The Impact of Human Immunodeficiency Virus Exposure on Respiratory Syncytial Virus–associated Severe Respiratory Illness in South African Infants, 2011–2016

Details

• Alternative Title:
  Clin Infect Dis
• Personal Author:
  McMorrow, Meredith L. ; Tempia, Stefano ; Walaza, Sibongile ; Treurnicht, Florette K. ; Moyes, Jocelyn ; Cohen, Adam L. ; Pretorius, Marthi ; Hellferscee, Orienka ; Wolter, Nicole ; von Gottberg, Anne ; Nguweneza, Arthemon ; McAnerney, Johanna M. ; Naby, Fathima ; Mekgoe, Omphile ; Venter, Marietjie ; Madhi, Shabir A. ; Cohen, Cheryl
• Description:
  From 2011 through 2016, we conducted surveillance for severe respiratory illness in infants. Human immunodeficiency virus exposure significantly increased the risk of respiratory syncytial virus (RSV)-associated hospitalization in infants aged <5 months. More than 60% of RSV-associated hospitalizations occurred in the first 4 months of life and may be preventable through maternal vaccination or birth-dose monoclonal antibody.
• Subjects:
  Coinfection Female History, 21st Century HIV Infections Hospitalization Humans Infant Infant, Newborn Male Mass Screening Respiratory Syncytial Virus, Human Respiratory Syncytial Virus Infections Severity Of Illness Index

  More +
• Source:
  Clin Infect Dis. 69(12):2208-2211
• Pubmed ID:
  30963178
• Pubmed Central ID:
  PMC6934254
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHS/United States ; U01 IP001048/IP/NCIRD CDC HHS/United States ; U01IP001048/ACL/ACL HHS/United States
• Place as Subject:
  South Africa
• Volume:
  69
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e1f7ec73851e5b58517c5cf25ec06d2329cfe4e1a033bdfd56b1f7e3793e4801
• Download URL:
  https://stacks.cdc.gov/view/cdc/83846/cdc_83846_DS1.pdf
• File Type:
  [PDF - 236.68 KB ]