Systematic Review and Meta-Analyses of Incidence for Group B Streptococcus Disease in Infants and Antimicrobial Resistance, China

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Ding, Yijun ; Wang, Yajuan ; Hsia, Yingfen ; Russell, Neal ; Heath, Paul T.
• Description:
  We performed a systematic review and meta-analysis of the incidence, case-fatality rate (CFR), isolate antimicrobial resistance patterns, and serotype and sequence type distributions for invasive group B Streptococcus (GBS) disease in infants <1-89 days of age in China. We searched the PubMed/Medline, Embase, Wanfang, and China National Knowledge Infrastructure databases for research published during January 1, 2000-March 16, 2018, and identified 64 studies. Quality of included studies was assessed by using Cochrane tools. Incidence and CFR were estimated by using random-effects meta-analyses. Overall incidence was 0.55 (95% CI 0.35-0.74) cases/1,000 live births, and the CFR was 5% (95% CI 3%-6%). Incidence of GBS in young infants in China was higher than the estimated global incidence (0.49 cases/1,000 live births) and higher than previous estimates for Asia (0.3 cases/1,000 live births). Our findings suggest that implementation of additional GBS prevention efforts in China, including maternal vaccination, could be beneficial.
• Subjects:
  Anti-Bacterial Agents Drug Resistance, Bacterial Humans Incidence Infant Streptococcal Infections Streptococcus Agalactiae
• Source:
  Emerg Infect Dis. 26(11):2651-2659
• Pubmed ID:
  33079042
• Pubmed Central ID:
  PMC7588546
• Document Type:
  Journal Article
• Place as Subject:
  China
• Location:
  Asia
• Volume:
  26
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:aa40488eedb5d50686838d0cbd279f59b1e1f6da4df664662ba9cc27c54f80d2
• Download URL:
  https://stacks.cdc.gov/view/cdc/96893/cdc_96893_DS1.pdf
• File Type:
  [PDF - 1.02 MB ]