Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
de Boer, Pieter T. ; de Lange, Marit M.A. ; Wielders, Cornelia C.H. ; Dijkstra, Frederika ; van Roeden, Sonja E. ; ... More +
de Boer, Pieter T. ; de Lange, Marit M.A. ; Wielders, Cornelia C.H. ; Dijkstra, Frederika ; van Roeden, Sonja E. ; Bleeker-Rovers, Chantal P. ; Oosterheert, Jan Jelrik ; Schneeberger, Peter M. ; van der Hoek, Wim Less -
Description:
In the aftermath of a large Q fever (QF) epidemic in the Netherlands during 2007-2010, new chronic QF (CQF) patients continue to be detected. We developed a health-economic decision model to evaluate the cost-effectiveness of a 1-time screening program for CQF 7 years after the epidemic. The model was parameterized with spatial data on QF notifications for the Netherlands, prevalence data from targeted screening studies, and clinical data from the national QF database. The cost-effectiveness of screening varied substantially among subpopulations and geographic areas. Screening that focused on cardiovascular risk patients in areas with high QF incidence during the epidemic ranged from cost-saving to €31,373 per quality-adjusted life year gained, depending on the method to estimate the prevalence of CQF. The cost per quality-adjusted life year of mass screening of all older adults was €70,000 in the most optimistic scenario.
Subject:
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Bacteria
Cost-effectiveness
Cost-effectiveness Of Screening Program For Chronic Q Fever, The Netherlands
Coxiella Burnetii
Economic Evaluation
Q Fever
Research
Screening
Zoonoses

Source:
Emerg Infect Dis. 26(2):238-246
Pubmed ID:
31961297
Pubmed Central ID:
PMC6986831
Document Type:
Journal Article
Place as Subject:
Netherlands
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:514d7b32c8591447bcd85455c05e310eb506b6d024917afd29c17de22be6ae9a
File Type:

Supporting Files

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