Risk Factors for Complicated Lymphadenitis Caused by Nontuberculous Mycobacteria in Children

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Kuntz, Martin ; Kohlfürst, Daniela S. ; Feiterna-Sperling, Cornelia ; Krüger, Renate ; Baumann, Ulrich ; Buchtala, Laura ; Elling, Roland ; Grote, Veit ; Hübner, Johannes ; Hufnagel, Markus ; Kaiser-Labusch, Petra ; Liese, Johannes ; Otto, Eva-Maria ; Rose, Markus A. ; Schneider, Christian ; Schuster, Volker ; Seidl, Maximilian ; Sommerburg, Olaf ; Vogel, Markus ; von Bernuth, Horst ; Weiß, Michael ; Zimmermann, Theodor ; Nieters, Alexandra ; Zenz, Werner ; Henneke, Philipp
• Corporate Authors:
  for the NTMkids Consortium
• Description:
  Nontuberculous mycobacteria (NTM) are an emerging cause of infections, including chronic lymphadenitis in children. To identify risk factors for NTM lymphadenitis, particularly complicated disease, we collected epidemiologic, clinical, and microbiological data on 138 cases of NTM lymphadenitis in children across 13 centers in Germany and Austria. We assessed lifestyle factors but did not identify specific risk behaviors. We noted that more cases of NTM lymphadenitis occurred during cold months than during warm months. Moreover, we noted female sex and age <5.5 years as potential risk factors. Complete extirpation of the affected lymph node appeared to be the best therapeutic measure. We integrated the study data to develop a simple risk score to predict unfavorable clinical outcomes for NTM lymphadenitis.
• Subjects:
  Bacteria Children Epidemiology Lymphadenitis Nontuberculous Mycobacteria Research Risk Factors Risk Factors For Complicated Lymphadenitis Caused By Nontuberculous Mycobacteria In Children Tuberculosis And Other Mycobacteria
• Source:
  Emerg Infect Dis. 26(3):579-586
• Pubmed ID:
  32091372
• Pubmed Central ID:
  PMC7045849
• Document Type:
  Journal Article
• Place as Subject:
  Germany ; Austria
• Location:
  Europe
• Volume:
  26
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b0afb3e47e9c1adb1abdf42c01f4c871ce2118237758bde8212491a7e6ae898c
• Download URL:
  https://stacks.cdc.gov/view/cdc/85691/cdc_85691_DS1.pdf
• File Type:
  [PDF - 693.72 KB ]