Serologic Evidence of Exposure to Highly Pathogenic Avian Influenza H5 Viruses in Migratory Shorebirds, Australia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Wille, Michelle ; Lisovski, Simeon ; Risely, Alice ; Ferenczi, Marta ; Roshier, David ; Wong, Frank Y.K. ; Breed, Andrew C. ; Klaassen, Marcel ; Hurt, Aeron C.
• Description:
  Highly pathogenic avian influenza (HPAI) H5Nx viruses of the goose/Guangdong/96 lineage continue to cause outbreaks in poultry and wild birds globally. Shorebirds, known reservoirs of avian influenza viruses, migrate from Siberia to Australia along the East-Asian-Australasian Flyway. We examined whether migrating shorebirds spending nonbreeding seasons in Australia were exposed to HPAI H5 viruses. We compared those findings with those for a resident duck species. We screened >1,500 blood samples for nucleoprotein antibodies and tested positive samples for specific antibodies against 7 HPAI H5 virus antigens and 2 low pathogenicity avian influenza H5 virus antigens. We demonstrated the presence of hemagglutinin inhibitory antibodies against HPAI H5 virus clade 2.3.4.4 in the red-necked stint (Calidris ruficolis). We did not find hemagglutinin inhibitory antibodies in resident Pacific black ducks (Anas superciliosa). Our study highlights the potential role of long-distance migratory shorebirds in intercontinental spread of HPAI H5 viruses.
• Subjects:
  Australia Avian Influenza Clade 2.3.4.4 H5 Highly Pathogenic HPAI Influenza A Virus Pacific Black Duck Red-necked Stint Research Serologic Evidence Of Exposure To Highly Pathogenic Avian Influenza H5 Virus In Migratory Shorebirds, Australia Serology Shorebirds

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• Source:
  Emerg Infect Dis. 25(10):1903-1910
• Pubmed ID:
  31538564
• Pubmed Central ID:
  PMC6759277
• Document Type:
  Journal Article
• Funding:
  HHSN266200700010C/AI/NIAID NIH HHS/United States
• Volume:
  25
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:ae7f864e8ecdfe7d6e0787d46efc2d2bdd1f592c999b69617c0c82abaa75b731
• Download URL:
  https://stacks.cdc.gov/view/cdc/82967/cdc_82967_DS1.pdf
• File Type:
  [PDF - 1.72 MB ]