Coronavirus Disease 2019 (COVID-19) in a Patient with Disseminated Histoplasmosis and HIV—A Case Report from Argentina and Literature Review

Details

• Alternative Title:
  J Fungi (Basel)
• Personal Author:
  Messina, Fernando A. ; Marin, Emmanuel ; Caceres, Diego H. ; Romero, Mercedes ; Depardo, Roxana ; Priarone, Maria M. ; Rey, Laura ; Vázquez, Mariana ; Verweij, Paul E. ; Chiller, Tom M. ; Santiso, Gabriela
• Description:
  The disease caused by the new SARS-CoV-2, known as Coronavirus disease 2019 (COVID-19), was first identified in China in December 2019 and rapidly spread around the world. Coinfections with fungal pathogens in patients with COVID-19 add challenges to patient care. We conducted a literature review on fungal coinfections in patients with COVID-19. We describe a report of a patient with disseminated histoplasmosis who was likely infected with SARS-CoV-2 and experienced COVID-19 during hospital care in Buenos Aires, Argentina. This patient presented with advanced HIV disease, a well-known factor for disseminated histoplasmosis; on the other hand, we suspected that COVID-19 was acquired during hospitalization but there is not enough evidence to support this hypothesis. Clinical correlation and the use of specific | and COVID-19 rapid diagnostics assays were key to the timely diagnosis of both infections, permitting appropriate treatment and patient care.
• Subjects:
  Case Report Coronavirus Infections COVID-19 Histoplasma Histoplasmosis
• Source:
  J Fungi (Basel). 2020; 6(4)
• Pubmed ID:
  33182836
• Pubmed Central ID:
  PMC7711963
• Document Type:
  Journal Article
• Volume:
  6
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:f5427a5caec205476380c449ea4a2b4ff7f7135260948862faec10bc50653d03
• Download URL:
  https://stacks.cdc.gov/view/cdc/98894/cdc_98894_DS1.pdf
• File Type:
  [PDF - 1.31 MB ]