Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Naik, Shilpa ; Robinson, Matthew L. ; Alexander, Mallika ; Chandanwale, Ajay ; Sambarey, Pradip ; Kinikar, Aarti ; Bharadwaj, Renu ; Sapkal, Gajanan N. ; Chebrolu, Puja ; Deshpande, Prasad ; Kulkarni, Vandana ; Nimkar, Smita ; Mave, Vidya ; Gupta, Amita ; Mathad, Jyoti
• Description:
  Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017-January 2018, we screened pregnant women during antenatal surveillance for symptoms of mosquitoborne diseases (fever only, fever with conjunctivitis, fever with rash, or all 3 symptoms) within the previous 15 days. Of 5,843 pregnant women screened, 52 were enrolled and tested for dengue, chikungunya, and Zika viruses by using a Trioplex real-time reverse transcription PCR. Of 49 who had complete results, 7 (14%) were dengue positive. Of these ocular pain was seen in 4 (57%) and conjunctivitis in 7 (100%). Intensified symptom screening using conjunctivitis, in addition to rash, in pregnant women with fever might improve dengue case detection and can be included in routine symptom screening during pregnancy.
• Subjects:
  Chikungunya Fever Dengue Female Humans Pregnancy Zika Virus Zika Virus Infection
• Source:
  Emerg Infect Dis. 26(4):738-743
• Pubmed ID:
  32186485
• Pubmed Central ID:
  PMC7101120
• Document Type:
  Journal Article
• Place as Subject:
  India
• Volume:
  26
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:cb2e675459b259a8a71183915ed95fe583d3ee468e03ff2fbc1fcde3bb191600
• Download URL:
  https://stacks.cdc.gov/view/cdc/86492/cdc_86492_DS1.pdf
• File Type:
  [PDF - 439.90 KB ]