Details:

Alternative Title:
J Frailty Aging
Publisher's site:
http://dx.doi.org/10.14283/jfa.2019.44
Personal Author:
Crow, Rebecca S. ; Petersen, Curtis L. ; Cook, Summer B. ; Stevens, Courtney J. ; Titus, Alexander J. ; ... More +
Crow, Rebecca S. ; Petersen, Curtis L. ; Cook, Summer B. ; Stevens, Courtney J. ; Titus, Alexander J. ; Mackenzie, Todd A. ; Batsis, John A. ; Less -
Description:
OBJECTIVE: A 5% change in weight is a significant predictor for frailty and obesity. We ascertained how self-reported weight change over the lifespan impacts rates of frailty in older adults. METHODS: We identified 4,984 subjects ≥60 years with body composition measures from the National Health and Nutrition Examination Survey. An adapted version of Fried’s frailty criteria was used as the primary outcome. Self-reported weight was assessed at time current,1 and 10 years earlier and at age 25. Weight changes between each time point were categorized as ≥ 5%, ≤5% or neutral. Logistic regression assessed the impact of weight change on the outcome of frailty. RESULTS: Among 4,984 participants, 56.5% were female, mean age was 71.1 years, and mean BMI was 28.2kg/m2. A weight loss of ≥ 5% had a higher association with frailty compared to current weight, age 25 (OR 2.94 [1.72,5.02]), 10 years ago (OR 1.68 [1.05,2.69]), and 1 year ago (OR 1.55 [1.02,2.36]). Weight gain in the last year was associated with increased rate of frailty (1.59 [1.09,2.32]). CONCLUSION: There is an association between frailty and weight loss over time while only weight gain in the last year has an association with frailty.
Subject:
[+]
Aged
Article
Body-Weight Trajectory
Female
Frail Elderly
Frailty
Humans
Male
Middle Aged
Nutrition Surveys
Obesity
Pre-frailty
Sarcopenia
Self Report

Source:
J Frailty Aging. 9(2):74-81
Pubmed ID:
32259180
Pubmed Central ID:
PMC7202674
Document Type:
Journal Article ;
Funding:
T32 MH073553/MH/NIMH NIH HHSUnited States/ ; P30 CA023108/CA/NCI NIH HHSUnited States/ ; U48 DP005018/DP/NCCDPHP CDC HHSUnited States/ ; U48DP005018/ACL/ACL HHSUnited States/ ; T32 LM012204/LM/NLM NIH HHSUnited States/ ; ... More +
T32 MH073553/MH/NIMH NIH HHSUnited States/ ; P30 CA023108/CA/NCI NIH HHSUnited States/ ; U48 DP005018/DP/NCCDPHP CDC HHSUnited States/ ; U48DP005018/ACL/ACL HHSUnited States/ ; T32 LM012204/LM/NLM NIH HHSUnited States/ ; K23 AG051681/AG/NIA NIH HHSUnited States/ ; WT_/Wellcome TrustUnited Kingdom/ ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d06e69d9b3b0db47bf912b44c108facb85080d3792fe062c88aef8caf38cfbd9
File Type:

Supporting Files

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  	NIHMS1583020-supplement-supp1.docx	docx

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