Incidence and Seroprevalence of Avian Influenza in a Cohort of Backyard Poultry Growers, Egypt, August 2015–March 2019

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Gomaa, Mokhtar R. ; El Rifay, Amira S. ; Abu Zeid, Dina ; Elabd, Mona A. ; Elabd, Eman ; Kandeil, Ahmed ; Shama, Noura M. Abo ; Kamel, Mina N. ; Marouf, Mohamed A. ; Barakat, Ahmed ; Refaey, Samir ; Naguib, Amal ; McKenzie, Pamela P. ; Webby, Richard J. ; Ali, Mohamed A. ; Kayali, Ghazi ; Gomaa, Mokhtar R. ; El Rifay, Amira S. ; Abu Zeid, Dina ; Elabd, Mona A. ; Elabd, Eman ; Kandeil, Ahmed ; Shama, Noura M. Abo ; Kamel, Mina N. ; Marouf, Mohamed A. ; Barakat, Ahmed ; Refaey, Samir ; Naguib, Amal ; McKenzie, Pamela P. ; Webby, Richard J. ; Ali, Mohamed A. ; Kayali, Ghazi
• Description:
  Currently enzootic avian influenza H5N1, H9N2, and H5N8 viruses were introduced into poultry in Egypt in 2006, 2011, and 2016, respectively. Infections with H5N1 and H9N2 were reported among poultry-exposed humans. We followed 2,402 persons from households raising backyard poultry from 5 villages in Egypt during August 2015-March 2019. We collected demographic, exposure, and health condition data and annual serum samples from each participant and obtained swab samples from participants reporting influenza-like illness symptoms. We performed serologic and molecular analyses and detected 4 cases of infection with H5N1 and 3 cases with H9N2. We detected very low seroprevalence of H5N1 antibodies and no H5N8 antibodies among the cohort; up to 11% had H9 antibodies. None of the exposure, health status, or demographic variables were related to being seropositive. Our findings indicate that avian influenza remains a public health risk in Eqypt, but infections may go undetected because of their mild or asymptomatic nature.
• Subjects:
  Animals Humans Incidence Influenza, Human Influenza A Virus, H5N1 Subtype Influenza A Virus, H9N2 Subtype Influenza In Birds Poultry Seroepidemiologic Studies
• Source:
  Emerg Infect Dis. 26(9):2129-2136 ; Emerg Infect Dis. 26(9):2129-2136
• Pubmed ID:
  32818403
• Pubmed Central ID:
  PMC7454077
• Document Type:
  Journal Article
• Place as Subject:
  Egypt
• Location:
  Africa ; Africa
• Volume:
  26
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6fca74c3b23d0c566154e59a649fd794489d7524bb237e3ca3dfdc660aa771d1
• Download URL:
  https://stacks.cdc.gov/view/cdc/92996/cdc_92996_DS1.pdf
• File Type:
  [PDF - 391.29 KB ]