Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Otsuji, Ken; Fukuda, Kazumasa; Ogawa, Midori; Saito, Mitsumasa

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Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Supporting Files Public Domain

November 2019
By Otsuji, Ken ; Fukuda, Kazumasa ; Ogawa, Midori ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Otsuji, Ken ; Fukuda, Kazumasa ; Ogawa, Midori ; Saito, Mitsumasa
Description:

Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans. Diphtheria toxin diversification could decrease effectiveness of diphtheria toxoid vaccine and diphtheria antitoxin for preventing and treating illnesses caused by this bacterium.
Subjects:

Amino Acid Sequence Corynebacterium Diphtheria Diphtheria Toxin Diphtheria Toxoid Genetic Variation Humans Mutation Phylogeny Rna, Ribosomal, 16S
Source:

Emerg Infect Dis. 25(11):2122-2123
Pubmed ID:

31625851
Pubmed Central ID:

PMC6810190
Document Type:

Journal Article
Genre:

Letter
Place as Subject:

Japan
Volume:

25
Issue:

11
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:0182b729fd243111913666e00b0dc03a082f6e6ef0276bc42a392c8295254446
Download URL:

https://stacks.cdc.gov/view/cdc/82983/cdc_82983_DS1.pdf
File Type:

[PDF - 474.88 KB ]

File Language:

English

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