Sequential Acquisition of Human Papillomavirus Infection at Genital and Anal Sites, Liuzhou, China

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Wei, Feixue ; Su, Yingying ; Cui, Xuelian ; Yu, Xiaojuan ; Li, Yafei ; Song, Qiaoqiao ; Yin, Kai ; Huang, Shoujie ; Li, Mingqiang ; Zhang, Jun ; Wu, Ting ; Xia, Ningshao
• Description:
  Little is known about the risk for acquiring a concordant human papillomavirus (HPV) infection in a genital (or anal) site after an anal (or genital) HPV infection. We collected 3 sets of anogenital specimens at 6-month intervals from 2,309 men and 2,378 women in Liuzhou, China, and tested these specimens for HPV. The risk for sequential anal HPV infection in participants with a previous genital HPV infection was higher than for participants without an infection (hazard ratio [HR] 4.4, 95% CI 3.4-5.8 for women and HR 2.6, 95% CI 1.4-4.6 for men). For sequential genital HPV infection, women with a previous anal infection had a higher risk (HR 1.9, 95% CI 1.2-3.1), but no major difference was found for men (HR 0.7, 95% CI 0.2-1.9). Our study indicates that autoinoculation might play a major role in anogenital HPV transmission, in addition to direct sexual intercourse, especially for anal infection in women.
• Subjects:
  Anal Sites Autoinoculation Genital Sites HPV Human Papillomavirus Infection Observational Cohort Study Research Sequential Infection Sexually Transmitted Infections Viruses

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• Source:
  Emerg Infect Dis. 26(10):2387-2393
• Pubmed ID:
  32946717
• Pubmed Central ID:
  PMC7510729
• Document Type:
  Journal Article
• Place as Subject:
  China
• Location:
  Asia
• Volume:
  26
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:9ee14b57d5833797403dc08d7c667a68b016fc164ef5296e0ee812d8052571e6
• Download URL:
  https://stacks.cdc.gov/view/cdc/94751/cdc_94751_DS1.pdf
• File Type:
  [PDF - 1.39 MB ]