Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Abbate, Jessica L. ; Becquart, Pierre ; Leroy, Eric ; Ezenwa, Vanessa O. ; Roche, Benjamin ;
Abbate, Jessica L. ; Becquart, Pierre ; Leroy, Eric ; Ezenwa, Vanessa O. ; Roche, Benjamin ; Less -
Description:
An association between malaria and risk for death among patients with Ebola virus disease has suggested within-host interactions between Plasmodium falciparum parasites and Ebola virus. To determine whether such an interaction might also influence the probability of acquiring either infection, we used a large snapshot surveillance study from rural Gabon to test if past exposure to Ebola virus is associated with current infection with Plasmodium spp. during nonepidemic conditions. We found a strong positive association, on population and individual levels, between seropositivity for antibodies against Ebola virus and the presence of Plasmodium parasites in the blood. According to a multiple regression model accounting for other key variables, antibodies against Ebola virus emerged as the strongest individual-level risk factor for acquiring malaria. Our results suggest that within-host interactions between malaria parasites and Ebola virus may underlie epidemiologic associations.
Subject:
[+]
Disease
Ebola Virus
Ecology
Epidemiology
Exposure To Ebola Virus And Risk For Infection With Malaria Parasites, Gabon
Malaria
Occurrence
Parasites
Pathogen-pathogen Interactions
Plasmodium
Populations At Risk
Prevalence
Research
Risk Factors
Surveillance
Viruses

Source:
Emerg Infect Dis. 26(2):229-237
Pubmed ID:
31829919
Pubmed Central ID:
PMC6986822
Document Type:
Journal Article ;
Place as Subject:
Gabon ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:c10cd8ef0ba9df101ed72c4927cbdd05428df9925c04faefcdb9edcd47d84ca7
File Type:

Supporting Files

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