Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Mögling, Ramona ; Meijer, Adam ; Berginc, Natasa ; Bruisten, Sylvia ; Charrel, Remi ; Coutard, Bruno ; Eckerle, Isabella ; Enouf, Vincent ; Hungnes, Olav ; Korukluoglu, Gülay ; Kossyvakis, Thanos ; Mentis, Andreas ; Molenkamp, Richard ; Muradrasoli, Shaman ; Papa, Anna ; Pigny, Fiona ; Thirion, Laurence ; van der Werf, Sylvie ; Reusken, Chantal
• Description:
  The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe simultaneously implemented SARS-CoV-2 diagnostics. These laboratories reported in February 2020 that commercial primer and probe batches for SARS-CoV-2 detection were contaminated with synthetic control material, causing delays of regional testing roll-out in various countries.
• Subjects:
  Artifacts Betacoronavirus Clinical Laboratory Techniques Coronavirus Infections Covid-19 Delayed Diagnosis Diagnostic Tests, Routine DNA Primers DNA Probes Humans Laboratories Pandemics Pathology, Molecular Pneumonia, Viral Reagent Kits, Diagnostic Reverse Transcriptase Polymerase Chain Reaction Rna Replicase Viral Envelope Proteins

  More +
• Source:
  Emerg Infect Dis. 26(8):1944-1946
• Pubmed ID:
  32433015
• Pubmed Central ID:
  PMC7392437
• Document Type:
  Journal Article
• Genre:
  Letter
• Place as Subject:
  Europe
• Volume:
  26
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4944a2bf131d47aa66ec31b4a6b72ac2c327c380f1fbd7f5b8055e0f2765a5df
• Download URL:
  https://stacks.cdc.gov/view/cdc/91582/cdc_91582_DS1.pdf
• File Type:
  [PDF - 688.94 KB ]