Occupational exposure and airflow obstruction and self-reported COPD among ever-employed US adults using a COPD-job exposure matrix

Details

• Alternative Title:
  Am J Ind Med
• Personal Author:
  Doney, Brent ; Kurth, Laura ; Halldin, Cara ; Hale, Janet ; Frenk, Steven M.
• Description:
  Introduction:
  
  This study examined the association of spirometry-defined airflow obstruction and self-reported COPD defined as self-reported doctor diagnosed chronic bronchitis or emphysema, with occupational exposure among ever-employed US adults.
  
  Methods:
  
  Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2008 to 2011–2012, a nationally representative study of the non-institutionalized civilian US population. Reported current and/or longest held job were used to create prevalence estimates and prevalence odds ratios (PORs) (adjusted for age, gender, race, and smoking status) for airflow obstruction and self-reported COPD by occupational exposure, determined using both NHANES participants’ selfreported exposures and eight categories of COPD job exposure matrix (JEM) assigned exposures.
  
  Results:
  
  Significant PORs for airflow obstruction and self-reported COPD respectively were observed with self-reported exposure for ≥20 years to mineral dust (POR = 1.44; 95% confidence interval (CI) 1.13–1.85; POR = 1.69; 95% CI 1.17–2.43) and exhaust fumes (POR = 1.65; 95% CI 1.27–2.15; POR = 2.22; 95% CI 1.37–3.58). Airflow obstruction or self-reported` COPD were also associated with COPD-JEM assigned high exposure to mineral dust, combined dust, diesel exhaust, vapor-gas, sensitizers, and overall exposure.
  
  Conclusion:
  
  Airflow obstruction and self-reported COPD are associated with both self-reported and JEM-assigned exposures.
  
  
• Subjects:
  Adult Aged Female Humans Male Middle Aged Nutrition Surveys Occupational Diseases Occupational Exposure Pulmonary Disease, Chronic Obstructive Risk Factors Self Report Smoking Spirometry United States Young Adult

  More +
• Keywords:
  Airflow Obstruction CDC COPD Job Exposure Matrix NHANES Occupational Exposure Prevalence
• Source:
  Am J Ind Med. 62(5):393-403
• Pubmed ID:
  30775792
• Pubmed Central ID:
  PMC6661888
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  62
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:f4f21493a6d1369b653b0dfde876a8d3d49796b683650f45025b4240d87bb1cea1d4945996d754bd0b97a9afc8000910fed2d29be0657a1a166259d4e723fcc9
• Download URL:
  https://stacks.cdc.gov/view/cdc/80230/cdc_80230_DS1.pdf
• File Type:
  [PDF - 126.01 KB ]