Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples

Morley, Gabriella L.; Taylor, Stephen; Jossi, Sian; Perez-Toledo, Marisol; Faustini, Sian E.; Marcial-Juarez, Edith; Shields, Adrian M.; Goodall, Margaret; Allen, Joel D.; Watanabe, Yasunori; Newby, Maddy L.; Crispin, Max; Drayson, Mark T.; Cunningham, Adam F.; Richter, Alex G.; O’Shea, Matthew K.

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Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples

Supporting Files

September 24 2020
By Morley, Gabriella L. ; Taylor, Stephen ; Jossi, Sian ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Morley, Gabriella L. ; Taylor, Stephen ; Jossi, Sian ; Perez-Toledo, Marisol ; Faustini, Sian E. ; Marcial-Juarez, Edith ; Shields, Adrian M. ; Goodall, Margaret ; Allen, Joel D. ; Watanabe, Yasunori ; Newby, Maddy L. ; Crispin, Max ; Drayson, Mark T. ; Cunningham, Adam F. ; Richter, Alex G. ; O’Shea, Matthew K.
Description:

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.
Subjects:

Antibodies, Viral Case-Control Studies Coronavirus Infections/diagnosis COVID-19 Serological Testing COVID-19/diagnosis Dried Blood Spot Testing Dried Blood Spot Testing / Methods* Humans Predictive Value Of Tests SARS-CoV-2 / Immunology
Source:

Emerg Infect Dis. 26(12):2970-2973
Pubmed ID:

32969788
Pubmed Central ID:

PMC7706975
Document Type:

Journal Article
Funding:

UM1 AI144462/AI/NIAID NIH HHS/United States ; WT_/Wellcome Trust/United Kingdom
Volume:

26
Issue:

12
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:a07fde3b4e9b0a21e37cb00822011963b060f79efee537d7d8018d7c226c11f6
Download URL:

https://stacks.cdc.gov/view/cdc/98451/cdc_98451_DS1.pdf
File Type:

[PDF - 702.69 KB ]

File Language:

English

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