Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France

Rodriguez, Christophe; Gricourt, Guillaume; Ndebi, Melissa; Demontant, Vanessa; Poiteau, Lila; Burrel, Sonia; Boutolleau, David; Woerther, Paul-Louis; Calvez, Vincent; Stroer, Sebastian; Pawlotsky, Jean-Michel

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Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France

Supporting Files Public Domain

Jun 2020
By Rodriguez, Christophe ; Gricourt, Guillaume ; Ndebi, Melissa ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Rodriguez, Christophe ; Gricourt, Guillaume ; Ndebi, Melissa ; Demontant, Vanessa ; Poiteau, Lila ; Burrel, Sonia ; Boutolleau, David ; Woerther, Paul-Louis ; Calvez, Vincent ; Stroer, Sebastian ; Pawlotsky, Jean-Michel
Description:

We report the discovery of a new orthobunyavirus, Cristoli virus, by means of shotgun metagenomics. The virus was identified in an immunodepressed patient with fatal encephalitis. Full-length genome sequencing revealed high-level expression of a virulence factor, possibly explaining the severity of the infection. The patient's recent history suggests circulation in France.
Subjects:

Cristoli Virus Dispatch Fatal Encephalitis Caused By Cristoli Virus, An Emerging Orthobunyavirus, France France Meningitis/Encephalitis Orthobunyavirus Shotgun Metagenomics Viruses
Source:

Emerg Infect Dis. 26(6):1287-1290
Pubmed ID:

32441621
Pubmed Central ID:

PMC7258463
Document Type:

Journal Article
Volume:

26
Issue:

6
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:09ade209bf736b60bb82134357ac0a52d265f5ef2c5491d615658278cabe9ea7
Download URL:

https://stacks.cdc.gov/view/cdc/88881/cdc_88881_DS1.pdf
File Type:

[PDF - 699.82 KB ]

File Language:

English

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