power output (p = 0.213, dz=0.184), with the final power outputs of 28 +/- 9 W and 30 +/- 9 W for control and cooling conditions, respectively. There were no condition effects for cognitive performance on any measure (p = 0.207, dz=0.405). However, foot cooling (+ 15 +/- 9 bpm) reduced increases of heart rate during the PWC test compared to control (+ 21 +/- 11 bpm, p = 0.013, dz=0.425). Conclusion: Glabrous skin foot cooling has a relatively small effect on core temperature and PWC, but moderate effects on cognitive performance and heart rate during short duration (approx. 3 h) mild heat stress. AN - cdc:258721 J2 - European Journal of Applied Physiology KW - Safety KW - Heat Stress Disorders KW - Occupational Health KW - Heat stress; Cognitive function; Body temperature; Work capacity; Humidity; Heart rate; KW - Author Keywords: Heat stress; Foot cooling; Core temperature; Work capacity KW - Heat Stress Disorders KW - Occupational Health KW - Safety PY - 2025/11/18 T2 - European Journal of Applied Physiology T2 - Eur J Appl Physiol 2025 Nov; :[Epub ahead of print] TI - The Potential Efficacy of Continuous Plantar Foot Cooling During Relatively Mild Simulated Occupational Heat Stress - A Pilot Study UR - https://stacks.cdc.gov/view/cdc/258721 ER -
Inducible Laryngeal Obstruction in a Healthcare Worker Exposed to Hydrogen Peroxide, Peracetic Acid, and Acetic Acid

Foreman, Anne M. ;

Blackley, Brie H.

2025/10/28 | Respir Med Case Rep 2025 Oct; 58:102306 | National Institute for Occupational Safety and Health (NIOSH)

This report describes a case of severe inducible laryngeal obstruction (ILO) in an emergency department nurse. Onset of the condition occurred after an episode of exposure to a disinfectant product containing hydrogen peroxide, peracetic acid, and acetic acid. Previously exposures had been tolerated by the nurse over a period of nine months. Influe ...

08/10/2026

Title : Inducible Laryngeal Obstruction in a Healthcare Worker Exposed to Hydrogen Peroxide, Peracetic Acid, and Acetic Acid Personal Author(s) : Foreman, Anne M.;Blackley, Brie H.;Harvey, R. Reid;Hines, Stella E.; Published Date : 2025/10/28 Pages in Document : 5 pdf pages Source : Respir Med Case Rep 2025 Oct; 58:102306 URL : https://stacks.cdc.gov/view/cdc/258720 Journal Title : Respiratory Medicine Case Reports
Foreman, Anne M. et al. (2025). Inducible Laryngeal Obstruction in a Healthcare Worker Exposed to Hydrogen Peroxide, Peracetic Acid, and Acetic Acid. Respiratory Medicine Case Reports. 58

Foreman, Anne M. et al. "Inducible Laryngeal Obstruction in a Healthcare Worker Exposed to Hydrogen Peroxide, Peracetic Acid, and Acetic Acid" Respiratory Medicine Case Reports 58 (2025)

Foreman, Anne M. et al. "Inducible Laryngeal Obstruction in a Healthcare Worker Exposed to Hydrogen Peroxide, Peracetic Acid, and Acetic Acid" Respiratory Medicine Case Reports, vol. 58, 2025
Export RIS Citation Information. TY - Journal Article AU - Foreman, Anne M. AU - Blackley, Brie H. AU - Harvey, R. Reid AU - Hines, Stella E. AB - This report describes a case of severe inducible laryngeal obstruction (ILO) in an emergency department nurse. Onset of the condition occurred after an episode of exposure to a disinfectant product containing hydrogen peroxide, peracetic acid, and acetic acid. Previously exposures had been tolerated by the nurse over a period of nine months. Influenza infection may have been a predisposing factor. Despite various interventions, including botulinum toxin A injections, suture lateralization of the right true vocal cord, and right CO2 laser transverse cordotomy with partial medial arytenoidectomy, the patient continued to experience severe symptoms. Ultimately, a tracheostomy was performed to alleviate the obstruction. This case highlights the need for heightened clinician awareness, early and accurate diagnosis, and the development of effective management strategies for ILO patients. AN - cdc:258720 J2 - Respiratory Medicine Case Reports KW - Respiratory System KW - Hydrogen Peroxide KW - Safety KW - Health Personnel KW - Peracetic Acid KW - Acetic Acid KW - Occupational Health KW - Nurses KW - Disinfectants; Hydrogen peroxide; Peracetic acid; Acetic acid; Airway obstruction; Health care workers; Cleaning compounds; Nurses KW - Acetic Acid KW - Health Personnel KW - Hydrogen Peroxide KW - Nurses KW - Occupational Health KW - Peracetic Acid KW - Respiratory System KW - Safety PY - 2025/10/28 T2 - Respiratory Medicine Case Reports T2 - Respir Med Case Rep 2025 Oct; 58:102306 TI - Inducible Laryngeal Obstruction in a Healthcare Worker Exposed to Hydrogen Peroxide, Peracetic Acid, and Acetic Acid VL - 58 UR - https://stacks.cdc.gov/view/cdc/258720 ER -
Efforts to Enhance Participation in the National Institute for Occupational Safety and Health B Reader Program

Laney, A. Scott

;

Hall, Noemi B.

2025/12/01 | Chest 2025 Dec; 168(6):1443-1445 | National Institute for Occupational Safety and Health (NIOSH)

For over 50 years, the National Institute for Occupational Safety and Health (NIOSH) has administered the NIOSH B Reader Program. NIOSH B Reader certification is granted after successful completion of an examination testing competency in classifying posteroanterior chest radiographs for appearances of pneumoconiosis, using the International Labour ...

08/10/2026

Title : Efforts to Enhance Participation in the National Institute for Occupational Safety and Health B Reader Program Personal Author(s) : Laney, A. Scott;Hall, Noemi B.;Reynolds, Laura E.;Weissman, David N.; Published Date : 2025/12/01 Pages in Document : 3 pdf pages Source : Chest 2025 Dec; 168(6):1443-1445 URL : https://stacks.cdc.gov/view/cdc/258719 Journal Title : Chest
Laney, A. Scott et al. (2025). Efforts to Enhance Participation in the National Institute for Occupational Safety and Health B Reader Program. Chest. 168(6).

Laney, A. Scott et al. "Efforts to Enhance Participation in the National Institute for Occupational Safety and Health B Reader Program" Chest 168, no. 6 (2025)

Laney, A. Scott et al. "Efforts to Enhance Participation in the National Institute for Occupational Safety and Health B Reader Program" Chest, vol. 168, no. 6, 2025
Export RIS Citation Information. TY - Report AU - Laney, A. Scott AU - Hall, Noemi B. AU - Reynolds, Laura E. AU - Weissman, David N. AB - For over 50 years, the National Institute for Occupational Safety and Health (NIOSH) has administered the NIOSH B Reader Program. NIOSH B Reader certification is granted after successful completion of an examination testing competency in classifying posteroanterior chest radiographs for appearances of pneumoconiosis, using the International Labour Office's (ILO) International Classification of Radiographs of Pneumoconioses. This examination is currently open only to licensed physicians, including but not limited to radiologists and pulmonologists. The ILO classification system established a standard vocabulary for describing radiographic shadows on chest films for epidemiologic studies and the ability to compare such studies across research groups and over time. The system has been adopted for medicolegal purposes and determination of eligibility for benefits in some settings. Although more advanced imaging technologies such as chest CT scans have largely displaced posteroanterior chest radiography for diagnostic purposes in the clinical setting, state and federal regulations rely on ILO classification, often called "B reading" of posteroanterior chest radiographic images for worker surveillance and disability compensation purposes. As such, demand for B readers remains relatively high; however, the number of US-based certified B readers declined from the 1990s to approximately 2019 and has been stable since then (Fig 1). The cause of this decline is likely multifactorial and discussed by Halldin et al, and includes shifts in technology, training, and perceptions of demand. At its peak in 1993, there were 772 B readers, which dropped to 189 B readers in 2025. As of 2024, 212 B readers came from the following specialties: 151 in radiology, 26 in pulmonology, 16 in internal medicine, 5 in occupational medicine, and 14 other types of physicians. Although 71.2% of currently certified B readers are radiologists, this represents only 0.2% (151/66,000) of all board-certified radiologists in the United States. In 2016, the Occupational Safety and Health Administration and in 2024, the Mine Safety and Health Administration published final rules related to exposure to respirable crystalline silica, which include provisions related to worker monitoring involving chest radiograph interpretations by B readers. During the public comment period for these rules, some commentors raised concerns as to whether there were enough B readers to take on the potential increase in the number of radiographs that would require classification. One suggestion to meet the increasing demand for B readers was to allow nurse practitioners and physician assistants to take the B reader examination and subsequently become certified B readers if they successfully passed. The American Association of Nurse Practitioners had previously posted public comments to NIOSH suggesting that nurse practitioners be allowed to become B readers. AN - cdc:258719 IS - 6 J2 - Chest KW - Radiology KW - Respiratory System KW - Safety KW - Occupational Health KW - B reader certification program; Chest X-rays; Pneumoconiosis; Radiology; Physicians KW - Occupational Health KW - Radiology KW - Respiratory System KW - Safety PY - 2025/12/01 T2 - Chest T2 - Chest 2025 Dec; 168(6):1443-1445 TI - Efforts to Enhance Participation in the National Institute for Occupational Safety and Health B Reader Program VL - 168 UR - https://stacks.cdc.gov/view/cdc/258719 ER -
Barriers and Facilitators to Adoption of Winch Safety Equipment in Two U.S. Commercial Fisheries

Victoroff, Tristan M. ;

Teske, Theodore D.

2026/04/01 | J Agromedicine 2026 Apr; 31(2):173-185 | National Institute for Occupational Safety and Health (NIOSH)

Purpose: This study explored commercial fishermen's perspectives and decision-making process related to investment in winch safety equipment for fishing vessels. Methods: The study employed semi-structured interviews during 2019-2021 with commercial fishing captains, owners, equipment manufacturers, and suppliers (n = 19) from two different commerc ...

08/10/2026

Title : Barriers and Facilitators to Adoption of Winch Safety Equipment in Two U.S. Commercial Fisheries Personal Author(s) : Victoroff, Tristan M.;Teske, Theodore D.; Published Date : 2026/04/01 Pages in Document : 14 pdf pages Source : J Agromedicine 2026 Apr; 31(2):173-185 URL : https://stacks.cdc.gov/view/cdc/258718 Journal Title : Journal of Agromedicine
Victoroff, Tristan M. and Teske, Theodore D. (2026). Barriers and Facilitators to Adoption of Winch Safety Equipment in Two U.S. Commercial Fisheries. Journal of Agromedicine. 31(2).

Victoroff, Tristan M. and Teske, Theodore D. "Barriers and Facilitators to Adoption of Winch Safety Equipment in Two U.S. Commercial Fisheries" Journal of Agromedicine 31, no. 2 (2026)

Victoroff, Tristan M. and Teske, Theodore D. "Barriers and Facilitators to Adoption of Winch Safety Equipment in Two U.S. Commercial Fisheries" Journal of Agromedicine, vol. 31, no. 2, 2026
Export RIS Citation Information. TY - Journal Article AU - Victoroff, Tristan M. AU - Teske, Theodore D. AB - Purpose: This study explored commercial fishermen's perspectives and decision-making process related to investment in winch safety equipment for fishing vessels. Methods: The study employed semi-structured interviews during 2019-2021 with commercial fishing captains, owners, equipment manufacturers, and suppliers (n = 19) from two different commercial fisheries: the Pacific Northwest purse seine fleet, and the Southern shrimp fleet. Interview recordings were transcribed and qualitatively analyzed to identify themes related to adoption of winch safety gear. Results: Overall, perception of risk from deck winches was high in both populations. Fishermen generally regarded safety engineering interventions for winches positively, in principle. However, cost, installation complexity, and competing safety priorities are often barriers to adopting such equipment. In discussing safety-related investments, fishermen commonly prioritized maintenance of the vessel and management of the crew over mechanical safety equipment for the deck winch, despite its potential for causing injury. We identified several potential facilitators of adoption of winch safety equipment, particularly for the Southern shrimp fleet. Conclusions: Fishermen tend to view deck winch safety as part of a larger, complex set of safety considerations encompassing the vessel and crew as a whole. This risk balancing sometimes does not favor investment in safety gear specifically for the deck winch, even if it is perceived as a primary hazard. Fundamental economic conditions in these two fisheries continue to pose a challenge to widespread adoption of winch safety equipment. Reducing cost barriers would potentially be the most effective way to increase adoption, but additional work is needed to improve risk communication, increase awareness of available winch safety equipment, and address installation complexity barriers. AN - cdc:258718 IS - 2 J2 - Journal of Agromedicine KW - Hunting KW - Safety KW - Occupational Health KW - Fishing industry; Decision making; Safety equipment; Safety engineering; Traumatic injuries; Costs; KW - Author Keywords: Fishing; occupational safety and health; traumatic injury; winch safety KW - Hunting KW - Occupational Health KW - Safety PY - 2026/04/01 T2 - Journal of Agromedicine T2 - J Agromedicine 2026 Apr; 31(2):173-185 TI - Barriers and Facilitators to Adoption of Winch Safety Equipment in Two U.S. Commercial Fisheries VL - 31 UR - https://stacks.cdc.gov/view/cdc/258718 ER -
Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the Hsa-miR-381-3p/PPP3CA and Hsa-miR-381-3p/KLF4 Pathways in Response to 4,4′-Methylene Diphenyl Diisocyanate-Glutathione

Lin, Chen-Chung

;

Law, Brandon F.

2025/11/01 | Toxicol Sci 2025 Nov; 208(1):122-135 | National Institute for Occupational Safety and Health (NIOSH)

Workplace exposure to 4,4'-methylene diphenyl diisocyanate (MDI), the most used monomeric diisocyanate, can lead to the development of occupational asthma (OA). However, the molecular mechanisms by which MDI induces OA remain poorly understood. Previous studies have shown that exposure to MDI or MDI-glutathione (GSH) conjugate reduces the levels of ...

08/10/2026

Title : Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the Hsa-miR-381-3p/PPP3CA and Hsa-miR-381-3p/KLF4 Pathways in Response to 4,4′-Methylene Diphenyl Diisocyanate-Glutathione Personal Author(s) : Lin, Chen-Chung;Law, Brandon F.;Hettick, Justin M.; Published Date : 2025/11/01 Pages in Document : 14 pdf pages Source : Toxicol Sci 2025 Nov; 208(1):122-135 URL : https://stacks.cdc.gov/view/cdc/258717 Journal Title : Toxicological Sciences
Lin, Chen-Chung et al. (2025). Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the Hsa-miR-381-3p/PPP3CA and Hsa-miR-381-3p/KLF4 Pathways in Response to 4,4′-Methylene Diphenyl Diisocyanate-Glutathione. Toxicological Sciences. 208(1).

Lin, Chen-Chung and Law, Brandon F. and Hettick, Justin M. "Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the Hsa-miR-381-3p/PPP3CA and Hsa-miR-381-3p/KLF4 Pathways in Response to 4,4′-Methylene Diphenyl Diisocyanate-Glutathione" Toxicological Sciences 208, no. 1 (2025)

Lin, Chen-Chung et al. "Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the Hsa-miR-381-3p/PPP3CA and Hsa-miR-381-3p/KLF4 Pathways in Response to 4,4′-Methylene Diphenyl Diisocyanate-Glutathione" Toxicological Sciences, vol. 208, no. 1, 2025
Export RIS Citation Information. TY - Journal Article AU - Lin, Chen-Chung AU - Law, Brandon F. AU - Hettick, Justin M. AB - Workplace exposure to 4,4'-methylene diphenyl diisocyanate (MDI), the most used monomeric diisocyanate, can lead to the development of occupational asthma (OA). However, the molecular mechanisms by which MDI induces OA remain poorly understood. Previous studies have shown that exposure to MDI or MDI-glutathione (GSH) conjugate reduces the levels of endogenous human (hsa)/murine (mmu)-microRNA (miR)-206/381-3p, triggering the activation of calcineurin/nuclear factor of activated T-cells/inducible nitric oxide synthase (NOS2) regulatory axis and Krüppel-like factor 4 (KLF4)/chemokine pathways in macrophages. Circular RNAs (circRNAs) play important roles on miR and miR-mediated functions in the cells. CircRNA hsa_circ_0008726 is induced by MDI-GSH to downregulate endogenous hsa-miR-206-3p in macrophages; however, the MDI-GSH mediated circRNA response to downregulate hsa-miR-381-3p is currently unknown. The expression of previously identified candidate circRNAs that bind hsa-miR-381-3p were analyzed in differentiated/enhanced THP-1 macrophages treated with MDI-GSH conjugates using RT-qPCR. MDI-GSH exposure induces endogenous hsa_circ_0099188 and its host gene thyrotropin-releasing hormone-degrading ectoenzyme (TRHDE); however, other candidate circRNAs were neither detected nor altered. RNA immunoprecipitation experiments confirmed the binding of hsa-miR-381-3p to hsa_circ_0099188. Further experiments demonstrate that modulating hsa_circ_0099188 expression through siRNAs or overexpression plasmids alter the levels of endogenous hsa-miR-381-3p, PPP3CA, and KLF4, as well as NOS2 and M2 macrophage-associated markers and chemokine transcripts. These findings suggest that MDI/MDI-GSH exposure leads to the downregulation of hsa-miR-381-3p by inducing the expression of hsa_circ_0099188/TRHDE, thereby enhancing the regulatory effects of hsa-miR-381-3p in macrophages. AN - cdc:258717 IS - 1 J2 - Toxicological Sciences KW - Gene Expression KW - Safety KW - Asthma, Occupational KW - Occupational Health KW - 4,4-Methylene diphenyl diisocyanate; Occupational asthma; Gene expression; Macrophages; Cell signaling; Diisocyanates; Occupational exposure; Molecular biology; KW - Author Keywords: 4,4'-methylene diphenyl diisocyanate; MDI; circular RNAs; circRNAs; hsa-miR-381-3p; occupational asthma; OA; Krüppel-like factor 4; KLF4; protein phosphatase 3 catalytic subunit alpha; PPP3CA KW - Asthma, Occupational KW - Gene Expression KW - Occupational Health KW - Safety PY - 2025/11/01 T2 - Toxicological Sciences T2 - Toxicol Sci 2025 Nov; 208(1):122-135 TI - Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the Hsa-miR-381-3p/PPP3CA and Hsa-miR-381-3p/KLF4 Pathways in Response to 4,4′-Methylene Diphenyl Diisocyanate-Glutathione VL - 208 UR - https://stacks.cdc.gov/view/cdc/258717 ER -
Maternal Differences in Healthcare Provider-Led Conversations About Patients' Work Prior to Pregnancy, Pregnancy Risk Assessment Monitoring System, 2016-2021

Siegel, Miriam R. ;

Van Buren, Kristen

2025/11/01 | J Occup Environ Med 2025 Nov; 67(11):925-934 | National Institute for Occupational Safety and Health (NIOSH)

Objective: The aim of the study was to describe characteristics of women with a recent live birth who are, and are not, asked about their work by healthcare providers before pregnancy. Methods: We analyzed 2016-2021 data from 48 jurisdictions participating in the Pregnancy Risk Assessment Monitoring System. Questionnaires asked mothers about provid ...

08/10/2026

Title : Maternal Differences in Healthcare Provider-Led Conversations About Patients' Work Prior to Pregnancy, Pregnancy Risk Assessment Monitoring System, 2016-2021 Personal Author(s) : Siegel, Miriam R.;Van Buren, Kristen;Omari, Amel;Rocheleau, Carissa M.;Somerville, Nicholas J.; Published Date : 2025/11/01 Pages in Document : 10 pdf pages Source : J Occup Environ Med 2025 Nov; 67(11):925-934 URL : https://stacks.cdc.gov/view/cdc/258716 Journal Title : Journal of Occupational and Environmental Medicine
Siegel, Miriam R. et al. (2025). Maternal Differences in Healthcare Provider-Led Conversations About Patients' Work Prior to Pregnancy, Pregnancy Risk Assessment Monitoring System, 2016-2021. Journal of Occupational and Environmental Medicine. 67(11).

Siegel, Miriam R. et al. "Maternal Differences in Healthcare Provider-Led Conversations About Patients' Work Prior to Pregnancy, Pregnancy Risk Assessment Monitoring System, 2016-2021" Journal of Occupational and Environmental Medicine 67, no. 11 (2025)

Siegel, Miriam R. et al. "Maternal Differences in Healthcare Provider-Led Conversations About Patients' Work Prior to Pregnancy, Pregnancy Risk Assessment Monitoring System, 2016-2021" Journal of Occupational and Environmental Medicine, vol. 67, no. 11, 2025
Export RIS Citation Information. TY - Journal Article AU - Siegel, Miriam R. AU - Van Buren, Kristen AU - Omari, Amel AU - Rocheleau, Carissa M. AU - Somerville, Nicholas J. AB - Objective: The aim of the study was to describe characteristics of women with a recent live birth who are, and are not, asked about their work by healthcare providers before pregnancy. Methods: We analyzed 2016-2021 data from 48 jurisdictions participating in the Pregnancy Risk Assessment Monitoring System. Questionnaires asked mothers about provider-led conversations about their work. We descriptively compared weighted percentages with 95% confidence intervals across demographic and occupational characteristics. Results: Of 157,724 participants, 36% reported not being asked about their work by a provider in the year before pregnancy. Higher proportions of younger and lower-income mothers, certain Asian and Native groups, and mothers in some occupations and industries posing a risk of occupational hazards reported no provider-led conversations about their work. Conclusions: Healthcare providers can more routinely ask patients about work to assess for possible occupational hazards to pregnancy. AN - cdc:258716 IS - 11 J2 - Journal of Occupational and Environmental Medicine KW - Pregnancy KW - Surveys and Questionnaires KW - Safety KW - Urogenital System KW - Occupational Health KW - Women; Work experience; Pregnancy; Questionnaires; Occupational hazards; Health care; Occupational medicine; Reproductive health; KW - Author Keywords: occupational medicine; reproductive health; pregnancy; healthcare quality KW - Occupational Health KW - Pregnancy KW - Safety KW - Surveys and Questionnaires KW - Urogenital System PY - 2025/11/01 T2 - Journal of Occupational and Environmental Medicine T2 - J Occup Environ Med 2025 Nov; 67(11):925-934 TI - Maternal Differences in Healthcare Provider-Led Conversations About Patients' Work Prior to Pregnancy, Pregnancy Risk Assessment Monitoring System, 2016-2021 VL - 67 UR - https://stacks.cdc.gov/view/cdc/258716 ER -
Evaluation of Combustion Products in Air from Electric and Internal Combustion Engine Vehicles During Full-Scale Fire Experiments

Kesler, Richard M.

;

Sauer, Nathaniel

2025/12/01 | Fire Saf J 2025 Dec; 158:104558 | National Institute for Occupational Safety and Health (NIOSH)

The combustion of vehicles generates fire effluent that may contain compounds that pose unique health hazards. This study evaluated the composition of products of combustion that may present chronic health concerns from electric vehicles (EVs) and internal combustion engine vehicles (ICEVs). Six EVs and three ICEVs were ignited with a 30 kW burner ...

08/10/2026

Title : Evaluation of Combustion Products in Air from Electric and Internal Combustion Engine Vehicles During Full-Scale Fire Experiments Personal Author(s) : Kesler, Richard M.;Sauer, Nathaniel;Barowy, Adam;Probert, Chandler;Neumann, Danielle L.;Mayer, Alexander C.;Niemeier-Walsh, Micah;Fent, Kenneth W.;Stapleton, Heather M.;Horn, Gavin P.; Published Date : 2025/12/01 Pages in Document : 14 pdf pages Source : Fire Saf J 2025 Dec; 158:104558 URL : https://stacks.cdc.gov/view/cdc/258715 Journal Title : Fire Safety Journal
Kesler, Richard M. et al. (2025). Evaluation of Combustion Products in Air from Electric and Internal Combustion Engine Vehicles During Full-Scale Fire Experiments. Fire Safety Journal. 158

Kesler, Richard M. et al. "Evaluation of Combustion Products in Air from Electric and Internal Combustion Engine Vehicles During Full-Scale Fire Experiments" Fire Safety Journal 158 (2025)

Kesler, Richard M. et al. "Evaluation of Combustion Products in Air from Electric and Internal Combustion Engine Vehicles During Full-Scale Fire Experiments" Fire Safety Journal, vol. 158, 2025
Export RIS Citation Information. TY - Journal Article AU - Kesler, Richard M. AU - Sauer, Nathaniel AU - Barowy, Adam AU - Probert, Chandler AU - Neumann, Danielle L. AU - Mayer, Alexander C. AU - Niemeier-Walsh, Micah AU - Fent, Kenneth W. AU - Stapleton, Heather M. AU - Horn, Gavin P. AB - The combustion of vehicles generates fire effluent that may contain compounds that pose unique health hazards. This study evaluated the composition of products of combustion that may present chronic health concerns from electric vehicles (EVs) and internal combustion engine vehicles (ICEVs). Six EVs and three ICEVs were ignited with a 30 kW burner and allowed to burn until all combustible components of the entire vehicle were consumed. Active and passive air samplers were deployed 3.0 m in front of and 4.5 m behind the vehicle's bumpers, and in the smoke plume 8.7 m above the vehicle. Combustion gases were sampled for volatile organic compounds (VOCs), polycyclic aromatic hydrocarbons (PAHs), heavy metals, acid gases, per- and polyfluoroalkyl substances (PFAS), and inhalable particulates. EVs and ICEVs burned for similar durations, though EVs took longer to initially catch fire with this particular ignition method. Acid gases, VOCs, PFAS, PAHs, and inhalable particulates in the smoke showed minor differences between the vehicle types, though fluoride particulate was notably greater in the EV fires. Greater amounts of heavy metals (specifically nickel, manganese, cobalt, and lithium) were detected in the EV fire effluent relative to the ICEVs. Both EV and ICEV fires produce combustion products that could present health hazards to responders or bystanders. AN - cdc:258715 J2 - Fire Safety Journal KW - Motor Vehicles KW - Fires KW - Firefighters KW - Safety KW - Metals KW - Occupational Health KW - Particulate Matter KW - Fire fighters; Motor vehicles; Batteries; Smoke inhalation; Combustion products; Metals; Dermal exposures; Particulates; Fluoride; KW - Author Keywords: Electric vehicles; Internal combustion engine; Combustion products; Metals; Fluoride KW - Fires KW - Firefighters KW - Metals KW - Motor Vehicles KW - Occupational Health KW - Particulate Matter KW - Safety PY - 2025/12/01 T2 - Fire Safety Journal T2 - Fire Saf J 2025 Dec; 158:104558 TI - Evaluation of Combustion Products in Air from Electric and Internal Combustion Engine Vehicles During Full-Scale Fire Experiments VL - 158 UR - https://stacks.cdc.gov/view/cdc/258715 ER -
Exploring the Impact of High Reliability Organization Implementation on Patient Handling Injury Rates: A Cross-Sectional Study

Morales, Michael Joshua G. ;

Hilton, Pauline

2025/11/19 | J Occup Med Toxicol 2025 Nov; 20:40 | National Institute for Occupational Safety and Health (NIOSH)

Background: Patient handling injuries (PHIs) are among the leading causes of workplace injuries among healthcare workers. High-reliability organization (HRO) programs aim to prevent detrimental errors and improve organizational safety. This study examined the relationship between HRO implementation and direct care staffs' PHI rates. Methods: This c ...

08/10/2026

Title : Exploring the Impact of High Reliability Organization Implementation on Patient Handling Injury Rates: A Cross-Sectional Study Personal Author(s) : Morales, Michael Joshua G.;Hilton, Pauline;Hong, Oi Saeng;Bialous, Stella;Martin, Marie;Foley, Mary;Lee, Soo-Jeong; Published Date : 2025/11/19 Pages in Document : 10 pdf pages Source : J Occup Med Toxicol 2025 Nov; 20:40 URL : https://stacks.cdc.gov/view/cdc/258714 Journal Title : Journal of Occupational Medicine and Toxicology
Morales, Michael Joshua G. et al. (2025). Exploring the Impact of High Reliability Organization Implementation on Patient Handling Injury Rates: A Cross-Sectional Study. Journal of Occupational Medicine and Toxicology. 20(40).

Morales, Michael Joshua G. et al. "Exploring the Impact of High Reliability Organization Implementation on Patient Handling Injury Rates: A Cross-Sectional Study" Journal of Occupational Medicine and Toxicology 20, no. 40 (2025)

Morales, Michael Joshua G. et al. "Exploring the Impact of High Reliability Organization Implementation on Patient Handling Injury Rates: A Cross-Sectional Study" Journal of Occupational Medicine and Toxicology, vol. 20, no. 40, 2025
Export RIS Citation Information. TY - Journal Article AU - Morales, Michael Joshua G. AU - Hilton, Pauline AU - Hong, Oi Saeng AU - Bialous, Stella AU - Martin, Marie AU - Foley, Mary AU - Lee, Soo-Jeong AB - Background: Patient handling injuries (PHIs) are among the leading causes of workplace injuries among healthcare workers. High-reliability organization (HRO) programs aim to prevent detrimental errors and improve organizational safety. This study examined the relationship between HRO implementation and direct care staffs' PHI rates. Methods: This cross-sectional study used data from 124 Veterans Health Administration (VHA) facilities. HRO implementation was measured by program duration and HRO climate. Negative binomial regression models were used to examine the relationship between HRO implementation and PHI rates, progressively adjusting for staff-to-patient ratio, facility type, size, and complexity. Results: A longer HRO program duration was associated with higher HRO climate (p = .01), but HRO implementation (duration and climate) was not associated with PHI rates. Higher staff-to-patient ratio was associated with lower PHI rates (p < .05). Ambulatory care service facilities had lower PHI rates than acute care facilities (β = -0.824, p = .03). The most clinically complex facilities (level 1a) had higher PHI rates than the level 3 least complex facilities (β = 0.806, p = .04). Conclusion: While this study did not observe a significant relationship between HRO implementation and PHI rate among direct care staff, the study findings highlight the importance of adequate staffing for injury prevention and the need to consider facility type and complexity in PHI prevention efforts. Future research is needed to explore the impact of HRO on worker safety, using more sophisticated measures to assess HRO programs and climate. AN - cdc:258714 IS - 40 J2 - Journal of Occupational Medicine and Toxicology KW - Safety KW - Occupational Injuries KW - Health Personnel KW - Occupational Health KW - Musculoskeletal System KW - Patient handling; Health care workers; Cross sectional studies; Occupational safety; Injuries; Injury prevention; Worker safety; Musculoskeletal disorders; MSD; Work organization; KW - Author Keywords: High reliability organization; Organizational culture; Patient handling injury; Health care staff; Safe patient handling and mobility; Musculoskeletal disorders KW - Health Personnel KW - Musculoskeletal System KW - Occupational Health KW - Occupational Injuries KW - Safety PY - 2025/11/19 T2 - Journal of Occupational Medicine and Toxicology T2 - J Occup Med Toxicol 2025 Nov; 20:40 TI - Exploring the Impact of High Reliability Organization Implementation on Patient Handling Injury Rates: A Cross-Sectional Study VL - 20 UR - https://stacks.cdc.gov/view/cdc/258714 ER -
Telehealth Use Among Registered Nurses: A National Sample Survey Analysis

Castner, Jessica

;

Joshi, Aditi U.

2025/09/01 | Nurs Outlook 2025 Sep-Oct; 73(5):102522 | National Institute for Occupational Safety and Health (NIOSH)

Background: Telenursing utilization fluctuated during the COVID-19 pandemic response and recovery. Purpose: To determine United States nationally representative estimates in telenursing and ascertain disparities by practice rurality, patient population, and nurse racial identity. Methods: Applied epidemiological analysis of the 2022 National Sample ...

08/10/2026

Title : Telehealth Use Among Registered Nurses: A National Sample Survey Analysis Personal Author(s) : Castner, Jessica;Joshi, Aditi U.;Shaw, Ryan J.;Amberson, Taryn;Hetland, Breanna;Moscou-Jackson, Gyasi; Published Date : 2025/09/01 Pages in Document : 9 pdf pages Source : Nurs Outlook 2025 Sep-Oct; 73(5):102522 URL : https://stacks.cdc.gov/view/cdc/258713 Journal Title : Nursing Outlook
Castner, Jessica et al. (2025). Telehealth Use Among Registered Nurses: A National Sample Survey Analysis. Nursing Outlook. 73

Castner, Jessica et al. "Telehealth Use Among Registered Nurses: A National Sample Survey Analysis" Nursing Outlook 73 (2025)

Castner, Jessica et al. "Telehealth Use Among Registered Nurses: A National Sample Survey Analysis" Nursing Outlook, vol. 73, 2025
Export RIS Citation Information. TY - Journal Article AU - Castner, Jessica AU - Joshi, Aditi U. AU - Shaw, Ryan J. AU - Amberson, Taryn AU - Hetland, Breanna AU - Moscou-Jackson, Gyasi AB - Background: Telenursing utilization fluctuated during the COVID-19 pandemic response and recovery. Purpose: To determine United States nationally representative estimates in telenursing and ascertain disparities by practice rurality, patient population, and nurse racial identity. Methods: Applied epidemiological analysis of the 2022 National Sample Survey of Registered Nurses (RNs) with weighting for national representativeness. Findings: Weighted estimates represented 2,789,399 RNs. Limited telenursing use (22%) for inpatient and outpatient care was reported; the forms most frequently used were live videoconferencing (67%), audio calls (66%), and text or live chat (31%). Disparities by practice rurality and patient population were observed, but none by nurse racial identity. Discussion: Limited adoption of telenursing practice for inpatient and outpatient care was reported, despite pandemic conditions. Proactive policy development is needed to advance equal access to health services through telenursing use in rural areas, older adult practices, and pediatric nursing. AN - cdc:258713 J2 - Nursing Outlook KW - Safety KW - Health Personnel KW - Occupational Health KW - Telemedicine KW - Nurses KW - Nurses; Nursing; Health care workers; Medical care; Health services; Policy; COVID-19; KW - Author Keywords: Telehealth; Telenursing; Health policy; National Sample Survey of Registered Nurses; mHealth KW - Health Personnel KW - Nurses KW - Occupational Health KW - Safety KW - Telemedicine PY - 2025/09/01 T2 - Nursing Outlook T2 - Nurs Outlook 2025 Sep-Oct; 73(5):102522 TI - Telehealth Use Among Registered Nurses: A National Sample Survey Analysis VL - 73 UR - https://stacks.cdc.gov/view/cdc/258713 ER -
A PheWAS Analysis of the Risks and Benefits of Growing Up on a Farm

Burke, Richard R. ;

Berg, Richard L.

2026/04/01 | J Agromedicine 2026 Apr; 31(2):254-262 | National Institute for Occupational Safety and Health (NIOSH)

Objective: Growing up on a farm presents a health paradox, with increased risks of injuries but some purported benefits. This study estimated differences in the burden of medical comorbidities between youth who live versus do not live on farms. No a priori hypotheses were tested. Methods: A phenome-wide association study (PheWAS) was used in a coho ...

08/10/2026

Title : A PheWAS Analysis of the Risks and Benefits of Growing Up on a Farm Personal Author(s) : Burke, Richard R.;Berg, Richard L.;Weichelt, Bryan P.;Gabor, Rachel M.;Rudolphi, Josie M.;Bendixsen, Casper G.;VanWormer, Jeffrey J.; Published Date : 2026/04/01 Pages in Document : 10 pdf pages Source : J Agromedicine 2026 Apr; 31(2):254-262 URL : https://stacks.cdc.gov/view/cdc/258712 Journal Title : Journal of Agromedicine
Burke, Richard R. et al. (2026). A PheWAS Analysis of the Risks and Benefits of Growing Up on a Farm. Journal of Agromedicine. 31(2).

Burke, Richard R. et al. "A PheWAS Analysis of the Risks and Benefits of Growing Up on a Farm" Journal of Agromedicine 31, no. 2 (2026)

Burke, Richard R. et al. "A PheWAS Analysis of the Risks and Benefits of Growing Up on a Farm" Journal of Agromedicine, vol. 31, no. 2, 2026
Export RIS Citation Information. TY - Journal Article AU - Burke, Richard R. AU - Berg, Richard L. AU - Weichelt, Bryan P. AU - Gabor, Rachel M. AU - Rudolphi, Josie M. AU - Bendixsen, Casper G. AU - VanWormer, Jeffrey J. AB - Objective: Growing up on a farm presents a health paradox, with increased risks of injuries but some purported benefits. This study estimated differences in the burden of medical comorbidities between youth who live versus do not live on farms. No a priori hypotheses were tested. Methods: A phenome-wide association study (PheWAS) was used in a cohort of youth in north-central Wisconsin. Those who lived on farms were matched (1:3) to a non-farm comparison group. Outcomes included a comprehensive set of diagnoses (Phecodes) that occurred between 2017 and 2021. PheWAS analyses included logistic regression models of Phecode associations with farm residency. Results: There were 36 Phecodes that significantly differentiated the two groups. Youth who lived on farms had significantly higher odds of agricultural injury, dermatophytosis, spinal neuritis, and strabismus compared to non-farm youth. Remaining Phecodes indicated protection in the farm group. Notably, relative to the non-farm group, farm youth had a 20%-30% lower odds of respiratory illnesses, as well as 30%-40% lower odds of mental health and neurological conditions. Conclusion: This was the first known study to utilize a PheWAS approach to comprehensively compare medical comorbidities in farm versus non-farm youth. Findings confirmed the known injury hazards in farm youth, but there appeared to be more health benefits of living on farms. Some of these apparent protections were novel, particularly those related to affective disorders, but require future confirmatory testing to understand how care seeking behaviors may also influence farm and non-farm households. AN - cdc:258712 IS - 2 J2 - Journal of Agromedicine KW - Child KW - Family KW - Agriculture KW - Safety KW - Occupational Injuries KW - Occupational Health KW - Agricultural workers; Agriculture; Families; Farm workers; Children; Health effects; Injuries; KW - Author Keywords: Farm; health; PheWAS; Wisconsin; youth KW - Agriculture KW - Child KW - Family KW - Occupational Health KW - Occupational Injuries KW - Safety PY - 2026/04/01 T2 - Journal of Agromedicine T2 - J Agromedicine 2026 Apr; 31(2):254-262 TI - A PheWAS Analysis of the Risks and Benefits of Growing Up on a Farm VL - 31 UR - https://stacks.cdc.gov/view/cdc/258712 ER -
Adverse Childhood Experiences, Exposure to the World Trade Center Attacks, and Chronic Symptoms of Depression, PTSD, and Unhealthy Drinking

Parcesepe, Angela M. ;

Sanborn, Jenna

2026/02/01 | J Affect Disord 2026 Feb; 395(Pt A):120671 | National Institute for Occupational Safety and Health (NIOSH)

Background: Exposure to potentially traumatic events (PTE) is common and associated with poor mental health. Little is known about factors that influence the relationship between PTE and long-term mental health. Methods: This sample included 26,178 individuals who were 18 years or older on September 11, 2001, enrolled in the World Trade Center Heal ...

08/10/2026

Title : Adverse Childhood Experiences, Exposure to the World Trade Center Attacks, and Chronic Symptoms of Depression, PTSD, and Unhealthy Drinking Personal Author(s) : Parcesepe, Angela M.;Sanborn, Jenna;Sisti, Julia S.;Metzler, Janna; Published Date : 2026/02/01 Pages in Document : 9 pdf pages Source : J Affect Disord 2026 Feb; 395(Pt A):120671 URL : https://stacks.cdc.gov/view/cdc/258711 Journal Title : Journal of Affective Disorders
Parcesepe, Angela M. et al. (2026). Adverse Childhood Experiences, Exposure to the World Trade Center Attacks, and Chronic Symptoms of Depression, PTSD, and Unhealthy Drinking. Journal of Affective Disorders. 395

Parcesepe, Angela M. et al. "Adverse Childhood Experiences, Exposure to the World Trade Center Attacks, and Chronic Symptoms of Depression, PTSD, and Unhealthy Drinking" Journal of Affective Disorders 395 (2026)

Parcesepe, Angela M. et al. "Adverse Childhood Experiences, Exposure to the World Trade Center Attacks, and Chronic Symptoms of Depression, PTSD, and Unhealthy Drinking" Journal of Affective Disorders, vol. 395, 2026
Export RIS Citation Information. TY - Journal Article AU - Parcesepe, Angela M. AU - Sanborn, Jenna AU - Sisti, Julia S. AU - Metzler, Janna AB - Background: Exposure to potentially traumatic events (PTE) is common and associated with poor mental health. Little is known about factors that influence the relationship between PTE and long-term mental health. Methods: This sample included 26,178 individuals who were 18 years or older on September 11, 2001, enrolled in the World Trade Center Health Registry, and completed the Wave 5 survey in 2020-21. We investigated the extent to which adverse childhood events (ACE) modified the relationship between WTC-related PTE exposure and the risk of prevalent or persistent symptoms of post-traumatic stress disorder (PTSD), depression, and unhealthy drinking on multiplicative and additive scales. For each outcome, we fit a log-binomial regression model including categorical variables for WTC-related PTE and ACE, their interaction, and covariates. Adjusted risk ratios were estimated for each joint level of PTE and ACE, using the doubly unexposed group (medium/low PTE and no ACEs) as reference. Results: ACE exposure and WTC-related PTE exposure were independently associated with greater risk of prevalent and persistent symptoms of PTSD, depression, and unhealthy drinking. There was evidence of positive additive and negative multiplicative modification by ACE exposure of the relationship between WTC-related PTE exposure and symptoms of persistent PTSD and depression. Conclusion: Findings suggest that adverse experiences in childhood increase the risk and persistence of symptoms of PTSD and depression after mass trauma in adulthood. Screening of traumatic events throughout the life course may increase identification of individuals at increased risk of poor mental health outcomes following subsequent PTE exposure. AN - cdc:258711 J2 - Journal of Affective Disorders KW - Adverse Childhood Experiences KW - Safety KW - September 11 Terrorist Attacks KW - Occupational Health KW - Stress Disorders, Post-Traumatic KW - Mental Health KW - Mental health; Post-traumatic stress disorder; PTSD; WTC; World Trade Center; Traumatic incident stress; Alcohol; KW - Author Keywords: Trauma; Mental health; Adverse childhood events; Depression; Alcohol; PTSD KW - Adverse Childhood Experiences KW - Mental Health KW - Occupational Health KW - Safety KW - September 11 Terrorist Attacks KW - Stress Disorders, Post-Traumatic PY - 2026/02/01 T2 - Journal of Affective Disorders T2 - J Affect Disord 2026 Feb; 395(Pt A):120671 TI - Adverse Childhood Experiences, Exposure to the World Trade Center Attacks, and Chronic Symptoms of Depression, PTSD, and Unhealthy Drinking VL - 395 UR - https://stacks.cdc.gov/view/cdc/258711 ER -
Body Mass Index Is Associated with Functional Brain Network Efficiency in Midlife World Trade Center Responders with Cognitive Impairment

Zhang, Xinlan ;

Huang, Chuan

2025/11/17 | Discover Neurosci 2025 Nov; 20:22 | National Institute for Occupational Safety and Health (NIOSH)

Background: Higher body mass index (BMI) is associated with lowered risk of dementia in aging populations, possibly because it improves cognitive reserve in old age. Little is known about mechanisms implicated in reductions in vulnerability and less is known about implications of BMI in cognitively impaired (CI) individuals at midlife. Here, we exa ...

08/10/2026

Title : Body Mass Index Is Associated with Functional Brain Network Efficiency in Midlife World Trade Center Responders with Cognitive Impairment Personal Author(s) : Zhang, Xinlan;Huang, Chuan;Ying, Jia;Zhao, Tianyun;Clouston, Sean A. P.;Luft, Benjamin J.; Published Date : 2025/11/17 Pages in Document : 15 pdf pages Source : Discover Neurosci 2025 Nov; 20:22 URL : https://stacks.cdc.gov/view/cdc/258710 Journal Title : Discover Neuroscience
Zhang, Xinlan et al. (2025). Body Mass Index Is Associated with Functional Brain Network Efficiency in Midlife World Trade Center Responders with Cognitive Impairment. Discover Neuroscience. 20(22).

Zhang, Xinlan et al. "Body Mass Index Is Associated with Functional Brain Network Efficiency in Midlife World Trade Center Responders with Cognitive Impairment" Discover Neuroscience 20, no. 22 (2025)

Zhang, Xinlan et al. "Body Mass Index Is Associated with Functional Brain Network Efficiency in Midlife World Trade Center Responders with Cognitive Impairment" Discover Neuroscience, vol. 20, no. 22, 2025
Export RIS Citation Information. TY - Journal Article AU - Zhang, Xinlan AU - Huang, Chuan AU - Ying, Jia AU - Zhao, Tianyun AU - Clouston, Sean A. P. AU - Luft, Benjamin J. AB - Background: Higher body mass index (BMI) is associated with lowered risk of dementia in aging populations, possibly because it improves cognitive reserve in old age. Little is known about mechanisms implicated in reductions in vulnerability and less is known about implications of BMI in cognitively impaired (CI) individuals at midlife. Here, we examined whether BMI relates to functional brain network efficiency and cognition in a physically active cohort of midlife World Trade Center (WTC) responders with documented 9/11-related exposures, testing how systemic inflammatory burden and body composition jointly shape brain networks. Methods: Resting-state fMRI data from 99 WTC responders and 10 matched controls were analyzed. Functional cerebral network efficiency metrics included characteristic path length (CPL), clustering coefficients (CC), global efficiency (GE), and small-worldness (SWN), and were derived across proportional sparsity thresholds to enhance robustness. Multivariate models tested the effects of BMI, CI, and their interaction on network efficiency. Results: Higher BMI and CI were independently associated with cerebral network efficiency. A significant BMI × CI interaction was identified (CPL: p=0.024; SWN: p=0.010; GE: p=0.034), indicating that the positive association between BMI and network efficiency was strongest among cognitively impaired responders. Specifically, elevated BMI correlated with more integrated and efficient networks (e.g., shorter CPL and greater CC, GE, and SWN). Functional network efficiency metrics were modestly associated with attention and processing speed, but not with memory or visuospatial performance, suggesting selective relevance to cognitive domains vulnerable to early disruption. Conclusions: Consistent with hypotheses of cognitive reserve, this study provides novel evidence that functional brain network topology is influenced by BMI among cognitively impaired WTC responders. Findings highlight a complex interplay among systemic health, brain organization, and cognitive function at midlife. AN - cdc:258710 IS - 22 J2 - Discover Neuroscience KW - Nervous System KW - Body Mass Index KW - Safety KW - Cognition KW - September 11 Terrorist Attacks KW - Occupational Health KW - World Trade Center; WTC; Cognitive function; Body Mass Index; BMI; Aging; Cohort studies; Neurological system; Magnetic resonance imaging; MRI; First responders; KW - Author Keywords: Functional connectivity; Graph theory; Cognitive impairment; World trade center responders KW - Body Mass Index KW - Cognition KW - Nervous System KW - Occupational Health KW - Safety KW - September 11 Terrorist Attacks PY - 2025/11/17 T2 - Discover Neuroscience T2 - Discover Neurosci 2025 Nov; 20:22 TI - Body Mass Index Is Associated with Functional Brain Network Efficiency in Midlife World Trade Center Responders with Cognitive Impairment VL - 20 UR - https://stacks.cdc.gov/view/cdc/258710 ER -
A Personalized Automated System Designed to Assign Hazardous Noise Exposures to Tasks Among Agricultural Workers

Peters, Thomas M.

;

Griffis, Misha A.

2026/03/01 | J Occup Environ Hyg 2026 Mar; 23(3):133-141 | National Institute for Occupational Safety and Health (NIOSH)

Farming is a noisy occupation, resulting in a high prevalence of hearing loss among agricultural workers. The aim of this study was to improve the accuracy of an automatic algorithm designed to cluster individual sound events into tasks. This work is part of the HearSafe Study, which aimed to increase agricultural workers' use of hearing protection ...

08/10/2026

Title : A Personalized Automated System Designed to Assign Hazardous Noise Exposures to Tasks Among Agricultural Workers Personal Author(s) : Peters, Thomas M.;Griffis, Misha A.;Stroh, Oliver;Brown, Noah;Curnick, Jacqueline;Tatum, Marcus;McCullagh, Marjorie C.;Thomas, Geb; Published Date : 2026/03/01 Pages in Document : 10 pdf pages Source : J Occup Environ Hyg 2026 Mar; 23(3):133-141 URL : https://stacks.cdc.gov/view/cdc/258709 Journal Title : Journal of Occupational and Environmental Hygiene
Peters, Thomas M. et al. (2026). A Personalized Automated System Designed to Assign Hazardous Noise Exposures to Tasks Among Agricultural Workers. Journal of Occupational and Environmental Hygiene. 23(3).

Peters, Thomas M. et al. "A Personalized Automated System Designed to Assign Hazardous Noise Exposures to Tasks Among Agricultural Workers" Journal of Occupational and Environmental Hygiene 23, no. 3 (2026)

Peters, Thomas M. et al. "A Personalized Automated System Designed to Assign Hazardous Noise Exposures to Tasks Among Agricultural Workers" Journal of Occupational and Environmental Hygiene, vol. 23, no. 3, 2026
Export RIS Citation Information. TY - Journal Article AU - Peters, Thomas M. AU - Griffis, Misha A. AU - Stroh, Oliver AU - Brown, Noah AU - Curnick, Jacqueline AU - Tatum, Marcus AU - McCullagh, Marjorie C. AU - Thomas, Geb AB - Farming is a noisy occupation, resulting in a high prevalence of hearing loss among agricultural workers. The aim of this study was to improve the accuracy of an automatic algorithm designed to cluster individual sound events into tasks. This work is part of the HearSafe Study, which aimed to increase agricultural workers' use of hearing protection devices by providing personalized information on hazardous noise to workers. Participants in the study interacted with the HearSafe System: a small sound level meter, a website, and an algorithm to associate noise with tasks. They wore the sound level meter that recorded loud (≥ 80 dBA) sound "events," their location, and audio clips. They interacted with the website to view where and when participants were exposed to hazardous noises during the day. To simplify interpretation, an algorithm clustered individual sound events into tasks based on their proximity in time and location. The system's effectiveness hinges on the accuracy of this clustering algorithm. In Phase I, the accuracy was determined using parameters for time between events (2, 5, and 10 min) and distances between tasks (5, 9, and 18 m). In Phase II, the algorithm was refined to account for pauses in work and riding on equipment. Researchers manually clustered events into tasks by listening to the audio clips. Algorithm accuracy was measured as the percentage of events matching the manual clustering. The automating accuracy was improved from 57% with the base algorithm to 87% with the most accurate algorithm (p = 0.02; 10 min between events, 9 m average distance between tasks, and added the condition to combining consecutive tasks that were within 9 m of each other). Increased accuracy in identifying noisy tasks will improve the efficacy of the HearSafe System to communicate when and where use of hearing protection devices are needed among agricultural workers. AN - cdc:258709 IS - 3 J2 - Journal of Occupational and Environmental Hygiene KW - Agriculture KW - Safety KW - Ear Protective Devices KW - Occupational Health KW - Noise, Occupational KW - Agricultural workers; Exposure assessment; Noise exposure; Hearing protection; Automation; Algorithms; Noise measurement; Farm workers; KW - Author Keywords: Agricultural workers; exposure assessment; hearing protection devices; noise exposures KW - Agriculture KW - Ear Protective Devices KW - Noise, Occupational KW - Occupational Health KW - Safety PY - 2026/03/01 T2 - Journal of Occupational and Environmental Hygiene T2 - J Occup Environ Hyg 2026 Mar; 23(3):133-141 TI - A Personalized Automated System Designed to Assign Hazardous Noise Exposures to Tasks Among Agricultural Workers VL - 23 UR - https://stacks.cdc.gov/view/cdc/258709 ER -

Previous Page Previous

261 - 280 / 797

Next Page Next

Found an issue?

Send us an email at: