Epidemiology of Legionnaires’ Disease, Hong Kong, China, 2005−2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Leung, Yiu-Hong ; Lam, Chau-Kuen ; Cheung, Yung-Yan ; Chan, Chi-Wai ; Chuang, Shuk-Kwan
• Description:
  We reviewed findings of clinical, epidemiologic, and environmental investigations for 288 confirmed case-patients with Legionnaires' disease reported in Hong Kong, China, during January 2005-December 2015. We found that chronic renal failure/impairment (adjusted odds ratio [aOR] 4.09), chronic pulmonary diseases (aOR 3.22), malignancy (aOR 3.04), and heart diseases (aOR 2.15) were independently associated with a higher risk for severe Legionnaires' disease. However, patients with hyperlipidemia had a lower risk for severe outcome (aOR 0.17). Legionella positivity rate was 22% for 1,904 water samples collected. We found a higher positivity rate in summer months (28%-30%), which corroborated with months of highest rainfalls. Our novel finding that Legionnaires' disease patients with hyperlipidemia had a lower risk for severe outcome deserves further study to confirm the observation and ascertain the underlying reason.
• Subjects:
  Humans Legionella Legionella Pneumophila Legionnaires' Disease Water Microbiology
• Source:
  Emerg Infect Dis. 26(8):1695-1702
• Pubmed ID:
  32687025
• Pubmed Central ID:
  PMC7392469
• Document Type:
  Journal Article
• Place as Subject:
  China ; Hong Kong
• Location:
  Asia
• Volume:
  26
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:61ba4d45385c1b6ae63ba34568595f281d640116472c3bb3a1709964dcaad02a
• Download URL:
  https://stacks.cdc.gov/view/cdc/91528/cdc_91528_DS1.pdf
• File Type:
  [PDF - 1.40 MB ]