Decreased Susceptibility to Azithromycin in Clinical Shigella Isolates Associated with HIV and Sexually Transmitted Bacterial Diseases, Minnesota, USA, 2012–2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Eikmeier, Dana ; Talley, Pamela ; Bowen, Anna ; Leano, Fe ; Dobbins, Ginette ; Jawahir, Selina ; Gross, Annastasia ; Huspeni, Dawn ; La Pointe, Allison ; Meyer, Stephanie ; Smith, Kirk
• Description:
  Shigellosis outbreaks caused by Shigella with decreased susceptibility to azithromycin (DSA-Shigella) among men who have sex with men (MSM) have been reported worldwide. We describe sexual health indicators and antimicrobial drug resistance for shigellosis cases in Minnesota, USA. We analyzed a sample of isolates received during 2012-2015 and cross-referenced cases with the Minnesota Department of Health Sexually Transmitted Disease Database to ascertain patients' HIV status and recent chlamydia, gonorrhea, and syphilis infections. Of 691 Shigella isolates, 46 (7%) were DSA-Shigella; 91% of DSA-Shigella patients were men, of whom 60% were living with HIV. Among men, those with DSA-Shigella infection had greater odds of living with HIV, identifying as MSM, or having a recent diagnosis of a sexually transmitted disease. DSA-Shigella was associated with MSM, HIV infection, and recent sexually transmitted disease. To decrease spread of DSA-Shigella, interventions targeted at communities at high risk are needed.
• Subjects:
  Antimicrobial Resistance Azithromycin Bacteria Decreased Susceptibility To Azithromycin Decreased Susceptibility To Azithromycin In Clinical Shigella Isolates Associated With Hiv And Sexually Transmitted Bacterial Diseases, Minnesota, Usa, 2012–2015 Dsa Enteric Infections Hiv Infections Men Who Have Sex With Men Msm Sexually Transmitted Diseases Sexually Transmitted Infections (Stis) Shigella Shigellosis Stds Synopsis

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• Source:
  Emerg Infect Dis. 26(4):667-674
• Pubmed ID:
  32186495
• Pubmed Central ID:
  PMC7101095
• Document Type:
  Journal Article
• Place as Subject:
  Minnesota
• Location:
  North America
• Volume:
  26
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:39e7036a62dfc56d86854ca7ee801a6a27184def844818d50e9a3531b8a24d7f
• Download URL:
  https://stacks.cdc.gov/view/cdc/86481/cdc_86481_DS1.pdf
• File Type:
  [PDF - 492.15 KB ]