Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  L’Huillier, Arnaud G. ; Torriani, Giulia ; Pigny, Fiona ; Kaiser, Laurent ; Eckerle, Isabella
• Description:
  Children do not seem to drive transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We isolated culture-competent virus in vitro from 12 (52%) of 23 SARS-CoV-2-infected children; the youngest was 7 days old. Our findings show that symptomatic neonates, children, and teenagers shed infectious SARS-CoV-2, suggesting that transmission from them is plausible.
• Subjects:
  Adolescent Betacoronavirus Cell Line Child Child, Preschool Coronavirus Infections Covid-19 Expedited Female Humans Infant Infant, Newborn Male Nasopharynx Pandemics Pneumonia, Viral Rna, Viral Viral Load Virus Cultivation Virus Replication

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• Source:
  Emerg Infect Dis. 26(10):2494-2497
• Pubmed ID:
  32603290
• Pubmed Central ID:
  PMC7510703
• Document Type:
  Journal Article
• Place as Subject:
  Switzerland
• Location:
  Europe
• Volume:
  26
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:87543effcab5a4469ab50df93dae257965697627c28b86ba1844579d496f4702
• Download URL:
  https://stacks.cdc.gov/view/cdc/94781/cdc_94781_DS1.pdf
• File Type:
  [PDF - 337.80 KB ]