Etiology of Prelingual Hearing Loss in the Universal Newborn Hearing Screening Era: A Scoping Review

Details

• Journal Article:
  Otolaryngol Head Neck Surg
• Personal Author:
  Satterfield-Nash, Ashley ; Umrigar, Ayesha ; Lanzieri, Tatiana M.
• Description:
  Objective. ; To conduct a scoping review on etiologic investigation of prelingual hearing loss among children <2 years of age in the era of universal newborn hearing screening (UNHS). ; Data Sources. ; PubMed, Embase, PsycInfo, CINAHL, and Cochrane Library databases. ; Review Methods. ; We searched for articles published from January 1, 1998, to February 19, 2020. We reviewed studies that (1) included children identified with either congenital or delayed-onset hearing loss before 2 years of age among cohorts who had undergone UNHS and (2) investigated ≥1 etiologies of hearing loss. We defined hearing loss as congenital when confirmed after UNHS failure and as delayed onset when diagnosed after ≥1 assessments with normal hearing. ; Results. ; Among 2069 unique citations, 115 studies met criteria for full-text assessment, and 20 met our inclusion criteria. Six studies tested children diagnosed with hearing loss for genetic etiology, 9 for congenital cytomegalovirus (CMV) infection, and 5 for both. Among 1787 children with congenital hearing loss and etiologic investigation, 933 (52.2%) were tested for genetic mutations and 1021 (57.1%) for congenital CMV infection. The proportion of congenital hearing loss cases attributable to genetic etiology ranged between 7.7% and 83.3% and to congenital CMV infection between 0.0% and 32.0%. ; Conclusion. ; Data are lacking on the identification and etiology of delayed-onset hearing loss in children <2 years of age in the UNHS era. The proportion of congenital hearing loss cases attributable to genetic etiologies and congenital CMV infection appears to vary widely.
• Keywords:
  • prelingual hearing loss
  • universal newborn hearing screening
  • genetic hearing loss
  • congenital CMV
  • cytomegalovirus
  • Cytomegalovirus Infections
  • Evoked Potentials, Auditory, Brain Stem
  • Hearing Loss
  • Hearing Tests
  • Humans
  More +
• Source:
  Otolaryngol Head Neck Surg. 163(4):662-670
• DOI:
  http://dx.doi.org/10.1177/0194599820921870
• Pubmed ID:
  32423335
• Pubmed Central ID:
  PMC7541667
• Document Type:
  Text ; Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Genre:
  Journal Article
• Volume:
  163
• Issue:
  4
• Download URL:
  https://stacks.cdc.gov/view/cdc/95043/cdc_95043_DS1.pdf
• File Type:
  [PDF - 353.61 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:a82abd08cb12024c468c032a66c0dbf902358781f10059dc7661df61e273c02d04d9edeb1ad2a3b44c727597b53789f2f0b6d4454a94f93589a2f99a7d48bd57