i
Residential proximity to greenhouse crops and pesticide exposure (via acetylcholinesterase activity) assessed from childhood through adolescence
-
9 2020
Source: Environ Res. 188:109728 -
Alternative Title:Environ Res
-
Publisher's site:
-
Personal Author:
-
Description:Background
Off-target drift of pesticides from farms increases the risk of pesticide exposure of people living nearby. Cholinesterase inhibitors (i.e. organophosphates and carbamates) are frequently used in agriculture and inhibit acetylcholinesterase (AChE) activity. Greenhouse agriculture is an important production method, but it is unknown how far pesticide drift from greenhouses can extend and expose people living nearby.
Methods
This study included 1156 observations from 3 exams (2008, Apr 2016 and Jul-Oct of 623 children aged 4-to-17 years living in agricultural communities in Ecuador. AChE, a physiological marker of cholinesterase inhibitor exposure, was measured in blood. Geographic positioning of greenhouses and homes were obtained using GPS receivers and satellite imagery. Distances between homes and the nearest greenhouse edge, and areas of greenhouse crops within various buffer zones around homes were calculated. Repeated-measures regression adjusted for hemoglobin and other covariates estimated change in AChE relative to distance from greenhouses.
Results
The pooled mean (SD) of AChE activity was 3.58 U/mL (0.60). The median (25th-75th %tile) residential distance to crops was 334 m (123, 648) and crop area within 500 m of homes (non-zero values only) was 18,482 m2 (7115, 61,841). Residential proximity to greenhouse crops was associated with lower AChE activity among children living within 275m of crops (AChE difference per 100m of proximity [95% CI]= −0.10 U/mL [−0.20, −0.006]). Lower AChE activity was associated with greater crop area within 500m of homes (AChE difference per 1000m2 [95% CI]= −0.026 U/mL [−0.040, −0.012]) and especially within 150m (−0.037 U/mL [−0.065, −0.007]).
Conclusions
Residential proximity to floricultural greenhouses, especially within 275m, was associated with lower AChE activity among children, reflecting greater cholinesterase inhibitor exposure from pesticide drift. Analyses of residential proximity and crop areas near homes yielded complementary findings. Mitigation of off-target drift of pesticides from crops onto nearby homes is recommended.
-
Subject:
-
Source:
-
Pubmed ID:32798937
-
Pubmed Central ID:PMC7483309
-
Document Type:
-
Funding:
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
Details:
Supporting Files
More +