Cost-effectiveness of Screening Program for Chronic Q Fever, the Netherlands

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  de Boer, Pieter T. ; de Lange, Marit M.A. ; Wielders, Cornelia C.H. ; Dijkstra, Frederika ; van Roeden, Sonja E. ; Bleeker-Rovers, Chantal P. ; Oosterheert, Jan Jelrik ; Schneeberger, Peter M. ; van der Hoek, Wim
• Description:
  In the aftermath of a large Q fever (QF) epidemic in the Netherlands during 2007-2010, new chronic QF (CQF) patients continue to be detected. We developed a health-economic decision model to evaluate the cost-effectiveness of a 1-time screening program for CQF 7 years after the epidemic. The model was parameterized with spatial data on QF notifications for the Netherlands, prevalence data from targeted screening studies, and clinical data from the national QF database. The cost-effectiveness of screening varied substantially among subpopulations and geographic areas. Screening that focused on cardiovascular risk patients in areas with high QF incidence during the epidemic ranged from cost-saving to €31,373 per quality-adjusted life year gained, depending on the method to estimate the prevalence of CQF. The cost per quality-adjusted life year of mass screening of all older adults was €70,000 in the most optimistic scenario.
• Subjects:
  Bacteria Cost-effectiveness Cost-effectiveness Of Screening Program For Chronic Q Fever, The Netherlands Coxiella Burnetii Economic Evaluation Q Fever Research Screening Zoonoses
• Source:
  Emerg Infect Dis. 26(2):238-246
• Pubmed ID:
  31961297
• Pubmed Central ID:
  PMC6986831
• Document Type:
  Journal Article
• Place as Subject:
  Netherlands
• Location:
  Europe
• Volume:
  26
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:514d7b32c8591447bcd85455c05e310eb506b6d024917afd29c17de22be6ae9a
• Download URL:
  https://stacks.cdc.gov/view/cdc/84813/cdc_84813_DS1.pdf
• File Type:
  [PDF - 2.59 MB ]