Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers

Barkati, Sapha; Taher, Hashim Ba; Beauchamp, Elizabeth; Yansouni, Cédric P.; Ward, Brian J.; Libman, Michael D.

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Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers

Sep 2019
By Barkati, Sapha ; Taher, Hashim Ba ; Beauchamp, Elizabeth ; ...
Source: Emerg Infect Dis. 25(9)

[PDF-1.19 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Barkati, Sapha ; Taher, Hashim Ba ; Beauchamp, Elizabeth ; Yansouni, Cédric P. ; Ward, Brian J. ; ... More +

Barkati, Sapha ; Taher, Hashim Ba ; Beauchamp, Elizabeth ; Yansouni, Cédric P. ; Ward, Brian J. ; Libman, Michael D. Less -
Description:

Macaque-related injuries among primate workers can lead to a potentially fatal B virus encephalomyelitis. We describe a decision tool for evaluating the need for antiviral postexposure prophylaxis and provide a retrospective review of the injuries assessed in our center after its implementation in 2010. Among the injuries studied (n = 251), 40.6% were categorized as high-risk (prophylaxis recommended), 44.2% moderate-risk (consider prophylaxis), and 15.1% low-risk (prophylaxis not recommended). Ten percent of low-risk and 98% of high-risk injuries received prophylaxis (p<0.001). Compared with using universal postexposure prophylaxis, using a decision tool can lead to a standardization of practice and a reduction in prescriptions for antiviral medication.
Subjects:

[+]

Antiviral Agents B Virus Decision Tool Herpes B Virus Infection Macacine Alphaherpesvirus 1 Macaque Monkey B Virus Online Report Post-exposure Prophylaxis Primate Workers Research Laboratory Workers Viruses
Source:

Emerg Infect Dis. 25(9)
Pubmed ID:

31441751
Pubmed Central ID:

PMC6711206
Document Type:

Journal Article
Volume:

25
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:8f4acbd6f0e69611dd29bc89e4a780a5a7727cf2e0a3d25cacbeb12be0cf72bb
Download URL:

https://stacks.cdc.gov/view/cdc/81158/cdc_81158_DS1.pdf
File Type:

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	19-0045-F.jpg	jpeg
	19-0045.nxml	xml

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