Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Jere, Khuzwayo C. ; Bar-Zeev, Naor ; Chande, Adams ; Bennett, Aisleen ; Pollock, Louisa ; Sanchez-Lopez, Pedro F. ; Nakagomi, Osamu ; Tate, Jacqueline E. ; Parashar, Umesh D. ; Heyderman, Robert S. ; French, Neil ; Iturriza-Gomara, Miren ; Cunliffe, Nigel A.
• Description:
  Atypical DS-1-like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1-like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%-96.8%). These findings suggest that vaccine provides protection against these strains despite their emergence coinciding with vaccine introduction.
• Subjects:
  Child, Hospitalized* Child, Preschool Dispatch Female Gastroenteritis / Epidemiology* Gastroenteritis / Prevention & Control Gastroenteritis / Virology Humans Infant Infant, Newborn Male Rotavirus Rotavirus Infections Rotavirus Vaccines Vaccines, Attenuated

  More +
• Source:
  Emerg Infect Dis. 25(9):1734-1737
• Pubmed ID:
  31441761
• Pubmed Central ID:
  PMC6711242
• Document Type:
  Journal Article
• Funding:
  Wellcome Trust/United Kingdom
• Place as Subject:
  Malawi
• Location:
  Africa
• Volume:
  25
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:8821796f53db5a5627eea8ddcff18f436d63cc16ee2b83e1b97ec536b0d6734e
• Download URL:
  https://stacks.cdc.gov/view/cdc/81165/cdc_81165_DS1.pdf
• File Type:
  [PDF - 881.25 KB ]