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Weight Change in Older Adults and Risk of Frailty
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2020
Source: J Frailty Aging. 9(2):74-81 -
Alternative Title:J Frailty Aging
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Description:OBJECTIVE:
A 5% change in weight is a significant predictor for frailty and obesity. We ascertained how self-reported weight change over the lifespan impacts rates of frailty in older adults.
METHODS:
We identified 4,984 subjects ≥60 years with body composition measures from the National Health and Nutrition Examination Survey. An adapted version of Fried’s frailty criteria was used as the primary outcome. Self-reported weight was assessed at time current,1 and 10 years earlier and at age 25. Weight changes between each time point were categorized as ≥ 5%, ≤5% or neutral. Logistic regression assessed the impact of weight change on the outcome of frailty.
RESULTS:
Among 4,984 participants, 56.5% were female, mean age was 71.1 years, and mean BMI was 28.2kg/m2. A weight loss of ≥ 5% had a higher association with frailty compared to current weight, age 25 (OR 2.94 [1.72,5.02]), 10 years ago (OR 1.68 [1.05,2.69]), and 1 year ago (OR 1.55 [1.02,2.36]). Weight gain in the last year was associated with increased rate of frailty (1.59 [1.09,2.32]).
CONCLUSION:
There is an association between frailty and weight loss over time while only weight gain in the last year has an association with frailty.
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Pubmed ID:32259180
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Pubmed Central ID:PMC7202674
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