Modified Antiretroviral Treatment Access Study (MARTAS): A Randomized Controlled Trial of the Efficacy of a Linkage-to-Care Intervention Among HIV-Positive Patients in Ukraine

Details

• Alternative Title:
  AIDS Behav
• Personal Author:
  Neduzhko, Oleksandr ; Postnov, Oleksandr ; Sereda, Yuliia ; Kulchynska, Roksolana ; Bingham, Trista ; Myers, Janet J. ; Flanigan, Timothy ; Kiriazova, Tetiana
• Description:
  Between October 2015 and March 2018, we conducted the Modified Antiretroviral Treatment Access Study (MARTAS), a nurse-delivered case management intervention to improve linkage-to-care for persons recently tested HIV positive. Adult participants from nine urban clinics in three regions of Ukraine were randomized to either MARTAS or standard of care (SOC) using individual, parallel, two-arm design. The main study outcome was linkage-to-care (defined as registration at an HIV clinic) within a 3-month period from enrollment in the study. Intention-to-treat analysis of MARTAS (n = 135) versus SOC (n = 139) showed intervention efficacy in linkage to HIV care (84.4% vs. 33.8%; adjusted RR 2.45; 95% CI 1.72, 3.47; p < 0.001). MARTAS is recommended for implementation in Ukraine and may be helpful in other countries with similar gaps in linkage-to-care. Clinicaltrials.gov registration number: NCT02338024.
• Subjects:
  Adolescent Adult Aged Anti-Retroviral Agents Case Management Female HIV Infections Humans Male Middle Aged Patient-Centered Care Patient Acceptance Of Health Care Pregnancy Retention In Care Standard Of Care Treatment Outcome Ukraine

  More +
• Keywords:
  HIV Care Linkage-to-care Nurse Case Management Randomized Controlled Trial
• Source:
  AIDS Behav. 24(11):3142-3154
• Pubmed ID:
  32333208
• Pubmed Central ID:
  PMC7508967
• Document Type:
  Journal Article
• Funding:
  U01 GH000752/GH/CGH CDC HHSUnited States/ ; 3U01GH000752-02S1./U.S. President's Emergency Plan for AIDS Relief/
• Volume:
  24
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:661d33e8c2e10bb4da5eaadfe33cc3a4d207ed4f010a68f9b30b3639f2031f20d0d5a6fea0c80e9ad68b8b256c214925a5648366f5e155a987bcc5f570a4eb0d
• Download URL:
  https://stacks.cdc.gov/view/cdc/94158/cdc_94158_DS1.pdf
• File Type:
  [PDF - 825.68 KB ]