Associations Between Concentrations of Vitamin D and Concentrations of Insulin, Glucose, and HbA1c Among Adolescents in the United States

Details

• Alternative Title:
  Diabetes Care
• Personal Author:
  Ford, Earl S. ; Zhao, Guixiang ; Tsai, James ; Li, Chaoyang
• Description:
  OBJECTIVE
  
  Our objective was to examine the associations between concentrations of vitamin D and concentrations of insulin, glucose, and HbA1c in a nationally representative sample of adolescents in the U.S.
  
  RESEARCH DESIGN AND METHODS
  
  We used data for 1,941 adolescents, aged 12–17 years, who participated in the National Health and Nutrition Examination Survey between 2001 and 2006.
  
  RESULTS
  
  Adjusted concentrations of insulin were ~24% lower among male subjects with a concentration of vitamin D ≥75 nmol/L than among male subjects with a concentration of vitamin D <50 nmol/L (P = 0.003). Concentrations of vitamin D were inversely associated with concentrations of glucose only among Mexican American male subjects (P = 0.007). No significant associations between concentrations of vitamin D and HbA1c were detected.
  
  CONCLUSIONS
  
  Our results support an inverse association between concentrations of vitamin D and insulin primarily in adolescent male subjects.
  
  
• Subjects:
  Adolescent Blood Glucose Child Female Hemoglobin A, Glycosylated Humans Insulin Male Original Research Vitamin D
• Source:
  Diabetes Care. 34(3):646-648.
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Volume:
  34
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e3f1f5706b59723b44ac3d3ef79eff223245b46a37bf2ac223d8717c91fe36f9
• Download URL:
  https://stacks.cdc.gov/view/cdc/8019/cdc_8019_DS1.pdf
• File Type:
  [PDF - 72.67 KB ]