Differences in Pancreatic Cancer Incidence Rates and Temporal Trends Across Asian Subpopulations in California (1988-2015)

Details

• Alternative Title:
  Pancreas
• Personal Author:
  Liu, Lihua ; Zhang, Juanjuan ; Deapen, Dennis ; Stern, Mariana C. ; Sipin, Andrea ; Pandol, Stephen J. ; Setiawan, Veronica Wendy
• Description:
  Objective:
  
  Ethnic disparities in pancreatic cancer (PanCan) incidence exist, but little is known about incidence trends in heterogeneous Asian Americans. We examined PanCan incidence and temporal patterns among detailed ethnic populations, including Asian-American subgroups.
  
  Methods:
  
  A total of 71,099 invasive exocrine PanCan cases were identified using the California Cancer Registry between 1988 and 2015. Cases were grouped into mutually exclusive groups of non-Hispanic (NH) white, NH black, Hispanic, NH Asian/Pacific Islander (API), and NH American Indian/Alaska Native. Asians were further identified by specific ethnicity.
  
  Results:
  
  The age-adjusted incidence rates (per 100,000) of PanCan varied significantly across racial/ethnic groups, ranging from the highest of 10.4 in NH blacks to 7.6 in NH whites, 7.1 in Hispanics, 6.2 in NH APIs, and to the lowest of 5.2 in NH American Indian/Alaska Native. Despite the relatively low rate in the NH APIs, the rates across Asian subgroups varied significantly, with rates similar to NH whites in Japanese (8.1) and Koreans (7.5) to the low rate in South Asians (4.4).
  
  Conclusions:
  
  Significant heterogeneity of PanCan incidence in disaggregated Asian Americans are novel findings. These results fill a gap regarding PanCan burden in Asian Americans and underscore the importance of disaggregating ethnic populations in cancer research.
  
  
• Subjects:
  Adult Aged Asian Black Or African American Hispanic Or Latino Humans Incidence Middle Aged Oceanians Pancreas, Exocrine Pancreatic Neoplasms Registries White People

  More +
• Source:
  Pancreas. 48(7):931-933
• Pubmed ID:
  31180980
• Pubmed Central ID:
  PMC6629494
• Document Type:
  Journal Article
• Funding:
  HHSN261201000140C/CA/NCI NIH HHS/United States ; HHSN261201000035I/CA/NCI NIH HHS/United States ; HHSN261201000034C/CA/NCI NIH HHS/United States ; U54 CA233465/CA/NCI NIH HHS/United States ; HHSN261201000035C/CA/NCI NIH HHS/United States ; U58 DP003862/DP/NCCDPHP CDC HHS/United States ; U54 CA233444/CA/NCI NIH HHS/United States ; U54 CA233396/CA/NCI NIH HHS/United States
• Place as Subject:
  California
• Volume:
  48
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:bf9e64b327d8907caa5a4806244bd5c0edfb488f2481867abf081c711069806d
• Download URL:
  https://stacks.cdc.gov/view/cdc/79869/cdc_79869_DS1.pdf
• File Type:
  [PDF - 241.68 KB ]