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Showing 1161 - 1180 of 1984 results

Hearing and Neurodevelopmental Outcomes Among Children With Congenital Cytomegalovirus.

Stout, Jordan C. ;

Leung, Jessica

August 2025 | International Journal of Pediatric Otorhinolaryngology, 2025, v. 195

Congenital cytomegalovirus (cCMV) infection is the most common congenital infection and the leading non-genetic cause of sensorineural hearing loss. We assessed demographics, clinical characteristics, hearing and neurodevelopmental outcomes by 6 years of age among U.S. children with possible cCMV.Retrospective cohort design.The Audiological and Gen ...

10/09/2026

Supporting Files

Title : Hearing and Neurodevelopmental Outcomes Among Children With Congenital Cytomegalovirus. Personal Author(s) : Stout, Jordan C.;Leung, Jessica;Kfoury, Peter;Germiller, John A.;Park, Albert H.;Lanzieri, Tatiana M.; Published Date : August 2025 Pages in Document : 112408 (14 pdf pages) Source : International Journal of Pediatric Otorhinolaryngology, 2025, v. 195 DOI : https://doi.org/10.1016/j.ijporl.2025.112408 Journal Title : International Journal of Pediatric Otorhinolaryngology
Stout, J. C., Leung, J., Kfoury, P., Germiller, J. A., Park, A. H., & Lanzieri, T. M. (2025). Hearing and Neurodevelopmental Outcomes Among Children With Congenital Cytomegalovirus. International Journal of Pediatric Otorhinolaryngology, 195. https://doi.org/10.1016/j.ijporl.2025.112408

Stout, Jordan C., Jessica Leung, Peter Kfoury, John A. Germiller, Albert H. Park, and Tatiana M. Lanzieri. "Hearing and Neurodevelopmental Outcomes Among Children With Congenital Cytomegalovirus." International Journal of Pediatric Otorhinolaryngology 195 (2025). https://doi.org/10.1016/j.ijporl.2025.112408.

Stout, Jordan C., et al. "Hearing and Neurodevelopmental Outcomes Among Children With Congenital Cytomegalovirus." International Journal of Pediatric Otorhinolaryngology, vol. 195, 2025. Stacks. https://doi.org/10.1016/j.ijporl.2025.112408.
Export RIS Citation Information. TY - Journal Article AU - Stout, Jordan C. AU - Leung, Jessica AU - Kfoury, Peter AU - Germiller, John A. AU - Park, Albert H. AU - Lanzieri, Tatiana M. AB - Congenital cytomegalovirus (cCMV) infection is the most common congenital infection and the leading non-genetic cause of sensorineural hearing loss. We assessed demographics, clinical characteristics, hearing and neurodevelopmental outcomes by 6 years of age among U.S. children with possible cCMV. AB - Retrospective cohort design. AB - The Audiological and Genetic Database (AudGenDB) includes 175,216 pediatric patients who underwent audiology, otology or genetic visits during 2006-2019 in Children's Hospital of Philadelphia, Vanderbilt Children's Hospital, or Boston Children's Hospital. AB - Children with possible cCMV were identified by diagnostic codes for cCMV infection and CMV disease up to 6 years of age. We examined clinical signs of cCMV during 0-45 days of birth and neurodevelopmental conditions (including hearing loss) up to 6 years of age. Hearing loss was defined as pure tone average or any frequency threshold ≥25 dB. AB - A total of 180 (0.1 %) children with possible cCMV were identified; 70 % had diagnosis codes after 45 days of life. The proportions of Black and Hispanic/Latino children comprised a higher proportion in the possible cCMV group compared to the non-cCMV group. Overall, 129 (72 %) children with possible cCMV had diagnoses codes for neurodevelopmental conditions, including hearing loss (56), communication delays (45) and cerebral palsy (22). Hearing loss was diagnosed at a median age of 2 (1-4) years. AB - Neurodevelopmental delays were common among children with possible cCMV included in this study. AudGenDB provides access to longitudinal outcomes for a large and diverse cohort that remains helpful in lieu of state-mandated screenings. AB - Author manuscript AN - cdc:261371 C4 - PMC12875388 DO - https://doi.org/10.1016/j.ijporl.2025.112408 J2 - International Journal of Pediatric Otorhinolaryngology KW - Retrospective Studies KW - Neurodevelopmental Disorders KW - Child KW - Cytomegalovirus Infections KW - Female KW - Infant KW - Male KW - Humans KW - Infant, Newborn KW - Hearing Loss, Sensorineural KW - Child, Preschool KW - Congenital Cytomegalovirus Infection KW - Sensorineural Hearing Loss KW - Neurodevelopmental Disorders KW - Pediatric Audiology KW - Hearing Loss, Bilateral KW - Hearing Loss, Unilateral KW - Neurological Sequelae KW - Humans KW - Cytomegalovirus Infections KW - Retrospective Studies KW - Female KW - Male KW - Child, Preschool KW - Infant KW - Child KW - Hearing Loss, Sensorineural KW - Infant, Newborn KW - Neurodevelopmental Disorders LA - eng PY - 2025 T2 - International Journal of Pediatric Otorhinolaryngology T2 - International Journal of Pediatric Otorhinolaryngology, 2025, v. 195 TI - Hearing and Neurodevelopmental Outcomes Among Children With Congenital Cytomegalovirus. VL - 195 UR - https://stacks.cdc.gov/view/cdc/261371 ER -
Progestin-only Contraception and Thrombosis: an Updated Systematic Review.

Tepper, Naomi K. ;

Nguyen, Antoinette T.

July 2026 | Contraception, 2026, v. 159

Evidence is limited on whether the use of progestin-only contraception (POC) is associated with the risk of thrombosis. Our objective was to update an earlier systematic review on POC and thrombosis risk.We searched for articles that examined risk of venous thromboembolism (VTE) (e.g., deep venous thrombosis or pulmonary embolism) or arterial throm ...

10/09/2026

Supporting Files

Title : Progestin-only Contraception and Thrombosis: an Updated Systematic Review. Personal Author(s) : Tepper, Naomi K.;Nguyen, Antoinette T.;Whiteman, Maura K.;Curtis, Kathryn M.; Published Date : July 2026 Pages in Document : 110978 (24 pdf pages) Source : Contraception, 2026, v. 159 DOI : https://doi.org/10.1016/j.contraception.2025.110978 Journal Title : Contraception
Tepper, N. K., Nguyen, A. T., Whiteman, M. K., & Curtis, K. M. (2026). Progestin-only Contraception and Thrombosis: an Updated Systematic Review. Contraception, 159. https://doi.org/10.1016/j.contraception.2025.110978

Tepper, Naomi K., Antoinette T. Nguyen, Maura K. Whiteman, and Kathryn M. Curtis. "Progestin-only Contraception and Thrombosis: an Updated Systematic Review." Contraception 159 (2026). https://doi.org/10.1016/j.contraception.2025.110978.

Tepper, Naomi K., et al. "Progestin-only Contraception and Thrombosis: an Updated Systematic Review." Contraception, vol. 159, 2026. Stacks. https://doi.org/10.1016/j.contraception.2025.110978.
Export RIS Citation Information. TY - Journal Article AU - Tepper, Naomi K. AU - Nguyen, Antoinette T. AU - Whiteman, Maura K. AU - Curtis, Kathryn M. AB - Evidence is limited on whether the use of progestin-only contraception (POC) is associated with the risk of thrombosis. Our objective was to update an earlier systematic review on POC and thrombosis risk. AB - We searched for articles that examined risk of venous thromboembolism (VTE) (e.g., deep venous thrombosis or pulmonary embolism) or arterial thromboembolism (ATE) (e.g., myocardial infarction or stroke) among women with thrombogenic conditions or characteristics or in the general population using POC, compared with women using nonhormonal or no contraception, published during February 1, 2016 through November 30, 2022. We also included articles from a previous systematic review, with articles published through January 2016. We assessed quality for each study and certainty of evidence for all outcomes. AB - Thirty-three articles met inclusion criteria; one was good quality, 20 were fair quality, and 12 were poor quality. Seven articles were newly identified, and 26 were included in the previous review. Risk of VTE, but not ATE, was generally elevated with depot medroxyprogesterone acetate (DMPA) use among women with certain thrombogenic conditions or characteristics (e.g., diabetes or postpartum) and women in the general population. Risks of VTE and ATE were generally not elevated with use of other POC, including levonorgestrel intrauterine devices, implants, or progestin-only pills. AB - Evidence suggests that risk of VTE, but not ATE, is increased with DMPA use compared with nonuse among women with certain thrombogenic conditions and women in the general population. Evidence does not suggest increased risk of VTE or ATE with use of other POC. While several studies examined thrombosis risk with POC use and thrombogenic conditions or characteristics, data are limited for individual conditions or characteristics and no evidence was identified for most conditions. The certainty of evidence is low or very low for all outcomes. AB - Use of DMPA might increase the risk of VTE among women with medical conditions associated with thrombosis and among women in the general population. Evidence does not suggest an increased risk of thrombosis with other POC. Further study is needed on safety of POC use by women with thrombogenic conditions. AB - Author manuscript AN - cdc:261370 C4 - PMC12381897 DO - https://doi.org/10.1016/j.contraception.2025.110978 J2 - Contraception KW - Thromboembolism KW - Systematic Review KW - Contraception KW - contraception KW - progestin-only contraception KW - thromboembolism KW - systematic review KW - Contraception KW - Thromboembolism KW - Systematic Review LA - eng PY - 2026 T2 - Contraception T2 - Contraception, 2026, v. 159 TI - Progestin-only Contraception and Thrombosis: an Updated Systematic Review. VL - 159 UR - https://stacks.cdc.gov/view/cdc/261370 ER -
Risk Factors For HCV Infection in Georgia: a Case-control Study.

Butsashvili, Maia ;

Kanchelashvili, Giorgi

May 2025 | Journal of Infection in Developing Countries, 2025, v. 19, no. 5

Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease, including cirrhosis and liver cancer. Prior studies in Georgia identified risk factors such as injection drug use (IDU), tattoos, dental cleanings, medical injections, and blood transfusion. This study explored risk factors associated with HCV seroconversion in Georgia.A ...

10/09/2026

Supporting Files

Title : Risk Factors For HCV Infection in Georgia: a Case-control Study. Personal Author(s) : Butsashvili, Maia;Kanchelashvili, Giorgi;Galdavadze, Ketevan;Tsereteli, Maia;Baliashvili, Davit;Handanagic, Senad;Armstrong, Paige A;Shadaker, Shaun;Kamkamidze, George; Published Date : May 2025 Pages in Document : 792-796 (8 pdf pages) Source : Journal of Infection in Developing Countries, 2025, v. 19, no. 5 DOI : https://doi.org/10.3855/jidc.20658 Journal Title : Journal of Infection in Developing Countries
Butsashvili, M., Kanchelashvili, G., Galdavadze, K., Tsereteli, M., Baliashvili, D., Handanagic, S., Armstrong, P. A., Shadaker, S., & Kamkamidze, G. (2025). Risk Factors For HCV Infection in Georgia: a Case-control Study. Journal of Infection in Developing Countries, 19(5). https://doi.org/10.3855/jidc.20658

Butsashvili, Maia, Giorgi Kanchelashvili, Ketevan Galdavadze, Maia Tsereteli, Davit Baliashvili, Senad Handanagic, Paige A Armstrong, Shaun Shadaker, and George Kamkamidze. "Risk Factors For HCV Infection in Georgia: a Case-control Study." Journal of Infection in Developing Countries 19, no. 5 (2025). https://doi.org/10.3855/jidc.20658.

Butsashvili, Maia, et al. "Risk Factors For HCV Infection in Georgia: a Case-control Study." Journal of Infection in Developing Countries, vol. 19, no. 5, 2025. Stacks. https://doi.org/10.3855/jidc.20658.
Export RIS Citation Information. TY - Journal Article AU - Butsashvili, Maia AU - Kanchelashvili, Giorgi AU - Galdavadze, Ketevan AU - Tsereteli, Maia AU - Baliashvili, Davit AU - Handanagic, Senad AU - Armstrong, Paige A AU - Shadaker, Shaun AU - Kamkamidze, George AB - Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease, including cirrhosis and liver cancer. Prior studies in Georgia identified risk factors such as injection drug use (IDU), tattoos, dental cleanings, medical injections, and blood transfusion. This study explored risk factors associated with HCV seroconversion in Georgia. AB - A case-control study was conducted among adults aged ≥ 18 years. A total of 299 Cases (persons who seroconverted after ≥ 2 screenings) and 436 controls (persons with ≥ 2 negative anti-HCV test results dated 90 to 364 days apart) were randomly selected from the national HCV screening database from January 2019 to November 2020. Data were collected through telephone interviews and analyzed using descriptive statistics and logistic regression. AB - Among 206/299 (68.9%) cases and 229/436 (52.5%) controls who agreed to participate, 53.8% were female and 60.5% were aged > 40 years. After adjusting for covariates, independent predictors of HCV seroconversion were age > 40 years (adjusted odds ratio [aOR] = 2.47, 95% confidence interval [CI]: 1.52-4.01), male sex (aOR = 2.12, 95% CI: 1.34-3.34), IDU (aOR = 26.24, 95% CI: 3.27-210.43), history of invasive medical procedure (aOR = 3.19, 95% CI: 1.96-5.19), ≥ 24 hours of hospitalization (aOR = 2.01, 95% CI: 1.12-3.59), and occupational performance of any invasive medical procedure (aOR = 2.70, 95% CI: 1.12-6.53). AB - Our findings suggest that HCV seroconversions in Georgia are associated with IDU, hospitalization, and invasive medical procedures. These identified risk factors provide opportunities to further improve the prevention of HCV infection in Georgia. AB - Author manuscript AN - cdc:261369 C4 - PMC12146773 DO - https://doi.org/10.3855/jidc.20658 IS - 5 J2 - Journal of Infection in Developing Countries KW - Adolescent KW - Female KW - Aged KW - Young Adult KW - Risk Factors KW - Seroconversion KW - Hepatitis C KW - Case-Control Studies KW - Male KW - Middle Aged KW - Humans KW - Georgia (Republic) KW - Hepacivirus KW - Substance Abuse, Intravenous KW - Adult KW - Hepatitis C KW - HCV transmission KW - injection drug use KW - invasive medical procedures KW - Georgia KW - Humans KW - Male KW - Female KW - Case-Control Studies KW - Risk Factors KW - Adult KW - Georgia (Republic) KW - Hepatitis C KW - Middle Aged KW - Young Adult KW - Hepacivirus KW - Substance Abuse, Intravenous KW - Seroconversion KW - Aged KW - Adolescent LA - eng PY - 2025 T2 - Journal of Infection in Developing Countries T2 - Journal of Infection in Developing Countries, 2025, v. 19, no. 5 TI - Risk Factors For HCV Infection in Georgia: a Case-control Study. VL - 19 UR - https://stacks.cdc.gov/view/cdc/261369 ER -
Human Papillomavirus Vaccine Effectiveness by Age, Age at Vaccination, and Timing of Vaccination Relative to Age at First Sex Among Men Who Have Sex With Men-Seattle, Washington, 2018 to 2020.

Buchbinder, Stephanie A. ;

Lin, John

October 2025 | Sexually Transmitted Diseases, 2025, v. 52, no. 10

We evaluated human papillomavirus (HPV) vaccine effectiveness (VE) against prevalent anal HPV among men who have sex with men (MSM) by age, age at vaccination, and age at vaccination relative to age at first sex.Residual anal specimens from 1092 MSM aged 18 to 45 years attending a Seattle, Washington, sexual health clinic in 2018 to 2020 were teste ...

10/09/2026

Supporting Files

Title : Human Papillomavirus Vaccine Effectiveness by Age, Age at Vaccination, and Timing of Vaccination Relative to Age at First Sex Among Men Who Have Sex With Men-Seattle, Washington, 2018 to 2020. Personal Author(s) : Buchbinder, Stephanie A.;Lin, John;Markowitz, Lauri E.;Hughes, James P.;Querec, Troy D.;Unger, Elizabeth R.;Dada, Damilola;Iqbal, Alfred;Golden, Matthew R.;Meites, Elissa;DeSisto, Carla L.;Winer, Rachel L.; Published Date : October 2025 Pages in Document : 631-640 (21 pdf pages) Source : Sexually Transmitted Diseases, 2025, v. 52, no. 10 DOI : https://doi.org/10.1097/OLQ.0000000000002192 Journal Title : Sexually Transmitted Diseases
Buchbinder, S. A., Lin, J., Markowitz, L. E., Hughes, J. P., Querec, T. D., Unger, E. R., Dada, D., Iqbal, A., Golden, M. R., Meites, E., DeSisto, C. L., & Winer, R. L. (2025). Human Papillomavirus Vaccine Effectiveness by Age, Age at Vaccination, and Timing of Vaccination Relative to Age at First Sex Among Men Who Have Sex With Men-Seattle, Washington, 2018 to 2020. Sexually Transmitted Diseases, 52(10). https://doi.org/10.1097/OLQ.0000000000002192

Buchbinder, Stephanie A., John Lin, Lauri E. Markowitz, James P. Hughes, Troy D. Querec, Elizabeth R. Unger, and Damilola Dada, et al.. "Human Papillomavirus Vaccine Effectiveness by Age, Age at Vaccination, and Timing of Vaccination Relative to Age at First Sex Among Men Who Have Sex With Men-Seattle, Washington, 2018 to 2020." Sexually Transmitted Diseases 52, no. 10 (2025). https://doi.org/10.1097/OLQ.0000000000002192.

Buchbinder, Stephanie A., et al. "Human Papillomavirus Vaccine Effectiveness by Age, Age at Vaccination, and Timing of Vaccination Relative to Age at First Sex Among Men Who Have Sex With Men-Seattle, Washington, 2018 to 2020." Sexually Transmitted Diseases, vol. 52, no. 10, 2025. Stacks. https://doi.org/10.1097/OLQ.0000000000002192.
Export RIS Citation Information. TY - Journal Article AU - Buchbinder, Stephanie A. AU - Lin, John AU - Markowitz, Lauri E. AU - Hughes, James P. AU - Querec, Troy D. AU - Unger, Elizabeth R. AU - Dada, Damilola AU - Iqbal, Alfred AU - Golden, Matthew R. AU - Meites, Elissa AU - DeSisto, Carla L. AU - Winer, Rachel L. AB - We evaluated human papillomavirus (HPV) vaccine effectiveness (VE) against prevalent anal HPV among men who have sex with men (MSM) by age, age at vaccination, and age at vaccination relative to age at first sex. AB - Residual anal specimens from 1092 MSM aged 18 to 45 years attending a Seattle, Washington, sexual health clinic in 2018 to 2020 were tested for 28 HPV types. Demographic, clinical, sexual behavioral, and HPV vaccination data were extracted from clinic and electronic medical records. We calculated adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs) for associations between vaccination (≥1 dose of any HPV vaccine) and quadrivalent HPV vaccine (4vHPV)-type infection, by age group (18-26, 27-35, 36-45 years), vaccination age (among age groups 18-26, 27-35 years), and vaccination age relative to first sex (among those 18-26 years). Analyses were adjusted for race and ethnicity, preexposure prophylaxis use for HIV prevention, and lifetime number of sex partners. Vaccine effectiveness was calculated as (1 - aPR) × 100. AB - Among persons aged 18 to 26 years, 4vHPV-type HPV prevalence was lower among those vaccinated before first sex (aPR, 0.12 [95% CI, 0.02-0.87]; VE, 88%) or at <18 years of age (aPR, 0.22 [95% CI, 0.07-0.68]; VE, 78%) versus unvaccinated, but no VE was observed in those vaccinated at 18 to 26 years of age. Among persons aged 27 to 35 years, 4vHPV-type HPV prevalence was lower among those vaccinated at 18 to 26 years of age versus unvaccinated (aPR, 0.56 [95% CI, 0.36-0.87]; VE, 44%). No VE was observed in persons aged 27 to 35 or 36 to 45 years who were vaccinated at >26 years of age. AB - Results highlight the importance of routine HPV vaccination in adolescence and support efforts to increase catch-up vaccination among MSM. AB - Author manuscript AN - cdc:261368 C4 - PMC12258699 DO - https://doi.org/10.1097/OLQ.0000000000002192 IS - 10 J2 - Sexually Transmitted Diseases KW - Adolescent KW - Vaccination KW - Papillomavirus Vaccines KW - Young Adult KW - Homosexuality, Male KW - Age Factors KW - Papillomaviridae KW - Papillomavirus Infections KW - Vaccine Efficacy KW - Prevalence KW - Male KW - Humans KW - Middle Aged KW - Adult KW - Sexual Behavior KW - Humans KW - Male KW - Adult KW - Papillomavirus Infections KW - Adolescent KW - Young Adult KW - Papillomavirus Vaccines KW - Homosexuality, Male KW - Middle Aged KW - Vaccination KW - Vaccine Efficacy KW - Age Factors KW - Prevalence KW - Sexual Behavior KW - Papillomaviridae LA - eng PY - 2025 T2 - Sexually Transmitted Diseases T2 - Sexually Transmitted Diseases, 2025, v. 52, no. 10 TI - Human Papillomavirus Vaccine Effectiveness by Age, Age at Vaccination, and Timing of Vaccination Relative to Age at First Sex Among Men Who Have Sex With Men-Seattle, Washington, 2018 to 2020. VL - 52 UR - https://stacks.cdc.gov/view/cdc/261368 ER -
Economic Burden of Fungal Diseases in the United States.

Benedict, Kaitlin ;

Gold, Jeremy A. W.

June 2025 | Medical Mycology, 2025, v. 63, no. 6

We conservatively estimated the annual US fungal disease-related economic burden as $19.4 billion, including direct medical costs ($13.4 billion) of hospitalizations (n = 133 555) and outpatient visits (n = 13.4 million), $1.7 billion from absenteeism, and $4.3 billion from deaths (n = 7288). These findings underscore the need for fungal disease su ...

10/09/2026

Supporting Files

Title : Economic Burden of Fungal Diseases in the United States. Personal Author(s) : Benedict, Kaitlin;Gold, Jeremy A. W.;Chiller, Tom;Lyman, Meghan; Published Date : June 2025 Pages in Document : myaf049(8 pdf pages) Source : Medical Mycology, 2025, v. 63, no. 6 DOI : https://doi.org/10.1093/mmy/myaf049 Journal Title : Medical Mycology
Benedict, K., Gold, J. A. W., Chiller, T., & Lyman, M. (2025). Economic Burden of Fungal Diseases in the United States. Medical Mycology, 63(6). https://doi.org/10.1093/mmy/myaf049

Benedict, Kaitlin, Jeremy A. W. Gold, Tom Chiller, and Meghan Lyman. "Economic Burden of Fungal Diseases in the United States." Medical Mycology 63, no. 6 (2025). https://doi.org/10.1093/mmy/myaf049.

Benedict, Kaitlin, et al. "Economic Burden of Fungal Diseases in the United States." Medical Mycology, vol. 63, no. 6, 2025. Stacks. https://doi.org/10.1093/mmy/myaf049.
Export RIS Citation Information. TY - Journal Article AU - Benedict, Kaitlin AU - Gold, Jeremy A. W. AU - Chiller, Tom AU - Lyman, Meghan AB - We conservatively estimated the annual US fungal disease-related economic burden as $19.4 billion, including direct medical costs ($13.4 billion) of hospitalizations (n = 133 555) and outpatient visits (n = 13.4 million), $1.7 billion from absenteeism, and $4.3 billion from deaths (n = 7288). These findings underscore the need for fungal disease surveillance, treatment, and prevention efforts. AB - Author manuscript AN - cdc:261367 C4 - PMC12281149 DO - https://doi.org/10.1093/mmy/myaf049 IS - 6 J2 - Medical Mycology KW - Adolescent KW - Female KW - Cost of Illness KW - Mycoses KW - Aged KW - Young Adult KW - Child KW - Aged, 80 and over KW - Infant KW - Hospitalization KW - Male KW - Humans KW - Middle Aged KW - Child, Preschool KW - Adult KW - Health Care Costs KW - mycoses KW - costs and cost analysis KW - outpatients KW - hospitalization KW - death KW - Humans KW - Mycoses KW - Cost of Illness KW - Health Care Costs KW - Middle Aged KW - Hospitalization KW - Adult KW - Male KW - Aged KW - Female KW - Young Adult KW - Adolescent KW - Child KW - Child, Preschool KW - Aged, 80 and over KW - Infant LA - eng PY - 2025 T2 - Medical Mycology T2 - Medical Mycology, 2025, v. 63, no. 6 TI - Economic Burden of Fungal Diseases in the United States. VL - 63 UR - https://stacks.cdc.gov/view/cdc/261367 ER -
Post-mortem Study of Endemic Human Coronaviruses (HCoV-NL63, OC43, 229E and HKU-1) in Deaths of Children Under Five in Low- and Middle-income Countries: Findings From the Child Health and Mortality Prevention Surveillance (CHAMPS) Study.

Baillie, Vicky ;

Dangor, Ziyaad

June 2025 | Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, 2025, v. 178

Endemic human coronaviruses (HCoV-229E, HKU1, NL63, and OC43) are common causes of mild or asymptomatic respiratory infections in children but are considered rare causes of death.We evaluated pediatric deaths from January 2017 through December 2022. A panel of experts determined the cause of death (CoD) by reviewing available data, including pathol ...

10/09/2026

Supporting Files

Title : Post-mortem Study of Endemic Human Coronaviruses (HCoV-NL63, OC43, 229E and HKU-1) in Deaths of Children Under Five in Low- and Middle-income Countries: Findings From the Child Health and Mortality Prevention Surveillance (CHAMPS) Study. Personal Author(s) : Baillie, Vicky;Dangor, Ziyaad;Blau, Dianna M.;Mahtab, Sana;du Toit, Jeanie;Assefa, Nega;Oundo, Joseph;Kidanemariam, Zelalem Teklemariam;Scott, J. Anthony G.;Ameh, Soter;Ogbuanu, Ikechukwu Udo;Ojulong, Julius;Bunn, James;Kotloff, Karen L.;Sow, Samba O.;Tapia, Milagritos D.;Keita, Adama Mamby;Garrine, Marcelino;Mandomando, Inacio;Varo, Rosauro;Xerinda, Elisio G.;Rakislova, Natalia;Alam, Muntasir;El Arifeen, Shams;Gurley, Emily S.;Hossain, Mohammad Zahid;Rahman, Afruna;Akelo, Victor;Onyango, Clayton;Onyango, Dickens;Mutevedzi, Portia C.;Whitney, Cynthia G.;Bassat, Quique;Madhi, Shabir A.; Published Date : June 2025 Pages in Document : 105804 (11 pdf pages) Source : Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, 2025, v. 178 DOI : https://doi.org/10.1016/j.jcv.2025.105804 Journal Title : Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
Baillie, V., Dangor, Z., Blau, D. M., Mahtab, S., du Toit, J., Assefa, N., Oundo, J., Kidanemariam, Z. T., Scott, J. A. G., Ameh, S., Ogbuanu, I. U., Ojulong, J., Bunn, J., Kotloff, K. L., Sow, S. O., Tapia, M. D., Keita, A. M., Garrine, M., Mandomando, I., ... Madhi, S. A. (2025). Post-mortem Study of Endemic Human Coronaviruses (HCoV-NL63, OC43, 229E and HKU-1) in Deaths of Children Under Five in Low- and Middle-income Countries: Findings From the Child Health and Mortality Prevention Surveillance (CHAMPS) Study. Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, 178. https://doi.org/10.1016/j.jcv.2025.105804

Baillie, Vicky, Ziyaad Dangor, Dianna M. Blau, Sana Mahtab, Jeanie du Toit, Nega Assefa, and Joseph Oundo, et al.. "Post-mortem Study of Endemic Human Coronaviruses (HCoV-NL63, OC43, 229E and HKU-1) in Deaths of Children Under Five in Low- and Middle-income Countries: Findings From the Child Health and Mortality Prevention Surveillance (CHAMPS) Study." Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology 178 (2025). https://doi.org/10.1016/j.jcv.2025.105804.

Baillie, Vicky, et al. "Post-mortem Study of Endemic Human Coronaviruses (HCoV-NL63, OC43, 229E and HKU-1) in Deaths of Children Under Five in Low- and Middle-income Countries: Findings From the Child Health and Mortality Prevention Surveillance (CHAMPS) Study." Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, vol. 178, 2025. Stacks. https://doi.org/10.1016/j.jcv.2025.105804.
Export RIS Citation Information. TY - Journal Article AU - Baillie, Vicky AU - Dangor, Ziyaad AU - Blau, Dianna M. AU - Mahtab, Sana AU - du Toit, Jeanie AU - Assefa, Nega AU - Oundo, Joseph AU - Kidanemariam, Zelalem Teklemariam AU - Scott, J. Anthony G. AU - Ameh, Soter AU - Ogbuanu, Ikechukwu Udo AU - Ojulong, Julius AU - Bunn, James AU - Kotloff, Karen L. AU - Sow, Samba O. AU - Tapia, Milagritos D. AU - Keita, Adama Mamby AU - Garrine, Marcelino AU - Mandomando, Inacio AU - Varo, Rosauro AU - Xerinda, Elisio G. AU - Rakislova, Natalia AU - Alam, Muntasir AU - El Arifeen, Shams AU - Gurley, Emily S. AU - Hossain, Mohammad Zahid AU - Rahman, Afruna AU - Akelo, Victor AU - Onyango, Clayton AU - Onyango, Dickens AU - Mutevedzi, Portia C. AU - Whitney, Cynthia G. AU - Bassat, Quique AU - Madhi, Shabir A. AB - Endemic human coronaviruses (HCoV-229E, HKU1, NL63, and OC43) are common causes of mild or asymptomatic respiratory infections in children but are considered rare causes of death. AB - We evaluated pediatric deaths from January 2017 through December 2022. A panel of experts determined the cause of death (CoD) by reviewing available data, including pathological and molecular findings from minimally invasive tissue sampling (lung tissues, blood, CSF, and nasopharyngeal swabs), clinical records, and verbal autopsies. AB - Endemic HCoV were detected in the respiratory samples of 3 % (n = 86/3357) of enrolled decedents: 1 % (n = 12/2043) of neonates, 5 % (n = 35/681) of infants and 6 % (n = 39/633) of children deaths. However, HCoVs were attributed as the CoD in only two cases - both involving young infants with underlying birth defects and severe wasting, who succumbed to polymicrobial hospital-acquired infections involving HCoV-OC43, Klebsiella pneumoniae, and Acinetobacter baumannii. Amongst the remaining 84 decedents in whom an HCoV was detected, 82 % (n = 69/84; median Ct of 25.34; range: 15.28-36.17) were deaths attributed to other infections, including 54 % (n = 32/69; median Ct of 23.86; range: 15.28-35.2) with lower respiratory infections determined to be the CoD. The bulk of these deaths (96 %, n = 66/69) were attributed to other pathogens - Plasmodium falciparum (27 %, n = 19/69), K. pneumoniae (23 %, n = 16/69), Streptococcus pneumoniae (20 %, n = 14/69), Escherichia coli (16 %, n = 11/69) and Cytomegalovirus (10 %, n = 7/69). AB - Although endemic HCoV was identified in children who died of respiratory infections, it was rarely attributed to being in the CoD. Nevertheless, further research is warranted to explore the potential role of HCoVs in LRTI pathogenesis and their impact on facilitating more pathogenic infections. AB - Author manuscript AN - cdc:261366 C4 - PMC13066964 DO - https://doi.org/10.1016/j.jcv.2025.105804 J2 - Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology KW - Female KW - Autopsy KW - Coronavirus OC43, Human KW - Respiratory Tract Infections KW - Coronavirus NL63, Human KW - Infant, Newborn KW - Coronavirus KW - Cause of Death KW - Coronavirus 229E, Human KW - Infant KW - Developing Countries KW - Coronavirus Infections KW - Male KW - Humans KW - Child, Preschool KW - Coronavirus KW - Child mortality KW - Cause of death KW - Minimally invasive tissue sampling KW - Humans KW - Infant KW - Coronavirus Infections KW - Child, Preschool KW - Infant, Newborn KW - Male KW - Female KW - Autopsy KW - Respiratory Tract Infections KW - Coronavirus KW - Cause of Death KW - Developing Countries KW - Coronavirus OC43, Human KW - Coronavirus NL63, Human KW - Coronavirus 229E, Human LA - eng PY - 2025 T2 - Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology T2 - Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, 2025, v. 178 TI - Post-mortem Study of Endemic Human Coronaviruses (HCoV-NL63, OC43, 229E and HKU-1) in Deaths of Children Under Five in Low- and Middle-income Countries: Findings From the Child Health and Mortality Prevention Surveillance (CHAMPS) Study. VL - 178 UR - https://stacks.cdc.gov/view/cdc/261366 ER -
Clinical and Sociodemographic Factors Associated With Ocular Mpox in California, May 2022 to September 2023.

Hanft, Wyatt ;

Saadeh, Kayla

November 2025 | Sexually Transmitted Diseases, 2025, v. 52, no. 11

Inoculation of the eye with monkeypox virus can cause vision-threatening disease necessitating hospitalization and urgent treatment. Ocular mpox is poorly understood, including who is most affected.We performed a cross-sectional study comparing ocular and non-ocular mpox cases reported to the California Department of Public Health from May 1, 2022, ...

10/09/2026

Supporting Files

Title : Clinical and Sociodemographic Factors Associated With Ocular Mpox in California, May 2022 to September 2023. Personal Author(s) : Hanft, Wyatt;Saadeh, Kayla;Snyder, Robert E.;Watson, Jessica;Tang, Eric C.;Chapman, Eric;Ramos, Marisa;Johnson, Kelly A.; Published Date : November 2025 Pages in Document : 684-689 (15 pdf pages) Source : Sexually Transmitted Diseases, 2025, v. 52, no. 11 DOI : https://doi.org/10.1097/OLQ.0000000000002195 Journal Title : Sexually Transmitted Diseases
Hanft, W., Saadeh, K., Snyder, R. E., Watson, J., Tang, E. C., Chapman, E., Ramos, M., & Johnson, K. A. (2025). Clinical and Sociodemographic Factors Associated With Ocular Mpox in California, May 2022 to September 2023. Sexually Transmitted Diseases, 52(11). https://doi.org/10.1097/OLQ.0000000000002195

Hanft, Wyatt, Kayla Saadeh, Robert E. Snyder, Jessica Watson, Eric C. Tang, Eric Chapman, Marisa Ramos, and Kelly A. Johnson. "Clinical and Sociodemographic Factors Associated With Ocular Mpox in California, May 2022 to September 2023." Sexually Transmitted Diseases 52, no. 11 (2025). https://doi.org/10.1097/OLQ.0000000000002195.

Hanft, Wyatt, et al. "Clinical and Sociodemographic Factors Associated With Ocular Mpox in California, May 2022 to September 2023." Sexually Transmitted Diseases, vol. 52, no. 11, 2025. Stacks. https://doi.org/10.1097/OLQ.0000000000002195.
Export RIS Citation Information. TY - Journal Article AU - Hanft, Wyatt AU - Saadeh, Kayla AU - Snyder, Robert E. AU - Watson, Jessica AU - Tang, Eric C. AU - Chapman, Eric AU - Ramos, Marisa AU - Johnson, Kelly A. AB - Inoculation of the eye with monkeypox virus can cause vision-threatening disease necessitating hospitalization and urgent treatment. Ocular mpox is poorly understood, including who is most affected. AB - We performed a cross-sectional study comparing ocular and non-ocular mpox cases reported to the California Department of Public Health from May 1, 2022, to September 30, 2023. χ2 and t tests were used to compare between-group sociodemographic characteristics, HIV status, and vaccine status. Bivariate and multivariate logistic regressions adjusting for HIV and race/ethnicity were used to calculate odds ratios and 95% confidence intervals for the association between JYNNEOS vaccination and ocular mpox. AB - Of 5878 mpox infections, 2403 (40.9%) had complete ocular symptom reporting and were included in this analysis. Of these, 260 (10.8%) were ocular cases. Among the 2403 included cases, most were cisgender men (94.6%) and reported male-to-male sexual contact (72.0%). The proportion of non-ocular versus ocular mpox cases differed significantly by race/ethnicity and HIV status ( P < 0.05), with more ocular cases being Hispanic/Latinx (50.8% vs. 41.8%), Black (14.2% vs. 8.9%), and with HIV (50.8% vs. 40.4%). After adjusting for race/ethnicity and HIV status, people with ≥1 dose of JYNNEOS had approximately half the odds of having ocular symptoms compared with people who were unvaccinated (adjusted odds ratio, 0.52; 95% confidence interval, 0.24-0.97). AB - A higher proportion of Black, Latinx, or people living with HIV had ocular mpox symptoms, suggesting that these groups may benefit from focused interventions to prevent infection and this complication. JYNNEOS before mpox exposure may protect against ocular complications, stressing the importance of vaccination to prevent severe sequelae, especially for vulnerable populations. AB - Author manuscript AN - cdc:261365 C4 - PMC12306453 DO - https://doi.org/10.1097/OLQ.0000000000002195 IS - 11 J2 - Sexually Transmitted Diseases KW - Adolescent KW - Female KW - Vaccination KW - Eye Infections, Viral KW - Racial Groups KW - Monkeypox virus KW - Young Adult KW - Cross-Sectional Studies KW - Ethnicity KW - Risk Factors KW - Male KW - Humans KW - Middle Aged KW - Sociodemographic Factors KW - Mpox, Monkeypox KW - Adult KW - HIV Infections KW - mpox KW - monkeypox KW - virus KW - ocular mpox KW - JYNNEOS vaccination KW - Adolescent KW - Adult KW - Female KW - Humans KW - Male KW - Middle Aged KW - Young Adult KW - Cross-Sectional Studies KW - Ethnicity KW - HIV Infections KW - Risk Factors KW - Sociodemographic Factors KW - Vaccination KW - Racial Groups KW - Mpox, Monkeypox KW - Monkeypox virus KW - Eye Infections, Viral LA - eng PY - 2025 T2 - Sexually Transmitted Diseases T2 - Sexually Transmitted Diseases, 2025, v. 52, no. 11 TI - Clinical and Sociodemographic Factors Associated With Ocular Mpox in California, May 2022 to September 2023. VL - 52 UR - https://stacks.cdc.gov/view/cdc/261365 ER -
Access to Language Interpretation Services at Health Care Facilities Providing Care to Adults Diagnosed With HIV in the United States, 2019.

Padilla, Mabel ;

Beer, Linda

January 1, 2026 | Current HIV Research, 2026, v. 23, no. 3

People with limited English proficiency (LEP) experience barriers to healthcare access and optimal outcomes. Language interpretation services can facilitate clear communication- which is key to effective HIV care and treatment.We analyzed weighted data from the 2019 cycle of the Medical Monitoring Project (MMP), a cross-sectional, complex sample su ...

10/09/2026

Supporting Files

Title : Access to Language Interpretation Services at Health Care Facilities Providing Care to Adults Diagnosed With HIV in the United States, 2019. Personal Author(s) : Padilla, Mabel;Beer, Linda;Luna-Gierke, Ruth E.;Tie, Tracy;Lu, Jen-Feng;Weiser, John; Published Date : January 1, 2026 Pages in Document : 203-213 (17 pdf pages) Source : Current HIV Research, 2026, v. 23, no. 3 DOI : https://doi.org/10.2174/011570162X362664250527051957 Journal Title : Current HIV Research
Padilla, M., Beer, L., Luna-Gierke, R. E., Tie, T., Lu, J. F., & Weiser, J. (2026). Access to Language Interpretation Services at Health Care Facilities Providing Care to Adults Diagnosed With HIV in the United States, 2019. Current HIV Research, 23(3). https://doi.org/10.2174/011570162X362664250527051957

Padilla, Mabel, Linda Beer, Ruth E. Luna-Gierke, Tracy Tie, Jen-Feng Lu, and John Weiser. "Access to Language Interpretation Services at Health Care Facilities Providing Care to Adults Diagnosed With HIV in the United States, 2019." Current HIV Research 23, no. 3 (2026). https://doi.org/10.2174/011570162X362664250527051957.

Padilla, Mabel, et al. "Access to Language Interpretation Services at Health Care Facilities Providing Care to Adults Diagnosed With HIV in the United States, 2019." Current HIV Research, vol. 23, no. 3, 2026. Stacks. https://doi.org/10.2174/011570162X362664250527051957.
Export RIS Citation Information. TY - Journal Article AU - Padilla, Mabel AU - Beer, Linda AU - Luna-Gierke, Ruth E. AU - Tie, Tracy AU - Lu, Jen-Feng AU - Weiser, John AB - People with limited English proficiency (LEP) experience barriers to healthcare access and optimal outcomes. Language interpretation services can facilitate clear communication- which is key to effective HIV care and treatment. AB - We analyzed weighted data from the 2019 cycle of the Medical Monitoring Project (MMP), a cross-sectional, complex sample survey of U.S. adults with diagnosed HIV, and data from the 2021 MMP Facility Survey, a survey of facilities providing care to 2019 MMP respondents. We estimated the percentage of people with HIV (PWH) with LEP who received care at facilities offering language interpretation services and facilities providing language interpretation services, overall and by selected characteristics. AB - Overall, 89.9% of PWH with LEP received care at a facility with language interpretation services, and 83.6% of facilities provided language interpretation services. PWH with LEP who were unemployed were less likely than those who were employed to receive care at a facility with language interpretation services. Facilities that were Federally Qualified Health Centers, were not private practices, received Ryan White HIV/AIDS Program funding, and accepted public health care coverage were more likely to provide language interpretation services than facilities without these characteristics. AB - Most PWH with LEP obtained HIV care at health care facilities providing language interpretation services, a positive finding as language is a common barrier to accessing care for people with LEP. Most facilities also provided language interpretation services, an important step towards ensuring meaningful access for people with LEP, as required by law. AB - Our findings demonstrate that most HIV care facilities are providing access to language services to PWH with LEP in the United States. AB - Author manuscript AN - cdc:261364 C4 - PMC12402997 DO - https://doi.org/10.2174/011570162X362664250527051957 IS - 3 J2 - Current HIV Research KW - Communication Barriers KW - Female KW - Limited English Proficiency KW - Young Adult KW - Cross-Sectional Studies KW - Surveys and Questionnaires KW - Language KW - Male KW - Middle Aged KW - Humans KW - Health Services Accessibility KW - Health Facilities KW - Adult KW - HIV Infections KW - HIV KW - language KW - limited English proficiency KW - communication KW - interpretation services KW - Good health and well-being KW - reduced inequalities KW - Humans KW - HIV Infections KW - Health Services Accessibility KW - Adult KW - Cross-Sectional Studies KW - Male KW - Female KW - Middle Aged KW - Health Facilities KW - Language KW - Limited English Proficiency KW - Communication Barriers KW - Young Adult KW - Surveys and Questionnaires LA - eng PY - 2026 T2 - Current HIV Research T2 - Current HIV Research, 2026, v. 23, no. 3 TI - Access to Language Interpretation Services at Health Care Facilities Providing Care to Adults Diagnosed With HIV in the United States, 2019. VL - 23 UR - https://stacks.cdc.gov/view/cdc/261364 ER -
Incidence of AIDS-Defining Conditions Among Adults With Perinatally Acquired HIV After Transition to Adult HIV Care in the United States and Canada, 2000-2022.

Haw, Nel Jason L. ;

Lesko, Catherine R.

December 24, 2025 | Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 81, no. 5

Little is known about the incidence of AIDS-defining conditions (ADCs) among people with perinatally acquired human immunodeficiency virus (PHIV) who transitioned to adult human immunodeficiency virus (HIV) care in the United States and Canada. We described the incidence among PHIV and compared it with that among those with non-perinatally acquired ...

10/09/2026

Supporting Files

Title : Incidence of AIDS-Defining Conditions Among Adults With Perinatally Acquired HIV After Transition to Adult HIV Care in the United States and Canada, 2000-2022. Personal Author(s) : Haw, Nel Jason L.;Lesko, Catherine R.;Ng, Derek K.;Lam, Jennifer O.;Gebo, Kelly;Sterling, Timothy R.;Rabkin, Charles S.;Li, Jun;Buchacz, Kate;Agwu, Allison;Althoff, Keri; Corporate Authors(s) : North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) Published Date : December 24, 2025 Pages in Document : 962-969 (15 pdf pages) Source : Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 81, no. 5 DOI : https://doi.org/10.1093/cid/ciaf300 Journal Title : Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Haw, N. J. L., Lesko, C. R., Ng, D. K., Lam, J. O., Gebo, K., Sterling, T. R., Rabkin, C. S., Li, J., Buchacz, K., Agwu, A., & Althoff, K. (2025). Incidence of AIDS-Defining Conditions Among Adults With Perinatally Acquired HIV After Transition to Adult HIV Care in the United States and Canada, 2000-2022. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 81(5). https://doi.org/10.1093/cid/ciaf300

Haw, Nel Jason L., Catherine R. Lesko, Derek K. Ng, Jennifer O. Lam, Kelly Gebo, Timothy R. Sterling, and Charles S. Rabkin, et al.. "Incidence of AIDS-Defining Conditions Among Adults With Perinatally Acquired HIV After Transition to Adult HIV Care in the United States and Canada, 2000-2022." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 81, no. 5 (2025). https://doi.org/10.1093/cid/ciaf300.

Haw, Nel Jason L., et al. "Incidence of AIDS-Defining Conditions Among Adults With Perinatally Acquired HIV After Transition to Adult HIV Care in the United States and Canada, 2000-2022." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, vol. 81, no. 5, 2025. Stacks. https://doi.org/10.1093/cid/ciaf300.
Export RIS Citation Information. TY - Journal Article AU - Haw, Nel Jason L. AU - Lesko, Catherine R. AU - Ng, Derek K. AU - Lam, Jennifer O. AU - Gebo, Kelly AU - Sterling, Timothy R. AU - Rabkin, Charles S. AU - Li, Jun AU - Buchacz, Kate AU - Agwu, Allison AU - Althoff, Keri A2 - North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) AB - Little is known about the incidence of AIDS-defining conditions (ADCs) among people with perinatally acquired human immunodeficiency virus (PHIV) who transitioned to adult human immunodeficiency virus (HIV) care in the United States and Canada. We described the incidence among PHIV and compared it with that among those with non-perinatally acquired HIV (non-PHIV) and across calendar era. AB - Using data from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) from 2000-2022, we estimated weighted mean cumulative counts (MCCs) of ADCs, comparing people with PHIV and non-PHIV acquisition risk groups aged 18-40 years engaged in adult HIV care. The weights accounted for differences in characteristics among HIV acquisition risk groups as well as informative censoring. We calculated 95% confidence intervals using bootstrapping. We stratified results before and after 2012, when the immediate start of antiretroviral therapy was first recommended. AB - There were 5429 ADCs among 22 950 people with HIV. Among those with PHIV, the MCC of ADCs by 3 years in adult HIV care was 26 per 100 persons (95% confidence interval, 15-40) in 2000-2011 and 16 per 100 (5-21) in 2012-2022. Within each calendar era, weighted MCCs of ADCs among people with PHIV were similar or lower than in non-PHIV groups. Within each HIV acquisition risk group, weighted MCCs of ADCs were lower in 2000-2011 than in 2012-2022. AB - People with PHIV who transitioned to adult HIV care did not experience a greater ADC incidence than those with non-PHIV. This emphasizes the importance of continued engagement in adult HIV care, as it provides critical opportunities for ADC prevention and management. AB - Author manuscript AN - cdc:261363 C4 - PMC12375960 DO - https://doi.org/10.1093/cid/ciaf300 IS - 5 J2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America KW - Adolescent KW - Cohort Studies KW - Female KW - Infectious Disease Transmission, Vertical KW - Incidence KW - Transition to Adult Care KW - Male KW - Humans KW - Young Adult KW - Adult KW - Acquired Immunodeficiency Syndrome KW - HIV Infections KW - HIV KW - perinatally acquired KW - AIDS-defining conditions KW - lifetime survivors KW - Humans KW - Adult KW - Incidence KW - Male KW - Female KW - Young Adult KW - Adolescent KW - HIV Infections KW - Transition to Adult Care KW - Acquired Immunodeficiency Syndrome KW - Cohort Studies KW - Infectious Disease Transmission, Vertical LA - eng PY - 2025 T2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America T2 - Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 2025, v. 81, no. 5 TI - Incidence of AIDS-Defining Conditions Among Adults With Perinatally Acquired HIV After Transition to Adult HIV Care in the United States and Canada, 2000-2022. VL - 81 UR - https://stacks.cdc.gov/view/cdc/261363 ER -
Placental Abruption and Perinatal Mortality: Abnormal Placentation and Spontaneous Abortion as Contributors to Left Truncation Bias.

Kinlaw, Alan C. ;

Graham, Hillary L.

February 2026 | Paediatric and Perinatal Epidemiology, 2026, v. 40, no. 2

Generally, studies in perinatal epidemiology restrict cohort entry to 20 weeks of gestation, but exposures and outcomes may occur earlier. This restriction may introduce left truncation bias.To examine the impact of left truncation bias when estimating the causal effect of abruption on perinatal mortality in the context of abnormal placentation, wi ...

10/09/2026

Supporting Files

Title : Placental Abruption and Perinatal Mortality: Abnormal Placentation and Spontaneous Abortion as Contributors to Left Truncation Bias. Personal Author(s) : Kinlaw, Alan C.;Graham, Hillary L.;Ananth, Cande V.; Published Date : February 2026 Pages in Document : 133-143 (18 pdf pages) Source : Paediatric and Perinatal Epidemiology, 2026, v. 40, no. 2 DOI : https://doi.org/10.1111/ppe.70010 Journal Title : Paediatric and Perinatal Epidemiology
Kinlaw, A. C., Graham, H. L., & Ananth, C. V. (2026). Placental Abruption and Perinatal Mortality: Abnormal Placentation and Spontaneous Abortion as Contributors to Left Truncation Bias. Paediatric and Perinatal Epidemiology, 40(2). https://doi.org/10.1111/ppe.70010

Kinlaw, Alan C., Hillary L. Graham, and Cande V. Ananth. "Placental Abruption and Perinatal Mortality: Abnormal Placentation and Spontaneous Abortion as Contributors to Left Truncation Bias." Paediatric and Perinatal Epidemiology 40, no. 2 (2026). https://doi.org/10.1111/ppe.70010.

Kinlaw, Alan C., et al. "Placental Abruption and Perinatal Mortality: Abnormal Placentation and Spontaneous Abortion as Contributors to Left Truncation Bias." Paediatric and Perinatal Epidemiology, vol. 40, no. 2, 2026. Stacks. https://doi.org/10.1111/ppe.70010.
Export RIS Citation Information. TY - Journal Article AU - Kinlaw, Alan C. AU - Graham, Hillary L. AU - Ananth, Cande V. AB - Generally, studies in perinatal epidemiology restrict cohort entry to 20 weeks of gestation, but exposures and outcomes may occur earlier. This restriction may introduce left truncation bias. AB - To examine the impact of left truncation bias when estimating the causal effect of abruption on perinatal mortality in the context of abnormal placentation, with spontaneous abortion (SAB) as a censoring event. AB - Through 80 Monte Carlo simulation scenarios based on realistic clinical assumptions, we estimated risk differences (RD), risk ratios (RR) and bias parameters for the abruption-perinatal mortality association. AB - Censoring by SAB ranged from 5.6% to 7.6% across simulation setups. The risk of mortality was overestimated in observable (left-truncated) data at ≥ 20 weeks compared to an unobservable cohort starting follow-up at placental implantation (conception cohort). Underestimation of risks was stronger among abruption pregnancies. RDs for the abruption-mortality association were biased by +1% to +3% among conceptions with normal implantation and by +5% to +43% among abnormal placentation. Due to the disproportionate underestimation of mortality among nonabruption pregnancies, RRs were overestimated by 1.1 to 1.2-fold for normal implantations and by 1.1 to 8.4-fold for abnormal implantations. AB - The findings of this simulation study highlight the critical importance of placentation in successful pregnancy. Abnormal placentation has profound consequences for unsuccessful pregnancies, remarkably increasing the risks of early losses, placental abruption and other obstetrical complications. This study underscores that left truncation can bias the abruption-perinatal mortality association, differentially by whether the placentation was normal or abnormal. However, defining the causal question regarding the abruption-perinatal mortality association requires consideration of the target population, which may include all conceptions. In studies of these effects, outcome follow-up capability may introduce left truncation bias. We do not prescribe one analytic approach to account for left truncation, but rather, the approach should be guided by the causal question. AB - Author manuscript AN - cdc:261362 C4 - PMC12353283 DO - https://doi.org/10.1111/ppe.70010 IS - 2 J2 - Paediatric and Perinatal Epidemiology KW - Pregnancy KW - Perinatal Mortality KW - Female KW - Bias KW - Abruptio Placentae KW - Placentation KW - Monte Carlo Method KW - Humans KW - Infant, Newborn KW - Abortion, Spontaneous KW - Placental abruption KW - Perinatal mortality KW - Abnormal placentation KW - Left truncation KW - Selection bias KW - Spontaneous abortion KW - Depletion of susceptible KW - Monte-Carlo simulation KW - abnormal placentation KW - depletion of susceptible KW - left truncation KW - Monte‐Carlo simulation KW - perinatal mortality KW - placental abruption KW - selection bias KW - spontaneous abortion KW - Humans KW - Female KW - Pregnancy KW - Abruptio Placentae KW - Abortion, Spontaneous KW - Perinatal Mortality KW - Infant, Newborn KW - Bias KW - Monte Carlo Method KW - Placentation LA - eng PY - 2026 T2 - Paediatric and Perinatal Epidemiology T2 - Paediatric and Perinatal Epidemiology, 2026, v. 40, no. 2 TI - Placental Abruption and Perinatal Mortality: Abnormal Placentation and Spontaneous Abortion as Contributors to Left Truncation Bias. VL - 40 UR - https://stacks.cdc.gov/view/cdc/261362 ER -
Prevalence and Impact of Social Risk in Patients With Inflammatory Bowel Diseases: National Estimates From the United States.

Kim, Seo Hyun ;

Qi, Yuchen

December 2025 | Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association, 2025, v. 23, no. 13

Social risks are individual-level factors associated with adverse health outcomes. We determined the prevalence and impact of social risks on healthcare use among patients with inflammatory bowel diseases (IBDs) in the United States.In the U.S. National Health Interview Survey 2023, we estimated social risks across 6 domains (food insecurity, finan ...

10/09/2026

Supporting Files

Title : Prevalence and Impact of Social Risk in Patients With Inflammatory Bowel Diseases: National Estimates From the United States. Personal Author(s) : Kim, Seo Hyun;Qi, Yuchen;Banegas, Matthew P.;Kappelman, Michael D.;Nguyen, Nghia H.;Boland, Brigid S.;Hernandez, Carlos Lago;Xu, Ronghui;Singh, Siddharth; Published Date : December 2025 Pages in Document : 2588-2596 (16 pdf pages) Source : Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association, 2025, v. 23, no. 13 DOI : https://doi.org/10.1016/j.cgh.2025.03.031 Journal Title : Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association
Kim, S. H., Qi, Y., Banegas, M. P., Kappelman, M. D., Nguyen, N. H., Boland, B. S., Hernandez, C. L., Xu, R., & Singh, S. (2025). Prevalence and Impact of Social Risk in Patients With Inflammatory Bowel Diseases: National Estimates From the United States. Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association, 23(13). https://doi.org/10.1016/j.cgh.2025.03.031

Kim, Seo Hyun, Yuchen Qi, Matthew P. Banegas, Michael D. Kappelman, Nghia H. Nguyen, Brigid S. Boland, Carlos Lago Hernandez, Ronghui Xu, and Siddharth Singh. "Prevalence and Impact of Social Risk in Patients With Inflammatory Bowel Diseases: National Estimates From the United States." Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association 23, no. 13 (2025). https://doi.org/10.1016/j.cgh.2025.03.031.

Kim, Seo Hyun, et al. "Prevalence and Impact of Social Risk in Patients With Inflammatory Bowel Diseases: National Estimates From the United States." Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association, vol. 23, no. 13, 2025. Stacks. https://doi.org/10.1016/j.cgh.2025.03.031.
Export RIS Citation Information. TY - Journal Article AU - Kim, Seo Hyun AU - Qi, Yuchen AU - Banegas, Matthew P. AU - Kappelman, Michael D. AU - Nguyen, Nghia H. AU - Boland, Brigid S. AU - Hernandez, Carlos Lago AU - Xu, Ronghui AU - Singh, Siddharth AB - Social risks are individual-level factors associated with adverse health outcomes. We determined the prevalence and impact of social risks on healthcare use among patients with inflammatory bowel diseases (IBDs) in the United States. AB - In the U.S. National Health Interview Survey 2023, we estimated social risks across 6 domains (food insecurity, financial hardship, housing instability, transportation needs, education and employment, discrimination) in adults with IBD. We evaluated the association between burden of social risk (0 of 6 domains [none], 1 of 6 domains [mild], 2 of 6 domains [moderate], and ≥3 of 6 domains [severe]), unplanned healthcare utilization (emergency department and/or hospitalization), and medication nonadherence, accounting for differences in age, sex, race/ethnicity, insurance, income, and comorbidities. AB - Of 572 people included in the survey (mean age 56 years; 57% female; 81% non-Hispanic White [NHW], 12.9% Hispanic), 64% (95% confidence interval [CI], 59%-69%) experienced social risk across 1 or more domains (food insecurity, 22%; financial hardship, 28%; housing instability, 14%; transportation needs, 9%; education and employment, 9%; discrimination, 41%). Prevalence of severe social risk was higher in racial and ethnic minority groups (non-Hispanic Black vs Hispanic vs NHW: 37% vs 28% vs 12%). A higher burden of social risk was associated with higher risk of unplanned healthcare utilization (severe vs none: odds ratio, 3.5; 95% CI, 1.2-10.2) and cost-related medication nonadherence (OR, 11.8; 95% CI, 2.7-52.1), after accounting for income and insurance status. AB - Social risks are prevalent in adults with IBD and negatively impact healthcare utilization and medication nonadherence. Efforts to routinely identify and address social risks in patients with IBD should be part of standard clinical care. AB - Author manuscript AN - cdc:261361 C4 - PMC12354202 DO - https://doi.org/10.1016/j.cgh.2025.03.031 IS - 13 J2 - Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association KW - Female KW - Aged KW - Inflammatory Bowel Diseases KW - Young Adult KW - Socioeconomic Factors KW - Patient Acceptance of Health Care KW - Risk Factors KW - Prevalence KW - Food Insecurity KW - Male KW - Humans KW - Middle Aged KW - Adult KW - Social determinants of health KW - health disparities KW - Crohn's disease KW - ulcerative colitis KW - financial toxicity KW - Humans KW - Female KW - Male KW - Middle Aged KW - Inflammatory Bowel Diseases KW - Prevalence KW - Adult KW - Aged KW - Patient Acceptance of Health Care KW - Food Insecurity KW - Young Adult KW - Socioeconomic Factors KW - Risk Factors LA - eng PY - 2025 T2 - Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association T2 - Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association, 2025, v. 23, no. 13 TI - Prevalence and Impact of Social Risk in Patients With Inflammatory Bowel Diseases: National Estimates From the United States. VL - 23 UR - https://stacks.cdc.gov/view/cdc/261361 ER -
Evaluating Water Competency Attainment Among Young Children.

Langendorfer, Stephen J ;

Ramos, William Dominic

June 2025 | Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, June 2025

Participation in swimming lessons may reduce drowning among young children (aged 1-5 years). We examined minimum and mean ages at which young children demonstrate components of unsupported water competency (without parent/instructor assistance) and the degree of improvement associated with different numbers of formal group swim lessons through two ...

10/09/2026

Supporting Files

Title : Evaluating Water Competency Attainment Among Young Children. Personal Author(s) : Langendorfer, Stephen J;Ramos, William Dominic;Beale-Tawfeeq, Angela;Harvey, Connie T;Moreland, Briana;Bleser, Julia A;Clemens, Tessa; Published Date : June 2025 Pages in Document : ip-2024 (15 pdf pages) Source : Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, June 2025 DOI : https://doi.org/10.1136/ip-2024-045365 Journal Title : Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
Langendorfer, S. J., Ramos, W. D., Beale-Tawfeeq, A., Harvey, C. T., Moreland, B., Bleser, J. A., & Clemens, T. (2025). Evaluating Water Competency Attainment Among Young Children. Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention. https://doi.org/10.1136/ip-2024-045365

Langendorfer, Stephen J, William Dominic Ramos, Angela Beale-Tawfeeq, Connie T Harvey, Briana Moreland, Julia A Bleser, and Tessa Clemens. "Evaluating Water Competency Attainment Among Young Children." Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention (2025). https://doi.org/10.1136/ip-2024-045365.

Langendorfer, Stephen J, et al. "Evaluating Water Competency Attainment Among Young Children." Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, 2025. Stacks. https://doi.org/10.1136/ip-2024-045365.
Export RIS Citation Information. TY - Journal Article AU - Langendorfer, Stephen J AU - Ramos, William Dominic AU - Beale-Tawfeeq, Angela AU - Harvey, Connie T AU - Moreland, Briana AU - Bleser, Julia A AU - Clemens, Tessa AB - Participation in swimming lessons may reduce drowning among young children (aged 1-5 years). We examined minimum and mean ages at which young children demonstrate components of unsupported water competency (without parent/instructor assistance) and the degree of improvement associated with different numbers of formal group swim lessons through two projects. AB - Young children were enrolled in swim instruction programmes offered by a nationally recognised organisation. In project 1, four to eight 30-minute formal group swim lessons were offered. Project 2 increased the number to 12-18 lessons. We observed and categorised pre-/post-lesson developmental levels of components of water competency. AB - Significant improvements from pre- to post-test were observed across all water competency components in both projects. During project 1, the youngest age category in which we observed unsupported water entry and water exit behaviours was 1-1.9 years. The youngest age category during which we observed unsupported breath control, back flotation/buoyancy and changing body orientation behaviours was 2-2.9 years old. The greatest improvement occurred in water exit, followed by breath control. Most children did not achieve unsupported water competency except in water entry and exit. Children achieved more advanced unsupported behaviours as age increased. Children enrolled in more lessons (12-18) acquired more components and more advanced levels of water competency than children in fewer lessons (4-8). AB - Although swim skills improved in both projects, more research is needed to determine the optimal number of swimming lessons and the best methods of teaching lessons to young children for most to reach unsupported water competency levels. AB - Author manuscript AN - cdc:261360 C4 - PMC13082352 DO - https://doi.org/10.1136/ip-2024-045365 J2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention KW - Child KW - Swimming / education KW - Swimming / injuries KW - Drowning / prevention & control KW - Swimming / education KW - Swimming / injuries KW - Drowning / prevention & control KW - Child LA - eng PY - 2025 T2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention T2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, June 2025 TI - Evaluating Water Competency Attainment Among Young Children. UR - https://stacks.cdc.gov/view/cdc/261360 ER -
Factors Associated With Cancer-related Pain Among Utah Cancer Survivors.

Codden, Rachel R. ;

Ofori-Atta, Blessing S.

June 5, 2025 | Journal of Cancer Survivorship: Research and Practice, June 2025

To identify clinical and sociodemographic factors associated with cancer-related pain among Utah cancer survivors 2-5 years after diagnosis.Participants include 2232 Utah cancer survivors diagnosed with invasive cancers at ages 18 + who responded to a probability-based sample survey administered by the Utah Cancer Registry from 2018 to 2023. Partic ...

10/09/2026

Supporting Files

Title : Factors Associated With Cancer-related Pain Among Utah Cancer Survivors. Personal Author(s) : Codden, Rachel R.;Ofori-Atta, Blessing S.;Carter, Marjorie E.;Herget, Kimberly A.;Doherty, Jennifer A.;Kirchhoff, Anne C.;Millar, Morgan M.; Published Date : June 5, 2025 Pages in Document : 19 pdf pages Source : Journal of Cancer Survivorship: Research and Practice, June 2025 DOI : https://doi.org/10.1007/s11764-025-01840-2 Journal Title : Journal of Cancer Survivorship: Research and Practice
Codden, R. R., Ofori-Atta, B. S., Carter, M. E., Herget, K. A., Doherty, J. A., Kirchhoff, A. C., & Millar, M. M. (2025). Factors Associated With Cancer-related Pain Among Utah Cancer Survivors. Journal of Cancer Survivorship: Research and Practice. https://doi.org/10.1007/s11764-025-01840-2

Codden, Rachel R., Blessing S. Ofori-Atta, Marjorie E. Carter, Kimberly A. Herget, Jennifer A. Doherty, Anne C. Kirchhoff, and Morgan M. Millar. "Factors Associated With Cancer-related Pain Among Utah Cancer Survivors." Journal of Cancer Survivorship: Research and Practice (2025). https://doi.org/10.1007/s11764-025-01840-2.

Codden, Rachel R., et al. "Factors Associated With Cancer-related Pain Among Utah Cancer Survivors." Journal of Cancer Survivorship: Research and Practice, 2025. Stacks. https://doi.org/10.1007/s11764-025-01840-2.
Export RIS Citation Information. TY - Journal Article AU - Codden, Rachel R. AU - Ofori-Atta, Blessing S. AU - Carter, Marjorie E. AU - Herget, Kimberly A. AU - Doherty, Jennifer A. AU - Kirchhoff, Anne C. AU - Millar, Morgan M. AB - To identify clinical and sociodemographic factors associated with cancer-related pain among Utah cancer survivors 2-5 years after diagnosis. AB - Participants include 2232 Utah cancer survivors diagnosed with invasive cancers at ages 18 + who responded to a probability-based sample survey administered by the Utah Cancer Registry from 2018 to 2023. Participants self-reported cancer-related pain status and methods of pain control. We calculated counts and percentages and used logistic regression to identify sociodemographic and clinical factors associated with cancer-related pain. All analyses were weighted to account for complex survey sample design and age-adjusted to the Utah cancer survivor population. AB - Twenty-two percent of survivors reported currently experiencing physical pain caused by their cancer or cancer treatment. Of those reporting pain, 24% reported their pain was not under control, 40% indicated their pain was under control with medication, and 36% reported it was under control without medication. The most frequently used pain control methods were nonopioid analgesics (49%) and physical activity (37%). In multivariable models, younger survivors, those either underweight or obese, survivors of breast cancer, and those facing material financial hardships were more likely to report cancer-related pain. AB - Twenty-two percent of Utah cancer survivors experienced pain related to their cancer or cancer treatment. For some, this pain is well managed, but approximately a quarter have uncontrolled pain. AB - Cancer-related pain is not solely associated with clinical features, and the findings here can guide clinicians and researchers toward a better understanding of the needs of cancer survivors and tailor pain management treatments to this unique population. AB - Author manuscript AN - cdc:261359 C4 - PMC12211117 DO - https://doi.org/10.1007/s11764-025-01840-2 J2 - Journal of Cancer Survivorship: Research and Practice KW - Analgesics KW - Cancer Survivors KW - Chronic Pain KW - Neoplasms KW - Quality of Life KW - Pain Management KW - cancer survivor KW - chronic pain KW - social determinants of health KW - cancer KW - Cancer Survivors KW - Chronic Pain KW - Pain Management KW - Quality of Life KW - Neoplasms KW - Analgesics LA - eng PY - 2025 T2 - Journal of Cancer Survivorship: Research and Practice T2 - Journal of Cancer Survivorship: Research and Practice, June 2025 TI - Factors Associated With Cancer-related Pain Among Utah Cancer Survivors. UR - https://stacks.cdc.gov/view/cdc/261359 ER -
Are we Ending the HIV Epidemic Among Persons Who Inject Drugs?: Key Findings From 19 US Cities.

Baugher, Amy R. ;

Wejnert, Cyprian

October 2025 | AIDS (London, England), 2025, v. 39, no. 12

National HIV Behavioral Surveillance (NHBS) conducts surveillance among key populations, including persons who inject drugs (PWID). NHBS data can be used to monitor progress toward national goals, including Ending the HIV Epidemic (EHE). EHE strategies include HIV testing (Diagnose), rapid linkage to HIV treatment (Treat), and increasing access to ...

10/09/2026

Supporting Files

Title : Are we Ending the HIV Epidemic Among Persons Who Inject Drugs?: Key Findings From 19 US Cities. Personal Author(s) : Baugher, Amy R.;Wejnert, Cyprian;Kanny, Dafna;Broz, Dita;Feelemyer, Jonathan;Hershow, Rebecca B.;Burnett, Janet;Chapin-Bardales, Johanna;Haynes, Maya;Finlayson, Teresa;Prejean, Joseph; Published Date : October 2025 Pages in Document : 1813-1819 (12 pdf pages) Source : AIDS (London, England), 2025, v. 39, no. 12 DOI : https://doi.org/10.1097/QAD.0000000000004249 Journal Title : AIDS (London, England)
Baugher, A. R., Wejnert, C., Kanny, D., Broz, D., Feelemyer, J., Hershow, R. B., Burnett, J., Chapin-Bardales, J., Haynes, M., Finlayson, T., & Prejean, J. (2025). Are we Ending the HIV Epidemic Among Persons Who Inject Drugs?: Key Findings From 19 US Cities. AIDS (London, England), 39(12). https://doi.org/10.1097/QAD.0000000000004249

Baugher, Amy R., Cyprian Wejnert, Dafna Kanny, Dita Broz, Jonathan Feelemyer, Rebecca B. Hershow, and Janet Burnett, et al.. "Are we Ending the HIV Epidemic Among Persons Who Inject Drugs?: Key Findings From 19 US Cities." AIDS (London, England) 39, no. 12 (2025). https://doi.org/10.1097/QAD.0000000000004249.

Baugher, Amy R., et al. "Are we Ending the HIV Epidemic Among Persons Who Inject Drugs?: Key Findings From 19 US Cities." AIDS (London, England), vol. 39, no. 12, 2025. Stacks. https://doi.org/10.1097/QAD.0000000000004249.
Export RIS Citation Information. TY - Journal Article AU - Baugher, Amy R. AU - Wejnert, Cyprian AU - Kanny, Dafna AU - Broz, Dita AU - Feelemyer, Jonathan AU - Hershow, Rebecca B. AU - Burnett, Janet AU - Chapin-Bardales, Johanna AU - Haynes, Maya AU - Finlayson, Teresa AU - Prejean, Joseph AB - National HIV Behavioral Surveillance (NHBS) conducts surveillance among key populations, including persons who inject drugs (PWID). NHBS data can be used to monitor progress toward national goals, including Ending the HIV Epidemic (EHE). EHE strategies include HIV testing (Diagnose), rapid linkage to HIV treatment (Treat), and increasing access to preexposure prophylaxis (PrEP), and syringe services programs (SSPs) (Prevent). This analysis aimed to concisely compare NHBS key findings among PWID to EHE goals. AB - Cross-sectional NHBS data were collected from PWID in 2018 ( n = 9786) and 2022 ( n = 6574) in 19 US cities. We compared key findings from 2022 NHBS to specified EHE goals for Diagnose (HIV testing) and Treat (linkage to care, current antiretroviral therapy (ART) use) or 2018 NHBS key findings for Prevent (PrEP and SSP use). AB - In 2022, 45% of PWID were tested for HIV; 45% of PWID with HIV were linked to care within 1 month of diagnosis, and 79% were currently taking ART; 1% of PWID without HIV used PrEP; and approximately half of all PWID received syringes from an SSP. PrEP and SSP use among PWID have not changed since 2018. AB - National HIV strategies are not yet adequately reaching PWID. To end the US HIV epidemic, multilevel solutions are needed to tailor interventions for PWID and dismantle barriers to testing, treatment, and prevention. Structural solutions to improve access to basic needs and SSPs may have downstream benefits across the EHE strategies. AB - Author manuscript AN - cdc:261358 C4 - PMC12424270 DO - https://doi.org/10.1097/QAD.0000000000004249 IS - 12 J2 - AIDS (London, England) KW - Adolescent KW - Female KW - Needle-Exchange Programs KW - Epidemics KW - Young Adult KW - Pre-Exposure Prophylaxis KW - Cross-Sectional Studies KW - Drug Users KW - Male KW - Humans KW - Middle Aged KW - Substance Abuse, Intravenous KW - Adult KW - Disease Transmission, Infectious KW - HIV Infections KW - Ending the HIV Epidemic KW - national indicators KW - persons who inject drugs KW - surveillance KW - HIV KW - Humans KW - HIV Infections KW - Substance Abuse, Intravenous KW - Cross-Sectional Studies KW - Male KW - Female KW - Epidemics KW - Adult KW - Middle Aged KW - Needle-Exchange Programs KW - Young Adult KW - Pre-Exposure Prophylaxis KW - Adolescent KW - Disease Transmission, Infectious KW - Drug Users LA - eng PY - 2025 T2 - AIDS (London, England) T2 - AIDS (London, England), 2025, v. 39, no. 12 TI - Are we Ending the HIV Epidemic Among Persons Who Inject Drugs?: Key Findings From 19 US Cities. VL - 39 UR - https://stacks.cdc.gov/view/cdc/261358 ER -
Breast, Cervical, and Colorectal Cancer Screening Prevalence in the US-Affiliated Pacific Islands.

Gopalani, Sameer V. ;

Qin, Jin

August 2025 | Cancer Epidemiology, 2025, v. 97

Breast, cervical, and colorectal cancer screening are recommended and can reduce mortality from these cancers, yet information on screening prevalence in the US-Affiliated Pacific Islands (USAPI) is limited.We analyzed data from population-based cross-sectional surveys undertaken at different time points from 2016 to 2019 in American Samoa, the Com ...

10/09/2026

Supporting Files

Title : Breast, Cervical, and Colorectal Cancer Screening Prevalence in the US-Affiliated Pacific Islands. Personal Author(s) : Gopalani, Sameer V.;Qin, Jin;Buenconsejo-Lum, Lee;Thompson, Trevor D.;Miller, Jacqueline W.;Luther, X.-ner;Reichhardt, Martina;Senkomago, Virginia;Palafox, Neal A.;Kabua, Neiar;Ikerdeu, Edolem;Cash McGinley, Haley L.; Published Date : August 2025 Pages in Document : 102851 (17 pdf pages) Source : Cancer Epidemiology, 2025, v. 97 DOI : https://doi.org/10.1016/j.canep.2025.102851 Journal Title : Cancer Epidemiology
Gopalani, S. V., Qin, J., Buenconsejo-Lum, L., Thompson, T. D., Miller, J. W., Luther, X. n., Reichhardt, M., Senkomago, V., Palafox, N. A., Kabua, N., Ikerdeu, E., & Cash McGinley, H. L. (2025). Breast, Cervical, and Colorectal Cancer Screening Prevalence in the US-Affiliated Pacific Islands. Cancer Epidemiology, 97. https://doi.org/10.1016/j.canep.2025.102851

Gopalani, Sameer V., Jin Qin, Lee Buenconsejo-Lum, Trevor D. Thompson, Jacqueline W. Miller, X.-ner Luther, and Martina Reichhardt, et al.. "Breast, Cervical, and Colorectal Cancer Screening Prevalence in the US-Affiliated Pacific Islands." Cancer Epidemiology 97 (2025). https://doi.org/10.1016/j.canep.2025.102851.

Gopalani, Sameer V., et al. "Breast, Cervical, and Colorectal Cancer Screening Prevalence in the US-Affiliated Pacific Islands." Cancer Epidemiology, vol. 97, 2025. Stacks. https://doi.org/10.1016/j.canep.2025.102851.
Export RIS Citation Information. TY - Journal Article AU - Gopalani, Sameer V. AU - Qin, Jin AU - Buenconsejo-Lum, Lee AU - Thompson, Trevor D. AU - Miller, Jacqueline W. AU - Luther, X.-ner AU - Reichhardt, Martina AU - Senkomago, Virginia AU - Palafox, Neal A. AU - Kabua, Neiar AU - Ikerdeu, Edolem AU - Cash McGinley, Haley L. AB - Breast, cervical, and colorectal cancer screening are recommended and can reduce mortality from these cancers, yet information on screening prevalence in the US-Affiliated Pacific Islands (USAPI) is limited. AB - We analyzed data from population-based cross-sectional surveys undertaken at different time points from 2016 to 2019 in American Samoa, the Commonwealth of the Northern Mariana Islands, the Republic of Palau, the Republic of the Marshall Islands, and the Federated States of Micronesia states of Pohnpei and Kosrae. We estimated the age-standardized percentage of never screened and up-to-date screening for breast, cervical, and colorectal cancer among eligible adults by select sociodemographic and health characteristics. AB - In the USAPI overall, 20.6 % (95 % confidence interval [CI]: 18.6, 22.8) of participants were up-to-date with breast cancer screening, 38.6 % (95 % CI: 37.1, 40.2) with cervical cancer screening, and 15.1 % (95 % CI: 13.8, 16.4) with colorectal cancer screening. Screening in the USAPI overall was lower for all three cancers among participants who reported having a high school education or less compared to those with more than a high school education. Cervical cancer screening was lower among participants with diabetes compared to those without diabetes, and colorectal cancer screening was lower among participants who reported tobacco use than among those without tobacco use. AB - Cancer screening was suboptimal across all three cancer types in the USAPI. Developing, implementing, or expanding culturally tailored and effective cancer screening strategies may address barriers to screening and improve access and utilization. AB - Author manuscript AN - cdc:261357 C4 - PMC12284899 DO - https://doi.org/10.1016/j.canep.2025.102851 J2 - Cancer Epidemiology KW - Female KW - Colorectal Neoplasms KW - Mass Screening KW - Aged KW - Early Detection of Cancer KW - Young Adult KW - Breast Neoplasms KW - Uterine Cervical Neoplasms KW - Cross-Sectional Studies KW - Prevalence KW - Male KW - Humans KW - Middle Aged KW - Adult KW - breast cancer KW - cancer screening KW - cervical cancer KW - colorectal cancer KW - screening disparities KW - Pacific Islands KW - Humans KW - Female KW - Colorectal Neoplasms KW - Uterine Cervical Neoplasms KW - Middle Aged KW - Early Detection of Cancer KW - Male KW - Breast Neoplasms KW - Prevalence KW - Cross-Sectional Studies KW - Adult KW - Aged KW - Mass Screening KW - Young Adult LA - eng PY - 2025 T2 - Cancer Epidemiology T2 - Cancer Epidemiology, 2025, v. 97 TI - Breast, Cervical, and Colorectal Cancer Screening Prevalence in the US-Affiliated Pacific Islands. VL - 97 UR - https://stacks.cdc.gov/view/cdc/261357 ER -
The LEADING Guideline: Reporting Standards For Expert Panel, Best-estimate Diagnosis, and Longitudinal Expert All Data (LEAD) Methods.

Eijsbroek, Veerle C. ;

Kjell, Katarina

August 2025 | Comprehensive Psychiatry, 2025, v. 141

Accurate assessments of symptoms and illnesses are essential for health research and clinical practice but face many challenges. The absence of a single error-free measure is currently addressed by assessment methods involving experts reviewing several sources of information to achieve a best-estimate assessment. This assessment method is called th ...

10/09/2026

Supporting Files

Title : The LEADING Guideline: Reporting Standards For Expert Panel, Best-estimate Diagnosis, and Longitudinal Expert All Data (LEAD) Methods. Personal Author(s) : Eijsbroek, Veerle C.;Kjell, Katarina;Andrew Schwartz, H.;Boehnke, Jan R.;Fried, Eiko I.;Klein, Daniel N.;Gustafsson, Peik;Augenstein, Isabelle;Bossuyt, Patrick M.M.;Kjell, Oscar N.E.; Published Date : August 2025 Pages in Document : 152603 (25 pdf pages) Source : Comprehensive Psychiatry, 2025, v. 141 DOI : https://doi.org/10.1016/j.comppsych.2025.152603 Journal Title : Comprehensive Psychiatry
Eijsbroek, V. C., Kjell, K., Andrew Schwartz, H., Boehnke, J. R., Fried, E. I., Klein, D. N., Gustafsson, P., Augenstein, I., Bossuyt, P. M., & Kjell, O. N. (2025). The LEADING Guideline: Reporting Standards For Expert Panel, Best-estimate Diagnosis, and Longitudinal Expert All Data (LEAD) Methods. Comprehensive Psychiatry, 141. https://doi.org/10.1016/j.comppsych.2025.152603

Eijsbroek, Veerle C., Katarina Kjell, H. Andrew Schwartz, Jan R. Boehnke, Eiko I. Fried, Daniel N. Klein, Peik Gustafsson, Isabelle Augenstein, Patrick M.M. Bossuyt, and Oscar N.E. Kjell. "The LEADING Guideline: Reporting Standards For Expert Panel, Best-estimate Diagnosis, and Longitudinal Expert All Data (LEAD) Methods." Comprehensive Psychiatry 141 (2025). https://doi.org/10.1016/j.comppsych.2025.152603.

Eijsbroek, Veerle C., et al. "The LEADING Guideline: Reporting Standards For Expert Panel, Best-estimate Diagnosis, and Longitudinal Expert All Data (LEAD) Methods." Comprehensive Psychiatry, vol. 141, 2025. Stacks. https://doi.org/10.1016/j.comppsych.2025.152603.
Export RIS Citation Information. TY - Journal Article AU - Eijsbroek, Veerle C. AU - Kjell, Katarina AU - Andrew Schwartz, H. AU - Boehnke, Jan R. AU - Fried, Eiko I. AU - Klein, Daniel N. AU - Gustafsson, Peik AU - Augenstein, Isabelle AU - Bossuyt, Patrick M.M. AU - Kjell, Oscar N.E. AB - Accurate assessments of symptoms and illnesses are essential for health research and clinical practice but face many challenges. The absence of a single error-free measure is currently addressed by assessment methods involving experts reviewing several sources of information to achieve a best-estimate assessment. This assessment method is called the Expert Panel method in medicine, and the Best-Estimate Diagnosis or Longitudinal Expert All Data (LEAD) method in psychiatry and psychology. However, due to poor reporting of the assessment methods, the quality of pro-claimed best-estimate assessments is typically difficult to evaluate, and when the method is reported, the reporting quality varies substantially. To tackle this gap, we have developed a reporting guideline following a four-stage approach: 1) drafting reporting standards accompanied by empirical evidence, which were further developed with a patient organization for depression, 2) incorporating expert feedback through a two-round Delphi procedure, 3) refining the guideline based on an expert consensus meeting, and 4) testing the guideline by i) having researchers test it and ii) applying it to previously published studies. The last step also provides evidence for the need for the guideline: 10-63 % (Mean 33 %) of the standards were not reported across thirty randomly selected published studies. The result is the LEADING guideline comprising 20 reporting standards in four groups: the Longitudinal design, the Appropriate data, the Evaluation - experts, materials and procedures, and the Validity group. We hope that the LEADING guideline will assist researchers in planning, conducting, reporting, and evaluating research aiming to achieve best-estimate assessments. AB - Author manuscript AN - cdc:261356 C4 - PMC12584586 DO - https://doi.org/10.1016/j.comppsych.2025.152603 J2 - Comprehensive Psychiatry KW - Mental Disorders KW - Longitudinal Studies KW - Guidelines as Topic KW - Delphi Technique KW - Humans KW - Psychiatry KW - Research Design KW - Reporting KW - Assessment KW - Expert panel KW - Longitudinal Expert All Data KW - Best-estimate diagnosis KW - Standard KW - Psychiatry KW - Humans KW - Mental Disorders KW - Psychiatry KW - Delphi Technique KW - Research Design KW - Guidelines as Topic KW - Longitudinal Studies LA - eng PY - 2025 T2 - Comprehensive Psychiatry T2 - Comprehensive Psychiatry, 2025, v. 141 TI - The LEADING Guideline: Reporting Standards For Expert Panel, Best-estimate Diagnosis, and Longitudinal Expert All Data (LEAD) Methods. VL - 141 UR - https://stacks.cdc.gov/view/cdc/261356 ER -
Epidemiology and Genotypic Diversity of Rhinovirus in School-age Children With Acute Respiratory Illnesses Seeking Medical Care.

Banerjee, Dithi ;

Schuster, Jennifer E.

August 2025 | Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology, 2025, v. 179

Rhinovirus (RV) associated acute respiratory illness (ARI) data come mostly from infants and young children. We present data from 5 to 17-year-olds to characterize RV species A, B and C.During December 1, 2016-Nov 30, 2017, seven U.S. New Vaccine Surveillance Network (NVSN) sites performed active pediatric ARI surveillance of inpatients (IP) and em ...

10/09/2026

Supporting Files

Title : Epidemiology and Genotypic Diversity of Rhinovirus in School-age Children With Acute Respiratory Illnesses Seeking Medical Care. Personal Author(s) : Banerjee, Dithi;Schuster, Jennifer E.;Midgley, Claire M.;Lee, Brian;Moffatt, Mary;Lively, Joana Y.;Toepfer, Ariana P.;Weinberg, Geoffrey A.;Boom, Julie A.;Sahni, Leila C.;Avadhanula, Vasanthi;Piedra, Pedro A.;Staat, Mary Allen;Payne, Daniel C.;Halasa, Natasha;Williams, John V.;Hickey, Robert W.;Michaels, Marian G.;Englund, Janet A.;Klein, Eileen J.;Sasidharan, A.;Rha, Brian;Harrison, Christopher J.;Selvarangan, Rangaraj; Published Date : August 2025 Pages in Document : 105806 (16 pdf pages) Source : Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology, 2025, v. 179 DOI : https://doi.org/10.1016/j.jcv.2025.105806 Journal Title : Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
Banerjee, D., Schuster, J. E., Midgley, C. M., Lee, B., Moffatt, M., Lively, J. Y., Toepfer, A. P., Weinberg, G. A., Boom, J. A., Sahni, L. C., Avadhanula, V., Piedra, P. A., Staat, M. A., Payne, D. C., Halasa, N., Williams, J. V., Hickey, R. W., Michaels, M. G., Englund, J. A., ... Selvarangan, R. (2025). Epidemiology and Genotypic Diversity of Rhinovirus in School-age Children With Acute Respiratory Illnesses Seeking Medical Care. Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology, 179. https://doi.org/10.1016/j.jcv.2025.105806

Banerjee, Dithi, Jennifer E. Schuster, Claire M. Midgley, Brian Lee, Mary Moffatt, Joana Y. Lively, and Ariana P. Toepfer, et al.. "Epidemiology and Genotypic Diversity of Rhinovirus in School-age Children With Acute Respiratory Illnesses Seeking Medical Care." Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology 179 (2025). https://doi.org/10.1016/j.jcv.2025.105806.

Banerjee, Dithi, et al. "Epidemiology and Genotypic Diversity of Rhinovirus in School-age Children With Acute Respiratory Illnesses Seeking Medical Care." Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology, vol. 179, 2025. Stacks. https://doi.org/10.1016/j.jcv.2025.105806.
Export RIS Citation Information. TY - Journal Article AU - Banerjee, Dithi AU - Schuster, Jennifer E. AU - Midgley, Claire M. AU - Lee, Brian AU - Moffatt, Mary AU - Lively, Joana Y. AU - Toepfer, Ariana P. AU - Weinberg, Geoffrey A. AU - Boom, Julie A. AU - Sahni, Leila C. AU - Avadhanula, Vasanthi AU - Piedra, Pedro A. AU - Staat, Mary Allen AU - Payne, Daniel C. AU - Halasa, Natasha AU - Williams, John V. AU - Hickey, Robert W. AU - Michaels, Marian G. AU - Englund, Janet A. AU - Klein, Eileen J. AU - Sasidharan, A. AU - Rha, Brian AU - Harrison, Christopher J. AU - Selvarangan, Rangaraj AB - Rhinovirus (RV) associated acute respiratory illness (ARI) data come mostly from infants and young children. We present data from 5 to 17-year-olds to characterize RV species A, B and C. AB - During December 1, 2016-Nov 30, 2017, seven U.S. New Vaccine Surveillance Network (NVSN) sites performed active pediatric ARI surveillance of inpatients (IP) and emergency department (ED) patients using molecular platforms to detect multiple respiratory pathogens. RV or RV/enterovirus (EV) positive specimens without co-detections were sequenced. Demographic and clinical data collected via parent interview and chart review were analyzed descriptively by RV species, month, and hospital setting, using chi-squared tests for comparisons. AB - RV or RV/EV was detected in 581/2298 (25.3 %) ARI patients; 529 were single detections, 516 of these had sufficient sample for sequencing, and 420 (81.4 %) yielded sequence results: RV-A (183, 35.5 %), RV-B (16, 3.1 %), RV-C (210, 40.7 %), non-typeable RV (2, 0.4 %), and EV (9, 1.7 %). Among 52 RV-A, 8 RV-B and 44 RV-C unique types identified, A49 (32, 61.5 %), B6 (5, 62.5 %) and C15 (22, 50 %) were predominant. History of asthma was reported in 65.4 % RV-A, 50 % RV-B and 78.5 % RV-C patients (p = 0.005). Hospitalization occurred in 63.4 % RV-A, 37.5 % RV-B and 71.4 % RV-C patients (p = 0.012). RV-C detections peaked during winter and RV-A peaked during summer-fall. AB - RV exhibited genetic diversity in 5-17-year-old ARI patients, and circulation differed by RV species. Among children seeking care in ED or hospital settings, with confirmed RV or RV/EV single detections, hospitalization was more common with RV-A and -C than RV-B. AB - Author manuscript AN - cdc:261355 C4 - PMC12798460 DO - https://doi.org/10.1016/j.jcv.2025.105806 J2 - Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology KW - Genetic Variation KW - Child KW - Rhinovirus KW - Adolescent KW - Genotype KW - Female KW - Acute Disease KW - Male KW - Respiratory Tract Infections KW - Humans KW - Child, Preschool KW - Picornaviridae Infections KW - Rhinovirus KW - Genotypic diversity KW - School-aged children KW - Multi-site KW - Humans KW - Child KW - Adolescent KW - Child, Preschool KW - Male KW - Rhinovirus KW - Female KW - Picornaviridae Infections KW - Respiratory Tract Infections KW - Genotype KW - Genetic Variation KW - Acute Disease LA - eng PY - 2025 T2 - Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology T2 - Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology, 2025, v. 179 TI - Epidemiology and Genotypic Diversity of Rhinovirus in School-age Children With Acute Respiratory Illnesses Seeking Medical Care. VL - 179 UR - https://stacks.cdc.gov/view/cdc/261355 ER -
Defining Aedes Aegypti Density Thresholds For Preventing Human Arboviral Infections.

Barrera, Roberto ;

Acevedo-Soto, Verónica

July 2025 | Acta Tropica, 2025, v. 267

Effective control of local dengue virus transmission requires reducing the population of mosquitoes below a critical density threshold. Aedes aegypti density thresholds can serve as targets for intervention effectiveness. Most thresholds have been identified by correlating vector densities with pathogen transmission events. However, despite previou ...

10/09/2026

Supporting Files

Title : Defining Aedes Aegypti Density Thresholds For Preventing Human Arboviral Infections. Personal Author(s) : Barrera, Roberto;Acevedo-Soto, Verónica;Ruiz-Valcarcel, Jose;Medina, Joanelis;Rivera, Reinaldo;Otero, Luisa;Tosado, Rafael;Medina, Freddy A.;Saavedra, Rafael;Miranda, Julieanne;Ryff, Kyle;Brown, Grayson;Madewell, Zachary J.;Waterman, Stephen H.;Paz-Bailey, Gabriela; Published Date : July 2025 Pages in Document : 107688 (21 pdf pages) Source : Acta Tropica, 2025, v. 267 DOI : https://doi.org/10.1016/j.actatropica.2025.107688 Journal Title : Acta Tropica
Barrera, R., Acevedo-Soto, V., Ruiz-Valcarcel, J., Medina, J., Rivera, R., Otero, L., Tosado, R., Medina, F. A., Saavedra, R., Miranda, J., Ryff, K., Brown, G., Madewell, Z. J., Waterman, S. H., & Paz-Bailey, G. (2025). Defining Aedes Aegypti Density Thresholds For Preventing Human Arboviral Infections. Acta Tropica, 267. https://doi.org/10.1016/j.actatropica.2025.107688

Barrera, Roberto, Verónica Acevedo-Soto, Jose Ruiz-Valcarcel, Joanelis Medina, Reinaldo Rivera, Luisa Otero, and Rafael Tosado, et al.. "Defining Aedes Aegypti Density Thresholds For Preventing Human Arboviral Infections." Acta Tropica 267 (2025). https://doi.org/10.1016/j.actatropica.2025.107688.

Barrera, Roberto, et al. "Defining Aedes Aegypti Density Thresholds For Preventing Human Arboviral Infections." Acta Tropica, vol. 267, 2025. Stacks. https://doi.org/10.1016/j.actatropica.2025.107688.
Export RIS Citation Information. TY - Journal Article AU - Barrera, Roberto AU - Acevedo-Soto, Verónica AU - Ruiz-Valcarcel, Jose AU - Medina, Joanelis AU - Rivera, Reinaldo AU - Otero, Luisa AU - Tosado, Rafael AU - Medina, Freddy A. AU - Saavedra, Rafael AU - Miranda, Julieanne AU - Ryff, Kyle AU - Brown, Grayson AU - Madewell, Zachary J. AU - Waterman, Stephen H. AU - Paz-Bailey, Gabriela AB - Effective control of local dengue virus transmission requires reducing the population of mosquitoes below a critical density threshold. Aedes aegypti density thresholds can serve as targets for intervention effectiveness. Most thresholds have been identified by correlating vector densities with pathogen transmission events. However, despite previous descriptive research there is a need for rigorously controlled field studies to clarify the interactions between Ae. aegypti density and human infections. We report on a multi-arm cluster randomized field trial aimed at determining the number of female Ae. aegypti mosquitoes below which dengue outbreaks are limited. We implemented four mosquito control treatments in a dose-response trial, using zero to three Autocidal Gravid Ovitraps (AGO traps) per house across study neighborhoods in Caguas, Puerto Rico from January 2021 to June 2024. We anticipated that significant reductions in Ae. aegypti populations would indicate a threshold density if low or no prevalence of dengue viruses was observed in mosquitoes or antibodies in residents through IgM and IgG serological testing. Results showed that female Ae. aegypti densities decreased by 44 %, 60 %, and 80 % in clusters with one, two, and three traps/house, respectively. The expected number of dengue-infected mosquitoes per thousand were 2.01, 1.70, 0.60, and 0.36 in clusters with zero, one, two, and three traps/house, respectively. Increases in dengue IgG antibody prevalence from 2022 to 2023 were noted only among residents aged 1-10 years, with rates of 25 %, 18 %, 6 %, and 5.9 % corresponding to the number of traps used. To reduce dengue incidence, local populations of Ae. aegypti should be kept below 4 females per AGO trap per week. AB - Author manuscript AN - cdc:261354 C4 - PMC13207729 DO - https://doi.org/10.1016/j.actatropica.2025.107688 J2 - Acta Tropica KW - Female KW - Population Density KW - Dengue Virus KW - Animals KW - Dengue KW - Arbovirus Infections KW - Aedes KW - Mosquito Control KW - Immunoglobulin G KW - Antibodies, Viral KW - Male KW - Humans KW - Mosquito Vectors KW - Adult KW - Aedes aegypti KW - dengue KW - mosquito surveillance KW - mosquito control KW - threshold density KW - cluster randomized trial KW - Animals KW - Aedes KW - Female KW - Humans KW - Mosquito Vectors KW - Mosquito Control KW - Population Density KW - Dengue KW - Dengue Virus KW - Immunoglobulin G KW - Arbovirus Infections KW - Male KW - Adult KW - Antibodies, Viral LA - eng PY - 2025 T2 - Acta Tropica T2 - Acta Tropica, 2025, v. 267 TI - Defining Aedes Aegypti Density Thresholds For Preventing Human Arboviral Infections. VL - 267 UR - https://stacks.cdc.gov/view/cdc/261354 ER -
Borderline Acceleration in Blood Epigenetic Age of Unclear Biological Importance in Knee Osteoarthritis Progression: Specimens and Data From the Osteoarthritis Initiative and Johnston County Osteoarthritis Project.

Brawner, Cindy Miranda ;

Sturdy, Cassandra

March 2026 | Osteoarthritis and Cartilage, 2026, v. 34, no. 3

Aging is a strong risk factor for osteoarthritis (OA). Previous studies have not found accelerated blood epigenetic aging in OA patients generally. The goal of this study was to evaluate peripheral blood epigenetic aging rates among OA patient subgroups.Genome-wide baseline blood DNA methylation data from the Osteoarthritis Initiative (n = 554) and ...

10/09/2026

Supporting Files

Title : Borderline Acceleration in Blood Epigenetic Age of Unclear Biological Importance in Knee Osteoarthritis Progression: Specimens and Data From the Osteoarthritis Initiative and Johnston County Osteoarthritis Project. Personal Author(s) : Brawner, Cindy Miranda;Sturdy, Cassandra;Arbeeva, Liubov;Golightly, Yvonne M.;Nelson, Amanda E.;Jeffries, Matlock A.; Published Date : March 2026 Pages in Document : 372-379 (15 pdf pages) Source : Osteoarthritis and Cartilage, 2026, v. 34, no. 3 DOI : https://doi.org/10.1016/j.joca.2025.05.010 Journal Title : Osteoarthritis and Cartilage
Brawner, C. M., Sturdy, C., Arbeeva, L., Golightly, Y. M., Nelson, A. E., & Jeffries, M. A. (2026). Borderline Acceleration in Blood Epigenetic Age of Unclear Biological Importance in Knee Osteoarthritis Progression: Specimens and Data From the Osteoarthritis Initiative and Johnston County Osteoarthritis Project. Osteoarthritis and Cartilage, 34(3). https://doi.org/10.1016/j.joca.2025.05.010

Brawner, Cindy Miranda, Cassandra Sturdy, Liubov Arbeeva, Yvonne M. Golightly, Amanda E. Nelson, and Matlock A. Jeffries. "Borderline Acceleration in Blood Epigenetic Age of Unclear Biological Importance in Knee Osteoarthritis Progression: Specimens and Data From the Osteoarthritis Initiative and Johnston County Osteoarthritis Project." Osteoarthritis and Cartilage 34, no. 3 (2026). https://doi.org/10.1016/j.joca.2025.05.010.

Brawner, Cindy Miranda, et al. "Borderline Acceleration in Blood Epigenetic Age of Unclear Biological Importance in Knee Osteoarthritis Progression: Specimens and Data From the Osteoarthritis Initiative and Johnston County Osteoarthritis Project." Osteoarthritis and Cartilage, vol. 34, no. 3, 2026. Stacks. https://doi.org/10.1016/j.joca.2025.05.010.
Export RIS Citation Information. TY - Journal Article AU - Brawner, Cindy Miranda AU - Sturdy, Cassandra AU - Arbeeva, Liubov AU - Golightly, Yvonne M. AU - Nelson, Amanda E. AU - Jeffries, Matlock A. AB - Aging is a strong risk factor for osteoarthritis (OA). Previous studies have not found accelerated blood epigenetic aging in OA patients generally. The goal of this study was to evaluate peripheral blood epigenetic aging rates among OA patient subgroups. AB - Genome-wide baseline blood DNA methylation data from the Osteoarthritis Initiative (n = 554) and Johnston County Osteoarthritis Project (n = 128) were generated using Illumina MethylationEPICv1 arrays on baseline samples of OA progressors (radiographic and/or pain progression in 2-5 years) vs. non-progressors. Epigenetic age was calculated using Horvath, GrimAge, PhenoAge, Horvath-IEAA, Hannum, Horvath-SkinBlood, and DunedinPACE calculators and epigenetic age acceleration was compared. Age-associated proteins were imputed using GrimAge and generalized logistic models developed to differentiate progressor groups. AB - Borderline epigenetic age acceleration was found among radiographic progressors using the SkinBlood calculator (difference in epigenetic age acceleration, ΔEAA=1.5 years, q = 0.02), dual progressors (pain+radiographic) (ΔEAA = 1.2y, q = 0.05) and any progressor (pain+radiographic+dual) (ΔEAA = 1.1y, q = 0.02), although this was less than the reported error of the calculator (2.5 years). Radiographic progressors also exhibited accelerated epigenetic aging using the PhenoAge calculator (ΔEAA = 2.1y, q = 0.02). Imputed age protein-based models showed marginal performance for radiographic progression (area under the curve (AUC) = 0.63) and poor performance for other progressor types (pain AUC=0.54, dual AUC=0.52, any AUC = 0.57). Proteins chosen most frequently during modeling had prior links to OA (i.e., GDF8, MATN3, and interleukin 18). AB - No meaningful difference in epigenetic age was seen among radiographic OA using 5 of 7 aging calculators, with minimal and likely not-clinically-relevant epigenetic age acceleration using the SkinBlood and PhenoAge calculators. AB - Author manuscript AN - cdc:261353 C4 - PMC12354273 DO - https://doi.org/10.1016/j.joca.2025.05.010 IS - 3 J2 - Osteoarthritis and Cartilage KW - Aging KW - Epigenesis, Genetic KW - DNA Methylation KW - Female KW - Aged KW - Male KW - Middle Aged KW - Humans KW - Disease Progression KW - Osteoarthritis, Knee KW - Humans KW - Osteoarthritis, Knee KW - Disease Progression KW - Male KW - Female KW - Middle Aged KW - DNA Methylation KW - Aged KW - Epigenesis, Genetic KW - Aging LA - eng PY - 2026 T2 - Osteoarthritis and Cartilage T2 - Osteoarthritis and Cartilage, 2026, v. 34, no. 3 TI - Borderline Acceleration in Blood Epigenetic Age of Unclear Biological Importance in Knee Osteoarthritis Progression: Specimens and Data From the Osteoarthritis Initiative and Johnston County Osteoarthritis Project. VL - 34 UR - https://stacks.cdc.gov/view/cdc/261353 ER -
Conditions of Work That Impact the Health Behaviors of Long-Haul Truck Drivers.

Aryal, Ashamsa ;

Casteel, Carri

September 2025 | Journal of Occupational and Environmental Medicine, 2025, v. 67, no. 9

We sought to describe conditions of work that impact the health of long-haul truck drivers in the context of the Worker Well-being Framework.We conducted semistructured interviews with 33 incoming and current workers, including drivers. Interviews were analyzed and categorized into the five domains of the Worker Well-being Framework.The physical en ...

10/09/2026

Supporting Files

Title : Conditions of Work That Impact the Health Behaviors of Long-Haul Truck Drivers. Personal Author(s) : Aryal, Ashamsa;Casteel, Carri;Janssen, Brandi;Fethke, Nathan;Buikema, Brenda;Cho, Hyunkeun (Ryan);TePoel, Megan;Rohlman, Diane; Published Date : September 2025 Pages in Document : e649-e654 (15 pdf pages) Source : Journal of Occupational and Environmental Medicine, 2025, v. 67, no. 9 DOI : https://doi.org/10.1097/JOM.0000000000003451 Journal Title : Journal of Occupational and Environmental Medicine
Aryal, A., Casteel, C., Janssen, B., Fethke, N., Buikema, B., Cho, H. (., TePoel, M., & Rohlman, D. (2025). Conditions of Work That Impact the Health Behaviors of Long-Haul Truck Drivers. Journal of Occupational and Environmental Medicine, 67(9). https://doi.org/10.1097/JOM.0000000000003451

Aryal, Ashamsa, Carri Casteel, Brandi Janssen, Nathan Fethke, Brenda Buikema, Hyunkeun (Ryan) Cho, Megan TePoel, and Diane Rohlman. "Conditions of Work That Impact the Health Behaviors of Long-Haul Truck Drivers." Journal of Occupational and Environmental Medicine 67, no. 9 (2025). https://doi.org/10.1097/JOM.0000000000003451.

Aryal, Ashamsa, et al. "Conditions of Work That Impact the Health Behaviors of Long-Haul Truck Drivers." Journal of Occupational and Environmental Medicine, vol. 67, no. 9, 2025. Stacks. https://doi.org/10.1097/JOM.0000000000003451.
Export RIS Citation Information. TY - Journal Article AU - Aryal, Ashamsa AU - Casteel, Carri AU - Janssen, Brandi AU - Fethke, Nathan AU - Buikema, Brenda AU - Cho, Hyunkeun (Ryan) AU - TePoel, Megan AU - Rohlman, Diane AB - We sought to describe conditions of work that impact the health of long-haul truck drivers in the context of the Worker Well-being Framework. AB - We conducted semistructured interviews with 33 incoming and current workers, including drivers. Interviews were analyzed and categorized into the five domains of the Worker Well-being Framework. AB - The physical environment contributes to unhealthy behaviors (eg, limited access to healthy foods, physical activity, noise). Drivers emphasized that industry policies and culture prioritized customer service over worker well-being. AB - Drivers and students had different perceptions about personal responsibility and motivation regarding health behaviors, with students focusing on individual solutions instead of organizational solutions. These insights are essential for developing strategies to create healthier work environments and improve the well-being of long-haul truck drivers. AB - Author manuscript AN - cdc:261352 C4 - PMC12354055 DO - https://doi.org/10.1097/JOM.0000000000003451 IS - 9 J2 - Journal of Occupational and Environmental Medicine KW - Female KW - Working Conditions KW - Interviews as Topic KW - Young Adult KW - Occupational Health KW - Truck Drivers KW - Automobile Driving KW - Exercise KW - Motivation KW - Students KW - Male KW - Health Behavior KW - Humans KW - Middle Aged KW - Time Factors KW - Sedentary Behavior KW - Adult KW - truck drivers KW - conditions of work KW - health behaviors KW - Total Worker Health KW - ® KW - WellBQ KW - occupational safety and health KW - qualitative study KW - Truck Drivers KW - Health Behavior KW - Motivation KW - Interviews as Topic KW - Automobile Driving KW - Occupational Health KW - Time Factors KW - Working Conditions KW - Students KW - Exercise KW - Sedentary Behavior KW - Humans KW - Male KW - Female KW - Young Adult KW - Adult KW - Middle Aged LA - eng PY - 2025 T2 - Journal of Occupational and Environmental Medicine T2 - Journal of Occupational and Environmental Medicine, 2025, v. 67, no. 9 TI - Conditions of Work That Impact the Health Behaviors of Long-Haul Truck Drivers. VL - 67 UR - https://stacks.cdc.gov/view/cdc/261352 ER -

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