Guideline implementation is effective at reducing proton pump inhibitor use in hematology-oncology units: a multidisciplinary intervention for reducing Clostridioides difficile risk

Details

• Alternative Title:
  Infect Control Hosp Epidemiol
• Personal Author:
  Ziegler, Matthew ; Freyer, Craig ; Landsburg, Daniel ; Pegues, David ; Bilker, Warren ; Hirsh, Rebecca ; Kucharczuk, Colleen ; Gilmar, Cheryl ; Gorman, Theresa ; Palmer, Melissa ; Harker, Christina ; Lightheart, Erin ; Han, Jennifer H.
• Description:
  We implemented a guideline for appropriate acid suppressant use in hematology-oncology patients. This intervention resulted in a sustained reduction in proton pump inhibitor (PPI) use without an increase in rates of gastrointestinal bleeding. Practice guidelines are effective in reducing PPI use, which is associated with risk of Clostridioides difficile infection.
• Subjects:
  Clostridium Infections Gastrointestinal Hemorrhage Hematology Hospital Units Humans Practice Guidelines As Topic Proton Pump Inhibitors Regression Analysis Risk Factors Tertiary Care Centers
• Source:
  Infect Control Hosp Epidemiol. 40(11):1294-1296
• Pubmed ID:
  31466535
• Pubmed Central ID:
  PMC6893867
• Document Type:
  Journal Article
• Funding:
  U54 CK000485/CK/NCEZID CDC HHS/United States ; U54CK000485/ACL/ACL HHS/United States
• Place as Subject:
  Pennsylvania
• Volume:
  40
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:894af6c6a0225fd43ce1413132ed41be1525d3b0507ddbb7017e9e5737921d43
• Download URL:
  https://stacks.cdc.gov/view/cdc/83225/cdc_83225_DS1.pdf
• File Type:
  [PDF - 548.43 KB ]