Work schedule and physical factors in relation to fecundity in nurses
Published Date:Aug 06 2015
Source:Occup Environ Med. 72(11):777-783.
Pubmed Central ID:PMC4609294
Funding:200-2013-M-54978/PHS HHS/United States
CC999999/Intramural CDC HHS/United States
T32 DK007703/DK/NIDDK NIH HHS/United States
T32 HD060454/HD/NICHD NIH HHS/United States
T32DK007703/DK/NIDDK NIH HHS/United States
T32HD060454/HD/NICHD NIH HHS/United States
To evaluate the association of work schedule and physical factors with fecundity.
Women currently employed outside the home and trying to get pregnant (n=1739) in the Nurses’ Health Study 3 cohort (2010–2014) were included in this analysis. Work schedule and physical labour were self-reported on the baseline questionnaire, and every 6 months thereafter the women reported the duration of their ongoing pregnancy attempt. Multivariable accelerated failure time models were used to estimate time ratios (TR) and 95% CIs.
Among the 1739 women (median age=33 years, 93% Caucasian) the estimated proportions of women not pregnant after 12 and 24 months were 16% and 5%, respectively. None of the various shift work patterns were associated with duration of pregnancy attempt (as a surrogate for fecundity). However, women working >40 h/week had a 20% (95% CI 7 to 35%) longer median duration of pregnancy attempt compared to women working 21–40 h/week (p-trend=0.005). Women whose work entailed heavy lifting or moving (ie, 25+ pounds) >15 times/day also had a longer median duration of pregnancy attempt (adjusted TR=1.49; 95% CI 1.20 to 1.85) compared to women who never lifted or moved heavy loads (p-trend=0.002). The association between heavy moving and lifting and duration of pregnancy attempt was more pronounced among overweight or obese women (body mass index, BMI<25: TR=1.17; 95% CI 0.88 to 1.56; BMI≥25: TR=2.03, 95% CI 1.48 to 2.79; p-interaction=0.007).
Working greater than 40 h per week and greater frequency of lifting or moving a heavy load were associated with reduced fecundity in a cohort of nurses planning pregnancy.
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