Anti-Müllerian hormone levels in nurses working night shifts

Details

• Alternative Title:
  Arch Environ Occup Health
• Personal Author:
  Johnson, Candice Y. ; Tanz, Lauren J. ; Lawson, Christina C. ; Howards, Penelope P. ; Bertone-Johnson, Elizabeth R. ; Eliassen, A. Heather ; Schernhammer, Eva S. ; Rich-Edwards, Janet W.
• Description:
  Our objective was to examine associations between night shift work and serum anti-Müllerian hormone (AMH) levels. We analyzed 1,537 blood samples from premenopausal female nurses in the Nurses' Health Study II, assayed for AMH. Rotating or permanent night shifts worked in the two weeks before blood collection and years of rotating night shift work were obtained via questionnaire. We found no associations between recent night shifts or rotating night shift work and AMH. The median difference in AMH was 0.3 (95% CI: -0.4, 0.8) ng/mL for ≥5 versus 0 recent night shifts and -0.1 (95% CI: -0.4, 0.3) ng/mL for ≥6 versus 0 years of rotating night shift work. Although we found no associations between night shift work and AMH, this does not preclude associations between night shift work and fertility operating through other mechanisms.
• Subjects:
  Adult Anti-Mullerian Hormone Article Female Humans Nurses Work Schedule Tolerance
• Source:
  Arch Environ Occup Health. :1-8
• Pubmed ID:
  30945620
• Pubmed Central ID:
  PMC6776712
• Document Type:
  Journal Article
• Funding:
  R01 CA178949/CA/NCI NIH HHS/United States ; R01 OH009803/OH/NIOSH CDC HHS/United States ; R01 CA067262/CA/NCI NIH HHS/United States ; UM1 CA176726/CA/NCI NIH HHS/United States ; R01OH009803/ACL/ACL HHS/United States ; CC999999/ImCDC/Intramural CDC HHS/United States ; R01 HD078517/HD/NICHD NIH HHS/United States
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:3edced8cacc3c5cc278c01804ac8a64bd235d142380ad2405b6cfed8fd8505c6
• Download URL:
  https://stacks.cdc.gov/view/cdc/94597/cdc_94597_DS1.pdf
• File Type:
  [PDF - 168.50 KB ]